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PDB: 12512 件

8GY6
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Structure of SARS-CoV-2 RNA-dependent RNA polymerase with gossypol binding
分子名称: Gossypol, Non-structural protein 7, Non-structural protein 8, ...
著者Wang, W, Ren, M, Li, F.
登録日2022-09-21
公開日2023-11-01
実験手法ELECTRON MICROSCOPY
主引用文献Structure of SARS-CoV-2 RNA-dependent RNA polymerase with gossypol binding
To Be Published
5EJC
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Crystal structural of the TSC1-TBC1D7 complex
分子名称: Hamartin, TBC1 domain family member 7
著者Wang, Z, Qin, J, Gong, W, Xu, W.
登録日2015-11-01
公開日2016-03-02
最終更新日2019-11-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural Basis of the Interaction between Tuberous Sclerosis Complex 1 (TSC1) and Tre2-Bub2-Cdc16 Domain Family Member 7 (TBC1D7).
J.Biol.Chem., 291, 2016
3RNT
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CRYSTAL STRUCTURE OF GUANOSINE-FREE RIBONUCLEASE T1, COMPLEXED WITH VANADATE(V), SUGGESTS CONFORMATIONAL CHANGE UPON SUBSTRATE BINDING
分子名称: CALCIUM ION, RIBONUCLEASE T1, VANADATE ION
著者Kostrewa, D, Choe, H.-W, Heinemann, U, Saenger, W.
登録日1989-05-31
公開日1989-10-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of guanosine-free ribonuclease T1, complexed with vanadate (V), suggests conformational change upon substrate binding.
Biochemistry, 28, 1989
1RNT
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RESTRAINED LEAST-SQUARES REFINEMENT OF THE CRYSTAL STRUCTURE OF THE RIBONUCLEASE T1(ASTERISK)2(PRIME)-GUANYLIC ACID COMPLEX AT 1.9 ANGSTROMS RESOLUTION
分子名称: GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE T1 ISOZYME
著者Saenger, W, Arni, R, Heinemann, U, Tokuoka, R.
登録日1987-07-10
公開日1987-10-16
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Restrained Least-Squares Refinement of the Crystal Structure of the Ribonuclease T1(Asterisk)2(Prime)-Guanylic Acid Complex at 1.9 Angstroms Resolution
Acta Crystallogr.,Sect.B, 43, 1987
5FTY
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Structure of surface layer protein SbsC, domains 6-7 (monoclinic form)
分子名称: CALCIUM ION, SURFACE LAYER PROTEIN
著者Dordic, A, Pavkov-Keller, T, Eder, M, Egelseer, E.M, Davis, K, Mills, D, Sleytr, U.B, Kuehlbrandt, W, Vonck, J, Keller, W.
登録日2016-01-18
公開日2017-02-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of Surface Layer Protein Sbsc, Domains 6-7 (Monoclinic Form)
To be Published
1TBQ
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CRYSTAL STRUCTURE OF INSECT DERIVED DOUBLE DOMAIN KAZAL INHIBITOR RHODNIIN IN COMPLEX WITH THROMBIN
分子名称: RHODNIIN, THROMBIN
著者Van De Locht, A, Lamba, D, Bode, W.
登録日1995-03-02
公開日1996-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Two heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombin.
EMBO J., 14, 1995
1TBR
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CRYSTAL STRUCTURE OF INSECT DERIVED DOUBLE DOMAIN KAZAL INHIBITOR RHODNIIN IN COMPLEX WITH THROMBIN
分子名称: RHODNIIN, THROMBIN
著者Van De Locht, A, Lamba, D, Bode, W.
登録日1995-03-03
公開日1996-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Two heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombin.
EMBO J., 14, 1995
1IAG
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BU of 1iag by Molmil
FIRST STRUCTURE OF A SNAKE VENOM METALLOPROTEINASE: A PROTOTYPE FOR MATRIX METALLOPROTEINASES(SLASH)COLLAGENASES
分子名称: ADAMALYSIN II, CALCIUM ION, SULFATE ION, ...
著者Gomis-Rueth, F.-X, Bode, W.
登録日1994-05-09
公開日1994-08-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献First structure of a snake venom metalloproteinase: a prototype for matrix metalloproteinases/collagenases.
EMBO J., 12, 1993
3J40
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Validated Near-Atomic Resolution Structure of Bacteriophage Epsilon15 Derived from Cryo-EM and Modeling
分子名称: gp10, gp7
著者Baker, M.L, Hryc, C.F, Zhang, Q, Wu, W, Jakana, J, Haase-Pettingell, C, Afonine, P.V, Adams, P.D, King, J.A, Jiang, W, Chiu, W.
登録日2013-05-30
公開日2013-07-10
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Validated near-atomic resolution structure of bacteriophage epsilon15 derived from cryo-EM and modeling.
Proc.Natl.Acad.Sci.USA, 110, 2013
2PPS
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BU of 2pps by Molmil
PHOTOSYNTHETIC REACTION CENTER AND CORE ANTENNA SYSTEM (TRIMERIC), ALPHA CARBON ONLY
分子名称: CHLOROPHYLL A, IRON/SULFUR CLUSTER, PHOTOSYSTEM I, ...
著者Krauss, N, Schubert, W.-D, Klukas, O, Fromme, P, Witt, H.T, Saenger, W.
登録日1997-05-27
公開日1998-05-27
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Photosystem I at 4 A resolution represents the first structural model of a joint photosynthetic reaction centre and core antenna system.
Nat.Struct.Biol., 3, 1996
7YW0
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Bacteroides fragilis Hcp5
分子名称: Bacterodales T6SS protein TssD (Hcp)
著者Wen, Y, He, W, Bai, Y.
登録日2022-08-20
公開日2023-08-30
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structure and assembly of type VI secretion system cargo delivery vehicle.
Cell Rep, 42, 2023
5J39
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Crystal Structure of the extended TUDOR domain from TDRD2
分子名称: CACODYLATE ION, Tudor and KH domain-containing protein, UNKNOWN ATOM OR ION
著者Zhang, H, Tempel, W, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2016-03-30
公開日2016-04-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis for arginine methylation-independent recognition of PIWIL1 by TDRD2.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5JBM
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BU of 5jbm by Molmil
Crystal structgure of Cac1 C-terminus
分子名称: Chromatin assembly factor 1 subunit p90
著者Churchill, M.E.A, Liu, W, Zhou, Y.
登録日2016-04-13
公開日2016-10-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Cac1 subunit of histone chaperone CAF-1 organizes CAF-1-H3/H4 architecture and tetramerizes histones.
Elife, 5, 2016
6CUD
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Structure of the human TRPC3 in a lipid-occupied, closed state
分子名称: (2R)-3-hydroxypropane-1,2-diyl dihexanoate, (2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Lu, W, Du, J, Fan, C, Choi, W.
登録日2018-03-25
公開日2018-05-16
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of the human lipid-gated cation channel TRPC3.
Elife, 7, 2018
2BGT
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BU of 2bgt by Molmil
CRYSTAL STRUCTURE OF THE DNA MODIFYING ENZYME BETA-GLUCOSYLTRANSFERASE IN THE PRESENCE AND ABSENCE OF THE SUBSTRATE URIDINE DIPHOSPHOGLUCOSE
分子名称: BETA-GLUCOSYLTRANSFERASE
著者Vrielink, A, Rueger, W, Driessen, H.P.C, Freemont, P.S.
登録日1994-06-09
公開日1995-12-09
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the DNA modifying enzyme beta-glucosyltransferase in the presence and absence of the substrate uridine diphosphoglucose.
EMBO J., 13, 1994
2BGU
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CRYSTAL STRUCTURE OF THE DNA MODIFYING ENZYME BETA-GLUCOSYLTRANSFERASE IN THE PRESENCE AND ABSENCE OF THE SUBSTRATE URIDINE DIPHOSPHOGLUCOSE
分子名称: BETA-GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE
著者Vrielink, A, Rueger, W, Driessen, H.P.C, Freemont, P.S.
登録日1994-06-09
公開日1995-12-09
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the DNA modifying enzyme beta-glucosyltransferase in the presence and absence of the substrate uridine diphosphoglucose.
EMBO J., 13, 1994
2CGA
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BOVINE CHYMOTRYPSINOGEN A. X-RAY CRYSTAL STRUCTURE ANALYSIS AND REFINEMENT OF A NEW CRYSTAL FORM AT 1.8 ANGSTROMS RESOLUTION
分子名称: CHYMOTRYPSINOGEN A
著者Wang, D, Bode, W, Huber, R.
登録日1987-01-16
公開日1987-04-16
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Bovine chymotrypsinogen A X-ray crystal structure analysis and refinement of a new crystal form at 1.8 A resolution.
J.Mol.Biol., 185, 1985
3PRK
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BU of 3prk by Molmil
INHIBITION OF PROTEINASE K BY METHOXYSUCCINYL-ALA-ALA-PRO-ALA-CHLOROMETHYL KETONE. AN X-RAY STUDY AT 2.2-ANGSTROMS RESOLUTION
分子名称: CALCIUM ION, METHOXYSUCCINYL-ALA-ALA-PRO-ALA-CHLOROMETHYL KETONE, PROTEINASE K
著者Wolf, W.M, Bajorath, J, Mueller, A, Raghunathan, S, Singh, T.P, Hinrichs, W, Saenger, W.
登録日1991-08-07
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Inhibition of proteinase K by methoxysuccinyl-Ala-Ala-Pro-Ala-chloromethyl ketone. An x-ray study at 2.2-A resolution.
J.Biol.Chem., 266, 1991
2D2D
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BU of 2d2d by Molmil
Crystal Structure Of SARS-CoV Mpro in Complex with an Inhibitor I2
分子名称: 3C-like proteinase, ETHYL (2E,4S)-4-[((2R)-2-{[N-(TERT-BUTOXYCARBONYL)-L-VALYL]AMINO}-2-PHENYLETHANOYL)AMINO]-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENT-2-ENOATE
著者Yang, H, Bartlam, M, Xue, X, Yang, K, Liang, W, Ding, Y, Rao, Z.
登録日2005-09-08
公開日2005-09-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases.
Plos Biol., 3, 2005
4RSL
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Structure of fructosyl peptide oxidase from E. terrenum
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Fructosyl peptide oxidase, PHOSPHATE ION
著者Gan, W, Gao, F, Xing, K, Jia, M, Liu, H, Gong, W.
登録日2014-11-08
公開日2015-05-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of the substrate specificity of the FPOD/FAOD family revealed by fructosyl peptide oxidase from Eupenicillium terrenum
Acta Crystallogr.,Sect.F, 71, 2015
6O5M
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Tubulin-RB3_SLD-TTL in complex with compound 10bb
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ...
著者Kumar, G, Wang, Y, Li, W, White, S.W.
登録日2019-03-04
公開日2019-07-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1H-Indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) Analogues Targeting the Colchicine Binding Site in Tubulin.
J.Med.Chem., 62, 2019
6O5N
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Tubulin-RB3_SLD-TTL in complex with compound 10ab
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
著者Kumar, G, Wang, Y, Li, W, White, S.W.
登録日2019-03-04
公開日2019-07-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.003 Å)
主引用文献Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1H-Indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) Analogues Targeting the Colchicine Binding Site in Tubulin.
J.Med.Chem., 62, 2019
3J7X
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Capsid Expansion Mechanism Of Bacteriophage T7 Revealed By Multi-State Atomic Models Derived From Cryo-EM Reconstructions
分子名称: Major capsid protein 10A
著者Guo, F, Liu, Z, Fang, P.A, Zhang, Q, Wright, E.T, Wu, W, Zhang, C, Vago, F, Ren, Y, Jakata, J, Chiu, W, Serwer, P, Jiang, W.
登録日2014-08-12
公開日2014-10-15
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Capsid expansion mechanism of bacteriophage T7 revealed by multistate atomic models derived from cryo-EM reconstructions.
Proc.Natl.Acad.Sci.USA, 111, 2014
6O61
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Tubulin-RB3_SLD-TTL in complex with compound ABI-231
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
著者Kumar, G, Wang, Y, Li, W, White, S.W.
登録日2019-03-05
公開日2019-07-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.599 Å)
主引用文献Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1H-Indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) Analogues Targeting the Colchicine Binding Site in Tubulin.
J.Med.Chem., 62, 2019
3J7V
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Capsid Expansion Mechanism Of Bacteriophage T7 Revealed By Multi-State Atomic Models Derived From Cryo-EM Reconstructions
分子名称: Major capsid protein 10A
著者Guo, F, Liu, Z, Fang, P.A, Zhang, Q, Wright, E.T, Wu, W, Zhang, C, Vago, F, Ren, Y, Jakata, J, Chiu, W, Serwer, P, Jiang, W.
登録日2014-08-12
公開日2014-10-15
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Capsid expansion mechanism of bacteriophage T7 revealed by multistate atomic models derived from cryo-EM reconstructions.
Proc.Natl.Acad.Sci.USA, 111, 2014

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