1R0B
| Aspartate Transcarbamylase (ATCase) of Escherichia coli: A New Crystalline R State Bound to PALA, or to Product Analogues Phosphate and Citrate | Descriptor: | Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CITRATE ANION, ... | Authors: | Huang, J, Lipscomb, W.N. | Deposit date: | 2003-09-19 | Release date: | 2004-06-08 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Aspartate Transcarbamylase (ATCase) of Escherichia coli: A New Crystalline R-State Bound to PALA, or to Product Analogues Citrate and Phosphate Biochemistry, 43, 2004
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1QKI
| X-RAY STRUCTURE OF HUMAN GLUCOSE 6-PHOSPHATE DEHYDROGENASE (VARIANT CANTON R459L) COMPLEXED WITH STRUCTURAL NADP+ | Descriptor: | GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE, GLYCEROL, GLYCOLIC ACID, ... | Authors: | Au, S.W.N, Gover, S, Lam, V.M.S, Adams, M.J. | Deposit date: | 1999-07-20 | Release date: | 2000-03-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Human Glucose-6-Phosphate Dehydrogenase: The Crystal Structure Reveals a Structural Nadp+ Molecule and Provides Insights Into Enzyme Deficiency Structure, 8, 2000
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3R9V
| Cocrystal Structure of Proteolytically Truncated Form of IpaD from Shigella flexneri Bound to Deoxycholate | Descriptor: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, GLYCEROL, Invasin ipaD | Authors: | Barta, M.L, Dickenson, N.E, Picking, W.L, Picking, W.D, Geisbrecht, B.V. | Deposit date: | 2011-03-26 | Release date: | 2011-12-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Identification of the bile salt binding site on IpaD from Shigella flexneri and the influence of ligand binding on IpaD structure. Proteins, 80, 2012
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3R1E
| Crystal structure of GC(8BrG)GCGGC duplex | Descriptor: | BROMIDE ION, CALCIUM ION, GLYCEROL, ... | Authors: | Kiliszek, A, Kierzek, R, Krzyzosiak, W.J, Rypniewski, W. | Deposit date: | 2011-03-10 | Release date: | 2011-06-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (0.972 Å) | Cite: | Crystal structures of CGG RNA repeats with implications for fragile X-associated tremor ataxia syndrome. Nucleic Acids Res., 39, 2011
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9C1A
| Crystal structure of GDP-bound human M-RAS protein in crystal form I | Descriptor: | GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Bester, S.M, Abrahamsen, R, Samora, L.R, Wu, W.-I, Mou, T.-C. | Deposit date: | 2024-05-28 | Release date: | 2024-09-11 | Last modified: | 2024-09-18 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Crystal structure of the GDP-bound human M-RAS protein in two crystal forms. Acta Crystallogr.,Sect.F, 80, 2024
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9GG1
| P301T type I tau filaments from human brain | Descriptor: | Isoform Tau-D of Microtubule-associated protein tau | Authors: | Schweighauser, M, Shi, Y, Murzin, A.G, Garringer, H.J, Vidal, R, Murrell, J.R, Erro, M.E, Seelaar, H, Ferrer, I, van Swieten, J.C, Ghetti, B, Scheres, S.H.W, Goedert, M. | Deposit date: | 2024-08-12 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.26 Å) | Cite: | Novel tau filament folds in individuals with MAPT mutations P301L and P301T. Biorxiv, 2024
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5M4Z
| Crystal structure of the complex of T.spiralis thymidylate synthase with N(4)-hydroxy-2'-deoxycytidine-5'-monophosphate, crystallized in the presence of N(5,10)-methylenetetrahydrofolate | Descriptor: | GLYCEROL, Thymidylate synthase, [(2~{R},3~{S},5~{R})-5-[(4~{E})-4-hydroxyimino-2-oxidanylidene-1,3-diazinan-1-yl]-3-oxidanyl-oxolan-2-yl]methyl dihydrogen phosphate | Authors: | Wilk, P, Maj, P, Jarmula, A, Dowiercial, A, Rode, W. | Deposit date: | 2016-10-19 | Release date: | 2017-12-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.179 Å) | Cite: | Molecular Mechanism of Thymidylate Synthase Inhibition by N 4 -Hydroxy-dCMP in View of Spectrophotometric and Crystallographic Studies. Int J Mol Sci, 22, 2021
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9C1B
| Crystal structure of GDP-bound human M-RAS protein in crystal form II | Descriptor: | DI(HYDROXYETHYL)ETHER, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Bester, S.M, Abrahamsen, R, Samora, L.R, Wu, W.-I, Mou, T.-C. | Deposit date: | 2024-05-28 | Release date: | 2024-09-11 | Last modified: | 2024-09-18 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Crystal structure of the GDP-bound human M-RAS protein in two crystal forms. Acta Crystallogr.,Sect.F, 80, 2024
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9GG0
| P301L tau filaments from human brain | Descriptor: | Isoform Tau-D of Microtubule-associated protein tau | Authors: | Schweighauser, M, Shi, Y, Murzin, A.G, Garringer, H.J, Vidal, R, Murrell, J.R, Erro, M.E, Seelaar, H, Ferrer, I, van Swieten, J.C, Ghetti, B, Scheres, S.H.W, Goedert, M. | Deposit date: | 2024-08-12 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.81 Å) | Cite: | Novel tau filament folds in individuals with MAPT mutations P301L and P301T. Biorxiv, 2024
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7NPT
| Cytosolic bridge of an intact ESX-5 inner membrane complex | Descriptor: | ESX-5 secretion system protein EccC5, ESX-5 secretion system protein EccD5 | Authors: | Fahrenkamp, D, Bunduc, C.M, Wald, J, Ummels, R, Bitter, W, Houben, E.N.G, Marlovits, T.C. | Deposit date: | 2021-02-28 | Release date: | 2021-05-26 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | Structure and dynamics of a mycobacterial type VII secretion system. Nature, 593, 2021
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7NPS
| Structure of the periplasmic assembly from the ESX-5 inner membrane complex, C1 model | Descriptor: | ESX-5 secretion system ATPase EccB5, Mycosin-5 | Authors: | Fahrenkamp, D, Bunduc, C.M, Wald, J, Ummels, R, Bitter, W, Houben, E.N.G, Marlovits, T.C. | Deposit date: | 2021-02-28 | Release date: | 2021-05-26 | Last modified: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (3.81 Å) | Cite: | Structure and dynamics of a mycobacterial type VII secretion system. Nature, 593, 2021
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5M70
| Crystal Structure of human RhoGAP mutated in its arginin finger (R85A) in complex with RhoA.GDP.AlF4- human | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rho GTPase-activating protein 1, ... | Authors: | Pellegrini, E, Bowler, M.W. | Deposit date: | 2016-10-26 | Release date: | 2017-05-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Assessing the Influence of Mutation on GTPase Transition States by Using X-ray Crystallography, (19) F NMR, and DFT Approaches. Angew. Chem. Int. Ed. Engl., 56, 2017
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9GG6
| P301T type II tau filaments from human brain | Descriptor: | Isoform Tau-F of Microtubule-associated protein tau | Authors: | Schweighauser, M, Shi, Y, Murzin, A.G, Garringer, H.J, Vidal, R, Murrell, J.R, Erro, M.E, Seelaar, H, Ferrer, I, van Swieten, J.C, Ghetti, B, Scheres, S.H.W, Goedert, M. | Deposit date: | 2024-08-13 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | Novel tau filament folds in individuals with MAPT mutations P301L and P301T. Biorxiv, 2024
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5M8N
| Crystal structure of human tyrosinase related protein 1 in complex with mimosine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lai, X, Soler-Lopez, M, Wichers, H.J, Dijkstra, B.W. | Deposit date: | 2016-10-29 | Release date: | 2017-07-12 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of Human Tyrosinase Related Protein 1 Reveals a Binuclear Zinc Active Site Important for Melanogenesis. Angew. Chem. Int. Ed. Engl., 56, 2017
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5MD9
| The structure of the mature HIV-1 CA hexameric lattice with curvature parameters: tilt=17, twist=6 | Descriptor: | Capsid protein p24 C-terminal domain, Capsid protein p24 N-terminal domain | Authors: | Mattei, S, Glass, B, Hagen, W.J.H, Kraeusslich, H.-G, Briggs, J.A.G. | Deposit date: | 2016-11-10 | Release date: | 2016-12-28 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (8 Å) | Cite: | The structure and flexibility of conical HIV-1 capsids determined within intact virions. Science, 354, 2016
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1GWZ
| CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THE PROTEIN TYROSINE PHOSPHATASE SHP-1 | Descriptor: | SHP-1 | Authors: | Yang, J, Liang, X, Niu, T, Meng, W, Zhao, Z, Zhou, G.W. | Deposit date: | 1998-08-22 | Release date: | 1999-08-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of the catalytic domain of protein-tyrosine phosphatase SHP-1. J.Biol.Chem., 273, 1998
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5MD7
| The structure of the mature HIV-1 CA hexameric lattice with curvature parameters: tilt=11, twist=-12 | Descriptor: | Capsid protein p24 | Authors: | Mattei, S, Glass, B, Hagen, W.J.H, Kraeusslich, H.-G, Briggs, J.A.G. | Deposit date: | 2016-11-10 | Release date: | 2016-12-28 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (8.4 Å) | Cite: | The structure and flexibility of conical HIV-1 capsids determined within intact virions. Science, 354, 2016
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5MD3
| The structure of the mature HIV-1 CA hexameric lattice with curvature parameters: tilt=11, twist=12 | Descriptor: | Capsid protein p24 | Authors: | Mattei, S, Glass, B, Hagen, W.J.H, Kraeusslich, H.-G, Briggs, J.A.G. | Deposit date: | 2016-11-10 | Release date: | 2016-12-28 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (8.5 Å) | Cite: | The structure and flexibility of conical HIV-1 capsids determined within intact virions. Science, 354, 2016
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5MDE
| The structure of the mature HIV-1 CA hexameric lattice with curvature parameters: tilt=23, twist=0 | Descriptor: | Capsid protein p24 C-terminal domain, Capsid protein p24 N-terminal domain | Authors: | Mattei, S, Glass, B, Hagen, W.J.H, Kraeusslich, H.-G, Briggs, J.A.G. | Deposit date: | 2016-11-10 | Release date: | 2016-12-28 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (8.4 Å) | Cite: | The structure and flexibility of conical HIV-1 capsids determined within intact virions. Science, 354, 2016
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2WIB
| Crystal Structures of the N-terminal Intracellular Domain of FeoB from Klebsiella Pneumoniae in GDP binding state | Descriptor: | FERROUS IRON TRANSPORT PROTEIN B, GUANOSINE-5'-DIPHOSPHATE | Authors: | Hung, K.-W, Chang, Y.-W, Chen, J.-H, Chen, Y.-C, Sun, Y.-J, Hsiao, C.-D, Huang, T.-H. | Deposit date: | 2009-05-09 | Release date: | 2010-05-19 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Structural Fold, Conservation and Fe(II) Binding of the Intracellular Domain of Prokaryote Feob. J.Struct.Biol., 170, 2010
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253L
| LYSOZYME | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME | Authors: | Kuroki, R, Shoichet, B, Weaver, L.H, Matthews, B.W. | Deposit date: | 1997-11-10 | Release date: | 1998-01-28 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A relationship between protein stability and protein function. Proc.Natl.Acad.Sci.USA, 92, 1995
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2WIA
| Crystal Structures of the N-terminal Intracellular Domain of FeoB from Klebsiella Pneumoniae in Apo Form | Descriptor: | FERROUS IRON TRANSPORT PROTEIN B, MAGNESIUM ION | Authors: | Hung, K.-W, Chang, Y.-W, Chen, J.-H, Chen, Y.-C, Sun, Y.-J, Hsiao, C.-D, Huang, T.-H. | Deposit date: | 2009-05-09 | Release date: | 2010-05-19 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structural Fold, Conservation and Fe(II) Binding of the Intracellular Domain of Prokaryote Feob. J.Struct.Biol., 170, 2010
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8QAV
| Medicago truncatula HISN5 (IGPD) in complex with MN and IG2 | Descriptor: | (2S,3S)-2,3-dihydroxy-3-(1H-imidazol-5-yl)propyl dihydrogen phosphate, Imidazoleglycerol-phosphate dehydratase, MANGANESE (II) ION | Authors: | Witek, W, Ruszkowski, M. | Deposit date: | 2023-08-23 | Release date: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (2.23 Å) | Cite: | Targeting imidazole-glycerol phosphate dehydratase in plants: novel approach for structural and functional studies, and inhibitor blueprinting. Front Plant Sci, 15, 2024
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1H47
| Structures of MECP synthase in complex with (i) CMP and (ii) CMP and product | Descriptor: | 2C-METHYL-D-ERYTHRITOL-2,4-CYCLODIPHOSPHATE SYNTHASE, CYTIDINE-5'-MONOPHOSPHATE, GERANYL DIPHOSPHATE, ... | Authors: | Kemp, L.E, Alphey, M.S, Bond, C.S, Hunter, W.N. | Deposit date: | 2003-02-24 | Release date: | 2004-10-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | The Identification of Isoprenoids that Bind in the Intersubunit Cavity of Escherichia Coli 2C-Methyl-D-Erythritol-2,4-Cyclodiphosphate Synthase by Complementary Biophysical Methods Acta Crystallogr.,Sect.D, 61, 2005
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5MDA
| The structure of the mature HIV-1 CA hexameric lattice with curvature parameters: tilt=17, twist=0 | Descriptor: | Gag protein | Authors: | Mattei, S, Glass, B, Hagen, W.J.H, Kraeusslich, H.-G, Briggs, J.A.G. | Deposit date: | 2016-11-10 | Release date: | 2016-12-28 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (8.4 Å) | Cite: | The structure and flexibility of conical HIV-1 capsids determined within intact virions. Science, 354, 2016
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