7H0Y
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![BU of 7h0y by Molmil](/molmil-images/mine/7h0y) | Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0013258-001 | 分子名称: | 4-{[(1S)-1-(1,1-dioxo-1,2,3,4-tetrahydro-1lambda~6~-benzothiopyran-7-yl)-2-methylpropyl]amino}-N-(1-methylazetidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide, Papain-like protease nsp3 | 著者 | Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F. | 登録日 | 2024-01-23 | 公開日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre To Be Published
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7H0S
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![BU of 7h0s by Molmil](/molmil-images/mine/7h0s) | Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0013769-001 | 分子名称: | 4-{[(1S)-1-(2-acetamido-1,3-benzothiazol-6-yl)-2-methylpropyl]amino}-N-ethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide, Papain-like protease nsp3 | 著者 | Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F. | 登録日 | 2024-01-23 | 公開日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | 主引用文献 | Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre To Be Published
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2BNM
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7H1C
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![BU of 7h1c by Molmil](/molmil-images/mine/7h1c) | Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0014597-001 | 分子名称: | 7-[(1S)-1-{[(5R,8S)-10-acetyl-6,7,8,9-tetrahydro-5H-5,8-epiminocyclohepta[d]pyrimidin-4-yl]amino}-2-methylpropyl]-3,4-dihydro-1lambda~6~-benzothiopyran-1,1(2H)-dione, Papain-like protease nsp3 | 著者 | Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F. | 登録日 | 2024-01-23 | 公開日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre To Be Published
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3VDA
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![BU of 3vda by Molmil](/molmil-images/mine/3vda) | E. coli (lacZ) beta-galactosidase (N460T) | 分子名称: | Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... | 著者 | Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E. | 登録日 | 2012-01-04 | 公開日 | 2012-04-11 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability. Arch.Biochem.Biophys., 521, 2012
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1IJD
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![BU of 1ijd by Molmil](/molmil-images/mine/1ijd) | Crystallographic Structure of the LH3 Complex from Rhodopseudomonas acidophila strain 7050 | 分子名称: | BACTERIOCHLOROPHYLL A, LIGHT-HARVESTING PROTEIN B-800/820, ALPHA CHAIN, ... | 著者 | McLuskey, K, Prince, S.M, Cogdell, R.J, Isaacs, N.W. | 登録日 | 2001-04-25 | 公開日 | 2001-10-17 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The crystallographic structure of the B800-820 LH3 light-harvesting complex from the purple bacteria Rhodopseudomonas acidophila strain 7050. Biochemistry, 40, 2001
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7GZX
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![BU of 7gzx by Molmil](/molmil-images/mine/7gzx) | Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0011176-001 | 分子名称: | 7-[(1S)-2-methyl-1-{[(6M)-6-{5-[(methylamino)methyl]furan-3-yl}-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}propyl]-3,4-dihydro-1lambda~6~-benzothiopyran-1,1(2H)-dione, Papain-like protease nsp3 | 著者 | Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F. | 登録日 | 2024-01-23 | 公開日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre To Be Published
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4WPZ
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![BU of 4wpz by Molmil](/molmil-images/mine/4wpz) | Crystal structure of cytochrome P450 CYP107W1 from Streptomyces avermitilis | 分子名称: | Cytochrome P450, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Kang, L.W, Kim, D.H, Pham, T.V, Han, S.H. | 登録日 | 2014-10-21 | 公開日 | 2015-04-22 | 最終更新日 | 2015-04-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Functional characterization of CYP107W1 from Streptomyces avermitilis and biosynthesis of macrolide oligomycin A. Arch.Biochem.Biophys., 575, 2015
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7H0H
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![BU of 7h0h by Molmil](/molmil-images/mine/7h0h) | Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0011204-001 | 分子名称: | N-ethyl-4-{[(1S)-2-methyl-1-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)propyl]amino}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide, Papain-like protease nsp3 | 著者 | Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F. | 登録日 | 2024-01-23 | 公開日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | 主引用文献 | Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre To Be Published
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7H14
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![BU of 7h14 by Molmil](/molmil-images/mine/7h14) | Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0013383-001 | 分子名称: | 7-[(1R)-2-methyl-1-{[(6M)-6-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}propyl]-3,4-dihydro-1lambda~6~-benzothiopyran-1,1(2H)-dione, Papain-like protease nsp3 | 著者 | Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F. | 登録日 | 2024-01-23 | 公開日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre To Be Published
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2FOL
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![BU of 2fol by Molmil](/molmil-images/mine/2fol) | Crystal structure of human RAB1A in complex with GDP | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-1A, ... | 著者 | Wang, J, Tempel, W, Shen, Y, Shen, L, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | 登録日 | 2006-01-13 | 公開日 | 2006-01-31 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.631 Å) | 主引用文献 | Crystal structure of human RAB1A in complex with GDP To be Published
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4WLJ
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![BU of 4wlj by Molmil](/molmil-images/mine/4wlj) | High resolution crystal structure of human kynurenine aminotransferase-I in complex with aminooxyacetate | 分子名称: | 4'-DEOXY-4'-ACETYLYAMINO-PYRIDOXAL-5'-PHOSPHATE, Kynurenine--oxoglutarate transaminase 1 | 著者 | Nadvi, N.A, Salam, N.K, Park, J, Akladios, F.N, Kapoor, V, Collyer, C.A, Gorrell, M.D, Church, W.B. | 登録日 | 2014-10-07 | 公開日 | 2014-12-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | High resolution crystal structures of human kynurenine aminotransferase-I bound to PLP cofactor, and in complex with aminooxyacetate. Protein Sci., 26, 2017
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7H1F
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![BU of 7h1f by Molmil](/molmil-images/mine/7h1f) | Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0015381-001 | 分子名称: | N-[(1R)-1-(4-methoxyphenyl)-2-(1H-tetrazol-5-yl)ethyl]-7H-pyrrolo[2,3-d]pyrimidine-4-carboxamide, Papain-like protease nsp3 | 著者 | Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F. | 登録日 | 2024-01-23 | 公開日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre To Be Published
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4WMJ
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4WOZ
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![BU of 4woz by Molmil](/molmil-images/mine/4woz) | Crystal Structures of CdNal from Clostridium difficile in complex with mannosamine | 分子名称: | 2-(ACETYLAMINO)-2-DEOXY-D-MANNOSE, N-acetylneuraminate lyase | 著者 | Liu, W.D, Guo, R.T, Cui, Y.F, Chen, X, Wu, Q.Q, Zhu, D.M. | 登録日 | 2014-10-17 | 公開日 | 2015-10-21 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Crystal Structures of CdNal from Clostridium difficile in complex with mannosamine to be published
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3LXD
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![BU of 3lxd by Molmil](/molmil-images/mine/3lxd) | Crystal Structure of Ferredoxin Reductase ArR from Novosphingobium aromaticivorans | 分子名称: | FAD-dependent pyridine nucleotide-disulphide oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Yang, W, Bell, S.G, Wang, H, Bartlam, M, Wong, L.L, Rao, Z. | 登録日 | 2010-02-25 | 公開日 | 2010-06-23 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular characterization of a class I P450 electron transfer system from Novosphingobium aromaticivorans DSM12444 J.Biol.Chem., 285, 2010
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5KEH
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5KF3
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2ID5
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![BU of 2id5 by Molmil](/molmil-images/mine/2id5) | Crystal Structure of the Lingo-1 Ectodomain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Leucine rich repeat neuronal 6A, ... | 著者 | Mosyak, L, Wood, A, Dwyer, B, Johnson, M, Stahl, M.L, Somers, W.S. | 登録日 | 2006-09-14 | 公開日 | 2006-09-26 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.698 Å) | 主引用文献 | The structure of the Lingo-1 ectodomain, a module implicated in central nervous system repair inhibition. J.Biol.Chem., 281, 2006
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4WH4
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![BU of 4wh4 by Molmil](/molmil-images/mine/4wh4) | Protein GB1 Quadruple Mutant I6H/N8H/K28H/Q32H | 分子名称: | GLYCEROL, Immunoglobulin G-binding protein G, SULFATE ION | 著者 | Cunningham, T.C, Horne, W.S, Saxena, S. | 登録日 | 2014-09-19 | 公開日 | 2015-08-05 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The double-histidine Cu2+-binding motif: a highly rigid, site-specific spin probe for electron spin resonance distance measurements. Angew.Chem.Int.Ed.Engl., 54, 2015
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4WLR
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![BU of 4wlr by Molmil](/molmil-images/mine/4wlr) | Crystal Structure of mUCH37-hRPN13 CTD-hUb complex | 分子名称: | Polyubiquitin-B, Proteasomal ubiquitin receptor ADRM1, Ubiquitin carboxyl-terminal hydrolase isozyme L5 | 著者 | Hemmis, C.W, Hill, C.P, VanderLinden, R, Whitby, F.G. | 登録日 | 2014-10-07 | 公開日 | 2015-03-04 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | Structural Basis for the Activation and Inhibition of the UCH37 Deubiquitylase. Mol.Cell, 57, 2015
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7JMA
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4WK0
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![BU of 4wk0 by Molmil](/molmil-images/mine/4wk0) | Metal Ion and Ligand Binding of Integrin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ARG-GLY-ASP, ... | 著者 | Xia, W, Springer, T.A. | 登録日 | 2014-10-01 | 公開日 | 2014-12-03 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Metal ion and ligand binding of integrin alpha 5 beta 1. Proc.Natl.Acad.Sci.USA, 111, 2014
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4WP0
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![BU of 4wp0 by Molmil](/molmil-images/mine/4wp0) | Crystal structure of human kynurenine aminotransferase-I with a C-terminal V5-hexahistidine tag | 分子名称: | Kynurenine--oxoglutarate transaminase 1 | 著者 | Nadvi, N.A, Salam, N.K, Park, J, Akladios, F.N, Kapoor, V, Collyer, C.A, Gorrell, M.D, Church, W.B. | 登録日 | 2014-10-17 | 公開日 | 2014-11-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of human kynurenine aminotransferase-I in a novel space group To be published
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4H9P
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![BU of 4h9p by Molmil](/molmil-images/mine/4h9p) | Complex structure 3 of DAXX/H3.3(sub5,G90A)/H4 | 分子名称: | Death domain-associated protein 6, Histone H3.3, Histone H4, ... | 著者 | Elsasser, S.J, Huang, H, Lewis, P.W, Chin, J.W, Allis, D.C, Patel, D.J. | 登録日 | 2012-09-24 | 公開日 | 2012-10-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.198 Å) | 主引用文献 | DAXX chaperone envelops an H3.3/H4 dimer dictating H3.3-specific read out To be Published
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