8VJC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8vjc by Molmil](/molmil-images/mine/8vjc) | Cryo-EM structure of short form insulin receptor (IR-A) with three IGF2 bound, asymmetric conformation. | 分子名称: | Insulin-like growth factor II, Isoform Short of Insulin receptor | 著者 | An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E. | 登録日 | 2024-01-06 | 公開日 | 2024-03-27 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Activation of the insulin receptor by insulin-like growth factor 2. Nat Commun, 15, 2024
|
|
9F9L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9f9l by Molmil](/molmil-images/mine/9f9l) | Crystal structure of MUS81-EME1 bound by compound 16. | 分子名称: | 2-[2-[4-(cyanomethyl)phenyl]phenyl]-5-oxidanyl-6-oxidanylidene-1H-pyrimidine-4-carboxylic acid, Crossover junction endonuclease EME1, Crossover junction endonuclease MUS81, ... | 著者 | Collie, G.W. | 登録日 | 2024-05-07 | 公開日 | 2024-07-03 | 最終更新日 | 2024-07-31 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Fragment-Based Discovery of Novel MUS81 Inhibitors. Acs Med.Chem.Lett., 15, 2024
|
|
8VJ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8vj0 by Molmil](/molmil-images/mine/8vj0) | Neutron Structure of Oxidized Trp161Phe MnSOD | 分子名称: | MANGANESE (II) ION, Superoxide dismutase [Mn], mitochondrial | 著者 | Azadmanesh, J, Slobodnik, K, Struble, L.R, Lutz, W.E, Weiss, K.L, Myles, D.A.A, Kroll, T, Borgstahl, G.E.O. | 登録日 | 2024-01-05 | 公開日 | 2024-07-31 | 実験手法 | NEUTRON DIFFRACTION (2.3 Å) | 主引用文献 | Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition. Biorxiv, 2024
|
|
8YF8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8yf8 by Molmil](/molmil-images/mine/8yf8) | |
8XAT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8xat by Molmil](/molmil-images/mine/8xat) | |
8YHP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8yhp by Molmil](/molmil-images/mine/8yhp) | Structure of the PGK1 from Biortus. | 分子名称: | 1,2-ETHANEDIOL, Phosphoglycerate kinase 1 | 著者 | Wang, F, Cheng, W, Lv, Z, Ju, C, Wang, J. | 登録日 | 2024-02-28 | 公開日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure of the PGK1 from Biortus. To Be Published
|
|
8ZH5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8zh5 by Molmil](/molmil-images/mine/8zh5) | |
8W6K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8w6k by Molmil](/molmil-images/mine/8w6k) | in situ room temperature Laue crystallography | 分子名称: | Lysozyme C | 著者 | Wang, Z.J, Wang, S.S, Pan, Q.Y, Yu, L, Su, Z.H, Yang, T.Y, Wang, Y.Z, Zhang, W.Z, Hao, Q, Gao, X.Y. | 登録日 | 2023-08-29 | 公開日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | BL03HB: Laue crystallography beamline at SSRF To Be Published
|
|
8XEY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8xey by Molmil](/molmil-images/mine/8xey) | The Crystal Structure of C-terminal kinase domain of RSK2 from Biortus | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Ribosomal protein S6 kinase alpha-3 | 著者 | Wang, F, Cheng, W, Lv, Z, Meng, Q, Zhang, B. | 登録日 | 2023-12-13 | 公開日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | The Crystal Structure of C-terminal kinase domain of RSK2 from Biortus To Be Published
|
|
8YY8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8yy8 by Molmil](/molmil-images/mine/8yy8) | Fzd7 -Gs complex | 分子名称: | Frizzled-7, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Chen, B, Xu, L, Han, G.W, Xu, F. | 登録日 | 2024-04-03 | 公開日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | 主引用文献 | Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric G s . Cell Res., 31, 2021
|
|
8Y9V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8y9v by Molmil](/molmil-images/mine/8y9v) | ZIKV NS2B/NS3 protease | 分子名称: | DAR-LYS-ORN-ARG, Serine protease NS3, Serine protease subunit NS2B | 著者 | Zhang, C.Y, Xu, Q, Wang, W.W, Zhou, H, Wang, Q.S. | 登録日 | 2024-02-07 | 公開日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystallographic data collection using a multilayer monochromator on an undulator beamline at SSRF To Be Published
|
|
9BU1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9bu1 by Molmil](/molmil-images/mine/9bu1) | |
8VCI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8vci by Molmil](/molmil-images/mine/8vci) | SARS-CoV-2 Frameshift Stimulatory Element with Upstream Multibranch Loop | 分子名称: | Frameshift Stimulatory Element with Upstream Multi-branch Loop | 著者 | Peterson, J.M, Becker, S.T, O'Leary, C.A, Juneja, P, Yang, Y, Moss, W.N. | 登録日 | 2023-12-14 | 公開日 | 2024-01-17 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | 主引用文献 | Structure of the SARS-CoV-2 Frameshift Stimulatory Element with an Upstream Multibranch Loop. Biochemistry, 63, 2024
|
|
8VSI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8vsi by Molmil](/molmil-images/mine/8vsi) | Mechanistic Insights Revealed by YbtPQ in the Occluded State | 分子名称: | ABC transporter ATP-binding protein, ADP ORTHOVANADATE, MAGNESIUM ION, ... | 著者 | Hu, W, Parkinson, C, Zheng, H. | 登録日 | 2024-01-24 | 公開日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Mechanistic Insights Revealed by YbtPQ in the Occluded State. Biomolecules, 14, 2024
|
|
9CA1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9ca1 by Molmil](/molmil-images/mine/9ca1) | Human TOP3B-TDRD3 core complex in DNA religation state | 分子名称: | DNA (5'-D(*AP*TP*T)-3'), DNA (5'-D(P*TP*AP*CP*TP*AP*AP*A)-3'), DNA topoisomerase 3-beta-1, ... | 著者 | Yang, X, Chen, X, Yang, W, Pommier, Y. | 登録日 | 2024-06-16 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | Structural Insights into human Topoisomerase 3-beta DNA and RNA catalytic cycles and topo-gate dynamics To Be Published
|
|
8XB3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8xb3 by Molmil](/molmil-images/mine/8xb3) | |
9AUK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9auk by Molmil](/molmil-images/mine/9auk) | Structure of SARS-CoV-2 Mpro mutant (A173V) in complex with Nirmatrelvir (PF-07321332) | 分子名称: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 | 著者 | Gajiwala, K.S, Greasley, S.E, Ferre, R.A, Liu, W, Stewart, A.E. | 登録日 | 2024-02-29 | 公開日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | In vitro selection and analysis of SARS-CoV-2 nirmatrelvir resistance mutations contributing to clinical virus resistance surveillance. Sci Adv, 10, 2024
|
|
9EOF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9eof by Molmil](/molmil-images/mine/9eof) | Structure of the human INTS5/8/10/15 subcomplex | 分子名称: | Integrator complex subunit 10, Integrator complex subunit 15, Integrator complex subunit 5, ... | 著者 | Razew, M, Galej, W.P. | 登録日 | 2024-03-14 | 公開日 | 2024-06-12 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | 主引用文献 | Structural basis of the Integrator complex assembly and association with transcription factors. Mol.Cell, 84, 2024
|
|
8W1S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8w1s by Molmil](/molmil-images/mine/8w1s) | Cryo-EM structure of BTV pre-core | 分子名称: | Core protein VP3, RNA-directed RNA polymerase | 著者 | Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H. | 登録日 | 2024-02-17 | 公開日 | 2024-04-24 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells. Cell, 187, 2024
|
|
8WA3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8wa3 by Molmil](/molmil-images/mine/8wa3) | Cryo-EM structure of peptide free and Gs-coupled GIPR | 分子名称: | Gastric inhibitory polypeptide receptor,Fusion protein, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1,O-antigen polymerase, ... | 著者 | Cong, Z.T, Zhao, F.H, Li, Y, Luo, G, Zhou, Q.T, Yang, D.H, Wang, M.W. | 登録日 | 2023-09-06 | 公開日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | 主引用文献 | Molecular features of the ligand-free GLP-1R, GCGR and GIPR in complex with G s proteins. Cell Discov, 10, 2024
|
|
8XLD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8xld by Molmil](/molmil-images/mine/8xld) | Structure of the GFP:GFP-nanobody complex from Biortus. | 分子名称: | 1,2-ETHANEDIOL, Nanobody(Staygold-S2G10)-Nanobody(Staygold-S4F1), ZINC ION, ... | 著者 | Wang, F, Cheng, W, Yuan, Z, Lin, D, Bao, C. | 登録日 | 2023-12-25 | 公開日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of the GFP:GFP-nanobody complex from Biortus. To Be Published
|
|
8XOY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8xoy by Molmil](/molmil-images/mine/8xoy) | The Crystal Structure of PTP1B from Biortus. | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | 著者 | Wang, F, Cheng, W, Lv, Z, Meng, Q, Li, J. | 登録日 | 2024-01-02 | 公開日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | The Crystal Structure of PTP1B from Biortus. To Be Published
|
|
8YGW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ygw by Molmil](/molmil-images/mine/8ygw) | The Crystal Structure of MAPK11 from Biortus | 分子名称: | 1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-[4-(2-MORPHOLIN-4-YL-ETHOXY)-NAPHTHALEN-1-YL]-UREA, Mitogen-activated protein kinase 11 | 著者 | Wang, F, Cheng, W, Yuan, Z, Lin, D, Guo, S. | 登録日 | 2024-02-27 | 公開日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.301 Å) | 主引用文献 | The Crystal Structure of MAPK11 from Biortus. To Be Published
|
|
8YKW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ykw by Molmil](/molmil-images/mine/8ykw) | Cryo-EM structure of succinate receptor SUCR1 bound to succinic acid | 分子名称: | Antibody fragment ScFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Li, C, Liu, H, Li, J, Zhu, H, Fu, W, Xu, H.E. | 登録日 | 2024-03-05 | 公開日 | 2024-05-29 | 最終更新日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | 主引用文献 | Molecular basis of ligand recognition and activation of the human succinate receptor SUCR1. Cell Res., 34, 2024
|
|
8VJ8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8vj8 by Molmil](/molmil-images/mine/8vj8) | X-ray Counterpart to Neutron Structure of Reduced Trp161Phe MnSOD | 分子名称: | MANGANESE (II) ION, PHOSPHATE ION, POTASSIUM ION, ... | 著者 | Azadmanesh, J, Slobodnik, K, Struble, L.R, Lutz, W.E, Weiss, K.L, Myles, D.A.A, Kroll, T, Borgstahl, G.E.O. | 登録日 | 2024-01-05 | 公開日 | 2024-07-31 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition. Biorxiv, 2024
|
|