8VJC
 
 | | Cryo-EM structure of short form insulin receptor (IR-A) with three IGF2 bound, asymmetric conformation. | | 分子名称: | Insulin-like growth factor II, Isoform Short of Insulin receptor | | 著者 | An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E. | | 登録日 | 2024-01-06 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Activation of the insulin receptor by insulin-like growth factor 2.
Nat Commun, 15, 2024
|
|
9F9L
 | | Crystal structure of MUS81-EME1 bound by compound 16. | | 分子名称: | 2-[2-[4-(cyanomethyl)phenyl]phenyl]-5-oxidanyl-6-oxidanylidene-1H-pyrimidine-4-carboxylic acid, Crossover junction endonuclease EME1, Crossover junction endonuclease MUS81, ... | | 著者 | Collie, G.W. | | 登録日 | 2024-05-07 | | 公開日 | 2024-07-03 | | 最終更新日 | 2024-07-31 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Fragment-Based Discovery of Novel MUS81 Inhibitors.
Acs Med.Chem.Lett., 15, 2024
|
|
8VJ0
 | | Neutron Structure of Oxidized Trp161Phe MnSOD | | 分子名称: | MANGANESE (II) ION, Superoxide dismutase [Mn], mitochondrial | | 著者 | Azadmanesh, J, Slobodnik, K, Struble, L.R, Lutz, W.E, Weiss, K.L, Myles, D.A.A, Kroll, T, Borgstahl, G.E.O. | | 登録日 | 2024-01-05 | | 公開日 | 2024-07-31 | | 実験手法 | NEUTRON DIFFRACTION (2.3 Å) | | 主引用文献 | Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition.
Biorxiv, 2024
|
|
8YF8
 | |
8XAT
 | |
8YHP
 | | Structure of the PGK1 from Biortus. | | 分子名称: | 1,2-ETHANEDIOL, Phosphoglycerate kinase 1 | | 著者 | Wang, F, Cheng, W, Lv, Z, Ju, C, Wang, J. | | 登録日 | 2024-02-28 | | 公開日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structure of the PGK1 from Biortus.
To Be Published
|
|
8ZH5
 | |
8W6K
 | | in situ room temperature Laue crystallography | | 分子名称: | Lysozyme C | | 著者 | Wang, Z.J, Wang, S.S, Pan, Q.Y, Yu, L, Su, Z.H, Yang, T.Y, Wang, Y.Z, Zhang, W.Z, Hao, Q, Gao, X.Y. | | 登録日 | 2023-08-29 | | 公開日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | BL03HB: Laue crystallography beamline at SSRF
To Be Published
|
|
8XEY
 | | The Crystal Structure of C-terminal kinase domain of RSK2 from Biortus | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Ribosomal protein S6 kinase alpha-3 | | 著者 | Wang, F, Cheng, W, Lv, Z, Meng, Q, Zhang, B. | | 登録日 | 2023-12-13 | | 公開日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | The Crystal Structure of C-terminal kinase domain of RSK2 from Biortus
To Be Published
|
|
8YY8
 | | Fzd7 -Gs complex | | 分子名称: | Frizzled-7, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Chen, B, Xu, L, Han, G.W, Xu, F. | | 登録日 | 2024-04-03 | | 公開日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | | 主引用文献 | Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric G s .
Cell Res., 31, 2021
|
|
8Y9V
 | | ZIKV NS2B/NS3 protease | | 分子名称: | DAR-LYS-ORN-ARG, Serine protease NS3, Serine protease subunit NS2B | | 著者 | Zhang, C.Y, Xu, Q, Wang, W.W, Zhou, H, Wang, Q.S. | | 登録日 | 2024-02-07 | | 公開日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystallographic data collection using a multilayer monochromator on an undulator beamline at SSRF
To Be Published
|
|
9BU1
 | |
8VCI
 | | SARS-CoV-2 Frameshift Stimulatory Element with Upstream Multibranch Loop | | 分子名称: | Frameshift Stimulatory Element with Upstream Multi-branch Loop | | 著者 | Peterson, J.M, Becker, S.T, O'Leary, C.A, Juneja, P, Yang, Y, Moss, W.N. | | 登録日 | 2023-12-14 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | | 主引用文献 | Structure of the SARS-CoV-2 Frameshift Stimulatory Element with an Upstream Multibranch Loop.
Biochemistry, 63, 2024
|
|
8VSI
 | | Mechanistic Insights Revealed by YbtPQ in the Occluded State | | 分子名称: | ABC transporter ATP-binding protein, ADP ORTHOVANADATE, MAGNESIUM ION, ... | | 著者 | Hu, W, Parkinson, C, Zheng, H. | | 登録日 | 2024-01-24 | | 公開日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Mechanistic Insights Revealed by YbtPQ in the Occluded State.
Biomolecules, 14, 2024
|
|
9CA1
 | | Human TOP3B-TDRD3 core complex in DNA religation state | | 分子名称: | DNA (5'-D(*AP*TP*T)-3'), DNA (5'-D(P*TP*AP*CP*TP*AP*AP*A)-3'), DNA topoisomerase 3-beta-1, ... | | 著者 | Yang, X, Chen, X, Yang, W, Pommier, Y. | | 登録日 | 2024-06-16 | | 公開日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | | 主引用文献 | Structural Insights into human Topoisomerase 3-beta DNA and RNA catalytic cycles and topo-gate dynamics
To Be Published
|
|
8XB3
 | |
9AUK
 | | Structure of SARS-CoV-2 Mpro mutant (A173V) in complex with Nirmatrelvir (PF-07321332) | | 分子名称: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 | | 著者 | Gajiwala, K.S, Greasley, S.E, Ferre, R.A, Liu, W, Stewart, A.E. | | 登録日 | 2024-02-29 | | 公開日 | 2024-08-07 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | In vitro selection and analysis of SARS-CoV-2 nirmatrelvir resistance mutations contributing to clinical virus resistance surveillance.
Sci Adv, 10, 2024
|
|
9EOF
 | | Structure of the human INTS5/8/10/15 subcomplex | | 分子名称: | Integrator complex subunit 10, Integrator complex subunit 15, Integrator complex subunit 5, ... | | 著者 | Razew, M, Galej, W.P. | | 登録日 | 2024-03-14 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | | 主引用文献 | Structural basis of the Integrator complex assembly and association with transcription factors.
Mol.Cell, 84, 2024
|
|
8W1S
 | | Cryo-EM structure of BTV pre-core | | 分子名称: | Core protein VP3, RNA-directed RNA polymerase | | 著者 | Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H. | | 登録日 | 2024-02-17 | | 公開日 | 2024-04-24 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells.
Cell, 187, 2024
|
|
8WA3
 | | Cryo-EM structure of peptide free and Gs-coupled GIPR | | 分子名称: | Gastric inhibitory polypeptide receptor,Fusion protein, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1,O-antigen polymerase, ... | | 著者 | Cong, Z.T, Zhao, F.H, Li, Y, Luo, G, Zhou, Q.T, Yang, D.H, Wang, M.W. | | 登録日 | 2023-09-06 | | 公開日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | | 主引用文献 | Molecular features of the ligand-free GLP-1R, GCGR and GIPR in complex with G s proteins.
Cell Discov, 10, 2024
|
|
8XLD
 | | Structure of the GFP:GFP-nanobody complex from Biortus. | | 分子名称: | 1,2-ETHANEDIOL, Nanobody(Staygold-S2G10)-Nanobody(Staygold-S4F1), ZINC ION, ... | | 著者 | Wang, F, Cheng, W, Yuan, Z, Lin, D, Bao, C. | | 登録日 | 2023-12-25 | | 公開日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure of the GFP:GFP-nanobody complex from Biortus.
To Be Published
|
|
8XOY
 | | The Crystal Structure of PTP1B from Biortus. | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | | 著者 | Wang, F, Cheng, W, Lv, Z, Meng, Q, Li, J. | | 登録日 | 2024-01-02 | | 公開日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | The Crystal Structure of PTP1B from Biortus.
To Be Published
|
|
8YGW
 | | The Crystal Structure of MAPK11 from Biortus | | 分子名称: | 1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-[4-(2-MORPHOLIN-4-YL-ETHOXY)-NAPHTHALEN-1-YL]-UREA, Mitogen-activated protein kinase 11 | | 著者 | Wang, F, Cheng, W, Yuan, Z, Lin, D, Guo, S. | | 登録日 | 2024-02-27 | | 公開日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.301 Å) | | 主引用文献 | The Crystal Structure of MAPK11 from Biortus.
To Be Published
|
|
8YKW
 | | Cryo-EM structure of succinate receptor SUCR1 bound to succinic acid | | 分子名称: | Antibody fragment ScFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Li, C, Liu, H, Li, J, Zhu, H, Fu, W, Xu, H.E. | | 登録日 | 2024-03-05 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-08-14 | | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | | 主引用文献 | Molecular basis of ligand recognition and activation of the human succinate receptor SUCR1.
Cell Res., 34, 2024
|
|
8VJ8
 | | X-ray Counterpart to Neutron Structure of Reduced Trp161Phe MnSOD | | 分子名称: | MANGANESE (II) ION, PHOSPHATE ION, POTASSIUM ION, ... | | 著者 | Azadmanesh, J, Slobodnik, K, Struble, L.R, Lutz, W.E, Weiss, K.L, Myles, D.A.A, Kroll, T, Borgstahl, G.E.O. | | 登録日 | 2024-01-05 | | 公開日 | 2024-07-31 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition.
Biorxiv, 2024
|
|
