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PDB: 73 件

2QZ9
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crystal structure of aspartate semialdehyde dehydrogenase II from vibrio cholerae
分子名称: Aspartate-semialdehyde dehydrogenase
著者Viola, R.E, Liu, X, Ohren, J.F, Faehnle, C.R.
登録日2007-08-16
公開日2008-04-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structure of a redundant enzyme: a second isoform of aspartate beta-semialdehyde dehydrogenase in Vibrio cholerae.
Acta Crystallogr.,Sect.D, 64, 2008
2R00
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crystal structure of aspartate semialdehyde dehydrogenase II complexed with ASA from vibrio cholerae
分子名称: 2,2'-oxydiacetic acid, Aspartate-semialdehyde dehydrogenase
著者Viola, R.E, Liu, X, Ohren, J.F, Faehnle, C.R.
登録日2007-08-17
公開日2008-04-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献The structure of a redundant enzyme: a second isoform of aspartate beta-semialdehyde dehydrogenase in Vibrio cholerae.
Acta Crystallogr.,Sect.D, 64, 2008
2J9N
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Robotically harvested Trypsin complexed with Benzamidine containing polypeptide mediated crystal contacts
分子名称: BENZAMIDINE, CALCIUM ION, CATIONIC TRYPSIN, ...
著者Viola, R, Carman, P, Walsh, J, Miller, E, Benning, M, Frankel, D, McPherson, A, Cudney, R, Rupp, B.
登録日2006-11-14
公開日2007-04-03
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Operator Assisted Harvesting of Protein Crystals Using a Universal Micromanipulation Robot.
J.Appl.Crystallogr., 40, 2007
1TB4
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Crystal Structure of Aspartate-Semialdehyde Dehydrogenase From Haemophilus influenzae with a Bound Periodate
分子名称: Aspartate-semialdehyde dehydrogenase, PERIODATE
著者Viola, R.E.
登録日2004-05-19
公開日2004-12-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural basis for discrimination between oxyanion substrates or inhibitors in aspartate-beta-semialdehyde dehydrogenase.
Acta Crystallogr.,Sect.D, 60, 2004
1TA4
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Crystal Structure Of Aspartate-Semialdehyde Dehydrogenase From Haemophilus Influenzae with a Bound Arsenate
分子名称: ARSENATE, Aspartate-semialdehyde dehydrogenase
著者Viola, R.E.
登録日2004-05-19
公開日2004-12-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Structural basis for discrimination between oxyanion substrates or inhibitors in aspartate-beta-semialdehyde dehydrogenase.
Acta Crystallogr.,Sect.D, 60, 2004
1IE3
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CRYSTAL STRUCTURE OF R153C E. COLI MALATE DEHYDROGENASE
分子名称: MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PYRUVIC ACID
著者Bell, J.K, Yennawar, H.P, Wright, S.K, Thompson, J.R, Viola, R.E, Banaszak, L.J.
登録日2001-04-05
公開日2001-09-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Analyses of a Malate Dehydrogenase with a Variable Active Site
J.Biol.Chem., 276, 2001
1IB6
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CRYSTAL STRUCTURE OF R153C E. COLI MALATE DEHYDROGENASE
分子名称: MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION
著者Bell, J.K, Yennawar, H.P, Wright, S.K, Thompson, J.R, Viola, R.E, Banaszak, L.J.
登録日2001-03-27
公開日2001-09-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Analyses of a Malate Dehydrogenase with a Variable Active Site
J.Biol.Chem., 276, 2001
3HSK
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Crystal Structure of Aspartate Semialdehyde Dehydrogenase with NADP from Candida albicans
分子名称: Aspartate-semialdehyde dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Arachea, B.T, Pavlovsky, A, Liu, X, Viola, R.E.
登録日2009-06-10
公開日2010-02-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Expansion of the aspartate beta-semialdehyde dehydrogenase family: the first structure of a fungal ortholog.
Acta Crystallogr.,Sect.D, 66, 2010
5JW6
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Cystal structure of aspartate semialdehyde dehydrogenase from Aspergillus fumigatus
分子名称: Aspartate-semialdehyde dehydrogenase, SULFATE ION
著者Dahal, G.P, Viola, R.E.
登録日2016-05-11
公開日2017-01-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structure of a fungal form of aspartate-semialdehyde dehydrogenase from Aspergillus fumigatus.
Acta Crystallogr F Struct Biol Commun, 73, 2017
1BRM
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ASPARTATE BETA-SEMIALDEHYDE DEHYDROGENASE FROM ESCHERICHIA COLI
分子名称: ASPARTATE-SEMIALDEHYDE DEHYDROGENASE
著者Hadfield, A.T, Kryger, G, Ouyang, J, Ringe, D, Petsko, G.A, Viola, R.E.
登録日1998-08-24
公開日1999-06-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of aspartate-beta-semialdehyde dehydrogenase from Escherichia coli, a key enzyme in the aspartate family of amino acid biosynthesis.
J.Mol.Biol., 289, 1999
1GL3
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ASPARTATE BETA-SEMIALDEHYDE DEHYDROGENASE IN COMPLEX WITH NADP AND SUBSTRATE ANALOGUE S-METHYL CYSTEINE SULFOXIDE
分子名称: ASPARTATE-SEMIALDEHYDE DEHYDROGENASE, CYSTEINE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Hadfield, A.T, Kryger, G, Ouyang, J, Ringe, D, Petsko, G.A, Viola, R.E.
登録日2001-08-23
公開日2001-11-01
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Active Site Analysis of the Potential Antimicrobial Target Aspartate Semialdehyde Dehydrogenase.
Biochemistry, 40, 2001
3PWS
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Crystal Structure of Aspartate beta-Semialdehide Dehydrogenase from Streptococcus pneumoniae with 2',5'-Adenosine diphosphate and D-2-aminoadipate
分子名称: (2R)-2-aminohexanedioic acid, ADENOSINE-2'-5'-DIPHOSPHATE, Aspartate-semialdehyde dehydrogenase, ...
著者Pavlovsky, A.G, Viola, R.E.
登録日2010-12-08
公開日2012-01-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Characterization of Inhibitors with Selectivity against Members of a Homologous Enzyme Family.
Chem.Biol.Drug Des., 79, 2012
3PYX
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Crystals Structure of Aspartate beta-Semialdehyde Dehydrogenase complex with NADP and 2-aminoterephthalate
分子名称: 1,2-ETHANEDIOL, 2-aminobenzene-1,4-dicarboxylic acid, Aspartate-semialdehyde dehydrogenase, ...
著者Pavlovsky, A.G, Viola, R.E.
登録日2010-12-13
公開日2012-01-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Characterization of Inhibitors with Selectivity against Members of a Homologous Enzyme Family.
Chem.Biol.Drug Des., 79, 2012
5CEF
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Cystal structure of aspartate semialdehyde dehydrogenase from Cryptococcus neoformans
分子名称: 1,2-ETHANEDIOL, Aspartate-semialdehyde dehydrogenase
著者Dahal, G.P, Viola, R.E.
登録日2015-07-06
公開日2015-11-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of a fungal form of aspartate semialdehyde dehydrogenase from Cryptococcus neoformans.
Acta Crystallogr.,Sect.F, 71, 2015
3C20
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Crystal Structure of Threonine-sensitive Aspartokinase from Methanococcus jannaschii with L-aspartate
分子名称: ASPARTIC ACID, FORMIC ACID, Probable aspartokinase
著者Liu, X, Pavlovsky, A.G, Viola, R.E.
登録日2008-01-24
公開日2008-04-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The Structural Basis for Allosteric Inhibition of a Threonine-sensitive Aspartokinase.
J.Biol.Chem., 283, 2008
3C1N
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Crystal Structure of Allosteric Inhibition Threonine-sensitive Aspartokinase from Methanococcus jannaschii with L-threonine
分子名称: Probable aspartokinase, THREONINE
著者Liu, X, Pavlovshy, A.G, Viola, R.E.
登録日2008-01-23
公開日2008-03-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献The Structural Basis for Allosteric Inhibition of a Threonine-sensitive Aspartokinase.
J.Biol.Chem., 283, 2008
3FMX
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Crystal structure of Tartrate dehydrogenase from Pseudomonas putida complexed with NADH
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, AMMONIUM ION, Tartrate dehydrogenase/decarboxylase
著者Malik, R, Viola, R.E.
登録日2008-12-22
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural Characterization of Tartrate Dehydrogenase: a versatile enzyme catalyzing multiple reactions
To be Published
3FLK
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Crystal Structure of Tartrate Dehydrogenase from Pseudomonas putida in complex with NADH, oxalate and metal ion
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, AMMONIUM ION, ...
著者Malik, R, Viola, R.E.
登録日2008-12-18
公開日2009-12-22
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural characterization of tartrate dehydrogenase: a versatile enzyme catalyzing multiple reactions.
Acta Crystallogr.,Sect.D, 66, 2010
2YXP
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The Effect of Deuteration on Protein Structure A High Resolution Comparison of Hydrogenous and Perdeuterated Haloalkane Dehalogenase
分子名称: Haloalkane dehalogenase
著者Liu, X, Hanson, L, Langan, P, Viola, R.E.
登録日2007-04-27
公開日2007-09-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献The effect of deuteration on protein structure: a high-resolution comparison of hydrogenous and perdeuterated haloalkane dehalogenase.
Acta Crystallogr.,Sect.D, 63, 2007
4MRI
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Human brain aspartoacylase mutant F295S complex with intermediate analog (N-phosphonomethyl-L-aspartate)
分子名称: Aspartoacylase, N-[HYDROXY(METHYL)PHOSPHORYL]-L-ASPARTIC ACID, ZINC ION
著者Wijayasinghe, Y.S, Pavlovsky, A.G, Viola, R.E.
登録日2013-09-17
公開日2014-07-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Aspartoacylase catalytic deficiency as the cause of canavan disease: a structural perspective.
Biochemistry, 53, 2014
4NFR
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Human brain aspartoacylase mutant E285A complex with intermediate analog (N-phosphonomethyl-L-aspartate)
分子名称: Aspartoacylase, N-[HYDROXY(METHYL)PHOSPHORYL]-L-ASPARTIC ACID, ZINC ION
著者Wijayasinghe, Y.S, Pavlovsky, A.G, Viola, R.E.
登録日2013-10-31
公開日2014-07-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Aspartoacylase catalytic deficiency as the cause of canavan disease: a structural perspective.
Biochemistry, 53, 2014
6C07
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Crystal Structure of S-Adenosylmethionine synthetase (MetK/Mat) from Cryptosporidium parvum
分子名称: CHLORIDE ION, MAGNESIUM ION, POTASSIUM ION, ...
著者Ohren, J.F, Viola, R.E.
登録日2017-12-28
公開日2019-01-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of a critical metabolic enzyme: S-adenosylmethionine synthetase from Cryptosporidium parvum.
Acta Crystallogr F Struct Biol Commun, 75, 2019
4MXU
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Human brain aspartoacylase mutant K213E complex with intermediate analog (N-phosphonomethyl-L-aspartate)
分子名称: Aspartoacylase, N-[HYDROXY(METHYL)PHOSPHORYL]-L-ASPARTIC ACID, ZINC ION
著者Wijayasinghe, Y.S, Pavlovsky, A.G, Viola, R.E.
登録日2013-09-26
公開日2014-07-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Aspartoacylase catalytic deficiency as the cause of canavan disease: a structural perspective.
Biochemistry, 53, 2014
4LE5
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Structure of an Unusual S-adenosylmethionine synthetase from Campylobacter jejuni
分子名称: S-adenosylmethionine synthetase
著者Zano, S.P, Pavlovsky, A.G, Viola, R.E.
登録日2013-06-25
公開日2014-02-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of an unusual S-adenosylmethionine synthetase from Campylobacter jejuni.
Acta Crystallogr.,Sect.D, 70, 2014
6C85
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Crystal structure of aspartate semialdehyde dehydrogenase from Blastomyces dermatitidis with p-benzoquinone
分子名称: 1,4-benzoquinone, Aspartate-semialdehyde dehydrogenase
著者Dahal, G.P, Viola, R.E.
登録日2018-01-24
公開日2019-01-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural insights into inhibitor binding to a fungal ortholog of aspartate semialdehyde dehydrogenase.
Biochem.Biophys.Res.Commun., 503, 2018

 

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