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PDB: 57 件

8R4B
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BU of 8r4b by Molmil
Roco protein from C. tepidum in the GTP state bound to the activating Nanobodies NbRoco1 and NbRoco2
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, NbRoco1, NbRoco2, ...
著者Galicia, C, Versees, W.
登録日2023-11-13
公開日2024-05-01
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.88 Å)
主引用文献Structural insights into the GTP-driven monomerization and activation of a bacterial LRRK2 homolog using allosteric nanobodies.
Elife, 13, 2024
6HLU
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BU of 6hlu by Molmil
Crystal structure of the LRR-Roc-COR domain of the Chlorobium tepidum Roco protein
分子名称: Rab family protein
著者Deyaert, E, Versees, W, Singh, R.
登録日2018-09-11
公開日2018-12-26
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.29 Å)
主引用文献Structure and nucleotide-induced conformational dynamics of theChlorobium tepidumRoco protein.
Biochem. J., 476, 2019
4KDT
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BU of 4kdt by Molmil
Structure of an early native-like intermediate of beta2-microglobulin amyloidosis
分子名称: Beta-2-microglobulin, GLYCEROL, Nanobody24, ...
著者Vanderhaegen, S, Fislage, M, Pardon, E, Versees, W, Steyaert, J.
登録日2013-04-25
公開日2013-08-28
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of an early native-like intermediate of beta 2-microglobulin amyloidogenesis.
Protein Sci., 22, 2013
6EMS
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BU of 6ems by Molmil
Crystal Structure of dual specific Trm10 construct from Thermococcus kodakaraensis.
分子名称: tRNA (guanine(9)-/adenine(9)-N1)-methyltransferase
著者Singh, R.K, Versees, W.
登録日2017-10-03
公開日2018-06-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.996 Å)
主引用文献Structural and biochemical analysis of the dual-specificity Trm10 enzyme fromThermococcus kodakaraensisprompts reconsideration of its catalytic mechanism.
RNA, 24, 2018
6EMU
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BU of 6emu by Molmil
Crystal Structure of dual specific Trm10 construct from Thermococcus kodakaraensis.
分子名称: GLYCEROL, S-ADENOSYLMETHIONINE, tRNA (guanine(9)-/adenine(9)-N1)-methyltransferase
著者Singh, R.K, Versees, W.
登録日2017-10-03
公開日2018-06-13
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.29745436 Å)
主引用文献Structural and biochemical analysis of the dual-specificity Trm10 enzyme fromThermococcus kodakaraensisprompts reconsideration of its catalytic mechanism.
RNA, 24, 2018
2AR6
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BU of 2ar6 by Molmil
Pterocarpus angolensis Lectin (PAL) In Complex With The Pentasaccharide M592
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose, CALCIUM ION, ...
著者Buts, L, Garcia-Pino, A, Imberty, A, Amiot, N, Boons, G.J, Beeckmans, S, Versees, W, Wyns, L, Loris, R.
登録日2005-08-19
公開日2006-08-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for the recognition of complex-type biantennary oligosaccharides by Pterocarpus angolensis lectin.
Febs J., 273, 2006
7A17
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BU of 7a17 by Molmil
Crystal structure of the 5-phosphatase domain of Synaptojanin1 bound to its substrate diC8-PI(3,4,5)P3 in complex with a nanobody
分子名称: (2R)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonooxy)cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}propane -1,2-diyl dioctanoate, GLYCEROL, Isoform 2 of Synaptojanin-1, ...
著者Paesmans, J, Galicia, C, Martin, E, Versees, W.
登録日2020-08-12
公開日2020-12-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献A structure of substrate-bound Synaptojanin1 provides new insights in its mechanism and the effect of disease mutations.
Elife, 9, 2020
7A0V
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Crystal structure of the 5-phosphatase domain of Synaptojanin1 in complex with a nanobody
分子名称: GLYCEROL, MAGNESIUM ION, Nanobody 13015, ...
著者Paesmans, J, Galicia, C, Martin, E, Versees, W.
登録日2020-08-11
公開日2020-12-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A structure of substrate-bound Synaptojanin1 provides new insights in its mechanism and the effect of disease mutations.
Elife, 9, 2020
5A7Z
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BU of 5a7z by Molmil
Crystal structure of Sulfolobus acidocaldarius Trm10 at 2.1 angstrom resolution.
分子名称: TRNA (ADENINE(9)-N1)-METHYLTRANSFERASE
著者Van Laer, B, Roovers, M, Wauters, L, Kasprzak, J, Dyzma, M, Deyaert, E, Feller, A, Bujnicki, J, Droogmans, L, Versees, W.
登録日2015-07-10
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and Functional Insights Into tRNA Binding and Adenosine N1-Methylation by an Archaeal Trm10 Homologue.
Nucleic Acids Res., 44, 2016
5A7Y
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BU of 5a7y by Molmil
Crystal structure of Sulfolobus acidocaldarius Trm10 in complex with S-adenosylhomocysteine
分子名称: ACETATE ION, DI(HYDROXYETHYL)ETHER, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Van Laer, B, Roovers, M, Wauters, L, Kasprzak, J, Dyzma, M, Deyaert, E, Feller, A, Bujnicki, J, Droogmans, L, Versees, W.
登録日2015-07-10
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and Functional Insights Into tRNA Binding and Adenosine N1-Methylation by an Archaeal Trm10 Homologue.
Nucleic Acids Res., 44, 2016
5A7T
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BU of 5a7t by Molmil
Crystal structure of Sulfolobus acidocaldarius Trm10 at 2.4 angstrom resolution.
分子名称: DI(HYDROXYETHYL)ETHER, TRNA (ADENINE(9)-N1)-METHYLTRANSFERASE
著者Van Laer, B, Roovers, M, Wauters, L, Kasprzak, J, Dyzma, M, Deyaert, E, Feller, A, Bujnicki, J, Droogmans, L, Versees, W.
登録日2015-07-09
公開日2016-01-13
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and Functional Insights Into tRNA Binding and Adenosine N1-Methylation by an Archaeal Trm10 Homologue.
Nucleic Acids Res., 44, 2016
5HJQ
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BU of 5hjq by Molmil
Crystal structure of the TBC domain of Skywalker/TBC1D24 from Drosophila melanogaster in complex with inositol(1,4,5)triphosphate
分子名称: D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, LD10117p
著者Fischer, B, Paesmans, J, Versees, W.
登録日2016-01-13
公開日2016-09-21
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Skywalker-TBC1D24 has a lipid-binding pocket mutated in epilepsy and required for synaptic function.
Nat.Struct.Mol.Biol., 23, 2016
5HJN
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BU of 5hjn by Molmil
Crystal structure of the TBC domain of Skywalker/TBC1D24 from Drosophila melanogaster
分子名称: LD10117p, SULFATE ION
著者Fischer, B, Paesmans, J, Versees, W.
登録日2016-01-13
公開日2016-09-21
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Skywalker-TBC1D24 has a lipid-binding pocket mutated in epilepsy and required for synaptic function.
Nat.Struct.Mol.Biol., 23, 2016
3TMA
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BU of 3tma by Molmil
Crystal structure of TrmN from Thermus thermophilus
分子名称: PHOSPHATE ION, methyltransferase
著者Fislage, M, Roovers, M, Tuszynska, I, Bujnicki, J.M, Droogmans, L, Versees, W.
登録日2011-08-31
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life.
Nucleic Acids Res., 40, 2012
3TM4
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BU of 3tm4 by Molmil
Crystal structure of Trm14 from Pyrococcus furiosus in complex with S-adenosylmethionine
分子名称: S-ADENOSYLMETHIONINE, tRNA (guanine N2-)-methyltransferase Trm14
著者Fislage, M, Roovers, M, Tuszynska, I, Bujnicki, J.M, Droogmans, L, Versees, W.
登録日2011-08-31
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life.
Nucleic Acids Res., 40, 2012
3FZ0
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BU of 3fz0 by Molmil
Inosine-Guanosine Nucleoside Hydrolase (IG-NH)
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Nucleoside hydrolase, ...
著者Vandemeulebroucke, A, Minici, C, Bruno, I, Muzzolini, L, Tornaghi, P, Parkin, D.W, Schramm, V.L, Versees, W, Steyaert, J, Degano, M.
登録日2009-01-23
公開日2010-01-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and mechanism of the 6-oxopurine nucleosidase from Trypanosoma brucei brucei
Biochemistry, 49, 2010
5MI3
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BU of 5mi3 by Molmil
Structure of phosphorylated translation elongation factor EF-Tu from E. coli
分子名称: Elongation factor Tu 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Talavera, A, Hendrix, J, Versees, W, De Gieter, S, Castro-Roa, D, Jurenas, D, Van Nerom, K, Vandenberk, N, Barth, A, De Greve, H, Hofkens, J, Zenkin, N, Loris, R, Garcia-Pino, A.
登録日2016-11-27
公開日2017-12-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors.
Sci Adv, 4, 2018
5MI8
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Structure of the phosphomimetic mutant of EF-Tu T383E
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, BETA-MERCAPTOETHANOL, ...
著者Talavera, A, Hendrix, J, Versees, W, De Gieter, S, Castro-Roa, D, Jurenas, D, Van Nerom, K, Vandenberk, N, Barth, A, De Greve, H, Hofkens, J, Zenkin, N, Loris, R, Garcia-Pino, A.
登録日2016-11-27
公開日2017-12-20
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors.
Sci Adv, 4, 2018
5MI9
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Structure of the phosphomimetic mutant of the elongation factor EF-Tu T62E
分子名称: Elongation factor Tu 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Talavera, A, Hendrix, J, Versees, W, De Gieter, S, Castro-Roa, D, Jurenas, D, Van Nerom, K, Vandenberk, N, Barth, A, De Greve, H, Hofkens, J, Zenkin, N, Loris, R, Garcia-Pino, A.
登録日2016-11-27
公開日2017-12-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors.
Sci Adv, 4, 2018
8BFR
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BU of 8bfr by Molmil
The E. coli TrpD2 protein YbiB at 1.3 A resolution
分子名称: GLYCEROL, Protein YbiB
著者Deckers, B, Galicia, C, Versees, W.
登録日2022-10-26
公開日2023-02-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献YbiB: a novel interactor of the GTPase ObgE.
Nucleic Acids Res., 51, 2023
8BFT
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BU of 8bft by Molmil
The E. coli TrpD2 protein YbiB in complex with a C-terminal peptide from ObgE
分子名称: DI(HYDROXYETHYL)ETHER, GTPase ObgE/CgtA, Protein YbiB
著者Deckers, B, Galicia, C, Versees, W.
登録日2022-10-26
公開日2023-02-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献YbiB: a novel interactor of the GTPase ObgE.
Nucleic Acids Res., 51, 2023
4CNG
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BU of 4cng by Molmil
Crystal structure of Sulfolobus acidocaldarius TrmJ in complex with S-adenosyl-L-Homocysteine
分子名称: GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, SPOU RRNA METHYLASE
著者Van Laer, B, Somme, J, Roovers, M, Steyaert, J, Droogmans, L, Versees, W.
登録日2014-01-22
公開日2014-07-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Characterization of Two Homologous 2'-O-Methyltransferases Showing Different Specificities for Their tRNA Substrates.
RNA, 20, 2014
4CNE
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BU of 4cne by Molmil
Crystal structure of E.coli TrmJ in complex with S-adenosyl-L- homocysteine
分子名称: DI(HYDROXYETHYL)ETHER, S-ADENOSYL-L-HOMOCYSTEINE, TRNA (CYTIDINE/URIDINE-2'-O-)-METHYLTRANSFERASE TRMJ
著者Van Laer, B, Somme, J, Roovers, M, Steyaert, J, Droogmans, L, Versees, W.
登録日2014-01-22
公開日2014-07-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Characterization of Two Homologous 2'-O-Methyltransferases Showing Different Specificities for Their tRNA Substrates.
RNA, 20, 2014
4CND
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BU of 4cnd by Molmil
Crystal structure of E.coli TrmJ
分子名称: DI(HYDROXYETHYL)ETHER, TRNA (CYTIDINE/URIDINE-2'-O-)-METHYLTRANSFERASE TRMJ
著者Van Laer, B, Somme, J, Roovers, M, Steyaert, J, Droogmans, L, Versees, W.
登録日2014-01-22
公開日2014-07-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Characterization of Two Homologous 2'-O-Methyltransferases Showing Different Specificities for Their tRNA Substrates.
RNA, 20, 2014
4CNF
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BU of 4cnf by Molmil
Crystal structure of Sulfolobus acidocaldarius TrmJ
分子名称: 5'-DEOXY-5'-METHYLTHIOADENOSINE, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Van Laer, B, Somme, J, Roovers, M, Steyaert, J, Droogmans, L, Versees, W.
登録日2014-01-22
公開日2014-07-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Characterization of Two Homologous 2'-O-Methyltransferases Showing Different Specificities for Their tRNA Substrates.
RNA, 20, 2014

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