8P24
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8B51
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![BU of 8b51 by Molmil](/molmil-images/mine/8b51) | Usutu virus methyltransferase domain in complex with sinefungin | Descriptor: | GLYCEROL, GLYCINE, RNA-directed RNA polymerase NS5, ... | Authors: | Ferrero, D.S, Albentosa Gonzalez, L, Mas, A, Verdaguer, N. | Deposit date: | 2022-09-21 | Release date: | 2023-10-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Structure and function of the NS5 methyltransferase domain from Usutu virus. Antiviral Res., 208, 2022
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8B52
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![BU of 8b52 by Molmil](/molmil-images/mine/8b52) | Usutu virus methyltransferase domain in complex with sinefungin | Descriptor: | GLYCEROL, Genome polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Ferrero, D.S, Albentosa Gonzalez, L, Mas, A, Verdaguer, N. | Deposit date: | 2022-09-21 | Release date: | 2023-10-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Structure and function of the NS5 methyltransferase domain from Usutu virus. Antiviral Res., 208, 2022
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8P10
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8P0Y
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6I7P
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![BU of 6i7p by Molmil](/molmil-images/mine/6i7p) | Crystal structure of the full-length Zika virus NS5 protein (Human isolate Z1106033) | Descriptor: | NS5, PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Ferrero, D.S, Ruiz-Arroyo, V.M, Soler, N, Uson, I, Verdaguer, N. | Deposit date: | 2018-11-16 | Release date: | 2019-04-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.975 Å) | Cite: | Supramolecular arrangement of the full-length Zika virus NS5. Plos Pathog., 15, 2019
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5CX6
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![BU of 5cx6 by Molmil](/molmil-images/mine/5cx6) | Crystal structure of Thosea asigna virus RNA-dependent RNA polymerase (RdRP) complexed with CDP | Descriptor: | CYTIDINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Ferrero, D.S, Buxaderas, M, Rodriguez, J.F, Verdaguer, N. | Deposit date: | 2015-07-28 | Release date: | 2015-11-11 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Structure of the RNA-Dependent RNA Polymerase of a Permutotetravirus Suggests a Link between Primer-Dependent and Primer-Independent Polymerases. Plos Pathog., 11, 2015
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5CYR
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![BU of 5cyr by Molmil](/molmil-images/mine/5cyr) | Crystal structure of Thosea asigna virus RNA-dependent RNA polymerase (RdRP) complexed with ATP and ssRNA | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Ferrero, D.S, Buxaderas, M, Rodriguez, J.F, Verdaguer, N. | Deposit date: | 2015-07-30 | Release date: | 2015-11-11 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.504 Å) | Cite: | The Structure of the RNA-Dependent RNA Polymerase of a Permutotetravirus Suggests a Link between Primer-Dependent and Primer-Independent Polymerases. Plos Pathog., 11, 2015
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7PKZ
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![BU of 7pkz by Molmil](/molmil-images/mine/7pkz) | Vault structure in committed conformation | Descriptor: | Major vault protein | Authors: | Guerra, P, Gonzalez-Alamos, M, Llauro, A, Casanas, A, Querol-Audi, J, de Pablo, P, Verdaguer, N. | Deposit date: | 2021-08-27 | Release date: | 2022-03-16 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (9.8 Å) | Cite: | Symmetry disruption commits vault particles to disassembly. Sci Adv, 8, 2022
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4IQX
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![BU of 4iqx by Molmil](/molmil-images/mine/4iqx) | Mutant P44S P169S M296I of Foot-and-mouth disease Virus RNA-dependent RNA polymerase | Descriptor: | 3D polymerase, RNA (5'-R(*AP*UP*GP*GP*GP*CP*C)-3'), RNA (5'-R(*GP*GP*CP*CP*C)-3') | Authors: | Ferrer-Orta, C, Verdaguer, N, Agudo, R, Perez-Luque, R. | Deposit date: | 2013-01-14 | Release date: | 2013-02-06 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape. Plos Pathog., 6, 2010
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1U09
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![BU of 1u09 by Molmil](/molmil-images/mine/1u09) | Footand Mouth Disease Virus RNA-dependent RNA polymerase | Descriptor: | polyprotein | Authors: | Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. | Deposit date: | 2004-07-13 | Release date: | 2004-08-31 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Structure of Foot-and-Mouth Disease Virus RNA-dependent RNA Polymerase and Its Complex with a Template-Primer RNA J.Biol.Chem., 279, 2004
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7OMA
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![BU of 7oma by Molmil](/molmil-images/mine/7oma) | Thosea asigna virus RdRP domain elongation complex | Descriptor: | MAGNESIUM ION, PYROPHOSPHATE 2-, RNA (5'-R(P*AP*AP*AP*UP*UP*UP*U)-3'), ... | Authors: | Ferrero, D.S, Falqui, M, Verdaguer, N. | Deposit date: | 2021-05-21 | Release date: | 2021-07-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Snapshots of a Non-Canonical RdRP in Action. Viruses, 13, 2021
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7OM9
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7OM6
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7OM7
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![BU of 7om7 by Molmil](/molmil-images/mine/7om7) | Thosea asigna virus RdRP domain in complex with RNA and nucleotide UMPNPP | Descriptor: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ... | Authors: | Ferrero, D.S, Falqui, M, Verdaguer, N. | Deposit date: | 2021-05-21 | Release date: | 2021-07-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Snapshots of a Non-Canonical RdRP in Action. Viruses, 13, 2021
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7OM2
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![BU of 7om2 by Molmil](/molmil-images/mine/7om2) | Thosea asigna virus RdRP domain in complex with Mg+2 | Descriptor: | GLYCEROL, MAGNESIUM ION, RNA-dependent RNA polymerase, ... | Authors: | Ferrero, D.S, Falqui, M, Verdaguer, N. | Deposit date: | 2021-05-21 | Release date: | 2021-07-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Snapshots of a Non-Canonical RdRP in Action. Viruses, 13, 2021
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2E9T
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![BU of 2e9t by Molmil](/molmil-images/mine/2e9t) | Foot-and-mouth disease virus RNA-polymerase RNA dependent in complex with a template-primer RNA and 5F-UTP | Descriptor: | 5'-R(*GP*GP*GP*CP*CP*CP*(5FU))-3', 5'-R(P*UP*AP*GP*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ... | Authors: | Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. | Deposit date: | 2007-01-26 | Release date: | 2007-06-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Sequential structures provide insights into the fidelity of RNA replication Proc.Natl.Acad.Sci.Usa, 104, 2007
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2EC0
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![BU of 2ec0 by Molmil](/molmil-images/mine/2ec0) | RNA-dependent RNA polymerase of foot-and-mouth disease virus in complex with a template-primer RNA and ATP | Descriptor: | 5'-R(*GP*GP*GP*CP*CP*CP*A)-3', 5'-R(P*AP*UP*GP*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ... | Authors: | Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. | Deposit date: | 2007-02-09 | Release date: | 2007-06-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Sequential structures provide insights into the fidelity of RNA replication Proc.Natl.Acad.Sci.Usa, 104, 2007
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3NMA
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![BU of 3nma by Molmil](/molmil-images/mine/3nma) | Mutant P169S of Foot-and-mouth disease Virus RNA dependent RNA-polymerase | Descriptor: | 5'-R(*GP*GP*C)-3', 5'-R(P*CP*C)-3', Genome polyprotein, ... | Authors: | Agudo, R, Ferrer-Orta, C, Arias, A, Perez-Luque, R, Verdaguer, N, Domingo, E. | Deposit date: | 2010-06-22 | Release date: | 2011-05-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape. Plos Pathog., 6, 2010
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3NL0
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![BU of 3nl0 by Molmil](/molmil-images/mine/3nl0) | Mutant P44S M296I of Foot-and-mouth disease Virus RNA-dependent RNA polymerase | Descriptor: | 3D polymerase, 5'-R(*G*GP*GP*CP*CP*C)-3', 5'-R(P*UP*GP*GP*GP*CP*CP*C)-3', ... | Authors: | Agudo, R, Ferrer-Orta, C, Arias, A, Perez-Luque, R, Verdaguer, N, Domingo, E. | Deposit date: | 2010-06-21 | Release date: | 2011-07-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape. Plos Pathog., 6, 2010
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3NKY
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![BU of 3nky by Molmil](/molmil-images/mine/3nky) | Structure of a mutant P44S of Foot-and-mouth disease Virus RNA-dependent RNA polymerase | Descriptor: | 3D polymerase, MAGNESIUM ION | Authors: | Agudo, R, Ferrer-Orta, C, Arias, A, Perez-Luque, R, Verdaguer, N, Domingo, E. | Deposit date: | 2010-06-21 | Release date: | 2011-05-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape. Plos Pathog., 6, 2010
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2E9R
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![BU of 2e9r by Molmil](/molmil-images/mine/2e9r) | Foot-and-mouth disease virus RNA-dependent RNA polymerase in complex with a template-primer RNA and with ribavirin | Descriptor: | 5'-R(*CP*AP*UP*GP*GP*GP*CP*CP*C)-3', 5'-R(*CP*CP*C*GP*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ... | Authors: | Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. | Deposit date: | 2007-01-26 | Release date: | 2007-06-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Sequential structures provide insights into the fidelity of RNA replication Proc.Natl.Acad.Sci.Usa, 104, 2007
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6SHW
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![BU of 6shw by Molmil](/molmil-images/mine/6shw) | N-terminal domain of Drosophila X Virus VP3 | Descriptor: | SULFATE ION, Structural polyprotein | Authors: | Ferrero, D.S, Garriga, D, Guerra, P, Uson, I, Verdaguer, N. | Deposit date: | 2019-08-08 | Release date: | 2020-11-18 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure and dsRNA-binding activity of the Birnavirus Drosophila X Virus VP3 protein. J.Virol., 2020
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6SI6
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![BU of 6si6 by Molmil](/molmil-images/mine/6si6) | N-terminal domain of Drosophila X virus VP3 | Descriptor: | GLYCEROL, IMIDAZOLE, Structural polyprotein | Authors: | Ferrero, D.S, Garriga, D, Guerra, P, Uson, I, Verdaguer, N. | Deposit date: | 2019-08-08 | Release date: | 2020-11-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structure and dsRNA-binding activity of the Birnavirus Drosophila X Virus VP3 protein. J.Virol., 2020
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1GMI
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![BU of 1gmi by Molmil](/molmil-images/mine/1gmi) | Structure of the c2 domain from novel protein kinase C epsilon | Descriptor: | MAGNESIUM ION, PROTEIN KINASE C, EPSILON TYPE | Authors: | Ochoa, W.F, Garcia-Garcia, J, Fita, I, Corbalan-Garcia, S, Verdaguer, N, Gomez-Fernandez, J.C. | Deposit date: | 2001-09-14 | Release date: | 2001-10-25 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of the C2 Domain from Novel Protein Kinase Cepsilon. A Membrane Binding Model for Ca(2+ )-Independent C2 Domains J.Mol.Biol., 311, 2001
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