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PDB: 109 件

1M5L
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Structure of wild-type and mutant internal loops from the SL-1 domain of the HIV-1 packaging signal
分子名称: modified HIV-1 packaging signal stem-loop 1 RNA
著者Gallego, J, Greatorex, J, Varani, G, Lever, A.
登録日2002-07-09
公開日2002-09-18
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and stability of wild-type and mutant RNA internal loops from the SL-1 domain of the HIV-1 packaging signal
J.Mol.Biol., 322, 2002
1T4N
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Solution structure of Rnt1p dsRBD
分子名称: Ribonuclease III
著者Leulliot, N, Quevillon-Cheruel, S, Graille, M, van Tilbeurgh, H, Leeper, T.C, Godin, K.S, Edwards, T.E, Sigurdsson, S.T, Rozenkrants, N, Nagel, R.J, Ares, M, Varani, G.
登録日2004-04-30
公開日2004-07-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A new alpha-helical extension promotes RNA binding by the dsRBD of Rnt1p RNAse III
Embo J., 23, 2004
1T4O
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Crystal structure of rnt1p dsRBD
分子名称: Ribonuclease III
著者Leulliot, N, Quevillon-Cheruel, S, Graille, M, van Tilbeurgh, H, Leeper, T.C, Godin, K.S, Edwards, T.E, Sigurdsson, S.T, Rozenkrants, N, Nagel, R.J, Ares Jr, M, Varani, G.
登録日2004-04-30
公開日2004-06-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A new alpha-helical extension promotes RNA binding by the dsRBD of Rnt1p RNAse III
Embo J., 23, 2004
1M82
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SOLUTION STRUCTURE OF THE COMPLEMENTARY RNA PROMOTER OF INFLUENZA A VIRUS
分子名称: RNA (25-MER): THE COMPLEMENTARY RNA PROMOTER OF INFLUENZA A VIRUS
著者Park, C.-J, Bae, S.-H, Lee, M.-K, Varani, G, Choi, B.-S.
登録日2002-07-24
公開日2003-06-03
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the influenza A virus cRNA promoter: implications for differential recognition of viral promoter structures by RNA-dependent RNA polymerase
NUCLEIC ACIDS RES., 31, 2003
1EKZ
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NMR STRUCTURE OF THE COMPLEX BETWEEN THE THIRD DSRBD FROM DROSOPHILA STAUFEN AND A RNA HAIRPIN
分子名称: MATERNAL EFFECT PROTEIN (STAUFEN), STAUFEN DOUBLE-STRANDED RNA BINDING DOMAIN
著者Ramos, A, Grunert, S, Bycroft, M, St Johnston, D, Varani, G.
登録日2000-03-11
公開日2000-08-21
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献RNA recognition by a Staufen double-stranded RNA-binding domain.
EMBO J., 19, 2000
6BF3
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Solution structure of de novo macrocycle design7.3a
分子名称: QDP(DPR)K(2TL)(DAS)
著者Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, D.
登録日2017-10-25
公開日2018-01-10
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BE7
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BU of 6be7 by Molmil
Solution structure of de novo macrocycle Design8.1
分子名称: DDPT(DPR)(DAR)Q(DGN)
著者Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, D.
登録日2017-10-24
公開日2018-01-03
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BEN
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Solution structure of de novo macrocycle design8.2
分子名称: (DAR)Q(DPR)(DGN)R(DGL)PQ
著者Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, B.
登録日2017-10-25
公開日2017-12-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BES
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Solution structure of de novo macrocycle design11_ss
分子名称: (DAL)Q(DPR)(DCY)(DLY)DS(DTY)(DCY)P(DSN)
著者Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, D.
登録日2017-10-25
公開日2017-12-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BEW
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Solution structure of de novo macrocycle design7.2
分子名称: (DHI)P(DAS)(DGN)(DSN)(DGL)P
著者Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, D.
登録日2017-10-25
公開日2017-12-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BET
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Solution structure of de novo macrocycle design12_ss
分子名称: H(DPR)(DVA)CIP(DPR)E(DLY)VC(DGL)
著者Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, D.
登録日2017-10-25
公開日2017-12-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BF5
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BU of 6bf5 by Molmil
Solution structure of de novo macrocycle design7.3a
分子名称: QDP(DPR)K(DTH)(DAS)
著者Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, D.
登録日2017-10-25
公開日2018-01-10
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BER
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BU of 6ber by Molmil
Solution structure of de novo macrocycle design10.2
分子名称: E(DVA)DP(DGL)(DHI)(DPR)N(DAL)(DPR)
著者Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, D.
登録日2017-10-25
公開日2017-12-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BEO
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BU of 6beo by Molmil
Solution structure of de novo macrocycle design9.1
分子名称: (DPR)PY(DHI)PKDL(DGN)
著者Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, D.
登録日2017-10-25
公開日2017-12-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BEQ
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BU of 6beq by Molmil
Solution structure of de novo macrocycle design10.1
分子名称: AAR(DVA)(DPR)R(DLE)(DTH)PE
著者Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, D.
登録日2017-10-25
公開日2018-01-10
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BE9
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BU of 6be9 by Molmil
Solution structure of de novo macrocycle design7.1
分子名称: T(DLY)NDT(DSG)(DPR)
著者Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, B.
登録日2017-10-24
公開日2017-12-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BEU
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BU of 6beu by Molmil
Solution structure of de novo macrocycle design14_ss
分子名称: (DCY)N(DVA)(DPR)DVYC(DPR)(DSG)KY(DVA)(DPR)
著者Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, D.
登録日2017-10-25
公開日2017-12-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6B3X
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BU of 6b3x by Molmil
Crystal structure of CstF-50 in complex with CstF-77
分子名称: Cleavage stimulation factor subunit 1, Cleavage stimulation factor subunit 3
著者Yang, W, Hsu, P, Yang, F, Song, J.E, Varani, G.
登録日2017-09-25
公開日2017-11-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Reconstitution of the CstF complex unveils a regulatory role for CstF-50 in recognition of 3'-end processing signals.
Nucleic Acids Res., 46, 2018
6C2V
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BU of 6c2v by Molmil
Solution structure of a phosphate-loop protein
分子名称: phosphate-loop protein
著者Yang, F, Yang, W, Lin, Y.R, Romero Romero, M.L, Tawfik, D, Baker, D, Varani, G.
登録日2018-01-09
公開日2018-11-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Simple yet functional phosphate-loop proteins.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6C2U
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BU of 6c2u by Molmil
Solution structure of a phosphate-loop protein
分子名称: phosphate-loop protein
著者Yang, F, Yang, W, Lin, Y.R, Romero Romero, M.L, Tawfik, D, Baker, D, Varani, G.
登録日2018-01-09
公開日2018-11-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Simple yet functional phosphate-loop proteins.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6D2U
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BU of 6d2u by Molmil
Solution structure of a ultra-high affinity macrocycle bound to HIV-1 TAR RNA
分子名称: DAB-VAL-ARG-THR-ARG-LYS-GLY-ARG-ARG-ILE-NOR-ILE-DPR-PRO, RNA (29-MER)
著者Shortridge, M.D, Varani, G.
登録日2018-04-13
公開日2018-12-12
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献An ultra-high affinity ligand of HIV-1 TAR reveals the RNA structure recognized by P-TEFb.
Nucleic Acids Res., 47, 2019
2MJ3
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BU of 2mj3 by Molmil
Backbone 1H, 13C, and 15N Chemical Shift Assignments and structure of Iron-sulfur cluster binding protein from Ehrlichia chaffeensis
分子名称: Iron-sulfur cluster binding protein
著者Barnwal, R, Varani, G, Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2013-12-23
公開日2014-01-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Backbone 1H, 13C, and 15N Chemical Shift Assignments and structure of Iron-sulfur cluster binding protein from Ehrlichia chaffeensis
To be Published
2M4Y
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Rubredoxin type protein from Mycobacterium ulcerans
分子名称: Rubredoxin
著者Barnwal, R, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2013-02-11
公開日2013-03-13
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of Rubredoxin type protein from Mycobacterium ulcerans
To be Published
2MCQ
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NMR structure of a BolA-like hypothetical protein RP812 from Rickettsia prowazekii, Seattle structural genomics center for infectious disease (SSGCID)
分子名称: Uncharacterized protein RP812
著者Chen, Y, Barnwal, R, Yang, F, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2013-08-22
公開日2013-10-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR structure of a BolA-like hypothetical protein RP812 from Rickettsia prowazekii, Seattle structural genomics center for infectious disease (SSGCID)
To be Published
2LWK
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Solution structure of small molecule-influenza RNA complex
分子名称: 6,7-dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine, RNA (32-MER)
著者Lee, M.-K, Varani, G, Choi, B.-S, Pellecchia, M, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-08-01
公開日2012-08-29
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献A novel small-molecule binds to the influenza A virus RNA promoter and inhibits viral replication.
Chem.Commun.(Camb.), 50, 2014

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件を2024-07-17に公開中

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