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PDB: 143 件

6PYB
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Sex Hormone-binding globulin mutant E176K in complex with DVT
分子名称: 4,4'-[(3R,4R)-oxolane-3,4-diylbis(methylene)]bis(2-methoxyphenol), CALCIUM ION, Sex hormone-binding globulin
著者Round, P.W, Das, S, Van Petegem, F.
登録日2019-07-29
公開日2019-12-25
最終更新日2020-02-12
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular interactions between sex hormone-binding globulin and nonsteroidal ligands that enhance androgen activity.
J.Biol.Chem., 295, 2020
3QR5
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Structure of the first domain of a cardiac Ryanodine Receptor mutant with exon 3 deleted
分子名称: Cardiac Ca2+ release channel
著者Lobo, P.A, Van Petegem, F.
登録日2011-02-17
公開日2011-06-08
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The deletion of exon 3 in the cardiac ryanodine receptor is rescued by beta strand switching.
Structure, 19, 2011
5DZF
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Crystal Structure of the catalytic nucleophile mutant of VvEG16 in complex with a mixed-linkage glucan octasaccharide
分子名称: SULFATE ION, beta-D-glucopyranose, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ...
著者McGregor, N.G.S, Tung, C.C, Van Petegem, F, Brumer, H.
登録日2015-09-25
公開日2016-09-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystallographic insight into the evolutionary origins of xyloglucan endotransglycosylases and endohydrolases.
Plant J., 89, 2017
4MZ3
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Crystal structure of the voltage-gated sodium channel beta 4 subunit extracellular domain, C131W mutant
分子名称: Sodium channel subunit beta-4
著者Das, S, Van Petegem, F.
登録日2013-09-28
公開日2013-12-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.741 Å)
主引用文献Crystallographic insights into sodium-channel modulation by the beta 4 subunit.
Proc.Natl.Acad.Sci.USA, 110, 2013
3ILA
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Crystal structure of rabbit ryanodine receptor 1 N-terminal domain (9-205)
分子名称: Ryanodine receptor 1
著者Lobo, P.A, Van Petegem, F.
登録日2009-08-06
公開日2009-11-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structures of the N-terminal domains of cardiac and skeletal muscle ryanodine receptors: insights into disease mutations.
Structure, 17, 2009
4MZ2
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Crystal structure of the voltage-gated sodium channel beta 4 subunit extracellular domain
分子名称: Sodium channel subunit beta-4
著者Das, S, Van Petegem, F.
登録日2013-09-28
公開日2013-12-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.722 Å)
主引用文献Crystallographic insights into sodium-channel modulation by the beta 4 subunit.
Proc.Natl.Acad.Sci.USA, 110, 2013
4P9J
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Crystal Structure of rabbit Ryanodine Receptor 1 SPRY2 Domain (1070-1246)
分子名称: Ryanodine receptor 1
著者Lau, K, Van Petegem, F.
登録日2014-04-04
公開日2014-11-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.
Nat Commun, 5, 2014
4P9I
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Crystal Structure of mouse Ryanodine Receptor 2 SPRY2 Domain (1080-1253)
分子名称: Ryanodine receptor 2
著者Lau, K, Van Petegem, F.
登録日2014-04-04
公開日2014-11-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.3401 Å)
主引用文献Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.
Nat Commun, 5, 2014
4P9L
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Crystal Structure of mouse Ryanodine Receptor 2 SPRY2 Domain (1080-1253) disease mutant A1107M
分子名称: Ryanodine receptor 2
著者Lau, K, Van Petegem, F.
登録日2014-04-04
公開日2014-11-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.4361 Å)
主引用文献Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.
Nat Commun, 5, 2014
6VSV
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Crystal structure of a disease mutant of the Voltage-gated Sodium Channel Beta 4 subunit extracellular domain
分子名称: Sodium channel subunit beta-4
著者Das, S, Van Petegem, F.
登録日2020-02-12
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Biophysical Investigation of Sodium Channel Interaction with beta-Subunit Variants Associated with Arrhythmias.
Bioelectricity, 2, 2020
7KR6
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Glycoside hydrolase family 16 endo-glucanase from Bacteroides ovatus in complex with G4G3G-2F-DNP
分子名称: Glycoside hydrolase family 16 protein, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-3)-2-deoxy-2-fluoro-alpha-D-glucopyranose
著者Tamura, K, Brumer, H, van Petegem, F.
登録日2020-11-18
公開日2021-05-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Orthogonal Active-Site Labels for Mixed-Linkage endo-beta-Glucanases.
Acs Chem.Biol., 16, 2021
5KHI
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HCN2 CNBD in complex with purine riboside-3', 5'-cyclic monophosphate (cPuMP)
分子名称: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2, Purine riboside-3',5'-cyclic monophosphate
著者Ng, L.C.T, Putrenko, I, Baronas, V, Van Petegem, F, Accili, E.A.
登録日2016-06-14
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Cyclic Purine and Pyrimidine Nucleotides Bind to the HCN2 Ion Channel and Variably Promote C-Terminal Domain Interactions and Opening.
Structure, 24, 2016
5KHK
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HCN2 CNBD in complex with 2-aminopurine riboside-3', 5'-cyclic monophosphate (2-NH2-cPuMP)
分子名称: 2-Aminopurine riboside-3',5'-cyclic monophosphate, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
著者Ng, L.C.T, Putrenko, I, Baronas, V, Van Petegem, F, Accili, E.A.
登録日2016-06-14
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Cyclic Purine and Pyrimidine Nucleotides Bind to the HCN2 Ion Channel and Variably Promote C-Terminal Domain Interactions and Opening.
Structure, 24, 2016
5KHH
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HCN2 CNBD in complex with inosine-3', 5'-cyclic monophosphate (cIMP)
分子名称: Inosine-3',5'-cyclic monophosphate, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
著者Ng, L.C.T, Putrenko, I, Baronas, V, Van Petegem, F, Accili, E.A.
登録日2016-06-14
公開日2016-09-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Cyclic Purine and Pyrimidine Nucleotides Bind to the HCN2 Ion Channel and Variably Promote C-Terminal Domain Interactions and Opening.
Structure, 24, 2016
6U39
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2.4 Angstrom crystal structure of the D129G Ca-CaM:CaV1.2 IQ domain complex
分子名称: CALCIUM ION, Calmodulin-1, Voltage-dependent L-type calcium channel subunit alpha-1C
著者Wang, K, Van Petegem, F.
登録日2019-08-21
公開日2020-02-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Arrhythmia mutations in calmodulin can disrupt cooperativity of Ca2+binding and cause misfolding.
J. Physiol. (Lond.), 598, 2020
7KV7
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BU of 7kv7 by Molmil
Surface glycan-binding protein B from Bacteroides fluxus in complex with laminaritriose
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, LYSINE, ...
著者Tamura, K, Brumer, H, Van Petegem, F.
登録日2020-11-26
公開日2021-02-17
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Distinct protein architectures mediate species-specific beta-glucan binding and metabolism in the human gut microbiota.
J.Biol.Chem., 296, 2021
7KV5
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Surface glycan-binding protein B from Bacteroides fluxus
分子名称: DI(HYDROXYETHYL)ETHER, GUANIDINE, PKD domain protein
著者Tamura, K, Brumer, H, Van Petegem, F.
登録日2020-11-26
公開日2021-02-17
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Distinct protein architectures mediate species-specific beta-glucan binding and metabolism in the human gut microbiota.
J.Biol.Chem., 296, 2021
7KV1
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Surface glycan-binding protein A from Bacteroides uniformis
分子名称: 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, COBALT HEXAMMINE(III), ...
著者Tamura, K, Brumer, H, Van Petegem, F.
登録日2020-11-26
公開日2021-02-17
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Distinct protein architectures mediate species-specific beta-glucan binding and metabolism in the human gut microbiota.
J.Biol.Chem., 296, 2021
7KV2
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Surface glycan-binding protein A from Bacteroides thetaiotaomicron
分子名称: 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, RagB/SusD family nutrient uptake outer membrane protein, ...
著者Tamura, K, Brumer, H, Van Petegem, F.
登録日2020-11-26
公開日2021-02-17
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Distinct protein architectures mediate species-specific beta-glucan binding and metabolism in the human gut microbiota.
J.Biol.Chem., 296, 2021
3DVJ
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BU of 3dvj by Molmil
Crystal Structure of Ca2+/CaM-CaV2.2 IQ domain (without cloning artifact, HM to TV) complex
分子名称: CALCIUM ION, Calmodulin, Voltage-dependent N-type calcium channel subunit alpha-1B
著者Kim, E.Y, Rumpf, C.H, Fujiwara, Y, Cooley, E.S, Van Petegem, F, Minor, D.L.
登録日2008-07-18
公開日2008-11-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of Ca(V)2 Ca(2+)/CaM-IQ Domain Complexes Reveal Binding Modes that Underlie Calcium-Dependent Inactivation and Facilitation.
Structure, 16, 2008
3DVE
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BU of 3dve by Molmil
Crystal Structure of Ca2+/CaM-CaV2.2 IQ domain complex
分子名称: CALCIUM ION, Calmodulin, NICKEL (II) ION, ...
著者Kim, E.Y, Rumpf, C.H, Fujiwara, Y, Cooley, E.S, Van Petegem, F, Minor, D.L.
登録日2008-07-18
公開日2008-11-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structures of Ca(V)2 Ca(2+)/CaM-IQ Domain Complexes Reveal Binding Modes that Underlie Calcium-Dependent Inactivation and Facilitation.
Structure, 16, 2008
3DVM
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Crystal Structure of Ca2+/CaM-CaV2.1 IQ domain complex
分子名称: CALCIUM ION, Calmodulin, Voltage-dependent P/Q-type calcium channel subunit alpha-1A
著者Kim, E.Y, Rumpf, C.H, Fujiwara, Y, Cooley, E.S, Van Petegem, F, Minor, D.L.
登録日2008-07-18
公開日2008-11-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of Ca(V)2 Ca(2+)/CaM-IQ Domain Complexes Reveal Binding Modes that Underlie Calcium-Dependent Inactivation and Facilitation.
Structure, 16, 2008
3DVK
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Crystal Structure of Ca2+/CaM-CaV2.3 IQ domain complex
分子名称: CALCIUM ION, Calmodulin, Voltage-dependent R-type calcium channel subunit alpha-1E
著者Kim, E.Y, Rumpf, C.H, Fujiwara, Y, Cooley, E.S, Van Petegem, F, Minor, D.L.
登録日2008-07-18
公開日2008-11-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of Ca(V)2 Ca(2+)/CaM-IQ Domain Complexes Reveal Binding Modes that Underlie Calcium-Dependent Inactivation and Facilitation.
Structure, 16, 2008
6VRR
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Crystal structure of a disease mutant of the Voltage-gated Sodium Channel Beta 2 subunit extracellular domain
分子名称: GLYCEROL, Sodium channel subunit beta-2
著者Das, S, Van Petegem, F.
登録日2020-02-09
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Biophysical Investigation of Sodium Channel Interaction with beta-Subunit Variants Associated with Arrhythmias.
Bioelectricity, 2, 2020
6W1N
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BU of 6w1n by Molmil
Pig Ryanodine Receptor (WT) in 5mM EGTA condition
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor, ZINC ION
著者Woll, K.W, Haji-Ghassemi, O, Van Petegem, F.
登録日2020-03-04
公開日2021-01-06
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM.
Nat Commun, 12, 2021

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