3ABT
 
 | | Crystal Structure of LSD1 in complex with trans-2-pentafluorophenylcyclopropylamine | | Descriptor: | Lysine-specific histone demethylase 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S)-2,3,4-trihydroxy-5-[(1R,3R,3aS)-1-hydroxy-10,11-dimethyl-4,6-dioxo-3-(pentafluorophenyl)-2,3,5,6-tetrahydro-1H-benzo[g]pyrrolo[2,1-e]pteridin-8(4H)-yl]pentyl dihydrogen diphosphate | | Authors: | Mimasu, S, Umezawa, N, Sato, S, Higuchi, T, Umehara, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2009-12-21 | | Release date: | 2010-07-07 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structurally Designed trans-2-Phenylcyclopropylamine Derivatives Potently Inhibit Histone Demethylase LSD1/KDM1
Biochemistry, 49, 2010
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5WRK
 | | Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y608 peptide | | Descriptor: | AP-2 complex subunit mu, Insulin receptor substrate 1, NICKEL (II) ION | | Authors: | Yoneyama, Y, Niwa, H, Umehara, T, Yokoyama, S, Hakuno, F, Takahashi, S. | | Deposit date: | 2016-12-02 | | Release date: | 2017-12-06 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.62 Å) | | Cite: | IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling
Elife, 7, 2018
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5WRL
 | | Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y628 peptide | | Descriptor: | AP-2 complex subunit mu, Insulin receptor substrate 1 | | Authors: | Yoneyama, Y, Niwa, H, Umehara, T, Yokoyama, S, Hakuno, F, Takahashi, S. | | Deposit date: | 2016-12-02 | | Release date: | 2017-12-06 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.095 Å) | | Cite: | IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling
Elife, 7, 2018
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5WRM
 | | Mu2 subunit of the clathrin adaptor complex AP2 in complex with IRS-1 Y658 peptide | | Descriptor: | AP-2 complex subunit mu, Insulin receptor substrate 1 | | Authors: | Yoneyama, Y, Niwa, H, Umehara, T, Yokoyama, S, Hakuno, F, Takahashi, S. | | Deposit date: | 2016-12-02 | | Release date: | 2017-12-06 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.597 Å) | | Cite: | IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling
Elife, 7, 2018
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5X17
 | | Crystal structure of murine CK1d in complex with ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Casein kinase I isoform delta, SULFATE ION | | Authors: | Kikuchi, M, Shinohara, Y, Ueda, H.R, Umehara, T. | | Deposit date: | 2017-01-25 | | Release date: | 2017-10-04 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Temperature-Sensitive Substrate and Product Binding Underlie Temperature-Compensated Phosphorylation in the Clock
Mol. Cell, 67, 2017
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2RSJ
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2RSH
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5X50
 | | RNA Polymerase II from Komagataella Pastoris (Type-2 crystal) | | Descriptor: | DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, RNA polymerase II subunit, ... | | Authors: | Ehara, H, Umehara, T, Sekine, S, Yokoyama, S. | | Deposit date: | 2017-02-14 | | Release date: | 2017-05-17 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (4.293 Å) | | Cite: | Crystal structure of RNA polymerase II from Komagataella pastoris
Biochem. Biophys. Res. Commun., 487, 2017
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5X51
 | | RNA Polymerase II from Komagataella Pastoris (Type-3 crystal) | | Descriptor: | DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, RNA polymerase II subunit, ... | | Authors: | Ehara, H, Umehara, T, Sekine, S, Yokoyama, S. | | Deposit date: | 2017-02-14 | | Release date: | 2017-05-17 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (6.996 Å) | | Cite: | Crystal structure of RNA polymerase II from Komagataella pastoris
Biochem. Biophys. Res. Commun., 487, 2017
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5X4Z
 | | RNA Polymerase II from Komagataella Pastoris (Type-1 crystal) | | Descriptor: | DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, RNA polymerase II subunit, ... | | Authors: | Ehara, H, Umehara, T, Sekine, S, Yokoyama, S. | | Deposit date: | 2017-02-14 | | Release date: | 2017-05-17 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (7.8 Å) | | Cite: | Crystal structure of RNA polymerase II from Komagataella pastoris
Biochem. Biophys. Res. Commun., 487, 2017
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3A99
 | | Structure of PIM-1 kinase crystallized in the presence of P27KIP1 Carboxy-terminal peptide | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Proto-oncogene serine/threonine-protein kinase pim-1 | | Authors: | Morishita, D, Takami, M, Yoshikawa, S, Katayama, R, Sato, S, Kukimoto-Niino, M, Umehara, T, Shirouzu, M, Sekimizu, K, Yokoyama, S, Fujita, N. | | Deposit date: | 2009-10-22 | | Release date: | 2010-11-03 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Cell-permeable carboxyl-terminal p27(Kip1) peptide exhibits anti-tumor activity by inhibiting Pim-1 kinase
J.Biol.Chem., 286, 2011
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3AJI
 | | Structure of Gankyrin-S6ATPase photo-cross-linked site-specifically, and incoporated by genetic code expansion | | Descriptor: | 26S proteasome non-ATPase regulatory subunit 10, Proteasome (Prosome, macropain) 26S subunit, ... | | Authors: | Sato, S, Mimasu, S, Sato, A, Hino, N, Sakamoto, K, Umehara, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2010-06-07 | | Release date: | 2010-12-22 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Crystallographic study of a site-specifically cross-linked protein complex with a genetically incorporated photoreactive amino acid
Biochemistry, 50, 2011
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2CUJ
 | | Solution structure of SWIRM domain of mouse transcriptional adaptor 2-like | | Descriptor: | transcriptional adaptor 2-like | | Authors: | Yoneyama, M, Umehara, T, Sato, M, Tochio, N, Koshiba, S, Inoue, M, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-05-26 | | Release date: | 2005-11-26 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structural and Functional Differences of SWIRM Domain Subtypes
J.Mol.Biol., 369, 2007
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2CU7
 | | Solution structure of the SANT domain of human KIAA1915 protein | | Descriptor: | KIAA1915 protein | | Authors: | Yoneyama, M, Umehara, T, Saito, K, Tochio, N, Koshiba, S, Inoue, M, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-05-25 | | Release date: | 2005-11-25 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structural and Functional Differences of SWIRM Domain Subtypes
J.Mol.Biol., 369, 2007
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2DCE
 | | Solution structure of the SWIRM domain of human KIAA1915 protein | | Descriptor: | KIAA1915 protein | | Authors: | Yoneyama, M, Tochio, N, Umehara, T, Koshiba, S, Inoue, M, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-01-06 | | Release date: | 2006-07-06 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structural and Functional Differences of SWIRM Domain Subtypes
J.Mol.Biol., 369, 2007
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2COM
 | | The solution structure of the SWIRM domain of human LSD1 | | Descriptor: | Lysine-specific histone demethylase 1 | | Authors: | Tochio, N, Umehara, T, Koshiba, S, Inoue, M, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-05-18 | | Release date: | 2005-11-18 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the SWIRM domain of human histone demethylase LSD1
Structure, 14, 2006
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2ELJ
 | | Solution structure of the SWIRM domain of baker's yeast Transcriptional adapter 2 | | Descriptor: | Transcriptional adapter 2 | | Authors: | Yoneyama, M, Tochio, N, Koshiba, S, Tomizawa, T, Watanabe, S, Harada, T, Umehara, T, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-03-27 | | Release date: | 2007-10-02 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the SWIRM domain of baker's yeast Transcriptional adapter 2
To be Published
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2ELV
 | | Solution structure of the 6th C2H2 zinc finger of human Zinc finger protein 406 | | Descriptor: | ZINC ION, Zinc finger protein 406 | | Authors: | Tochio, N, Yoneyama, M, Koshiba, S, Tomizawa, T, Watanabe, S, Harada, T, Umehara, T, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-03-27 | | Release date: | 2008-04-01 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the 6th C2H2 zinc finger of human Zinc finger protein 406
To be Published
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2ELL
 | | Solution structure of the Leucine Rich Repeat of human Acidic leucine-rich nuclear phosphoprotein 32 family member B | | Descriptor: | Acidic leucine-rich nuclear phosphoprotein 32 family member B | | Authors: | Tochio, N, Koshiba, S, Watanabe, S, Harada, T, Umehara, T, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-03-27 | | Release date: | 2008-04-01 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution structure of histone chaperone ANP32B: interaction with core histones H3-H4 through its acidic concave domain.
J.Mol.Biol., 401, 2010
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2CY1
 | | Crystal structure of APE1850 | | Descriptor: | NusA protein homolog | | Authors: | Shibata, R, Bessho, Y, Umehara, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-07-04 | | Release date: | 2006-01-04 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystallization of the archaeal transcription termination factor NusA: a significant decrease in twinning under microgravity conditions
Acta Crystallogr.,Sect.F, 63, 2007
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2ELH
 | | Solution structure of the CENP-B N-terminal DNA-binding domain of fruit fly distal antenna CG11849-PA | | Descriptor: | CG11849-PA | | Authors: | Tochio, N, Koshiba, S, Watanabe, S, Harada, T, Umehara, T, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-03-27 | | Release date: | 2008-04-01 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the CENP-B N-terminal DNA-binding domain of fruit fly distal antenna CG11849-PA
To be Published
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2ELR
 | | Solution structure of the 15th C2H2 zinc finger of human Zinc finger protein 406 | | Descriptor: | ZINC ION, Zinc finger protein 406 | | Authors: | Tochio, N, Yoneyama, M, Koshiba, S, Watanabe, S, Harada, T, Umehara, T, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-03-27 | | Release date: | 2008-04-01 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the 15th C2H2 zinc finger of human Zinc finger protein 406
To be Published
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2ELO
 | | Solution structure of the 12th C2H2 zinc finger of human Zinc finger protein 406 | | Descriptor: | ZINC ION, Zinc finger protein 406 | | Authors: | Tochio, N, Yoneyama, M, Koshiba, S, Watanabe, S, Harada, T, Umehara, T, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-03-27 | | Release date: | 2008-04-01 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the 12th C2H2 zinc finger of human Zinc finger protein 406
To be Published
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2ELW
 | | Solution structure of the 5th C2H2 zinc finger of mouse Zinc finger protein 406 | | Descriptor: | ZINC ION, Zinc finger protein 406 | | Authors: | Tochio, N, Yoneyama, M, Koshiba, S, Watanabe, S, Harada, T, Umehara, T, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-03-27 | | Release date: | 2008-04-01 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the 5th C2H2 zinc finger of mouse Zinc finger protein 406
To be Published
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2ELM
 | | Solution structure of the 10th C2H2 zinc finger of human Zinc finger protein 406 | | Descriptor: | ZINC ION, Zinc finger protein 406 | | Authors: | Tochio, N, Yoneyama, M, Koshiba, S, Watanabe, S, Harada, T, Umehara, T, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-03-27 | | Release date: | 2008-04-01 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the 10th C2H2 zinc finger of human Zinc finger protein 406
To be Published
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