7CDG
 
 | | Crystal structure of LSD1-CoREST in complex with PRSFLVRRR peptide | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Lysine-specific histone demethylase 1A, ... | | 著者 | Kikuchi, M, Kitagawa, H, Sato, S, Umezawa, N, Higuchi, T, Umehara, T. | | 登録日 | 2020-06-19 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure-Based Identification of Potent Lysine-Specific Demethylase 1 Inhibitor Peptides and Temporary Cyclization to Enhance Proteolytic Stability and Cell Growth-Inhibitory Activity.
J.Med.Chem., 64, 2021
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7CDD
 | | Crystal structure of LSD1-CoREST in complex with PRSFLVRR peptide | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Lysine-specific histone demethylase 1A, ... | | 著者 | Kikuchi, M, Kitagawa, H, Sato, S, Umezawa, N, Higuchi, T, Umehara, T. | | 登録日 | 2020-06-19 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | Structure-Based Identification of Potent Lysine-Specific Demethylase 1 Inhibitor Peptides and Temporary Cyclization to Enhance Proteolytic Stability and Cell Growth-Inhibitory Activity.
J.Med.Chem., 64, 2021
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7CDE
 | | Crystal structure of LSD1-CoREST in complex with PRSFLVRKR peptide | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Lysine-specific histone demethylase 1A, ... | | 著者 | Kikuchi, M, Kitagawa, H, Sato, S, Umezawa, N, Higuchi, T, Umehara, T. | | 登録日 | 2020-06-19 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Structure-Based Identification of Potent Lysine-Specific Demethylase 1 Inhibitor Peptides and Temporary Cyclization to Enhance Proteolytic Stability and Cell Growth-Inhibitory Activity.
J.Med.Chem., 64, 2021
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5YJB
 | | LSD1-CoREST in complex with 4-[5-(piperidin-4-ylmethoxy)-2-(p-tolyl)pyridin-3-yl]benzonitrile | | 分子名称: | 4-[2-(4-methylphenyl)-5-(piperidin-4-ylmethoxy)pyridin-3-yl]benzenecarbonitrile, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | 著者 | Niwa, H, Sato, S, Hashimoto, T, Matsuno, K, Umehara, T. | | 登録日 | 2017-10-10 | | 公開日 | 2018-07-04 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | | 主引用文献 | Crystal Structure of LSD1 in Complex with 4-[5-(Piperidin-4-ylmethoxy)-2-(p-tolyl)pyridin-3-yl]benzonitrile.
Molecules, 23, 2018
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5X4Z
 | | RNA Polymerase II from Komagataella Pastoris (Type-1 crystal) | | 分子名称: | DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, RNA polymerase II subunit, ... | | 著者 | Ehara, H, Umehara, T, Sekine, S, Yokoyama, S. | | 登録日 | 2017-02-14 | | 公開日 | 2017-05-17 | | 実験手法 | X-RAY DIFFRACTION (7.8 Å) | | 主引用文献 | Crystal structure of RNA polymerase II from Komagataella pastoris
Biochem. Biophys. Res. Commun., 487, 2017
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2RV6
 | | Solution structures of the DNA-binding domains (ZF2-ZF3-ZF4) of immune-related zinc-finger protein ZFAT | | 分子名称: | ZINC ION, Zinc finger protein ZFAT | | 著者 | Tochio, N, Umehara, T, Kigawa, T, Yokoyama, S. | | 登録日 | 2015-01-26 | | 公開日 | 2015-04-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT
J.Struct.Funct.Genom., 16, 2015
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2RV0
 | | Solution structures of the DNA-binding domain (ZF12) of immune-related zinc-finger protein ZFAT | | 分子名称: | ZINC ION, Zinc finger protein ZFAT | | 著者 | Tochio, N, Umehara, T, Kigawa, T, Yokoyama, S. | | 登録日 | 2015-01-26 | | 公開日 | 2015-04-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT
J.Struct.Funct.Genom., 16, 2015
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2RV2
 | | Solution structures of the DNA-binding domain (ZF14) of immune-related zinc-finger protein ZFAT | | 分子名称: | ZINC ION, Zinc finger protein ZFAT | | 著者 | Tochio, N, Umehara, T, Kigawa, T, Yokoyama, S. | | 登録日 | 2015-01-26 | | 公開日 | 2015-04-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT
J.Struct.Funct.Genom., 16, 2015
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2RUX
 | | Solution structures of the DNA-binding domain (ZF6) of immune-related zinc-finger protein ZFAT | | 分子名称: | ZINC ION, Zinc finger protein ZFAT | | 著者 | Tochio, N, Umehara, T, Kigawa, T, Yokoyama, S. | | 登録日 | 2015-01-26 | | 公開日 | 2015-04-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT
J.Struct.Funct.Genom., 16, 2015
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2RV4
 | | Solution structures of the DNA-binding domain (ZF5) of mouse immune-related zinc-finger protein ZFAT | | 分子名称: | ZINC ION, Zinc finger protein ZFAT | | 著者 | Tochio, N, Umehara, T, Kigawa, T, Yokoyama, S. | | 登録日 | 2015-01-26 | | 公開日 | 2015-04-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT
J.Struct.Funct.Genom., 16, 2015
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2RV3
 | | Solution structures of the DNA-binding domain (ZF15) of immune-related zinc-finger protein ZFAT | | 分子名称: | ZINC ION, Zinc finger protein ZFAT | | 著者 | Tochio, N, Umehara, T, Kigawa, T, Yokoyama, S. | | 登録日 | 2015-01-26 | | 公開日 | 2015-04-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT
J.Struct.Funct.Genom., 16, 2015
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2RUT
 | | Solution structures of the DNA-binding domain (ZF2) of immune-related zinc-finger protein ZFAT | | 分子名称: | ZINC ION, Zinc finger protein ZFAT | | 著者 | Tochio, N, Umehara, T, Kigawa, T, Yokoyama, S. | | 登録日 | 2015-01-26 | | 公開日 | 2015-04-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT.
J Struct Funct Genomics, 16, 2015
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2RUY
 | | Solution structures of the DNA-binding domain (ZF10) of immune-related zinc-finger protein ZFAT | | 分子名称: | ZINC ION, Zinc finger protein ZFAT | | 著者 | Tochio, N, Umehara, T, Kigawa, T, Yokoyama, S. | | 登録日 | 2015-01-26 | | 公開日 | 2015-04-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT
J.Struct.Funct.Genom., 16, 2015
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2RUV
 | | Solution structures of the DNA-binding domain (ZF4) of immune-related zinc-finger protein ZFAT | | 分子名称: | ZINC ION, Zinc finger protein ZFAT | | 著者 | Tochio, N, Umehara, T, Kigawa, T, Yokoyama, S. | | 登録日 | 2015-01-26 | | 公開日 | 2015-04-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT
J.Struct.Funct.Genom., 16, 2015
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2RV5
 | | Solution structures of the DNA-binding domain (ZF8) of mouse immune-related zinc-finger protein ZFAT | | 分子名称: | ZINC ION, Zinc finger protein ZFAT | | 著者 | Tochio, N, Umehara, T, Kigawa, T, Yokoyama, S. | | 登録日 | 2015-01-26 | | 公開日 | 2015-04-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT
J.Struct.Funct.Genom., 16, 2015
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2RUW
 | | Solution structures of the DNA-binding domain (ZF5) of immune-related zinc-finger protein ZFAT | | 分子名称: | ZINC ION, Zinc finger protein ZFAT | | 著者 | Tochio, N, Umehara, T, Kigawa, T, Yokoyama, S. | | 登録日 | 2015-01-26 | | 公開日 | 2015-04-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT
J.Struct.Funct.Genom., 16, 2015
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2RV1
 | | Solution structures of the DNA-binding domain (ZF13) of immune-related zinc-finger protein ZFAT | | 分子名称: | ZINC ION, Zinc finger protein ZFAT | | 著者 | Tochio, N, Umehara, T, Kigawa, T, Yokoyama, S. | | 登録日 | 2015-01-26 | | 公開日 | 2015-04-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT
J.Struct.Funct.Genom., 16, 2015
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2RV7
 | | Solution structures of the DNA-binding domains (ZF3-ZF4-ZF5) of immune-related zinc-finger protein ZFAT | | 分子名称: | ZINC ION, Zinc finger protein ZFAT | | 著者 | Tochio, N, Umehara, T, Kigawa, T, Yokoyama, S. | | 登録日 | 2015-01-26 | | 公開日 | 2015-04-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT
J.Struct.Funct.Genom., 16, 2015
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2RUU
 | | Solution structures of the DNA-binding domain (ZF3) of immune-related zinc-finger protein ZFAT | | 分子名称: | ZINC ION, Zinc finger protein ZFAT | | 著者 | Tochio, N, Umehara, T, Kigawa, T, Yokoyama, S. | | 登録日 | 2015-01-26 | | 公開日 | 2015-04-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT
J.Struct.Funct.Genom., 16, 2015
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2RUZ
 | | Solution structures of the DNA-binding domain (ZF11) of immune-related zinc-finger protein ZFAT | | 分子名称: | ZINC ION, Zinc finger protein ZFAT | | 著者 | Tochio, N, Umehara, T, Kigawa, T, Yokoyama, S. | | 登録日 | 2015-01-26 | | 公開日 | 2015-04-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT
J.Struct.Funct.Genom., 16, 2015
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2RSH
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2RSJ
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2RSI
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5B2I
 | | Human nucleosome containing CpG unmethylated DNA | | 分子名称: | DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Fujii, Y, Wakamori, M, Umehara, T, Yokoyama, S. | | 登録日 | 2016-01-16 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of human nucleosome core particle containing enzymatically introduced CpG methylation.
Febs Open Bio, 6, 2016
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3ABU
 | | Crystal Structure of LSD1 in complex with a 2-PCPA derivative, S1201 | | 分子名称: | Lysine-specific histone demethylase 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl (2R,3S,4S)-5-[(1R,3R,3aS)-3-[2-(benzyloxy)-3-fluorophenyl]-1-hydroxy-10,11-dimethyl-4,6-dioxo-2,3,5,6-tetrahydro-1H-benzo[g]pyrrolo[2,1-e]pteridin-8(4H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate | | 著者 | Mimasu, S, Umezawa, N, Sato, S, Higuchi, T, Umehara, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2009-12-21 | | 公開日 | 2010-07-07 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structurally Designed trans-2-Phenylcyclopropylamine Derivatives Potently Inhibit Histone Demethylase LSD1/KDM1
Biochemistry, 49, 2010
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