5YJB

LSD1-CoREST in complex with 4-[5-(piperidin-4-ylmethoxy)-2-(p-tolyl)pyridin-3-yl]benzonitrile

Summary for 5YJB

• Entry DOI: 10.2210/pdb5yjb/pdb
• Descriptor: Lysine-specific histone demethylase 1A, REST corepressor 1, FLAVIN-ADENINE DINUCLEOTIDE, ... (5 entities in total)
• Functional Keywords: demethylase, amine oxidase, chromatin, histone, fad, corepressor, oxidoreductase-transcription-inhibitor complex, oxidoreductase/transcription/inhibitor
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 91537.19

Authors

Niwa, H.,Sato, S.,Hashimoto, T.,Matsuno, K.,Umehara, T. (deposition date: 2017-10-10, release date: 2018-07-04, Last modification date: 2023-11-22)

• Primary citation: Niwa, H.,Sato, S.,Hashimoto, T.,Matsuno, K.,Umehara, T.; Crystal Structure of LSD1 in Complex with 4-[5-(Piperidin-4-ylmethoxy)-2-(p-tolyl)pyridin-3-yl]benzonitrile.; Molecules, 23:-, 2018; PubMed: 29949906; DOI: 10.3390/molecules23071538

Experimental method

X-RAY DIFFRACTION (2.96 Å)