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PDB: 98 件
6IPK
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BU of 6ipk by Molmil
Binary Complex of Human DNA Polymerase Mu with Mn8oxodGTP
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, ...
著者Chang, Y.K, Wu, W.J, Tsai, M.D.
登録日2018-11-03
公開日2019-05-29
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6IPM
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BU of 6ipm by Molmil
Binary Complex of Human DNA Polymerase Mu with MgdCTP
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MAGNESIUM ION, ...
著者Chang, Y.K, Wu, W.J, Tsai, M.D.
登録日2018-11-03
公開日2019-05-29
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6IPF
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BU of 6ipf by Molmil
Post-catalytic Complex of Human DNA Polymerase Mu with Templating Cytosine and Mn-8oxodGMP
分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ...
著者Chang, Y.K, Wu, W.J, Tsai, M.D.
登録日2018-11-03
公開日2019-05-29
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6IPL
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BU of 6ipl by Molmil
Binary Complex of Human DNA Polymerase Mu with MgdATP
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MAGNESIUM ION, ...
著者Chang, Y.K, Wu, W.J, Tsai, M.D.
登録日2018-11-03
公開日2019-05-29
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6IPD
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BU of 6ipd by Molmil
Post-catalytic Complex of Human DNA Polymerase Mu with Templating Adenine and Mn-8oxodGMP
分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA (5'-D(*CP*GP*GP*CP*AP*TP*AP*CP*G)-3'), ...
著者Chang, Y.K, Wu, W.J, Tsai, M.D.
登録日2018-11-03
公開日2019-05-29
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6IPI
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BU of 6ipi by Molmil
Binary Complex of Human DNA Polymerase Mu with MndCTP
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, ...
著者Chang, Y.K, Wu, W.J, Tsai, M.D.
登録日2018-11-03
公開日2019-05-29
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6JD1
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BU of 6jd1 by Molmil
Cryo-EM Structure of Sulfolobus solfataricus ketol-acid reductoisomerase (Sso-KARI) in complex with Mg2+, NADH, and CPD at pH7.5
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, MAGNESIUM ION, Putative ketol-acid reductoisomerase 2, ...
著者Chen, C.Y, Chang, Y.C, Lin, K.F, Huang, C.H, Lin, B.L, Ko, T.P, Hsieh, D.L, Tsai, M.D.
登録日2019-01-30
公開日2019-04-17
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Use of Cryo-EM To Uncover Structural Bases of pH Effect and Cofactor Bispecificity of Ketol-Acid Reductoisomerase.
J. Am. Chem. Soc., 141, 2019
6JCW
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BU of 6jcw by Molmil
Cryo-EM Structure of Sulfolobus solfataricus ketol-acid reductoisomerase (Sso-KARI) with Mg2+ at pH8.5
分子名称: MAGNESIUM ION, ketol-acid reductoisomerase
著者Chen, C.Y, Chang, Y.C, Lin, K.F, Huang, C.H, Lin, B.L, Ko, T.P, Hsieh, D.L, Tsai, M.D.
登録日2019-01-30
公開日2019-04-17
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Use of Cryo-EM To Uncover Structural Bases of pH Effect and Cofactor Bispecificity of Ketol-Acid Reductoisomerase.
J. Am. Chem. Soc., 141, 2019
6JD2
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BU of 6jd2 by Molmil
Crystal structure of Sulfolobus solfataricus ketol-acid reductoisomerase (Sso-KARI) in complex with Mg2+ at pH8.5
分子名称: BETA-MERCAPTOETHANOL, MAGNESIUM ION, Putative ketol-acid reductoisomerase 2
著者Chen, C.Y, Chang, Y.C, Lin, K.F, Huang, C.H, Lin, B.L, Ko, T.P, Hsieh, D.L, Tsai, M.D.
登録日2019-01-30
公開日2019-08-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Use of Cryo-EM To Uncover Structural Bases of pH Effect and Cofactor Bispecificity of Ketol-Acid Reductoisomerase.
J.Am.Chem.Soc., 141, 2019
6JCV
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BU of 6jcv by Molmil
Cryo-EM structure of Sulfolobus solfataricus ketol-acid reductoisomerase (Sso-KARI) with Mg2+ at pH7.5
分子名称: MAGNESIUM ION, Putative ketol-acid reductoisomerase 2
著者Chen, C.Y, Chang, Y.C, Lin, K.F, Huang, C.H, Lin, B.L, Ko, T.P, Hsieh, D.L, Tsai, M.D.
登録日2019-01-30
公開日2019-04-17
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.92 Å)
主引用文献Use of Cryo-EM To Uncover Structural Bases of pH Effect and Cofactor Bispecificity of Ketol-Acid Reductoisomerase.
J. Am. Chem. Soc., 141, 2019
6JCZ
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BU of 6jcz by Molmil
Cryo-EM Structure of Sulfolobus solfataricus ketol-acid reductoisomerase (Sso-KARI) in complex with Mg2+, NADPH, and CPD at pH7.5
分子名称: MAGNESIUM ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative ketol-acid reductoisomerase 2, ...
著者Chen, C.Y, Chang, Y.C, Lin, K.F, Huang, C.H, Lin, B.L, Ko, T.P, Hsieh, D.L, Tsai, M.D.
登録日2019-01-30
公開日2019-04-17
最終更新日2019-05-01
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Use of Cryo-EM To Uncover Structural Bases of pH Effect and Cofactor Bispecificity of Ketol-Acid Reductoisomerase.
J. Am. Chem. Soc., 141, 2019
6IPJ
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BU of 6ipj by Molmil
Binary Complex of Human DNA Polymerase Mu with MndTTP
分子名称: DNA-directed DNA/RNA polymerase mu,DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, SULFATE ION, ...
著者Chang, Y.K, Wu, W.J, Tsai, M.D.
登録日2018-11-03
公開日2019-05-29
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
6KPE
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BU of 6kpe by Molmil
343 K cryoEM structure of Sso-KARI in complex with Mg2+
分子名称: Ketol-acid reductoisomerase, MAGNESIUM ION
著者Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D.
登録日2019-08-15
公開日2020-03-25
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.83 Å)
主引用文献Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions.
J.Am.Chem.Soc., 141, 2019
6KQJ
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BU of 6kqj by Molmil
309 K cryoEM structure of Sso-KARI in complex with Mg2+, NADH and CPD
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Ketol-acid reductoisomerase, MAGNESIUM ION, ...
著者Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D.
登録日2019-08-18
公開日2020-03-25
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.54 Å)
主引用文献Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions.
J.Am.Chem.Soc., 141, 2019
6KOU
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BU of 6kou by Molmil
277 K cryoEM structure of Sso-KARI in complex with magnesium ions
分子名称: Ketol-acid reductoisomerase, MAGNESIUM ION
著者Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D.
登録日2019-08-13
公開日2020-03-25
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.43 Å)
主引用文献Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions.
J.Am.Chem.Soc., 141, 2019
6KQ4
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BU of 6kq4 by Molmil
323 K cryoEM structure of Sso-KARI in complex with Mg2+
分子名称: Ketol-acid reductoisomerase, MAGNESIUM ION
著者Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D.
登録日2019-08-16
公開日2020-03-25
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions.
J.Am.Chem.Soc., 141, 2019
6KPI
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BU of 6kpi by Molmil
298 K cryoEM structure of Sso-KARI in complex with Mg2+
分子名称: Ketol-acid reductoisomerase, MAGNESIUM ION
著者Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D.
登録日2019-08-15
公開日2020-03-25
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.43 Å)
主引用文献Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions.
J.Am.Chem.Soc., 141, 2019
6KPJ
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BU of 6kpj by Molmil
298 K cryoEM structure of Sso-KARI in complex with Mg2+, NADH and CPD
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Ketol-acid reductoisomerase, MAGNESIUM ION, ...
著者Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D.
登録日2019-08-15
公開日2020-03-25
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.56 Å)
主引用文献Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions.
J.Am.Chem.Soc., 141, 2019
6KQ8
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BU of 6kq8 by Molmil
328 K cryoEM structure of Sso-KARI in complex with Mg2+
分子名称: Ketol-acid reductoisomerase, MAGNESIUM ION
著者Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D.
登録日2019-08-16
公開日2020-03-25
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions.
J.Am.Chem.Soc., 141, 2019
6KPA
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BU of 6kpa by Molmil
277 K cryoEM structure of Sso-KARI in complex with Mg2+, NADH and CPD
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Ketol-acid reductoisomerase, MAGNESIUM ION, ...
著者Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D.
登録日2019-08-15
公開日2020-03-25
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.75 Å)
主引用文献Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions.
J.Am.Chem.Soc., 141, 2019
1TR4
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BU of 1tr4 by Molmil
Solution structure of human oncogenic protein gankyrin
分子名称: 26S proteasome non-ATPase regulatory subunit 10
著者Yuan, C, Li, J, Mahajan, A, Poi, M.J, Byeon, I.J, Tsai, M.D.
登録日2004-06-19
公開日2004-11-16
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the human oncogenic protein gankyrin containing seven ankyrin repeats and analysis of its structure--function relationship.
Biochemistry, 43, 2004
1R21
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BU of 1r21 by Molmil
Solution Structure of human Ki67 FHA Domain
分子名称: Antigen Ki-67
著者Byeon, I.J, Li, H, Tsai, M.D.
登録日2003-09-25
公開日2003-12-30
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of Human Ki67 FHA Domain and its Binding to a Phosphoprotein Fragment from hNIFK Reveal Unique Recognition Sites and New Views to the Structural Basis of FHA Domain Functions
J.Mol.Biol., 335, 2004
5YEQ
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BU of 5yeq by Molmil
The structure of Sac-KARI protein
分子名称: 1,2-ETHANEDIOL, Ketol-acid reductoisomerase (NADP(+)), MAGNESIUM ION, ...
著者Ko, T.P, Chen, C.Y, Lin, K.F, Lin, B.L, Huang, C.H, Chiang, C.H, Horng, J.C, Tsai, M.D.
登録日2017-09-19
公開日2018-07-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献NADH/NADPH bi-cofactor-utilizing and thermoactive ketol-acid reductoisomerase from Sulfolobus acidocaldarius
Sci Rep, 8, 2018
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