6WN2
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5JBQ
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6C5B
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![BU of 6c5b by Molmil](/molmil-images/mine/6c5b) | Crystal Structure Analysis of LaPhzM | Descriptor: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, FORMIC ACID, Methyltransferase, ... | Authors: | Beltran, D.G, Schacht, A, Zhang, L. | Deposit date: | 2018-01-15 | Release date: | 2018-03-21 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Functional and Structural Analysis of Phenazine O-Methyltransferase LaPhzM from Lysobacter antibioticus OH13 and One-Pot Enzymatic Synthesis of the Antibiotic Myxin. ACS Chem. Biol., 13, 2018
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4G5G
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![BU of 4g5g by Molmil](/molmil-images/mine/4g5g) | ef-tu (Escherichia coli) complexed with nvp-ldu796 | Descriptor: | Elongation factor Tu 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Palestrant, D. | Deposit date: | 2012-07-17 | Release date: | 2012-12-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Antibiotic optimization and chemical structure stabilization of thiomuracin A. J.Med.Chem., 55, 2012
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3U6B
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![BU of 3u6b by Molmil](/molmil-images/mine/3u6b) | Ef-tu (escherichia coli) in complex with nvp-ldi028 | Descriptor: | Elongation factor Tu 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Palestrant, D.J. | Deposit date: | 2011-10-12 | Release date: | 2012-02-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Antibacterial optimization of 4-aminothiazolyl analogues of the natural product GE2270 A: identification of the cycloalkylcarboxylic acids. J.Med.Chem., 54, 2011
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3U6K
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![BU of 3u6k by Molmil](/molmil-images/mine/3u6k) | Ef-tu (escherichia coli) in complex with nvp-ldk733 | Descriptor: | Elongation factor Tu 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Palestrant, D.J. | Deposit date: | 2011-10-12 | Release date: | 2012-02-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Antibacterial optimization of 4-aminothiazolyl analogues of the natural product GE2270 A: identification of the cycloalkylcarboxylic acids. J.Med.Chem., 54, 2011
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3U2Q
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![BU of 3u2q by Molmil](/molmil-images/mine/3u2q) | EF-Tu (Escherichia coli) in complex with NVP-LFF571 | Descriptor: | Elongation factor Tu 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Palestrant, D.J. | Deposit date: | 2011-10-04 | Release date: | 2012-05-02 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Discovery of LFF571: an investigational agent for Clostridium difficile infection. J.Med.Chem., 55, 2012
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1FCA
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2W8G
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![BU of 2w8g by Molmil](/molmil-images/mine/2w8g) | Aplysia californica AChBP bound to in silico compound 35 | Descriptor: | (3-ENDO,8-ANTI)-8-BENZYL-3-(10,11-DIHYDRO-5H-DIBENZO[A,D][7]ANNULEN-5-YLOXY)-8-AZONIABICYCLO[3.2.1]OCTANE, SOLUBLE ACETYLCHOLINE RECEPTOR | Authors: | Ulens, C, Akdemir, A, Jongejan, A, van Elk, R, Edink, E, Bertrand, S, Perrakis, A, Leurs, R, Smit, A.B, Sixma, T.K, Bertrand, D, de Esch, I.J. | Deposit date: | 2009-01-16 | Release date: | 2009-04-14 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Use of Acetylcholine Binding Protein in the Search for Novel Alpha7 Nicotinic Receptor Ligands. In Silico Docking, Pharmacological Screening, and X- Ray Analysis. J.Med.Chem., 52, 2009
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6DAU
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![BU of 6dau by Molmil](/molmil-images/mine/6dau) | Crystal structure of E33Q and E41Q mutant forms of the spermidine/spermine N-acetyltransferase SpeG from Vibrio cholerae | Descriptor: | GLYCEROL, Spermidine N1-acetyltransferase | Authors: | Filippova, E.V, Minasov, G, Beahan, A, Kulyavtsev, P, Tan, L, Tran, D, Kuhn, M.L, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2018-05-02 | Release date: | 2018-07-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Crystal structure of E33Q and E41Q mutant forms of the spermidine/spermine N-acetyltransferase SpeG from Vibrio cholerae. To be Published
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3S2K
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![BU of 3s2k by Molmil](/molmil-images/mine/3s2k) | Structural basis of Wnt signaling inhibition by Dickkopf binding to LRP5/6. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Ahn, V.E, Chu, M.L.-H, Choi, H.-J, Tran, D, Abo, A, Weis, W.I. | Deposit date: | 2011-05-16 | Release date: | 2011-11-02 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Basis of Wnt Signaling Inhibition by Dickkopf Binding to LRP5/6. Dev.Cell, 21, 2011
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7Q21
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![BU of 7q21 by Molmil](/molmil-images/mine/7q21) | III2-IV2 respiratory supercomplex from Corynebacterium glutamicum | Descriptor: | (1R)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate, (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2S)-1-(hexadecanoyloxy)propan-2-yl (10S)-10-methyloctadecanoate, ... | Authors: | Kovalova, T, Moe, A, Krol, S, Yanofsky, D.J, Bott, M, Sjostrand, D, Rubinstein, J.L, Hogbom, M, Brzezinski, P. | Deposit date: | 2021-10-22 | Release date: | 2022-02-02 | Last modified: | 2022-03-16 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | The respiratory supercomplex from C. glutamicum. Structure, 30, 2022
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5OC0
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![BU of 5oc0 by Molmil](/molmil-images/mine/5oc0) | Structure of E. coli superoxide oxidase | Descriptor: | Cytochrome b561, GLYCEROL, MAGNESIUM ION, ... | Authors: | Lundgren, C.A.K, Sjostrand, D, Biner, O, Bennett, M, von Ballmoos, C, Hogbom, M. | Deposit date: | 2017-06-29 | Release date: | 2018-06-20 | Last modified: | 2018-11-07 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Scavenging of superoxide by a membrane-bound superoxide oxidase. Nat. Chem. Biol., 14, 2018
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6O2Q
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![BU of 6o2q by Molmil](/molmil-images/mine/6o2q) | Acetylated Microtubules | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Eshun-Wilson, L, Zhang, R, Portran, D, Nachury, M.V, Toso, D, Lohr, T, Vendruscolo, M, Bonomi, M, Fraser, J.S, Nogales, E. | Deposit date: | 2019-02-24 | Release date: | 2019-05-22 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Effects of alpha-tubulin acetylation on microtubule structure and stability. Proc.Natl.Acad.Sci.USA, 116, 2019
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6ONU
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![BU of 6onu by Molmil](/molmil-images/mine/6onu) | Complex structure of WhiB1 and region 4 of SigA in P21 space group. | Descriptor: | DI(HYDROXYETHYL)ETHER, IRON/SULFUR CLUSTER, RNA polymerase sigma factor SigA, ... | Authors: | Wan, T, Li, S.R, Beltran, D.G, Schacht, A, Becker, D.C, Zhang, L.M. | Deposit date: | 2019-04-22 | Release date: | 2019-11-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural basis of non-canonical transcriptional regulation by the sigma A-bound iron-sulfur protein WhiB1 in M. tuberculosis. Nucleic Acids Res., 48, 2020
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6O2R
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![BU of 6o2r by Molmil](/molmil-images/mine/6o2r) | Deacetylated Microtubules | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Eshun-Wilson, L, Zhang, R, Portran, D, Nachury, M.V, Toso, D, Lohr, T, Vendruscolo, M, Bonomi, M, Fraser, J.S, Nogales, E. | Deposit date: | 2019-02-24 | Release date: | 2019-05-22 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Effects of alpha-tubulin acetylation on microtubule structure and stability. Proc.Natl.Acad.Sci.USA, 116, 2019
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6ONO
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![BU of 6ono by Molmil](/molmil-images/mine/6ono) | Complex structure of WhiB1 and region 4 of SigA in C2221 space group | Descriptor: | DI(HYDROXYETHYL)ETHER, IRON/SULFUR CLUSTER, RNA polymerase sigma factor SigA, ... | Authors: | Wan, T, Li, S.R, Beltran, D.G, Schacht, A, Becker, D.C, Zhang, L.M. | Deposit date: | 2019-04-22 | Release date: | 2019-11-27 | Last modified: | 2020-01-22 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural basis of non-canonical transcriptional regulation by the sigma A-bound iron-sulfur protein WhiB1 in M. tuberculosis. Nucleic Acids Res., 48, 2020
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5MRI
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![BU of 5mri by Molmil](/molmil-images/mine/5mri) | Crystal structure of the Vps10p domain of human sortilin/NTS3 in complex with Triazolone 18 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Sortilin, ... | Authors: | Andersen, J.L, Strandbygaard, D, Thirup, S. | Deposit date: | 2016-12-23 | Release date: | 2017-05-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The identification of novel acid isostere based inhibitors of the VPS10P family sorting receptor Sortilin. Bioorg. Med. Chem. Lett., 27, 2017
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5MRH
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![BU of 5mrh by Molmil](/molmil-images/mine/5mrh) | Crystal structure of the Vps10p domain of human sortilin/NTS3 in complex with Triazolone 1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(3-methylbutyl)-4~{H}-1,2,3-triazol-5-one, Sortilin, ... | Authors: | Andersen, J.L, Strandbygaard, D, Thirup, S. | Deposit date: | 2016-12-23 | Release date: | 2017-05-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The identification of novel acid isostere based inhibitors of the VPS10P family sorting receptor Sortilin. Bioorg. Med. Chem. Lett., 27, 2017
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6O2T
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![BU of 6o2t by Molmil](/molmil-images/mine/6o2t) | Acetylated Microtubules | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Eshun-Wilson, L, Zhang, R, Portran, D, Nachury, M.V, Toso, D, Lohr, T, Vendruscolo, M, Bonomi, M, Fraser, J.S, Nogales, E. | Deposit date: | 2019-02-24 | Release date: | 2019-05-22 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Effects of alpha-tubulin acetylation on microtubule structure and stability. Proc.Natl.Acad.Sci.USA, 116, 2019
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6O2S
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![BU of 6o2s by Molmil](/molmil-images/mine/6o2s) | Deacetylated Microtubules | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Eshun-Wilson, L, Zhang, R, Portran, D, Nachury, M.V, Toso, D, Lohr, T, Vendruscolo, M, Bonomi, M, Fraser, J.S, Nogales, E. | Deposit date: | 2019-02-24 | Release date: | 2019-05-22 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Effects of alpha-tubulin acetylation on microtubule structure and stability. Proc.Natl.Acad.Sci.USA, 116, 2019
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5NF8
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![BU of 5nf8 by Molmil](/molmil-images/mine/5nf8) | Solution structure of detergent-solubilized Rcf1, a yeast mitochondrial inner membrane protein involved in respiratory Complex III/IV supercomplex formation | Descriptor: | Respiratory supercomplex factor 1, mitochondrial | Authors: | Zhou, S, Pettersson, P, Sjoholm, J, Sjostrand, D, Hogbom, M, Brzezinski, P, Maler, L, Adelroth, P. | Deposit date: | 2017-03-13 | Release date: | 2018-02-28 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of yeast Rcf1, a protein involved in respiratory supercomplex formation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7KUF
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![BU of 7kuf by Molmil](/molmil-images/mine/7kuf) | Transcription activation subcomplex with WhiB7 bound to SigmaAr4-RNAP Beta flap tip chimera and DNA | Descriptor: | DNA (5'-D(*CP*AP*GP*AP*AP*AP*AP*TP*CP*GP*GP*TP*TP*GP*TP*GP*GP*T)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*AP*AP*CP*CP*GP*AP*TP*TP*TP*TP*CP*T)-3'), IRON/SULFUR CLUSTER, ... | Authors: | Wan, T, Horova, M, Beltran, D.G, Li, S.R, Zhang, L.M. | Deposit date: | 2020-11-24 | Release date: | 2021-06-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural insights into the functional divergence of WhiB-like proteins in Mycobacterium tuberculosis. Mol.Cell, 81, 2021
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7KUG
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![BU of 7kug by Molmil](/molmil-images/mine/7kug) | Fe-S cluster-bound transcription activator WhiB7 in complex with the SigmaAr4-RNAP Beta flap tip chimera | Descriptor: | IRON/SULFUR CLUSTER, Probable transcriptional regulator WhiB7, RNA polymerase sigma factor, ... | Authors: | Wan, T, Horova, M, Beltran, D.G, Li, S.R, Zhang, L.M. | Deposit date: | 2020-11-24 | Release date: | 2021-06-30 | Last modified: | 2021-10-06 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural insights into the functional divergence of WhiB-like proteins in Mycobacterium tuberculosis. Mol.Cell, 81, 2021
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6TPU
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![BU of 6tpu by Molmil](/molmil-images/mine/6tpu) | Crystal structures of FNIII domain three and four of the human leucocyte common antigen-related protein, LAR | Descriptor: | CHLORIDE ION, Receptor-type tyrosine-protein phosphatase F | Authors: | Vilstrup, J.P, Thirup, S.S, Simonsen, A, Birkefeldt, T, Strandbygaard, D. | Deposit date: | 2019-12-14 | Release date: | 2020-05-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal and solution structures of fragments of the human leucocyte common antigen-related protein. Acta Crystallogr D Struct Biol, 76, 2020
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