6J7C
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![BU of 6j7c by Molmil](/molmil-images/mine/6j7c) | Crystal structure of proline racemase-like protein from Thermococcus litoralis in complex with proline | 分子名称: | PROLINE, Proline racemase | 著者 | Watanabe, Y, Watanabe, S, Itoh, Y, Watanabe, Y. | 登録日 | 2019-01-17 | 公開日 | 2019-02-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of substrate-bound bifunctional proline racemase/hydroxyproline epimerase from a hyperthermophilic archaeon. Biochem. Biophys. Res. Commun., 511, 2019
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8ANY
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![BU of 8any by Molmil](/molmil-images/mine/8any) | Human mitochondrial ribosome in complex with LRPPRC, SLIRP, A-site, P-site, E-site tRNAs and mRNA | 分子名称: | 1,4-DIAMINOBUTANE, 12S mitochondrial rRNA, 16S mitochondrial rRNA, ... | 著者 | Singh, V, Itoh, Y, Amunts, A. | 登録日 | 2022-08-06 | 公開日 | 2023-08-16 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | 主引用文献 | Structural basis of LRPPRC-SLIRP-dependent translation by the
mitoribosome To Be Published
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8J12
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![BU of 8j12 by Molmil](/molmil-images/mine/8j12) | Cryo-EM structure of the AsCas12f-sgRNA-target DNA ternary complex | 分子名称: | DNA (38-MER), MAGNESIUM ION, RNA (247-MER), ... | 著者 | Hino, T, Omura, N.S, Nakagawa, R, Togashi, T, Takeda, N.S, Hiramoto, T, Tasaka, S, Hirano, H, Tokuyama, T, Uosaki, H, Ishiguro, H, Yamano, H, Ozaki, Y, Motooka, D, Mori, H, Kirita, Y, Kise, Y, Itoh, Y, Matoba, S, Aburatani, H, Yachie, N, Siksnys, V, Ohmori, T, Hoshino, A, Nureki, O. | 登録日 | 2023-04-12 | 公開日 | 2023-09-27 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Minimal and most efficient genome editing Cas enzyme To Be Published
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8J3R
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![BU of 8j3r by Molmil](/molmil-images/mine/8j3r) | Cryo-EM structure of the AsCas12f-HKRA-sgRNAS3-5v7-target DNA | 分子名称: | DNA (37-MER), DNA (38-MER), MAGNESIUM ION, ... | 著者 | Hino, T, Omura, N.S, Nakagawa, R, Togashi, T, Takeda, N.S, Hiramoto, T, Tasaka, S, Hirano, H, Tokuyama, T, Uosaki, H, Ishiguro, H, Yamano, H, Ozaki, Y, Motooka, D, Mori, H, Kirita, Y, Kise, Y, Itoh, Y, Matoba, S, Aburatani, H, Yachie, N, Siksnys, V, Ohmori, T, Hoshino, A, Nureki, O. | 登録日 | 2023-04-18 | 公開日 | 2023-09-27 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Minimal and most efficient genome editing Cas enzyme To Be Published
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8J1J
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![BU of 8j1j by Molmil](/molmil-images/mine/8j1j) | Cryo-EM structure of the AsCas12f-YHAM-sgRNAS3-5v7-target DNA | 分子名称: | DNA (38-MER), MAGNESIUM ION, RNA (118-MER), ... | 著者 | Hino, T, Omura, N.S, Nakagawa, R, Togashi, T, Takeda, N.S, Hiramoto, T, Tasaka, S, Hirano, H, Tokuyama, T, Uosaki, H, Ishiguro, H, Yamano, H, Ozaki, Y, Motooka, D, Mori, H, Kirita, Y, Kise, Y, Itoh, Y, Matoba, S, Aburatani, H, Yachie, N, Siksnys, V, Ohmori, T, Hoshino, A, Nureki, O. | 登録日 | 2023-04-13 | 公開日 | 2023-09-27 | 実験手法 | ELECTRON MICROSCOPY (2.91 Å) | 主引用文献 | Minimal and most efficient genome editing Cas enzyme To Be Published
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7QI6
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![BU of 7qi6 by Molmil](/molmil-images/mine/7qi6) | Human mitochondrial ribosome in complex with mRNA, A/P- and P/E-tRNAs at 2.98 A resolution | 分子名称: | 1,4-DIAMINOBUTANE, 12S mitochondrial rRNA, 16S mitochondrial rRNA, ... | 著者 | Singh, V, Itoh, Y, Amunts, A. | 登録日 | 2021-12-14 | 公開日 | 2023-05-17 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | Structure of mitoribosome reveals mechanism of mRNA binding, tRNA interactions with L1 stalk, roles of cofactors and rRNA modifications. Biorxiv, 2023
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7QI5
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![BU of 7qi5 by Molmil](/molmil-images/mine/7qi5) | Human mitochondrial ribosome in complex with mRNA, A/A-, P/P- and E/E-tRNAs at 2.63 A resolution | 分子名称: | 1,4-DIAMINOBUTANE, 12S mitochondrial rRNA, 16S mitochondrial rRNA, ... | 著者 | Singh, V, Itoh, Y, Amunts, A. | 登録日 | 2021-12-14 | 公開日 | 2023-07-05 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.63 Å) | 主引用文献 | Structure of mitoribosome reveals mechanism of mRNA binding, tRNA interactions with L1 stalk, roles of cofactors and rRNA modifications. Biorxiv, 2023
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7QI4
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![BU of 7qi4 by Molmil](/molmil-images/mine/7qi4) | Human mitochondrial ribosome at 2.2 A resolution (bound to partly built tRNAs and mRNA) | 分子名称: | 1,4-DIAMINOBUTANE, 12S mitochondrial rRNA, 16S mitochondrial rRNA, ... | 著者 | Singh, V, Itoh, Y, Amunts, A. | 登録日 | 2021-12-14 | 公開日 | 2022-07-13 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.21 Å) | 主引用文献 | Structure of mitoribosome reveals mechanism of mRNA binding, tRNA interactions with L1 stalk, roles of cofactors and rRNA modifications. Biorxiv, 2023
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8HIO
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![BU of 8hio by Molmil](/molmil-images/mine/8hio) | Cryo-EM structure of the Cas12m2-crRNA binary complex | 分子名称: | Cas12m2, MAGNESIUM ION, RNA (56-MER), ... | 著者 | Omura, N.S, Nakagawa, R, Wu, Y.W, Sudfeld, C, Warren, V.R, Hirano, H, Kusakizako, T, Kise, Y, Lebbink, H.G.J, Itoh, Y, Oost, V.D.J, Nureki, O. | 登録日 | 2022-11-21 | 公開日 | 2023-04-12 | 最終更新日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | 主引用文献 | Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme. Nat.Struct.Mol.Biol., 30, 2023
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8HHM
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![BU of 8hhm by Molmil](/molmil-images/mine/8hhm) | Cryo-EM structure of the Cas12m2-crRNA-target DNA ternary complex intermediate state | 分子名称: | Cas12m2, DNA (36-MER), MAGNESIUM ION, ... | 著者 | Omura, N.S, Nakagawa, R, Wu, Y.W, Sudfeld, C, Warren, V.R, Hirano, H, Kusakizako, T, Kise, Y, Lebbink, H.G.J, Itoh, Y, Oost, V.D.J, Nureki, O. | 登録日 | 2022-11-16 | 公開日 | 2023-04-12 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme. Nat.Struct.Mol.Biol., 30, 2023
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8HHL
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![BU of 8hhl by Molmil](/molmil-images/mine/8hhl) | Cryo-EM structure of the Cas12m2-crRNA-target DNA full R-loop complex | 分子名称: | Cas12m2, MAGNESIUM ION, NTS (36-MER), ... | 著者 | Omura, N.S, Nakagawa, R, Wu, Y.W, Sudfeld, C, Warren, V.R, Hirano, H, Kusakizako, T, Kise, Y, Lebbink, H.G.J, Itoh, Y, Oost, V.D.J, Nureki, O. | 登録日 | 2022-11-16 | 公開日 | 2023-04-12 | 最終更新日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (2.87 Å) | 主引用文献 | Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme. Nat.Struct.Mol.Biol., 30, 2023
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7QIW
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![BU of 7qiw by Molmil](/molmil-images/mine/7qiw) | Specific features and methylation sites of a plant ribosome. 60S ribosomal subunit. | 分子名称: | 25S rRNA, 5.8S rRNA, 50S ribosomal protein L22, ... | 著者 | Cottilli, P, Itoh, Y, Amunts, A. | 登録日 | 2021-12-16 | 公開日 | 2022-07-13 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.35 Å) | 主引用文献 | Cryo-EM structure and rRNA modification sites of a plant ribosome. Plant Commun., 3, 2022
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7QIZ
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![BU of 7qiz by Molmil](/molmil-images/mine/7qiz) | Specific features and methylation sites of a plant 80S ribosome | 分子名称: | 1,4-DIAMINOBUTANE, 18S, 25S rRNA, ... | 著者 | Cottilli, P, Itoh, Y, Amunts, A. | 登録日 | 2021-12-16 | 公開日 | 2022-08-03 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.38 Å) | 主引用文献 | Cryo-EM structure and rRNA modification sites of a plant ribosome. Plant Commun., 3, 2022
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7QIY
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![BU of 7qiy by Molmil](/molmil-images/mine/7qiy) | Specific features and methylation sites of a plant ribosome. 40S head ribosomal subunit. | 分子名称: | 1,4-DIAMINOBUTANE, 18S rRNA head, 40S head ribosomal protein eS19, ... | 著者 | Cottilli, P, Itoh, Y, Amunts, A. | 登録日 | 2021-12-16 | 公開日 | 2022-06-15 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.58 Å) | 主引用文献 | Cryo-EM structure and rRNA modification sites of a plant ribosome. Plant Commun., 3, 2022
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7QIX
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![BU of 7qix by Molmil](/molmil-images/mine/7qix) | Specific features and methylation sites of a plant ribosome. 40S body ribosomal subunit. | 分子名称: | 18S rRNA body, 30S ribosomal protein S15, chloroplastic, ... | 著者 | Cottilli, P, Itoh, Y, Amunts, A. | 登録日 | 2021-12-16 | 公開日 | 2022-06-15 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.53 Å) | 主引用文献 | Cryo-EM structure and rRNA modification sites of a plant ribosome. Plant Commun., 3, 2022
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6YWX
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![BU of 6ywx by Molmil](/molmil-images/mine/6ywx) | The structure of the mitoribosome from Neurospora crassa with tRNA bound to the E-site | 分子名称: | 16S rRNA, 23S rRNA, 3-hydroxyisobutyryl-CoA hydrolase, ... | 著者 | Amunts, A, Itoh, Y, Naschberger, A. | 登録日 | 2020-04-30 | 公開日 | 2020-11-11 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi. Nat Commun, 11, 2020
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6YW5
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![BU of 6yw5 by Molmil](/molmil-images/mine/6yw5) | The structure of the small subunit of the mitoribosome from Neurospora crassa | 分子名称: | 16S rRNA, 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial, ... | 著者 | Amunts, A, Itoh, Y, Naschberger, A. | 登録日 | 2020-04-29 | 公開日 | 2020-11-11 | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | 主引用文献 | Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi. Nat Commun, 11, 2020
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6YWV
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![BU of 6ywv by Molmil](/molmil-images/mine/6ywv) | The structure of the Atp25 bound assembly intermediate of the mitoribosome from Neurospora crassa | 分子名称: | 23 S rRNA, 50S ribosomal protein L14, 50S ribosomal protein L17, ... | 著者 | Amunts, A, Itoh, Y, Naschberger, A. | 登録日 | 2020-04-30 | 公開日 | 2020-11-11 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi. Nat Commun, 11, 2020
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6YWY
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![BU of 6ywy by Molmil](/molmil-images/mine/6ywy) | The structure of the mitoribosome from Neurospora crassa with bound tRNA at the P-site | 分子名称: | 16S rRNA, 23S rRNA, 3-hydroxyisobutyryl-CoA hydrolase, ... | 著者 | Amunts, A, Itoh, Y, Naschberger, A. | 登録日 | 2020-04-30 | 公開日 | 2020-11-11 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi. Nat Commun, 11, 2020
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6YWE
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![BU of 6ywe by Molmil](/molmil-images/mine/6ywe) | The structure of the mitoribosome from Neurospora crassa in the P/E tRNA bound state | 分子名称: | 16S rRNA, 23S rRNA, 3-hydroxyisobutyryl-CoA hydrolase, ... | 著者 | Amunts, A, Itoh, Y, Naschberger, A. | 登録日 | 2020-04-29 | 公開日 | 2020-11-11 | 実験手法 | ELECTRON MICROSCOPY (2.99 Å) | 主引用文献 | Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi. Nat Commun, 11, 2020
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6YWS
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![BU of 6yws by Molmil](/molmil-images/mine/6yws) | The structure of the large subunit of the mitoribosome from Neurospora crassa | 分子名称: | 50S ribosomal protein L14, 50S ribosomal protein L17, 50S ribosomal protein L24, ... | 著者 | Amunts, A, Itoh, Y, Naschberger, A. | 登録日 | 2020-04-30 | 公開日 | 2020-11-11 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | 主引用文献 | Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi. Nat Commun, 11, 2020
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8WUT
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![BU of 8wut by Molmil](/molmil-images/mine/8wut) | SpCas9-MMLV RT-pegRNA-target DNA complex (initiation) | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), DNA (51-MER), ... | 著者 | Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O. | 登録日 | 2023-10-21 | 公開日 | 2024-06-05 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis for pegRNA-guided reverse transcription by a prime editor. Nature, 631, 2024
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8WUS
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![BU of 8wus by Molmil](/molmil-images/mine/8wus) | SpCas9-MMLV RT-pegRNA-target DNA complex (termination) | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, DNA (40-MER), DNA (5'-D(*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), ... | 著者 | Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O. | 登録日 | 2023-10-21 | 公開日 | 2024-06-05 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis for pegRNA-guided reverse transcription by a prime editor. Nature, 631, 2024
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8YGJ
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![BU of 8ygj by Molmil](/molmil-images/mine/8ygj) | SpCas9-MMLV RT-pegRNA-target DNA complex (elongation 28-nt) | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(P*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), DNA (51-MER), ... | 著者 | Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O. | 登録日 | 2024-02-26 | 公開日 | 2024-06-05 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for pegRNA-guided reverse transcription by a prime editor. Nature, 631, 2024
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8WUV
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![BU of 8wuv by Molmil](/molmil-images/mine/8wuv) | SpCas9-MMLV RT-pegRNA-target DNA complex (elongation 16-nt) | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, DNA (5'-D(*TP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*TP*AP*CP*TP*AP*G)-3'), DNA (50-MER), ... | 著者 | Shuto, Y, Nakagawa, R, Hoki, M, Omura, S.N, Hirano, H, Itoh, Y, Nureki, O. | 登録日 | 2023-10-21 | 公開日 | 2024-06-05 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis for pegRNA-guided reverse transcription by a prime editor. Nature, 631, 2024
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