5DAD
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![BU of 5dad by Molmil](/molmil-images/mine/5dad) | Crystal Structure of Human KEAP1 BTB Domain in Complex with Small Molecule TX64014 | 分子名称: | (6aS,7S,10aS)-8-hydroxy-4-methoxy-2,7,10a-trimethyl-5,6,6a,7,10,10a-hexahydrobenzo[h]quinazoline-9-carbonitrile, Kelch-like ECH-associated protein 1 | 著者 | Huerta, C, Jiang, X, Trevino, I, Bender, C.F, Swinger, K.K, Stoll, V.S, Ferguson, D.A, Thomas, P.J, Probst, B, Dulubova, I, Visnick, M, Wigley, W.C. | 登録日 | 2015-08-19 | 公開日 | 2016-08-10 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding. Biochim.Biophys.Acta, 1860, 2016
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5K9Q
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![BU of 5k9q by Molmil](/molmil-images/mine/5k9q) | Crystal structure of multidonor HV1-18-class broadly neutralizing Influenza A antibody 16.a.26 in complex with A/Hong Kong/1-4-MA21-1/1968 (H3N2) Hemagglutinin | 分子名称: | 16.a.26 Heavy chain, 16.a.26 Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Joyce, M.G, Thomas, P.V, Wheatley, A.K, McDermott, A.B, Mascola, J.R, Kwong, P.D. | 登録日 | 2016-06-01 | 公開日 | 2016-11-30 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.503 Å) | 主引用文献 | Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses. Cell(Cambridge,Mass.), 166, 2016
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5KAN
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![BU of 5kan by Molmil](/molmil-images/mine/5kan) | Crystal structure of multidonor HV1-18-class broadly neutralizing Influenza A antibody 16.g.07 in complex with A/Hong Kong/1-4-MA21-1/1968 (H3N2) Hemagglutinin | 分子名称: | 16.g.07 Heavy chain, 16.g.07 Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Joyce, M.G, Thomas, P.V, Wheatley, A.K, McDermott, A.B, Mascola, J.R, Kwong, P.D. | 登録日 | 2016-06-01 | 公開日 | 2016-11-30 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.785 Å) | 主引用文献 | Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses. Cell(Cambridge,Mass.), 166, 2016
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5KAQ
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![BU of 5kaq by Molmil](/molmil-images/mine/5kaq) | Crystal structure of broadly neutralizing Influenza A antibody 31.a.83 in complex with Hemagglutinin Hong Kong 1968. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 31.A.83 FAB HEAVY CHAIN, ANTIBODY 31.A.83 FAB LIGHT CHAIN, ... | 著者 | Joyce, M.G, Thomas, P.V, Wheatley, A.K, McDermott, A.B, Mascola, J.R, Kwong, P.D. | 登録日 | 2016-06-01 | 公開日 | 2017-02-22 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.514 Å) | 主引用文献 | Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses. Cell, 166, 2016
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5K9K
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![BU of 5k9k by Molmil](/molmil-images/mine/5k9k) | Crystal structure of multidonor HV6-1-class broadly neutralizing Influenza A antibody 56.a.09 in complex with Hemagglutinin Hong Kong 1968. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 56.a.09 Heavy chain, ... | 著者 | Joyce, M.G, Thomas, P.V, Wheatley, A.K, McDermott, A.B, Mascola, J.R, Kwong, P.D. | 登録日 | 2016-05-31 | 公開日 | 2016-12-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.97 Å) | 主引用文献 | Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses. Cell, 166, 2016
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5K9O
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![BU of 5k9o by Molmil](/molmil-images/mine/5k9o) | Crystal structure of multidonor HV1-18+HD3-9 class broadly neutralizing Influenza A antibody 31.b.09 in complex with Hemagglutinin H1 A/California/04/2009 | 分子名称: | 31.b.09 Heavy Fv, 31.b.09 Light Fv, Hemagglutinin, ... | 著者 | Joyce, M.G, Thomas, P.V, Wheatley, A.K, McDermott, A.B, Mascola, J.R, Kwong, P.D. | 登録日 | 2016-06-01 | 公開日 | 2016-12-28 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.387 Å) | 主引用文献 | Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses. Cell, 166, 2016
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5WP9
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![BU of 5wp9 by Molmil](/molmil-images/mine/5wp9) | Structural Basis of Mitochondrial Receptor Binding and Constriction by Dynamin-Related Protein 1 | 分子名称: | Dynamin-1-like protein, MAGNESIUM ION, Mitochondrial dynamics protein MID49, ... | 著者 | Kalia, R, Wang, R.Y.R, Yusuf, A, Thomas, P.V, Agard, D.A, Shaw, J.M, Frost, A. | 登録日 | 2017-08-03 | 公開日 | 2018-06-20 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.22 Å) | 主引用文献 | Structural basis of mitochondrial receptor binding and constriction by DRP1. Nature, 558, 2018
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2XUE
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![BU of 2xue by Molmil](/molmil-images/mine/2xue) | CRYSTAL STRUCTURE OF JMJD3 | 分子名称: | 2-OXOGLUTARIC ACID, FE (III) ION, LYSINE-SPECIFIC DEMETHYLASE 6B, ... | 著者 | Chung, C, Rowland, P, Mosley, J, Thomas, P.J. | 登録日 | 2010-10-19 | 公開日 | 2011-12-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A Selective Jumonji H3K27 Demethylase Inhibitor Modulates the Proinflammatory Macrophage Response Nature, 488, 2012
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5K9J
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![BU of 5k9j by Molmil](/molmil-images/mine/5k9j) | Crystal structure of multidonor HV6-1-class broadly neutralizing Influenza A antibody 56.a.09 isolated following H5 immunization. | 分子名称: | 56.a.09 heavy chain, 56.a.09 light chain, POLYETHYLENE GLYCOL (N=34) | 著者 | Joyce, M.G, Thomas, P.V, Wheatley, A.K, McDermott, A.B, Mascola, J.R, Kwong, P.D. | 登録日 | 2016-05-31 | 公開日 | 2016-07-27 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.904 Å) | 主引用文献 | Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses. Cell, 166, 2016
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5FYJ
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![BU of 5fyj by Molmil](/molmil-images/mine/5fyj) | Crystal Structure at 3.4 A Resolution of Fully Glycosylated HIV-1 Clade G X1193.c1 SOSIP.664 Prefusion Env Trimer in Complex with Broadly Neutralizing Antibodies PGT122, 35O22 and VRC01 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Stewart-Jones, G.B.E, Zhou, T, Thomas, P.V, Kwong, P.D. | 登録日 | 2016-03-08 | 公開日 | 2016-04-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B and G Cell(Cambridge,Mass.), 165, 2016
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5FYK
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![BU of 5fyk by Molmil](/molmil-images/mine/5fyk) | Crystal Structure at 3.7 A Resolution of Fully Glycosylated HIV-1 Clade B JR-FL SOSIP.664 Prefusion Env Trimer in Complex with Broadly Neutralizing Antibodies PGT122, 35O22 and VRC01 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22, ... | 著者 | Stewart-Jones, G.B.E, Zhou, T, Thomas, P.V, Kwong, P.D. | 登録日 | 2016-03-08 | 公開日 | 2016-04-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.107 Å) | 主引用文献 | Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B and G Cell(Cambridge,Mass.), 165, 2016
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5FYL
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![BU of 5fyl by Molmil](/molmil-images/mine/5fyl) | Crystal Structure at 3.7 A Resolution of Fully Glycosylated HIV-1 Clade A BG505 SOSIP.664 Prefusion Env Trimer in Complex with Broadly Neutralizing Antibodies PGT122 and 35O22 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 ANTIBODY FAB HEAVY CHAIN, ... | 著者 | Stewart-Jones, G.B.E, Zhou, T, Thomas, P.V, Kwong, P.D. | 登録日 | 2016-03-08 | 公開日 | 2016-04-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B and G Cell(Cambridge,Mass.), 165, 2016
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4ZO2
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![BU of 4zo2 by Molmil](/molmil-images/mine/4zo2) | AidC, a Dizinc Quorum-Quenching Lactonase | 分子名称: | Acylhomoserine lactonase, ZINC ION | 著者 | Mascarenhas, R, Thomas, P.W, Wu, C.-X, Nocek, B.P, Hoang, Q, Fast, W, Liu, D. | 登録日 | 2015-05-05 | 公開日 | 2015-07-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | 主引用文献 | Structural and Biochemical Characterization of AidC, a Quorum-Quenching Lactonase with Atypical Selectivity. Biochemistry, 54, 2015
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4ZO3
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![BU of 4zo3 by Molmil](/molmil-images/mine/4zo3) | AidC, a Dizinc Quorum-Quenching Lactonase, in complex with a product N-hexnoyl-L-homoserine | 分子名称: | Acylhomoserine lactonase, N-hexanoyl-L-homoserine, ZINC ION | 著者 | Mascarenhas, R, Thomas, P.W, Wu, C.-X, Nocek, B.P, Hoang, Q, Fast, W, Liu, D. | 登録日 | 2015-05-05 | 公開日 | 2015-07-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Structural and Biochemical Characterization of AidC, a Quorum-Quenching Lactonase with Atypical Selectivity. Biochemistry, 54, 2015
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1RNC
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![BU of 1rnc by Molmil](/molmil-images/mine/1rnc) | NEWLY OBSERVED BINDING MODE IN PANCREATIC RIBONUCLEASE | 分子名称: | GUANOSINE-5'-MONOPHOSPHATE, RIBONUCLEASE A, SULFATE ION | 著者 | Aguilar, C.F, Thomas, P.J, Mills, A, Moss, D.S, Palmer, R.A. | 登録日 | 1991-10-21 | 公開日 | 1994-01-31 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Newly observed binding mode in pancreatic ribonuclease. J.Mol.Biol., 224, 1992
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1RND
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![BU of 1rnd by Molmil](/molmil-images/mine/1rnd) | NEWLY OBSERVED BINDING MODE IN PANCREATIC RIBONUCLEASE | 分子名称: | 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, RIBONUCLEASE A, SULFATE ION | 著者 | Aguilar, C.F, Thomas, P.J, Mills, A, Moss, D.S, Palmer, R.A. | 登録日 | 1991-10-21 | 公開日 | 1994-01-31 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Newly observed binding mode in pancreatic ribonuclease. J.Mol.Biol., 224, 1992
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4J5H
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![BU of 4j5h by Molmil](/molmil-images/mine/4j5h) | Crystal Structure of B. thuringiensis AiiA mutant F107W with N-decanoyl-L-homoserine bound at the active site | 分子名称: | GLYCEROL, N-acyl homoserine lactonase, N-decanoyl-L-homoserine, ... | 著者 | Liu, C.F, Liu, D, Momb, J, Thomas, P.W, Lajoie, A, Petsko, G.A, Fast, W, Ringe, D. | 登録日 | 2013-02-08 | 公開日 | 2013-06-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | A phenylalanine clamp controls substrate specificity in the quorum-quenching metallo-gamma-lactonase from Bacillus thuringiensis. Biochemistry, 52, 2013
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3DHC
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![BU of 3dhc by Molmil](/molmil-images/mine/3dhc) | 1.3 Angstrom Structure of N-Acyl Homoserine Lactone Hydrolase with the Product N-Hexanoyl-L-Homocysteine Bound to The catalytic Metal Center | 分子名称: | GLYCEROL, N-Acyl Homoserine Lactone Hydrolase, N-hexanoyl-L-homocysteine, ... | 著者 | Liu, D, Momb, J, Thomas, P.W, Moulin, A, Petsko, G.A, Fast, W, Ringe, D. | 登録日 | 2008-06-17 | 公開日 | 2008-07-29 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Mechanism of the quorum-quenching lactonase (AiiA) from Bacillus thuringiensis. 1. Product-bound structures. Biochemistry, 47, 2008
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3DHA
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![BU of 3dha by Molmil](/molmil-images/mine/3dha) | An Ultral High Resolution Structure of N-Acyl Homoserine Lactone Hydrolase with the Product N-Hexanoyl-L-Homoserine Bound at An Alternative Site | 分子名称: | GLYCEROL, N-Acyl Homoserine Lactone Hydrolase, N-hexanoyl-L-homoserine, ... | 著者 | Liu, D, Momb, J, Thomas, P.W, Moulin, A, Petsko, G.A, Fast, W, Ringe, D. | 登録日 | 2008-06-17 | 公開日 | 2008-07-29 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | 主引用文献 | Mechanism of the quorum-quenching lactonase (AiiA) from Bacillus thuringiensis. 1. Product-bound structures. Biochemistry, 47, 2008
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1XF9
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![BU of 1xf9 by Molmil](/molmil-images/mine/1xf9) | Structure of NBD1 from murine CFTR- F508S mutant | 分子名称: | ACETIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, ... | 著者 | Thibodeau, P.H, Brautigam, C.A, Machius, M, Thomas, P.J. | 登録日 | 2004-09-14 | 公開日 | 2004-12-28 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Side chain and backbone contributions of Phe508 to CFTR folding. Nat.Struct.Mol.Biol., 12, 2005
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4J5F
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![BU of 4j5f by Molmil](/molmil-images/mine/4j5f) | Crystal Structure of B. thuringiensis AiiA mutant F107W | 分子名称: | GLYCEROL, N-acyl homoserine lactonase, ZINC ION | 著者 | Liu, C.F, Liu, D, Momb, J, Thomas, P.W, Lajoie, A, Petsko, G.A, Fast, W, Ringe, D. | 登録日 | 2013-02-08 | 公開日 | 2013-06-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | A phenylalanine clamp controls substrate specificity in the quorum-quenching metallo-gamma-lactonase from Bacillus thuringiensis. Biochemistry, 52, 2013
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3DHB
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![BU of 3dhb by Molmil](/molmil-images/mine/3dhb) | 1.4 Angstrom Structure of N-Acyl Homoserine Lactone Hydrolase with the Product N-Hexanoyl-L-Homoserine Bound at The Catalytic Metal Center | 分子名称: | GLYCEROL, N-Acyl Homoserine Lactone Hydrolase, N-hexanoyl-L-homoserine, ... | 著者 | Liu, D, Momb, J, Thomas, P.W, Moulin, A, Petsko, G.A, Fast, W, Ringe, D. | 登録日 | 2008-06-17 | 公開日 | 2008-07-29 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Mechanism of the quorum-quenching lactonase (AiiA) from Bacillus thuringiensis. 1. Product-bound structures. Biochemistry, 47, 2008
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2R2D
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![BU of 2r2d by Molmil](/molmil-images/mine/2r2d) | Structure of a quorum-quenching lactonase (AiiB) from Agrobacterium tumefaciens | 分子名称: | GLYCEROL, PHOSPHATE ION, ZINC ION, ... | 著者 | Liu, D, Thomas, P.W, Momb, J, Hoang, Q, Petsko, G.A, Ringe, D, Fast, W. | 登録日 | 2007-08-24 | 公開日 | 2007-10-09 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure and specificity of a quorum-quenching lactonase (AiiB) from Agrobacterium tumefaciens. Biochemistry, 46, 2007
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1XFA
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![BU of 1xfa by Molmil](/molmil-images/mine/1xfa) | Structure of NBD1 from murine CFTR- F508R mutant | 分子名称: | ACETIC ACID, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... | 著者 | Thibodeau, P.H, Brautigam, C.A, Machius, M, Thomas, P.J. | 登録日 | 2004-09-14 | 公開日 | 2004-12-28 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Side chain and backbone contributions of Phe508 to CFTR folding. Nat.Struct.Mol.Biol., 12, 2005
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6OVZ
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![BU of 6ovz by Molmil](/molmil-images/mine/6ovz) | Crystal structure of the New Delhi metallo-beta-lactamase-1 adduct with a lysine-targeted affinity label | 分子名称: | Beta-lactamase, CALCIUM ION, ZINC ION, ... | 著者 | Monzingo, A.F, Fast, W, Thomas, P.W. | 登録日 | 2019-05-08 | 公開日 | 2019-06-12 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.017 Å) | 主引用文献 | A Lysine-Targeted Affinity Label for Serine-beta-Lactamase Also Covalently Modifies New Delhi Metallo-beta-lactamase-1 (NDM-1). Biochemistry, 58, 2019
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