7ARE
 
 | | DNA origami pointer object v2 | | 分子名称: | SCAFFOLD STRAND, STAPLE STRAND | | 著者 | Thomas, M, Feigl, E, Kohler, F, Kube, M, Nagel-Yuksel, B, Willner, E.M, Funke, J.J, Gerling, T, Stommer, P, Honemann, M.N, Martin, T.G, Scheres, S.H.W, Dietz, H. | | 登録日 | 2020-10-24 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (7.4 Å) | | 主引用文献 | Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution.
Nat Commun, 11, 2020
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1B97
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1B96
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1B95
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1B94
 | | RESTRICTION ENDONUCLEASE ECORV WITH CALCIUM | | 分子名称: | CALCIUM ION, DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3'), RESTRICTION ENDONUCLEASE ECORV | | 著者 | Thomas, M.P, Halford, S.E, Brady, R.L. | | 登録日 | 1999-02-19 | | 公開日 | 1999-02-26 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural analysis of a mutational hot-spot in the EcoRV restriction endonuclease: a catalytic role for a main chain carbonyl group.
Nucleic Acids Res., 27, 1999
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6BG0
 | | Caspase-3 Mutant - D9A,D28A,S150D | | 分子名称: | AC-ASP-GLU-VAL-ASP-CMK, AZIDE ION, Caspase-3, ... | | 著者 | Thomas, M.E, Grinshpon, R, Swartz, P.D, Clark, A.C. | | 登録日 | 2017-10-27 | | 公開日 | 2018-02-21 | | 最終更新日 | 2018-04-25 | | 実験手法 | X-RAY DIFFRACTION (2.125 Å) | | 主引用文献 | Modifications to a common phosphorylation network provide individualized control in caspases.
J. Biol. Chem., 293, 2018
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6BFO
 | | Caspase-3 Mutant- T245D | | 分子名称: | AC-ASP-GLU-VAL-ASP-CMK, AZIDE ION, Caspase-3, ... | | 著者 | Thomas, M.E, Grinshpon, R, Swartz, P.D, Clark, A.C. | | 登録日 | 2017-10-26 | | 公開日 | 2018-02-21 | | 最終更新日 | 2018-04-25 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Modifications to a common phosphorylation network provide individualized control in caspases.
J. Biol. Chem., 293, 2018
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6BG4
 | | Caspase-3 Mutant- T152D | | 分子名称: | AC-ASP-GLU-VAL-ASP-CMK, AZIDE ION, CHLORIDE ION, ... | | 著者 | Thomas, M.E, Grinshpon, R, Swartz, P.D, Clark, A.C. | | 登録日 | 2017-10-27 | | 公開日 | 2018-02-21 | | 最終更新日 | 2018-04-25 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Modifications to a common phosphorylation network provide individualized control in caspases.
J. Biol. Chem., 293, 2018
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6BFK
 | | Caspase-3 Mutant- T245A | | 分子名称: | AC-ASP-GLU-VAL-ASP-CMK, Caspase-3, SODIUM ION | | 著者 | Thomas, M.E, Grinshpon, R, Swartz, P.D, Clark, A.C. | | 登録日 | 2017-10-26 | | 公開日 | 2018-02-21 | | 最終更新日 | 2018-04-25 | | 実験手法 | X-RAY DIFFRACTION (1.753 Å) | | 主引用文献 | Modifications to a common phosphorylation network provide individualized control in caspases.
J. Biol. Chem., 293, 2018
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6BH9
 | | Caspase-3 Mutant - T152A | | 分子名称: | Ac-Asp-Glu-Val-Asp-CMK, CHLORIDE ION, Caspase-3, ... | | 著者 | Thomas, M.E, Grinshpon, R, Swartz, P.D, Clark, A.C. | | 登録日 | 2017-10-30 | | 公開日 | 2018-02-21 | | 最終更新日 | 2018-04-25 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Modifications to a common phosphorylation network provide individualized control in caspases.
J. Biol. Chem., 293, 2018
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6BGQ
 | | Caspase-3 Mutant - S150D | | 分子名称: | AZIDE ION, Ac-Asp-Glu-Val-Asp-CMK, CHLORIDE ION, ... | | 著者 | Thomas, M.E, Grinshpon, R, Swartz, P.D, Clark, A.C. | | 登録日 | 2017-10-29 | | 公開日 | 2018-02-21 | | 最終更新日 | 2018-04-25 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Modifications to a common phosphorylation network provide individualized control in caspases.
J. Biol. Chem., 293, 2018
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6BGK
 | | Caspase-3 Mutant- D9A,D28A,T152D | | 分子名称: | ACE-ASP-GLU-VAL-ASP-0QE, AZIDE ION, CHLORIDE ION, ... | | 著者 | Thomas, M.E, Grinshpon, R, Swartz, P.D, Clark, A.C. | | 登録日 | 2017-10-28 | | 公開日 | 2018-02-21 | | 最終更新日 | 2018-04-25 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Modifications to a common phosphorylation network provide individualized control in caspases.
J. Biol. Chem., 293, 2018
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6BFJ
 | | Caspase-3 Mutant - T245D,S249D | | 分子名称: | AZIDE ION, Ac-Asp-Glu-Val-Asp-CMK, Caspase-3 | | 著者 | Thomas, M.E, Grinshpon, R, Swartz, P.D, Clark, A.C. | | 登録日 | 2017-10-26 | | 公開日 | 2018-02-21 | | 最終更新日 | 2018-04-25 | | 実験手法 | X-RAY DIFFRACTION (1.543 Å) | | 主引用文献 | Modifications to a common phosphorylation network provide individualized control in caspases.
J. Biol. Chem., 293, 2018
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6BFL
 | | Caspase-3 Mutant- D9A,D28A,T245D | | 分子名称: | AC-ASP-GLU-VAL-ASP-CMK, AZIDE ION, Caspase-3 | | 著者 | Thomas, M.E, Grinshpon, R, Swartz, P.D, Clark, A.C. | | 登録日 | 2017-10-26 | | 公開日 | 2018-02-21 | | 最終更新日 | 2018-04-25 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Modifications to a common phosphorylation network provide individualized control in caspases.
J. Biol. Chem., 293, 2018
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6BDV
 | | Crystal structure of Caspase 3 S150A | | 分子名称: | AZIDE ION, Acetyl-Asp-Glu-Val-Asp-CMK, CHLORIDE ION, ... | | 著者 | Thomas, M.E, Grinshpon, R, Swartz, P.D, Clark, A.C. | | 登録日 | 2017-10-24 | | 公開日 | 2018-02-14 | | 最終更新日 | 2018-04-25 | | 実験手法 | X-RAY DIFFRACTION (1.938 Å) | | 主引用文献 | Modifications to a common phosphorylation network provide individualized control in caspases.
J. Biol. Chem., 293, 2018
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6BG1
 | | Caspase-3 Mutant - D9A,D28A,S150E | | 分子名称: | AC-ASP-GLU-VAL-ASP-CMK, Caspase-3, SODIUM ION | | 著者 | Thomas, M.E, Grinshpon, R, Swartz, P.D, Clark, A.C. | | 登録日 | 2017-10-27 | | 公開日 | 2018-02-21 | | 最終更新日 | 2018-04-25 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Modifications to a common phosphorylation network provide individualized control in caspases.
J. Biol. Chem., 293, 2018
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6BGR
 | | Caspase-3 Mutant - S150E | | 分子名称: | AZIDE ION, Ac-Asp-Glu-Val-Asp-CMK, Caspase-3 | | 著者 | Thomas, M.E, Grinshpon, R, Swartz, P.D, Clark, A.C. | | 登録日 | 2017-10-29 | | 公開日 | 2018-02-21 | | 最終更新日 | 2018-04-25 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | Modifications to a common phosphorylation network provide individualized control in caspases.
J. Biol. Chem., 293, 2018
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6BGS
 | | Caspase-3 Mutant - S150Y | | 分子名称: | Ac-Asp-Glu-Val-Asp-CMK, Caspase-3 | | 著者 | Thomas, M.E, Grinshpon, R, Swartz, P.D, Clark, A.C. | | 登録日 | 2017-10-29 | | 公開日 | 2018-02-21 | | 最終更新日 | 2018-04-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Modifications to a common phosphorylation network provide individualized control in caspases.
J. Biol. Chem., 293, 2018
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6BHA
 | | Caspase-3 Mutant - T152V | | 分子名称: | Ac-Asp-Glu-Val-Asp-CMK, Caspase-3 | | 著者 | Thomas, M.E, Grinshpon, R, Swartz, P.D, Clark, A.C. | | 登録日 | 2017-10-30 | | 公開日 | 2018-02-21 | | 最終更新日 | 2018-04-25 | | 実験手法 | X-RAY DIFFRACTION (1.603 Å) | | 主引用文献 | Modifications to a common phosphorylation network provide individualized control in caspases.
J. Biol. Chem., 293, 2018
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6CWS
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6XVK
 | | Crystal structure of the KDR (VEGFR2) kinase domain in complex with a type-II inhibitor bearing an acrylamide | | 分子名称: | Vascular endothelial growth factor receptor 2, ~{N}-(4,4-dimethyl-2-prop-1-ynyl-3,1-benzoxazin-6-yl)-2-[3-methoxy-5-(7-methoxyquinolin-4-yl)oxy-pyridin-2-yl]ethanamide | | 著者 | Schimpl, M, McAuley, K, Hoyt, E.A, Thomas, M, Bodnarchuk, M.S, Lewis, H.J, Barratt, D, Deery, M.J, Ogg, D.J, Bernardes, G.J.L, Ward, R.A, Kettle, J.G, Waring, M.J. | | 登録日 | 2020-01-22 | | 公開日 | 2020-05-27 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Alkynyl Benzoxazines and Dihydroquinazolines as Cysteine Targeting Covalent Warheads and Their Application in Identification of Selective Irreversible Kinase Inhibitors.
J.Am.Chem.Soc., 142, 2020
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6XVA
 | | Crystal structure of the kinase domain of human c-KIT in complex with a type-II inhibitor bearing an acrylamide | | 分子名称: | Mast/stem cell growth factor receptor Kit,Mast/stem cell growth factor receptor Kit, ~{N}-[[3-[2-[3-methoxy-5-(7-methoxyquinolin-4-yl)oxy-pyridin-2-yl]ethanoylamino]-5-methyl-phenyl]methyl]propanamide | | 著者 | Schimpl, M, McAuley, K, Hoyt, E.A, Thomas, M, Bodnarchuk, M.S, Lewis, H.J, Barratt, D, Deery, M.J, Ogg, D.J, Bernardes, G.J.L, Ward, R.A, Kettle, J.G, Waring, M.J. | | 登録日 | 2020-01-21 | | 公開日 | 2020-05-27 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Alkynyl Benzoxazines and Dihydroquinazolines as Cysteine Targeting Covalent Warheads and Their Application in Identification of Selective Irreversible Kinase Inhibitors.
J.Am.Chem.Soc., 142, 2020
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6XV9
 | | Crystal structure of the kinase domain of human c-KIT in complex with a type-II inhibitor | | 分子名称: | Mast/stem cell growth factor receptor Kit,Mast/stem cell growth factor receptor Kit, ~{N}-[3-[(dimethylamino)methyl]-5-methyl-phenyl]-2-[3-methoxy-5-(7-methoxyquinolin-4-yl)oxy-pyridin-2-yl]ethanamide | | 著者 | Ogg, D.J, Howard, T, McAuley, K, Hoyt, E.A, Thomas, M, Bodnarchuk, M.S, Lewis, H.J, Barratt, D, Deery, M.J, Bernardes, G.J.L, Ward, R.A, Kettle, J.G, Waring, M.J. | | 登録日 | 2020-01-21 | | 公開日 | 2020-05-27 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3.38 Å) | | 主引用文献 | Alkynyl Benzoxazines and Dihydroquinazolines as Cysteine Targeting Covalent Warheads and Their Application in Identification of Selective Irreversible Kinase Inhibitors.
J.Am.Chem.Soc., 142, 2020
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6XVB
 | | Crystal structure of the kinase domain of human c-KIT with a cyclic imidate inhibitor covalently bound to Cys788 | | 分子名称: | Mast/stem cell growth factor receptor Kit,Mast/stem cell growth factor receptor Kit, ~{N}-(4,4-dimethyl-2-propyl-3,1-benzoxazin-6-yl)-2-[3-methoxy-5-(7-methoxyquinolin-4-yl)oxy-pyridin-2-yl]ethanamide | | 著者 | Schimpl, M, McAuley, K, Hoyt, E.A, Thomas, M, Bodnarchuk, M.S, Lewis, H.J, Barratt, D, Deery, M.J, Ogg, D.J, Bernardes, G.J.L, Ward, R.A, Kettle, J.G, Waring, M.J. | | 登録日 | 2020-01-21 | | 公開日 | 2020-05-27 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Alkynyl Benzoxazines and Dihydroquinazolines as Cysteine Targeting Covalent Warheads and Their Application in Identification of Selective Irreversible Kinase Inhibitors.
J.Am.Chem.Soc., 142, 2020
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6H8F
 | | Fragment of the C-terminal domain of the TssA component of the type VI secretion system from Burkholderia cenocepacia | | 分子名称: | TssA | | 著者 | Dix, S.R, Owen, H.J, Sun, R, Ahmad, A, Shastri, S, Spiewak, H.L, Mosby, D.J, Harris, M.J, Batters, S.L, Brooker, T.A, Tzokov, S.B, Sedelnikova, S.E, Baker, P.J, Bullough, P.A, Rice, D.W, Thomas, M.S. | | 登録日 | 2018-08-02 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Structural insights into the function of type VI secretion system TssA subunits.
Nat Commun, 9, 2018
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