6BG0
Caspase-3 Mutant - D9A,D28A,S150D
Summary for 6BG0
Entry DOI | 10.2210/pdb6bg0/pdb |
Related PRD ID | PRD_000238 |
Descriptor | Caspase-3, AC-ASP-GLU-VAL-ASP-CMK, SODIUM ION, ... (6 entities in total) |
Functional Keywords | allosteric regulation; apoptosis; biophysics; caspase; computational biology; x-ray crystallography; fluorescence; molecular dynamics; protein evolution, apoptosis, apoptosis-inhibitor complex, apoptosis/inhibitor |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm: P42574 P42574 |
Total number of polymer chains | 6 |
Total formula weight | 64461.81 |
Authors | Thomas, M.E.,Grinshpon, R.,Swartz, P.D.,Clark, A.C. (deposition date: 2017-10-27, release date: 2018-02-21, Last modification date: 2018-04-25) |
Primary citation | Thomas, M.E.,Grinshpon, R.,Swartz, P.,Clark, A.C. Modifications to a common phosphorylation network provide individualized control in caspases. J. Biol. Chem., 293:5447-5461, 2018 Cited by PubMed: 29414778DOI: 10.1074/jbc.RA117.000728 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.125 Å) |
Structure validation
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