6BG0
Caspase-3 Mutant - D9A,D28A,S150D
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Caspase-3 | polymer | 175 | 19699.3 | 2 | UniProt (P42574) Pfam (PF00656) In PDB | Homo sapiens (Human) | CASP-3,Apopain,Cysteine protease CPP32,CPP-32,Protein Yama,SREBP cleavage activity 1,SCA-1 |
| 2 | C, D | Caspase-3 | polymer | 102 | 11910.6 | 2 | UniProt (P42574) Pfam (PF00656) In PDB | Homo sapiens (Human) | CASP-3,Apopain,Cysteine protease CPP32,CPP-32,Protein Yama,SREBP cleavage activity 1,SCA-1 |
| 3 | G, F | AC-ASP-GLU-VAL-ASP-CMK | polymer | 6 | 534.9 | 2 | BIRD (PRD_000238) | Homo sapiens | |
| 4 | A, B | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | C, B, G | AZIDE ION | non-polymer | 42.0 | 3 | Chemie (AZI) | |||
| 6 | water | water | 18.0 | 346 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 175 (UniProt: P42574)
| PDB | External Database | Details |
|---|---|---|
| Ala 9 | Asp 9 | engineered mutation |
| Ala 28 | Asp 28 | engineered mutation |
| Asp 150 | Ser 150 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 64289.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 172.0 | |
| All* | Total formula weight | 64461.8 |
