5M1H
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4JMR
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![BU of 4jmr by Molmil](/molmil-images/mine/4jmr) | A unique spumavirus gag N-terminal domain with functional properties of orthoretroviral Matrix and Capsid | Descriptor: | Env protein, Gag protein | Authors: | Taylor, I.A, Goldstone, D.C, Flower, T.G, Ball, N.J. | Deposit date: | 2013-03-14 | Release date: | 2013-05-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A Unique Spumavirus Gag N-terminal Domain with Functional Properties of Orthoretroviral Matrix and Capsid. Plos Pathog., 9, 2013
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4JNH
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1MB1
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![BU of 1mb1 by Molmil](/molmil-images/mine/1mb1) | MBP1 FROM SACCHAROMYCES CEREVISIAE | Descriptor: | MLU1-BOX BINDING PROTEIN | Authors: | Taylor, I.A, Smerdon, S.J. | Deposit date: | 1997-07-23 | Release date: | 1998-07-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The X-ray structure of the DNA-binding domain from the Saccharomyces cerevisiae cell-cycle transcription factor Mbp1 at 2.1 A resolution. J.Mol.Biol., 272, 1997
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6XU1
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![BU of 6xu1 by Molmil](/molmil-images/mine/6xu1) | Crystal structure of tetrameric human H215A-SAMHD1 (residues 109-626) with GTP, dAMPNPP and Mg | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, FE (III) ION, ... | Authors: | Morris, E.R, Kunzelmann, S, Caswell, S.J, Arnold, L.H, Purkiss, A.G, Kelly, G, Taylor, I.A. | Deposit date: | 2020-01-17 | Release date: | 2020-06-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis. Nat Commun, 11, 2020
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4UX5
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![BU of 4ux5 by Molmil](/molmil-images/mine/4ux5) | Structure of DNA complex of PCG2 | Descriptor: | 5'-D(*CP*AP*AP*TP*GP*AP*CP*GP*CP*GP*TP*AP*AP*GP)-3', 5'-D(*CP*TP*TP*AP*CP*GP*CP*GP*TP*CP*AP*TP*TP*GP)-3', TRANSCRIPTION FACTOR MBP1 | Authors: | Liu, J, Huang, J, Zhao, Y, Liu, H, Wang, D, Yang, J, Zhao, W, Taylor, I.A, Peng, Y. | Deposit date: | 2014-08-19 | Release date: | 2015-01-14 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Basis of DNA Recognition by Pcg2 Reveals a Novel DNA Binding Mode for Winged Helix-Turn-Helix Domains. Nucleic Acids Res., 43, 2015
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5Z1V
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![BU of 5z1v by Molmil](/molmil-images/mine/5z1v) | Crystal structure of AvrPib | Descriptor: | AvrPib protein | Authors: | Zhang, X, He, D, Zhao, Y.X, Taylor, I.A, Peng, Y.L, Yang, J, Liu, J.F. | Deposit date: | 2017-12-28 | Release date: | 2018-09-05 | Last modified: | 2018-10-03 | Method: | X-RAY DIFFRACTION (1.661 Å) | Cite: | A positive-charged patch and stabilized hydrophobic core are essential for avirulence function of AvrPib in the rice blast fungus. Plant J., 96, 2018
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6ZUE
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7A5Y
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![BU of 7a5y by Molmil](/molmil-images/mine/7a5y) | Crystal structure of tetrameric human H215A-SAMHD1 (residues 109-626) with Rp-dGTP-alphaS (T8T) and Mg | Descriptor: | 2'-deoxyguanosine-5'-O-(1-thiotriphosphate), Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, FE (III) ION, ... | Authors: | Morris, E.R, Kunzelmann, S, Caswell, S.J, Purkiss, A, Taylor, I.A. | Deposit date: | 2020-08-24 | Release date: | 2021-05-26 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Probing the Catalytic Mechanism and Inhibition of SAMHD1 Using the Differential Properties of R p - and S p -dNTP alpha S Diastereomers. Biochemistry, 60, 2021
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7ZUD
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![BU of 7zud by Molmil](/molmil-images/mine/7zud) | Crystal structure of HIV-1 capsid IP6-CPSF6 complex | Descriptor: | Capsid protein p24, Cleavage and polyadenylation specificity factor subunit 6, INOSITOL HEXAKISPHOSPHATE | Authors: | Nicastro, G, Taylor, I.A. | Deposit date: | 2022-05-12 | Release date: | 2022-07-27 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.93 Å) | Cite: | CP-MAS and Solution NMR Studies of Allosteric Communication in CA-assemblies of HIV-1. J.Mol.Biol., 434, 2022
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6TXA
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![BU of 6txa by Molmil](/molmil-images/mine/6txa) | Crystal structure of tetrameric human D137N-SAMHD1 (residues 109-626) with XTP, dGMPNPP and Mg | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, FE (III) ION, ... | Authors: | Morris, E.R, Kunzelmann, S, Caswell, S.J, Arnold, L.H, Purkiss, A, Kelly, G, Taylor, I.A. | Deposit date: | 2020-01-13 | Release date: | 2020-06-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.853 Å) | Cite: | Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis. Nat Commun, 11, 2020
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6TXE
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![BU of 6txe by Molmil](/molmil-images/mine/6txe) | Crystal structure of tetrameric human wt-SAMHD1 (residues 109-626) with GTP, dATP, dTMPNPP and Mg | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ... | Authors: | Morris, E.R, Kunzelmann, S, Caswell, S.J, Arnold, L.H, Purkiss, A.G, Kelly, G, Taylor, I.A. | Deposit date: | 2020-01-14 | Release date: | 2020-06-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis. Nat Commun, 11, 2020
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5M1G
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6ES4
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![BU of 6es4 by Molmil](/molmil-images/mine/6es4) | A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets | Descriptor: | 1,2-ETHANEDIOL, SULFATE ION, Syncrip, ... | Authors: | Hobor, F, Dallmann, A, Ball, N.J, Cicchini, C, Battistelli, C, Ogrodowicz, R.W, Christodoulou, E, Martin, S.R, Castello, A, Tripodi, M, Taylor, I.A, Ramos, A. | Deposit date: | 2017-10-19 | Release date: | 2018-03-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets. Nat Commun, 9, 2018
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7NLG
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7NLI
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7NLH
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2V4X
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![BU of 2v4x by Molmil](/molmil-images/mine/2v4x) | Crystal Structure of Jaagsiekte Sheep Retrovirus Capsid N-terminal domain | Descriptor: | CAPSID PROTEIN P27 | Authors: | Mortuza, G.B, Goldstone, D.C, Pashley, C, Haire, L.F, Palmarini, M, Taylor, W.R, Stoye, J.P, Taylor, I.A. | Deposit date: | 2008-09-30 | Release date: | 2008-11-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of the Capsid Amino-Terminal Domain from the Betaretrovirus, Jaagsiekte Sheep Retrovirus. J.Mol.Biol., 386, 2009
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6YOM
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![BU of 6yom by Molmil](/molmil-images/mine/6yom) | Crystal structure of tetrameric human D137N-SAMHD1 (residues 109-626) with XTP, dATP, dCMPNPP, Mn and Mg | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ... | Authors: | Morris, E.R, Kunzelmann, S, Caswell, S.J, Arnold, L.H, Purkiss, A.G, Kelly, G, Taylor, I.A. | Deposit date: | 2020-04-14 | Release date: | 2020-06-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis. Nat Commun, 11, 2020
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2ASB
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![BU of 2asb by Molmil](/molmil-images/mine/2asb) | Structure of a Mycobacterium tuberculosis NusA-RNA complex | Descriptor: | Transcription elongation protein nusA, ribosomal RNA (5'- GAACUCAAUAG -3') | Authors: | Beuth, B, Pennell, S, Arnvig, K.B, Martin, S.R, Taylor, I.A. | Deposit date: | 2005-08-23 | Release date: | 2005-10-11 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of a Mycobacterium tuberculosis NusA-RNA complex. Embo J., 24, 2005
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2XGU
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![BU of 2xgu by Molmil](/molmil-images/mine/2xgu) | Structure of the N-terminal domain of capsid protein from Rabbit Endogenous Lentivirus (RELIK) | Descriptor: | ACETATE ION, RELIK CAPSID N-TERMINAL DOMAIN | Authors: | Goldstone, D.C, Taylor, I.A, Robertson, L.E, Haire, L.F, Stoye, J.P. | Deposit date: | 2010-06-07 | Release date: | 2010-09-22 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.502 Å) | Cite: | Structural and Functional Analysis of Prehistoric Lentiviruses Uncovers an Ancient Molecular Interface. Cell Host Microbe, 8, 2010
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2XGY
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![BU of 2xgy by Molmil](/molmil-images/mine/2xgy) | Complex of Rabbit Endogenous Lentivirus (RELIK)Capsid with Cyclophilin A | Descriptor: | GLYCEROL, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A, RELIK CAPSID N-TERMINAL DOMAIN | Authors: | Goldstone, D.C, Robertson, L.E, Haire, L.F, Stoye, J.P, Taylor, I.A. | Deposit date: | 2010-06-08 | Release date: | 2010-09-22 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and Functional Analysis of Prehistoric Lentiviruses Uncovers an Ancient Molecular Interface. Cell Host Microbe, 8, 2010
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2XGV
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![BU of 2xgv by Molmil](/molmil-images/mine/2xgv) | Structure of the N-terminal domain of capsid protein from Rabbit Endogenous Lentivirus (RELIK) | Descriptor: | PSIV CAPSID N-TERMINAL DOMAIN | Authors: | Goldstone, D.C, Robertson, L.E, Haire, L.F, Stoye, J.P, Taylor, I.A. | Deposit date: | 2010-06-07 | Release date: | 2010-09-22 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and Functional Analysis of Prehistoric Lentiviruses Uncovers an Ancient Molecular Interface. Cell Host Microbe, 8, 2010
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4TN3
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![BU of 4tn3 by Molmil](/molmil-images/mine/4tn3) | Structure of the BBox-Coiled-coil region of Rhesus Trim5alpha | Descriptor: | TRIM5/cyclophilin A fusion protein/T4 Lysozyme chimera, ZINC ION | Authors: | Kirkpatrick, J.J, Stoye, J.P, Taylor, I.A, Goldstone, D.C. | Deposit date: | 2014-06-03 | Release date: | 2014-07-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.1989 Å) | Cite: | Structural studies of postentry restriction factors reveal antiparallel dimers that enable avid binding to the HIV-1 capsid lattice. Proc.Natl.Acad.Sci.USA, 111, 2014
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6QEY
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![BU of 6qey by Molmil](/molmil-images/mine/6qey) | IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties | Descriptor: | ACETONITRILE, Insulin-like growth factor 2 mRNA-binding protein 1, PHOSPHATE ION | Authors: | Dagil, R, Ball, N.J, Ogrodowicz, R.W, Purkiss, A.G, Taylor, I.A, Ramos, A. | Deposit date: | 2019-01-09 | Release date: | 2019-03-27 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties. Nucleic Acids Res., 47, 2019
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