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PDB: 164 results

4Y6M
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Structure of plasmepsin II from Plasmodium falciparum complexed with inhibitor PG418
Descriptor: GLYCEROL, Plasmepsin-2, ~{N}1-[(~{Z},3~{R})-4-[2-(3-methoxyphenyl)propan-2-ylamino]-3-oxidanyl-1-phenyl-but-1-en-2-yl]-5-piperidin-1-yl-~{N}3,~{N}3-dipropyl-benzene-1,3-dicarboxamide
Authors:Recacha, R, Akopjana, I, Tars, K, Jaudzems, K.
Deposit date:2015-02-13
Release date:2015-12-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structures of plasmepsin II from Plasmodium falciparum in complex with two hydroxyethylamine-based inhibitors.
Acta Crystallogr.,Sect.F, 71, 2015
2YN7
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Crystal structure of an outer surface protein BBA66 from Borrelia burgdorferi
Descriptor: OUTER SURFACE PROTEIN
Authors:Brangulis, K, Petrovskis, I, Kazaks, A, Ranka, R, Baumanis, V, Tars, K.
Deposit date:2012-10-12
Release date:2013-10-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure of the Infectious Phenotype-Associated Outer Surface Protein Bba66 from the Lyme Disease Agent Borrelia Burgdorferi.
Ticks Tick Borne Dis., 5, 2014
7Q47
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Endolysin from bacteriophage Enc34, catalytic domain
Descriptor: CHLORIDE ION, Endolysin, SODIUM ION
Authors:Cernooka, E, Rumnieks, J, Kazaks, A, Tars, K.
Deposit date:2021-10-29
Release date:2021-11-17
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Diversity of the lysozyme fold: structure of the catalytic domain from an unusual endolysin encoded by phage Enc34.
Sci Rep, 12, 2022
5MNT
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Bacteriophage Qbeta maturation protein
Descriptor: A2 maturation protein
Authors:Rumnieks, J, Tars, K.
Deposit date:2016-12-13
Release date:2017-01-11
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Crystal Structure of the Maturation Protein from Bacteriophage Q beta.
J. Mol. Biol., 429, 2017
5MJN
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BU of 5mjn by Molmil
Three dimensional structure of human carbonic anhydrase II in complex with 5-[(4Chlorobenzyl)sulfanyl]thiophene-2-sulfonamide
Descriptor: 5-[(4-chlorophenyl)methylsulfanyl]thiophene-2-sulfonamide, Carbonic anhydrase 2, ZINC ION
Authors:Leitans, J, Tars, K.
Deposit date:2016-12-01
Release date:2017-12-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.17 Å)
Cite:5-Substituted-benzylsulfanyl-thiophene-2-sulfonamides with effective carbonic anhydrase inhibitory activity: Solution and crystallographic investigations.
Bioorg. Med. Chem., 25, 2017
5ODL
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Single-stranded DNA-binding protein from bacteriophage Enc34 in complex with ssDNA
Descriptor: GLYCEROL, SODIUM ION, oligo(T), ...
Authors:Cernooka, E, Rumnieks, J, Kazaks, A, Tars, K.
Deposit date:2017-07-05
Release date:2017-10-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Structural Basis for DNA Recognition of a Single-stranded DNA-binding Protein from Enterobacter Phage Enc34.
Sci Rep, 7, 2017
2IZM
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MS2-RNA HAIRPIN (C-10) COMPLEX
Descriptor: 5'-R(*AP*CP*AP*UP*GP*CP*GP*GP*AP*UP *CP*AP*CP*CP*CP*AP*UP*GP*U)-3', Capsid protein
Authors:Helgstrand, C, Grahn, E, Moss, T, Stonehouse, N.J, Tars, K, Stockley, P.G, Liljas, L.
Deposit date:2006-07-25
Release date:2007-07-03
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Investigating the Structural Basis of Purine Specificity in the Structures of MS2 Coat Protein RNA Translational Operator Complexes
Nucleic Acids Res., 30, 2002
5ODK
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Single-stranded DNA-binding protein from bacteriophage Enc34, C-terminal truncation
Descriptor: GLYCEROL, PHOSPHATE ION, single-stranded DNA-binding protein
Authors:Cernooka, E, Rumnieks, J, Kazaks, A, Tars, K.
Deposit date:2017-07-05
Release date:2017-10-25
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Structural Basis for DNA Recognition of a Single-stranded DNA-binding Protein from Enterobacter Phage Enc34.
Sci Rep, 7, 2017
5ODJ
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Single-stranded DNA-binding protein from bacteriophage Enc34
Descriptor: CHLORIDE ION, MAGNESIUM ION, Single-stranded DNA-binding protein
Authors:Cernooka, E, Rumnieks, J, Kazaks, A, Tars, K.
Deposit date:2017-07-05
Release date:2017-10-25
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Basis for DNA Recognition of a Single-stranded DNA-binding Protein from Enterobacter Phage Enc34.
Sci Rep, 7, 2017
4YA8
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structure of plasmepsin II from Plasmodium Falciparum complexed with inhibitor PG394
Descriptor: GLYCEROL, N'-[(2S,3S)-3-hydroxy-1-phenyl-4-{[2-(pyridin-2-yl)propan-2-yl]amino}butan-2-yl]-N,N-dipropyl-5-(pyridin-1(2H)-yl)benzene-1,3-dicarboxamide, Plasmepsin-2
Authors:Recacha, R, Leitans, J, Tars, K, Jaudzems, K.
Deposit date:2015-02-17
Release date:2015-12-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.301 Å)
Cite:Structures of plasmepsin II from Plasmodium falciparum in complex with two hydroxyethylamine-based inhibitors.
Acta Crystallogr.,Sect.F, 71, 2015
6QO1
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Crystal structure of Borrelia (Borreliella) burgdorferi outer surface protein BBA69
Descriptor: Putative surface protein
Authors:Brangulis, K, Akopjana, I, Petrovskis, I, Kazaks, A, Tars, K.
Deposit date:2019-02-12
Release date:2019-06-26
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of Borrelia burgdorferi outer surface protein BBA69 in comparison to the paralogous protein CspA.
Ticks Tick Borne Dis, 10, 2019
4Z22
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BU of 4z22 by Molmil
structure of plasmepsin II from Plasmodium Falciparum complexed with inhibitor DR718A
Descriptor: 2-amino-7-phenyl-3-{[(2R,5S)-5-phenyltetrahydrofuran-2-yl]methyl}quinazolin-4(3H)-one, Plasmepsin-2
Authors:Recacha, R, Leitans, J, Tars, K, Jaudzems, K.
Deposit date:2015-03-28
Release date:2016-01-13
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones As Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV.
J.Med.Chem., 59, 2016
7POM
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BU of 7pom by Molmil
Three dimensional structure of human carbonic anhydrase IX in complex with sulfonamide
Descriptor: Carbonic anhydrase 9, ZINC ION, methyl 2-chloranyl-4-cyclohexylsulfanyl-5-sulfamoyl-benzoate
Authors:Leitans, J, Tars, K.
Deposit date:2021-09-09
Release date:2022-01-12
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Methyl 2-Halo-4-Substituted-5-Sulfamoyl-Benzoates as High Affinity and Selective Inhibitors of Carbonic Anhydrase IX.
Int J Mol Sci, 23, 2021
7PP9
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BU of 7pp9 by Molmil
Three dimensional structure of human carbonic anhydrase XII in complex with sulfonamide
Descriptor: Carbonic anhydrase 12, ZINC ION, methyl 2-chloranyl-4-cyclohexylsulfanyl-5-sulfamoyl-benzoate
Authors:Leitans, J, Tars, K, Dvinskis, E.
Deposit date:2021-09-13
Release date:2022-09-21
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Methyl 2-Halo-4-Substituted-5-Sulfamoyl-Benzoates as High Affinity and Selective Inhibitors of Carbonic Anhydrase IX.
Int J Mol Sci, 23, 2021
6QUT
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BU of 6qut by Molmil
Three dimensional structure of human carbonic anhydrase IX in complex with benzenesulfonamide
Descriptor: 4-chloranyl-~{N}-(3-oxidanylpropyl)-2-phenylsulfanyl-5-sulfamoyl-benzamide, Carbonic anhydrase 9, ZINC ION
Authors:Leitans, J, Tars, K.
Deposit date:2019-02-28
Release date:2020-03-25
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Halogenated and di-substituted benzenesulfonamides as selective inhibitors of carbonic anhydrase isoforms.
Eur.J.Med.Chem., 185, 2020
6QN2
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BU of 6qn2 by Molmil
Three dimensional structure of human carbonic anhydrase IX in complex with benzenesulfonamide
Descriptor: Carbonic anhydrase 9, ZINC ION, methyl 4-[(4-chloranyl-2-cyclohexylsulfanyl-5-sulfamoyl-phenyl)carbonylamino]butanoate
Authors:Leitans, J, Tars, K.
Deposit date:2019-02-08
Release date:2020-02-26
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Halogenated and di-substituted benzenesulfonamides as selective inhibitors of carbonic anhydrase isoforms.
Eur.J.Med.Chem., 185, 2020
6QNG
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BU of 6qng by Molmil
Three dimensional structure of human carbonic anhydrase XII in complex with benzenesulfonamide
Descriptor: Carbonic anhydrase 12, ZINC ION, ~{N}-butyl-4-chloranyl-2-(cyclohexylamino)-5-sulfamoyl-benzamide
Authors:Dvinskis, E, Leitans, J, Tars, K.
Deposit date:2019-02-11
Release date:2020-03-04
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Three dimensional structure of human carbonic anhydrase XII in complex with benzenesulfonamide
To Be Published
6QN0
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BU of 6qn0 by Molmil
Three dimensional structure of human carbonic anhydrase XII in complex with benzenesulfonamide
Descriptor: Carbonic anhydrase 12, ZINC ION, ~{N}-butyl-4-chloranyl-2-(2-phenylethylsulfanyl)-5-sulfamoyl-benzamide
Authors:Dvinskis, E, Leitans, J, Tars, K.
Deposit date:2019-02-08
Release date:2020-02-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Halogenated and di-substituted benzenesulfonamides as selective inhibitors of carbonic anhydrase isoforms.
Eur.J.Med.Chem., 185, 2020
2IZW
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BU of 2izw by Molmil
Crystal structure of Ryegrass Mottle Virus
Descriptor: RYEGRASS MOTTLE VIRUS COAT PROTEIN
Authors:Plevka, P, Tars, K, Zeltins, A, Balke, I, Truve, E, Liljas, L.
Deposit date:2006-07-27
Release date:2007-10-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The Three-Dimensional Structure of Ryegrass Mottle Virus at 2.9 A Resolution.
Virology, 369, 2007
6QN5
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BU of 6qn5 by Molmil
Three dimensional structure of human carbonic anhydrase IX in complex with benzenesulfonamide
Descriptor: 4-chloranyl-~{N}-(3-oxidanylpropyl)-2-phenylsulfanyl-5-sulfamoyl-benzamide, Carbonic anhydrase 9, ZINC ION
Authors:Leitans, J, Tars, K.
Deposit date:2019-02-09
Release date:2020-02-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Halogenated and di-substituted benzenesulfonamides as selective inhibitors of carbonic anhydrase isoforms.
Eur.J.Med.Chem., 185, 2020
6QNL
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BU of 6qnl by Molmil
Three dimensional structure of human carbonic anhydrase XII in complex with benzenesulfonamide
Descriptor: Carbonic anhydrase 12, ZINC ION, methyl 4-[(4-chloranyl-2-cyclohexylsulfanyl-5-sulfamoyl-phenyl)carbonylamino]butanoate
Authors:Dvinskis, E, Leitans, J, Tars, K.
Deposit date:2019-02-11
Release date:2020-03-04
Last modified:2021-10-06
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Halogenated and di-substituted benzenesulfonamides as selective inhibitors of carbonic anhydrase isoforms.
Eur.J.Med.Chem., 185, 2020
6QN6
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BU of 6qn6 by Molmil
Three dimensional structure of human carbonic anhydrase IX in complex with benzenesulfonamide
Descriptor: Carbonic anhydrase 9, ZINC ION, ~{N}-butyl-4-chloranyl-2-(2-phenylethylsulfanyl)-5-sulfamoyl-benzamide
Authors:Leitans, J, Tars, K.
Deposit date:2019-02-09
Release date:2020-02-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Halogenated and di-substituted benzenesulfonamides as selective inhibitors of carbonic anhydrase isoforms.
Eur.J.Med.Chem., 185, 2020
5A2U
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Crystal structure of BBA68 or BbCRASP-1 from Borrelia burgdorferi strain B31
Descriptor: COMPLEMENT REGULATOR ACQUIRING PROTEIN 1
Authors:Brangulis, K, Bertulis, E, Petrovskis, I, Kazaks, A, Tars, K.
Deposit date:2015-05-25
Release date:2015-06-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal Structure of Bba68 or Bbcrasp-1 from Borrelia Burgdorferi Strain B31
To be Published
2IZN
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BU of 2izn by Molmil
MS2-RNA HAIRPIN (G-10) COMPLEX
Descriptor: 5'-R(*AP*CP*AP*UP*CP*GP*CP*GP*AP*UP *UP*AP*CP*GP*GP*AP*UP*GP*U)-3', MS2 COAT PROTEIN
Authors:Helgstrand, C, Grahn, E, Moss, T, Stonehouse, N.J, Tars, K, Stockley, P.G, Liljas, L.
Deposit date:2006-07-25
Release date:2006-07-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Investigating the Structural Basis of Purine Specificity in the Structures of MS2 Coat Protein RNA Translational Operator Complexes
Nucleic Acids Res., 30, 2002
5A0U
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BU of 5a0u by Molmil
Structure of CutC choline lyase choline bound form from Klebsiella pneumoniae.
Descriptor: CHOLINE ION, CHOLINE TRIMETHYLAMINE LYASE
Authors:Kalnins, G, Tars, K.
Deposit date:2015-04-23
Release date:2015-07-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure and Function of Cutc Choline Lyase from Human Microbiota Bacterium Klebsiella Pneumoniaee
J.Biol.Chem., 290, 2015

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