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PDB: 95 件

4B5F
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Substrate bound Neisseria AP endonuclease in absence of metal ions (crystal form 1)
分子名称: 5'-D(*CP*GP*AP*TP*CP*GP*GP*TP*AP*GP*CP)-3', 5'-D(*GP*CP*TP*AP*CP*3DRP*GP*AP*TP*CP*GP)-3', PUTATIVE EXODEOXYRIBONUCLEASE
著者Lu, D, Silhan, J, MacDonald, J.T, Carpenter, E.P, Jensen, K, Tang, C.M, Baldwin, G.S, Freemont, P.S.
登録日2012-08-03
公開日2012-10-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.005 Å)
主引用文献Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis.
Proc. Natl. Acad. Sci. U.S.A., 109, 2012
4B5I
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Product complex of Neisseria AP endonuclease in presence of metal ions
分子名称: 5'-D(*3DRP*CP*AP*TP*CP*GP)-3', 5'-D(*CP*GP*AP*TP*GP*GP*GP*TP*AP*GP*CP)-3', 5'-D(*GP*CP*TP*AP*CP)-3', ...
著者Lu, D, Silhan, J, MacDonald, J.T, Carpenter, E.P, Jensen, K, Tang, C.M, Baldwin, G.S, Freemont, P.S.
登録日2012-08-03
公開日2012-10-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.555 Å)
主引用文献Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis.
Proc. Natl. Acad. Sci. U.S.A., 109, 2012
4B5J
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BU of 4b5j by Molmil
Neisseria AP endonuclease bound to the substrate with an orphan Adenine base
分子名称: 5'-D(*CP*GP*AP*TP*GP*AP*GP*TP*AP*GP*CP)-3', 5'-D(*GP*CP*TP*AP*CP*(3DR)P*CP*AP*TP*CP*GP)-3', PUTATIVE EXODEOXYRIBONUCLEASE
著者Lu, D, Silhan, J, MacDonald, J.T, Carpenter, E.P, Jensen, K, Tang, C.M, Baldwin, G.S, Freemont, P.S.
登録日2012-08-03
公開日2012-10-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis.
Proc. Natl. Acad. Sci. U.S.A., 109, 2012
8XIZ
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BU of 8xiz by Molmil
Crystal structure of an epoxide hydrolase mutant A250IC/L344V from Aspergillus usamii E001 at 2.17 Angstroms resolution
分子名称: Microsomal epoxide hyddrolase
著者Hu, B.C, Lu, Z.Y, Tang, C.D, Hu, D.
登録日2023-12-20
公開日2024-02-07
実験手法X-RAY DIFFRACTION (2.175 Å)
主引用文献Directed evolution of an epoxide hydrolase and its structural mechanism for the enantioselectivity improvement toward chiral ortho-fluorostyrene oxide
To Be Published
6BRG
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BU of 6brg by Molmil
The SAM domain of mouse SAMHD1 is critical for its activation and regulation
分子名称: Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, MAGNESIUM ION
著者Buzovetsky, O, Tang, C, Knecht, K.M, Antonucci, J.M, Wu, L, Ji, X, Xiong, Y.
登録日2017-11-30
公開日2018-02-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献The SAM domain of mouse SAMHD1 is critical for its activation and regulation.
Nat Commun, 9, 2018
6BRK
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The SAM domain of mouse SAMHD1 is critical for its activation and regulation
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, MAGNESIUM ION
著者Buzovetsky, O, Tang, C, Knecht, K.M, Antonucci, J.M, Wu, L, Ji, X, Xiong, Y.
登録日2017-11-30
公開日2018-02-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献The SAM domain of mouse SAMHD1 is critical for its activation and regulation.
Nat Commun, 9, 2018
6BRH
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BU of 6brh by Molmil
The SAM domain of mouse SAMHD1 is critical for its activation and regulation
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, MAGNESIUM ION
著者Buzovetsky, O, Tang, C, Knecht, K.M, Antonucci, J.M, Wu, L, Ji, X, Xiong, Y.
登録日2017-11-30
公開日2018-02-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献The SAM domain of mouse SAMHD1 is critical for its activation and regulation.
Nat Commun, 9, 2018
5XK4
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BU of 5xk4 by Molmil
Retracted state of S65-phosphorylated ubiquitin
分子名称: Polyubiquitin-B
著者Dong, X, Gong, Z, Qin, L.Y, Ran, M.L, Zhang, C.L, Liu, K, Liu, Z, Zhang, W.P, Tang, C.
登録日2017-05-05
公開日2017-06-28
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Ubiquitin S65 phosphorylation engenders a pH-sensitive conformational switch
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5XK5
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BU of 5xk5 by Molmil
Relaxed state of S65-phosphorylated ubiquitin
分子名称: Polyubiquitin-B
著者Xu, D, Zhou, G, Qin, L.Y, Ran, M.L, Zhang, C.L, Liu, K, Liu, Z, Zhang, W.P, Tang, C.
登録日2017-05-05
公開日2017-06-28
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Ubiquitin S65 phosphorylation engenders a pH-sensitive conformational switch
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5XBO
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BU of 5xbo by Molmil
Lanthanoid tagging via an unnatural amino acid for protein structure characterization
分子名称: Polyubiquitin-B, TERBIUM(III) ION, UV excision repair protein RAD23 homolog A
著者Jiang, W, Gu, X, Dong, X, Tang, C.
登録日2017-03-21
公開日2017-05-31
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Lanthanoid tagging via an unnatural amino acid for protein structure characterization
J. Biomol. NMR, 67, 2017
5YMY
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BU of 5ymy by Molmil
The structure of the complex between Rpn13 and K48-diUb
分子名称: Proteasomal ubiquitin receptor ADRM1, Ubiquitin
著者Liu, Z, Dong, X, Gong, Z, Yi, H.W, Liu, K, Yang, J, Zhang, W.P, Tang, C.
登録日2017-10-22
公開日2019-03-13
最終更新日2019-04-24
実験手法SOLUTION NMR
主引用文献Structural basis for the recognition of K48-linked Ub chain by proteasomal receptor Rpn13.
Cell Discov, 5, 2019
5YZ9
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BU of 5yz9 by Molmil
zinc finger domain of METTL3-METTL14 N6-methyladenosine methyltransferase
分子名称: N6-adenosine-methyltransferase catalytic subunit, ZINC ION
著者Dong, X, Tang, C, Gong, Z, Yin, P, Huang, J.B.
登録日2017-12-13
公開日2018-03-28
最終更新日2024-05-01
実験手法SOLUTION NMR, SOLUTION SCATTERING
主引用文献Solution structure of the RNA recognition domain of METTL3-METTL14 N6-methyladenosine methyltransferase.
Protein Cell, 10, 2019
7F7X
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Protein complex between phosphorylated ubiquitin and Ubqln2 UBA
分子名称: Polyubiquitin-B, Ubiquilin-2
著者Qin, L.Y, Dong, X, Tang, C.
登録日2021-06-30
公開日2022-05-18
実験手法SOLUTION NMR
主引用文献Kinetic Constraints in the Specific Interaction between Phosphorylated Ubiquitin and Proteasomal Shuttle Factors.
Biomolecules, 11, 2021
7YG4
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BU of 7yg4 by Molmil
Structure of WTAP-VIRMA in the m6A writer complex
分子名称: Pre-mRNA-splicing regulator WTAP, Protein virilizer homolog
著者Yan, X.H, Guan, Z.Y, Tang, C, Yin, P.
登録日2022-07-11
公開日2022-11-23
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献AI-empowered integrative structural characterization of m 6 A methyltransferase complex.
Cell Res., 32, 2022
7YFJ
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BU of 7yfj by Molmil
Crystal structure of human WTAP
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Pre-mRNA-splicing regulator WTAP
著者Yan, X.H, Guan, Z.Y, Tang, C, Yin, P.
登録日2022-07-08
公開日2023-01-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献AI-empowered integrative structural characterization of m 6 A methyltransferase complex.
Cell Res., 32, 2022
6Y7C
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BU of 6y7c by Molmil
Early cytoplasmic yeast pre-40S particle (purified with Tsr1 as bait)
分子名称: 20S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
著者Shayan, R, Plassart, L, Plisson-Chastang, C.
登録日2020-02-28
公開日2020-03-18
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Good Vibrations: Structural Remodeling of Maturing Yeast Pre-40S Ribosomal Particles Followed by Cryo-Electron Microscopy.
Molecules, 25, 2020
6ZUO
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BU of 6zuo by Molmil
Human RIO1(kd)-StHA late pre-40S particle, structural state A (pre 18S rRNA cleavage)
分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ...
著者Plassart, L, Shayan, R, Plisson-Chastang, C.
登録日2020-07-23
公開日2021-05-12
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献The final step of 40S ribosomal subunit maturation is controlled by a dual key lock.
Elife, 10, 2021
6ZV6
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BU of 6zv6 by Molmil
Human RIO1(kd)-StHA late pre-40S particle, structural state B (post 18S rRNA cleavage)
分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Plassart, L, Shayan, R, Plisson-Chastang, C.
登録日2020-07-24
公開日2021-05-12
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献The final step of 40S ribosomal subunit maturation is controlled by a dual key lock.
Elife, 10, 2021
6RBE
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BU of 6rbe by Molmil
State 2 of yeast Tsr1-TAP Rps20-Deltaloop pre-40S particles
分子名称: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
著者Shayan, R, Mitterer, V, Ferreira-Cerca, S, Murat, G, Enne, T, Rinaldi, D, Weigl, S, Omanic, H, Gleizes, P.E, Kressler, D, Pertschy, B, Plisson-Chastang, C.
登録日2019-04-10
公開日2019-06-26
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Conformational proofreading of distant 40S ribosomal subunit maturation events by a long-range communication mechanism.
Nat Commun, 10, 2019
6RBD
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BU of 6rbd by Molmil
State 1 of yeast Tsr1-TAP Rps20-Deltaloop pre-40S particles
分子名称: 20S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
著者Shayan, R, Mitterer, V, Ferreira-Cerca, S, Murat, G, Enne, T, Rinaldi, D, Weigl, S, Omanic, H, Gleizes, P.E, Kressler, D, Pertschy, B, Plisson-Chastang, C.
登録日2019-04-10
公開日2019-06-26
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Conformational proofreading of distant 40S ribosomal subunit maturation events by a long-range communication mechanism.
Nat Commun, 10, 2019
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