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PDB: 601 件

5VKG
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Solution-state NMR structural ensemble of human Tsg101 UEV in complex with tenatoprazole
分子名称: 4-methoxy-1-(5-methoxy-3H-imidazo[4,5-b]pyridin-2-yl)-3,5-dimethyl-2-(sulfanylmethyl)pyridin-1-ium, Tumor susceptibility gene 101 protein
著者Strickland, M, Ehrlich, L.S, Watanabe, S, Khan, M, Strub, M.-P, Luan, C.H, Powell, M.D, Leis, J, Tjandra, N, Carter, C.
登録日2017-04-21
公開日2017-11-15
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Tsg101 chaperone function revealed by HIV-1 assembly inhibitors.
Nat Commun, 8, 2017
8BYJ
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The structures of Ace2 in complex with bicyclic peptide inhibitor
分子名称: 1-[3,5-bis(3-bromanylpropanoyl)-1,3,5-triazinan-1-yl]-3-bromanyl-propan-1-one, ALA-CYS-VAL-ARG-SER-HIS-CYS-SER-SER-LEU-LEU-PRO-ARG-ILE-HIS-CYS-ALA, Processed angiotensin-converting enzyme 2, ...
著者Brear, P, Lulla, A, Harman, M, Dods, R, Chen, L, Bezerra, G, Demydchuk, Y, Stanway, S, Hyvonen, M.
登録日2022-12-13
公開日2023-09-20
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Structure-Guided Chemical Optimization of Bicyclic Peptide ( Bicycle ) Inhibitors of Angiotensin-Converting Enzyme 2.
J.Med.Chem., 66, 2023
7SSA
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Cryo-EM structure of pioneer factor Cbf1 bound to the nucleosome
分子名称: Centromere-binding protein 1, DNA (137-MER), Histone H2A.1, ...
著者Eek, P, Tan, S.
登録日2021-11-10
公開日2023-04-05
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Basic helix-loop-helix pioneer factors interact with the histone octamer to invade nucleosomes and generate nucleosome-depleted regions.
Mol.Cell, 83, 2023
8IBN
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BU of 8ibn by Molmil
Cryo-EM structure of KpFtsZ single filament
分子名称: Cell division protein FtsZ, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, POTASSIUM ION
著者Fujita, J, Amesaka, H, Yoshizawa, T, Kuroda, N, Kamimura, N, Hibino, K, Konishi, T, Kato, Y, Hara, M, Inoue, T, Namba, K, Tanaka, S, Matsumura, H.
登録日2023-02-10
公開日2023-08-02
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Structures of a FtsZ single protofilament and a double-helical tube in complex with a monobody.
Nat Commun, 14, 2023
2GBL
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BU of 2gbl by Molmil
Crystal Structure of Full Length Circadian Clock Protein KaiC with Phosphorylation Sites
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase kaiC, MAGNESIUM ION
著者Pattanayek, R, Williams, D.R, Pattanayek, S, Xu, Y, Mori, T, Johnson, C.H, Stewart, P.L, Egli, M.
登録日2006-03-10
公開日2007-01-23
最終更新日2021-07-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Analysis of KaiA-KaiC protein interactions in the cyano-bacterial circadian clock using hybrid structural methods.
Embo J., 25, 2006
1NH2
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BU of 1nh2 by Molmil
Crystal structure of a yeast TFIIA/TBP/DNA complex
分子名称: 5'-D(*GP*TP*TP*TP*TP*AP*TP*AP*TP*AP*CP*AP*TP*AP*CP*A)-3', 5'-D(*TP*GP*TP*AP*(5IU)P*GP*TP*AP*TP*AP*(5IU)P*AP*AP*AP*AP*C)-3', Transcription initiation factor IIA large chain, ...
著者Bleichenbacher, M, Tan, S, Richmond, T.J.
登録日2002-12-18
公開日2003-10-21
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Novel interactions between the components of human and yeast TFIIA/TBP/DNA complexes.
J.Mol.Biol., 332, 2003
1NVP
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HUMAN TFIIA/TBP/DNA COMPLEX
分子名称: 5'-D(*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*CP*CP*CP*CP*CP*C)-3', 5'-D(*GP*GP*GP*GP*GP*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*G)-3', TATA box binding protein, ...
著者Bleichenbacher, M, Tan, S, Richmond, T.J.
登録日2003-02-04
公開日2003-10-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Novel interactions between the components of human and yeast TFIIA/TBP/DNA complexes.
J.Mol.Biol., 332, 2003
2XHB
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Crystal structure of DNA polymerase from Thermococcus gorgonarius in complex with hypoxanthine-containing DNA
分子名称: 5'-D(*AP*AP*AP*AP*AP*AP*AP*AP*A)-3', DNA POLYMERASE, HYPOXANTHINE-CONTAINING DNA, ...
著者Killelea, T, Ghosh, S, Tan, S.S, Heslop, P, Firbank, S.J, Kool, E.T, Connolly, B.A.
登録日2010-06-14
公開日2010-07-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Probing the Interaction of Archaeal DNA Polymerases with Deaminated Bases Using X-Ray Crystallography and Non-Hydrogen Bonding Isosteric Base Analogues.
Biochemistry, 49, 2010
7DO7
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BU of 7do7 by Molmil
Crystal structure of Azotobacter vinelandii L-rhamnose 1-dehydrogenase(NAD and L-rhamnose bound-form)
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Short-chain dehydrogenase/reductase SDR, beta-L-rhamnopyranose
著者Yoshiwara, K, Watanabe, Y, Watanabe, S.
登録日2020-12-12
公開日2021-02-03
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Crystal structure of l-rhamnose 1-dehydrogenase involved in the nonphosphorylative pathway of l-rhamnose metabolism in bacteria.
Febs Lett., 595, 2021
7D2R
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BU of 7d2r by Molmil
Crystal structure of Agrobacterium tumefaciens aconitase X mutant - S449C/C510V
分子名称: FE2/S2 (INORGANIC) CLUSTER, GLYCEROL, SODIUM ION, ...
著者Murase, Y, Watanabe, Y, Watanabe, S.
登録日2020-09-17
公開日2021-06-16
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.005 Å)
主引用文献Crystal structures of aconitase X enzymes from bacteria and archaea provide insights into the molecular evolution of the aconitase superfamily.
Commun Biol, 4, 2021
2ROZ
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BU of 2roz by Molmil
Structure of the C-terminal PID Domain of Fe65L1 Complexed with the Cytoplasmic Tail of APP Reveals a Novel Peptide Binding Mode
分子名称: Amyloid beta A4 precursor protein-binding family B member 2, peptide from Amyloid beta A4 protein
著者Li, H, Koshiba, S, Tochio, N, Watanabe, S, Harada, T, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2008-04-25
公開日2008-07-22
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of the C-terminal phosphotyrosine interaction domain of Fe65L1 complexed with the cytoplasmic tail of amyloid precursor protein reveals a novel peptide binding mode
J.Biol.Chem., 283, 2008
8G57
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Structure of nucleosome-bound Sirtuin 6 deacetylase
分子名称: DNA strand 1, DNA strand 2, Histone H2A type 1-B/E, ...
著者Chio, U.S, Rechiche, O, Bryll, A.R, Zhu, J, Feldman, J.L, Peterson, C.L, Tan, S, Armache, J.-P.
登録日2023-02-11
公開日2023-04-26
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Cryo-EM structure of the human Sirtuin 6-nucleosome complex.
Sci Adv, 9, 2023
4GCB
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BU of 4gcb by Molmil
100K X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL
分子名称: CHLORIDE ION, Cisplatin, DIMETHYL SULFOXIDE, ...
著者Helliwell, J.R, Tanley, S.W.M.
登録日2012-07-30
公開日2013-01-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The crystal structure analysis of the relative binding of cisplatin and carboplatin in a mixture with histidine in a protein studied at 100 and 300 K with repeated X-ray irradiation.
Acta Crystallogr.,Sect.D, 69, 2013
4GCF
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BU of 4gcf by Molmil
Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL, Dataset 4
分子名称: DIMETHYL SULFOXIDE, Lysozyme C, PLATINUM (II) ION
著者Helliwell, J.R, Tanley, S.W.M.
登録日2012-07-30
公開日2013-01-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献The crystal structure analysis of the relative binding of cisplatin and carboplatin in a mixture with histidine in a protein studied at 100 and 300 K with repeated X-ray irradiation.
Acta Crystallogr.,Sect.D, 69, 2013
4GCC
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BU of 4gcc by Molmil
Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL, Dataset 1
分子名称: Cisplatin, DIMETHYL SULFOXIDE, Lysozyme C
著者Helliwell, J.R, Tanley, S.W.M.
登録日2012-07-30
公開日2013-01-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structure analysis of the relative binding of cisplatin and carboplatin in a mixture with histidine in a protein studied at 100 and 300 K with repeated X-ray irradiation.
Acta Crystallogr.,Sect.D, 69, 2013
3VHQ
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BU of 3vhq by Molmil
Crystal structure of the Ca6 site mutant of Pro-SA-subtilisin
分子名称: CALCIUM ION, Tk-subtilisin
著者Uehara, R, Takeuchi, Y, Tanaka, S, Matsumura, H, Koga, Y, Takano, K, Kanaya, S.
登録日2011-09-01
公開日2012-07-11
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Requirement of Ca(2+) Ions for the Hyperthermostability of Tk-Subtilisin from Thermococcus kodakarensis
Biochemistry, 51, 2012
4GCD
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BU of 4gcd by Molmil
Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL, Dataset 2
分子名称: Cisplatin, DIMETHYL SULFOXIDE, Lysozyme C
著者Helliwell, J.R, Tanley, S.W.M.
登録日2012-07-30
公開日2013-01-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The crystal structure analysis of the relative binding of cisplatin and carboplatin in a mixture with histidine in a protein studied at 100 and 300 K with repeated X-ray irradiation.
Acta Crystallogr.,Sect.D, 69, 2013
2RNL
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BU of 2rnl by Molmil
Solution structure of the EGF-like domain from human Amphiregulin
分子名称: Amphiregulin
著者Qin, X, Hayashi, F, Terada, T, Shirouzu, M, Watanabe, S, Kigawa, T, Yabuta, N, Nojima, H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2008-01-11
公開日2009-01-20
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Solution structure of the EGF-like domain from human Amphiregulin
To be Published
5GRJ
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Crystal structure of human PD-L1 with monoclonal antibody avelumab
分子名称: Programmed cell death 1 ligand 1, avelumab H chain, avelumab L chain
著者Liu, K, Tan, S, Chai, Y, Chen, D, Song, H, Zhang, C.W.-H, Shi, Y, Liu, J, Tan, W, Lyu, J, Gao, S, Yan, J, Qi, J, Gao, G.F.
登録日2016-08-11
公開日2016-11-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.206 Å)
主引用文献Structural basis of anti-PD-L1 monoclonal antibody avelumab for tumor therapy.
Cell Res., 27, 2017
8I5D
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BU of 8i5d by Molmil
Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK)
分子名称: Beta-2-microglobulin, MHC class I antigen (Fragment), TCR alpha chain, ...
著者Lu, D, Chen, Y, Jiang, M, Tan, S.G, Chai, Y, Gao, G.F.
登録日2023-01-25
公開日2023-08-23
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK)
Nat Commun, 2023
6KYI
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Rice Rubisco in complex with sulfate ions
分子名称: GLYCEROL, Ribulose bisphosphate carboxylase large chain, Ribulose bisphosphate carboxylase small chain, ...
著者Matsumura, H, Yoshizawa, T, Tanaka, S, Yoshikawa, H.
登録日2019-09-19
公開日2020-09-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Hybrid Rubisco with Complete Replacement of Rice Rubisco Small Subunits by Sorghum Counterparts Confers C 4 Plant-like High Catalytic Activity.
Mol Plant, 13, 2020
3VND
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BU of 3vnd by Molmil
Crystal structure of tryptophan synthase alpha-subunit from the psychrophile Shewanella frigidimarina K14-2
分子名称: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, SULFATE ION, Tryptophan synthase alpha chain
著者Mitsuya, D, Tanaka, S, Matsumura, H, Takano, K, Urano, N, Ishida, M.
登録日2012-01-12
公開日2013-01-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Strategy for cold adaptation of the tryptophan synthase alpha subunit from the psychrophile Shewanella frigidimarina K14-2: crystal structure and physicochemical properties
J.Biochem., 155, 2014
4G9I
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Crystal structure of T.kodakarensis HypF
分子名称: Hydrogenase maturation protein HypF, ZINC ION
著者Tominaga, T, Watanabe, S, Matsumi, R, Atomi, H, Imanaka, T, Miki, K.
登録日2012-07-24
公開日2012-10-24
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Structure of the [NiFe]-hydrogenase maturation protein HypF from Thermococcus kodakarensis KOD1.
Acta Crystallogr.,Sect.F, 68, 2012
6M4E
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BU of 6m4e by Molmil
Crystal structure of a GH1 beta-glucosidase from Hamamotoa singularis
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Uehara, R, Iwamoto, R, Aoki, S, Yoshizawa, T, Takano, K, Matsumura, H, Tanaka, S.-i.
登録日2020-03-06
公開日2020-09-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of a GH1 beta-glucosidase from Hamamotoa singularis.
Protein Sci., 29, 2020
6M55
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Crystal structure of the E496A mutant of HsBglA in complex with 4-galactosyllactose
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-galactosidase-like enzyme, ...
著者Uehara, R, Iwamoto, R, Aoki, S, Yoshizawa, T, Takano, K, Matsumura, H, Tanaka, S.-i.
登録日2020-03-10
公開日2020-09-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of a GH1 beta-glucosidase from Hamamotoa singularis.
Protein Sci., 29, 2020

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