6UUY
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2H0R
| Structure of the Yeast Nicotinamidase Pnc1p | Descriptor: | Nicotinamidase, ZINC ION | Authors: | Taylor, A.B, Hu, G, Hart, P.J, McAlister-Henn, L. | Deposit date: | 2006-05-15 | Release date: | 2007-03-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of the yeast nicotinamidase Pnc1p. Arch.Biochem.Biophys., 461, 2007
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3RBZ
| MthK channel, Ca2+-bound | Descriptor: | CALCIUM ION, Calcium-gated potassium channel mthK | Authors: | Taylor, A.B, Parfenova, L.V, Rothberg, B.S. | Deposit date: | 2011-03-30 | Release date: | 2011-10-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structures of multiple Ca2+-binding sites in a K+ channel RCK domain Proc.Natl.Acad.Sci.USA, 2011
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4OTA
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4OTC
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1ZPU
| Crystal Structure of Fet3p, a Multicopper Oxidase that Functions in Iron Import | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (I) ION, ... | Authors: | Taylor, A.B, Stoj, C.S, Ziegler, L, Kosman, D.J, Hart, P.J. | Deposit date: | 2005-05-17 | Release date: | 2005-10-04 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The copper-iron connection in biology: Structure of the metallo-oxidase Fet3p. Proc.Natl.Acad.Sci.Usa, 102, 2005
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4GDP
| Yeast polyamine oxidase FMS1, N195A mutant | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Polyamine oxidase FMS1, TETRAETHYLENE GLYCOL | Authors: | Taylor, A.B, Adachi, M.S, Hart, P.J, Fitzpatrick, P.F. | Deposit date: | 2012-08-01 | Release date: | 2012-10-17 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9998 Å) | Cite: | Mechanistic and Structural Analyses of the Roles of Active Site Residues in Yeast Polyamine Oxidase Fms1: Characterization of the N195A and D94N Enzymes. Biochemistry, 51, 2012
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1HR6
| Yeast Mitochondrial Processing Peptidase | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MITOCHONDRIAL PROCESSING PEPTIDASE ALPHA SUBUNIT, MITOCHONDRIAL PROCESSING PEPTIDASE BETA SUBUNIT, ... | Authors: | Taylor, A.B, Smith, B.S, Kitada, S, Kojima, K, Miyaura, H, Otwinowski, Z, Ito, A, Deisenhofer, J. | Deposit date: | 2000-12-21 | Release date: | 2001-07-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of mitochondrial processing peptidase reveal the mode for specific cleavage of import signal sequences. Structure, 9, 2001
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1HR8
| Yeast Mitochondrial Processing Peptidase beta-E73Q Mutant Complexed with Cytochrome C Oxidase IV Signal Peptide | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CYTOCHROME C OXIDASE POLYPEPTIDE IV, MITOCHONDRIAL PROCESSING PEPTIDASE ALPHA SUBUNIT, ... | Authors: | Taylor, A.B, Smith, B.S, Kitada, S, Kojima, K, Miyaura, H, Otwinowski, Z, Ito, A, Deisenhofer, J. | Deposit date: | 2000-12-21 | Release date: | 2001-07-11 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structures of mitochondrial processing peptidase reveal the mode for specific cleavage of import signal sequences. Structure, 9, 2001
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4OTB
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1HR9
| Yeast Mitochondrial Processing Peptidase beta-E73Q Mutant Complexed with Malate Dehydrogenase Signal Peptide | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MALATE DEHYDROGENASE, MITOCHONDRIAL PROCESSING PEPTIDASE ALPHA SUBUNIT, ... | Authors: | Taylor, A.B, Smith, B.S, Kitada, S, Kojima, K, Miyaura, H, Otwinowski, Z, Ito, A, Deisenhofer, J. | Deposit date: | 2000-12-21 | Release date: | 2001-07-11 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Crystal structures of mitochondrial processing peptidase reveal the mode for specific cleavage of import signal sequences. Structure, 9, 2001
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1HR7
| Yeast Mitochondrial Processing Peptidase beta-E73Q Mutant | Descriptor: | MITOCHONDRIAL PROCESSING PEPTIDASE ALPHA SUBUNIT, MITOCHONDRIAL PROCESSING PEPTIDASE BETA SUBUNIT, ZINC ION | Authors: | Taylor, A.B, Smith, B.S, Kitada, S, Kojima, K, Miyaura, H, Otwinowski, Z, Ito, A, Deisenhofer, J. | Deposit date: | 2000-12-21 | Release date: | 2001-07-11 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Crystal structures of mitochondrial processing peptidase reveal the mode for specific cleavage of import signal sequences. Structure, 9, 2001
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5U9M
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5TX2
| Miniature TGF-beta2 3-mutant monomer | Descriptor: | Transforming growth factor beta-2 | Authors: | Taylor, A.B, Kim, S.K, Hart, P.J, Hinck, A.P. | Deposit date: | 2016-11-15 | Release date: | 2017-03-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | An engineered transforming growth factor beta (TGF-beta ) monomer that functions as a dominant negative to block TGF-beta signaling. J. Biol. Chem., 292, 2017
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5UWK
| Matrix metalloproteinase-13 complexed with selective inhibitor compound (S)-10a | Descriptor: | (S)-3-methyl-2-(4'-(((4-oxo-4,5,6,7-tetrahydro-3H-cyclopenta[d]pyrimidin-2-yl)thio)methyl)-[1,1'-biphenyl]-4-ylsulfonamido)butanoic acid, CALCIUM ION, Collagenase 3, ... | Authors: | Taylor, A.B, Cao, X, Hart, P.J. | Deposit date: | 2017-02-21 | Release date: | 2017-07-12 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure-Based Design and Synthesis of Potent and Selective Matrix Metalloproteinase 13 Inhibitors. J. Med. Chem., 60, 2017
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5TIW
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5T0R
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5T0S
| Synaptotagmin 1 C2B domain, cadmium-bound | Descriptor: | CADMIUM ION, SODIUM ION, Synaptotagmin-1 | Authors: | Taylor, A.B, Hart, P.J, Igumenova, T.I. | Deposit date: | 2016-08-16 | Release date: | 2017-06-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Non-Native Metal Ion Reveals the Role of Electrostatics in Synaptotagmin 1-Membrane Interactions. Biochemistry, 56, 2017
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4ECH
| Yeast Polyamine Oxidase FMS1, H67Q Mutant | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Polyamine oxidase FMS1 | Authors: | Taylor, A.B, Adachi, M.S, Hart, P.J, Fitzpatrick, P.F. | Deposit date: | 2012-03-26 | Release date: | 2012-06-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Mechanistic and structural analyses of the role of his67 in the yeast polyamine oxidase fms1. Biochemistry, 51, 2012
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5TIX
| Schistosoma haematobium (Blood Fluke) Sulfotransferase/R-oxamniquine Complex | Descriptor: | ADENOSINE-3'-5'-DIPHOSPHATE, Sulfotransferase, {(2R)-7-nitro-2-[(propan-2-ylamino)methyl]-1,2,3,4-tetrahydroquinolin-6-yl}methanol | Authors: | Taylor, A.B, Hart, P.J. | Deposit date: | 2016-10-03 | Release date: | 2017-05-31 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structural and enzymatic insights into species-specific resistance to schistosome parasite drug therapy. J. Biol. Chem., 292, 2017
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5TIV
| Schistosoma haematobium (Blood Fluke) Sulfotransferase | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-3'-5'-DIPHOSPHATE, Sulfotransferase | Authors: | Taylor, A.B, Hart, P.J. | Deposit date: | 2016-10-03 | Release date: | 2017-05-31 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Structural and enzymatic insights into species-specific resistance to schistosome parasite drug therapy. J. Biol. Chem., 292, 2017
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5TIY
| Schistosoma haematobium (Blood Fluke) Sulfotransferase/S-oxamniquine Complex | Descriptor: | ADENOSINE-3'-5'-DIPHOSPHATE, Sulfotransferase, {(2S)-7-nitro-2-[(propan-2-ylamino)methyl]-1,2,3,4-tetrahydroquinolin-6-yl}methanol | Authors: | Taylor, A.B, Hart, P.J. | Deposit date: | 2016-10-03 | Release date: | 2017-05-31 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Structural and enzymatic insights into species-specific resistance to schistosome parasite drug therapy. J. Biol. Chem., 292, 2017
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5TIZ
| Schistosoma japonicum (Blood Fluke) Sulfotransferase | Descriptor: | ADENOSINE-3'-5'-DIPHOSPHATE, Sulfotransferase | Authors: | Taylor, A.B, Hart, P.J. | Deposit date: | 2016-10-03 | Release date: | 2017-05-31 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.87 Å) | Cite: | Structural and enzymatic insights into species-specific resistance to schistosome parasite drug therapy. J. Biol. Chem., 292, 2017
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8E5R
| Schistosoma mansoni (Blood Fluke) Sulfotransferase/CIDD-0150610 Complex | Descriptor: | ADENOSINE-3'-5'-DIPHOSPHATE, Sulfotransferase oxamniquine resistance protein, [4-({[(3R)-1-[(1H-indol-3-yl)methyl]-3-{[4-(trifluoromethyl)phenyl]methyl}pyrrolidin-3-yl]methyl}amino)-3-nitrophenyl]methanol | Authors: | Taylor, A.B, Alwan, S.N. | Deposit date: | 2022-08-22 | Release date: | 2023-07-26 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Oxamniquine derivatives overcome Praziquantel treatment limitations for Schistosomiasis. Plos Pathog., 19, 2023
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8E5Q
| Schistosoma mansoni (Blood Fluke) Sulfotransferase/CIDD-0150303 Complex | Descriptor: | ADENOSINE-3'-5'-DIPHOSPHATE, Sulfotransferase oxamniquine resistance protein, [2-(dihydroxyamino)-4-({[(3R)-1-[(1H-indol-3-yl)methyl]-3-{[3-(trifluoromethyl)phenyl]methyl}pyrrolidin-3-yl]methyl}amino)phenyl]methanol | Authors: | Taylor, A.B, Alwan, S.N. | Deposit date: | 2022-08-22 | Release date: | 2023-07-26 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Oxamniquine derivatives overcome Praziquantel treatment limitations for Schistosomiasis. Plos Pathog., 19, 2023
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