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PDB: 1352 results

1GRW
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C. elegans major sperm protein
Descriptor: MAJOR SPERM PROTEIN 31/40/142
Authors:Baker, A.M.E, Roberts, T.M, Stewart, M.
Deposit date:2001-12-18
Release date:2002-06-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:2.6 A Resolution Crystal Structure of Helices of the Motile Major Sperm Protein (Msp) of Caenorhabditis Elegans
J.Mol.Biol., 319, 2002
8PCW
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Structure of Csm6' from Streptococcus thermophilus
Descriptor: CRISPR system endoribonuclease Csm6'
Authors:McQuarrie, S.J, Athukoralage, J.S, McMahon, S.A, Graham, S, Ackerman, K, Bode, B.E, White, M.F, Gloster, T.M.
Deposit date:2023-06-11
Release date:2023-10-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.54 Å)
Cite:Activation of Csm6 ribonuclease by cyclic nucleotide binding: in an emergency, twist to open.
Nucleic Acids Res., 51, 2023
8PE3
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Structure of Csm6' from Streptococcus thermophilus in complex with cyclic hexa-adenylate (cA6)
Descriptor: CRISPR system endoribonuclease Csm6', Cyclic hexaadenosine monophosphate (cA6), RNA
Authors:McQuarrie, S.J, Athukoralage, J.S, McMahon, S.A, Graham, S, Ackerman, K, Bode, B.E, White, M.F, Gloster, T.M.
Deposit date:2023-06-13
Release date:2023-10-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Activation of Csm6 ribonuclease by cyclic nucleotide binding: in an emergency, twist to open.
Nucleic Acids Res., 51, 2023
8PC2
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SelDeg51 in complex with FKBP51FK1 domain and pVHL:EloB:EloC
Descriptor: Elongin-B, Elongin-C, Peptidyl-prolyl cis-trans isomerase FKBP5, ...
Authors:Meyners, C, Walz, M, Geiger, T.M, Hausch, F.
Deposit date:2023-06-09
Release date:2023-11-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Discovery of a Potent Proteolysis Targeting Chimera Enables Targeting the Scaffolding Functions of FK506-Binding Protein 51 (FKBP51).
Angew.Chem.Int.Ed.Engl., 63, 2024
8PDF
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FKBP12 in complex with PROTAC 6a2
Descriptor: (2~{S},4~{R})-1-[(2~{S})-2-[2-[2-[2-[4-[(1~{S})-1-[(1~{S},5~{S},6~{R})-10-[3,5-bis(chloranyl)phenyl]sulfonyl-5-ethenyl-2-oxidanylidene-3,10-diazabicyclo[4.3.1]decan-3-yl]ethyl]-1,2,3-triazol-1-yl]ethoxy]ethoxy]ethanoylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Peptidyl-prolyl cis-trans isomerase FKBP1A
Authors:Meyners, C, Walz, M, Geiger, T.M, Hausch, F.
Deposit date:2023-06-12
Release date:2023-11-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Discovery of a Potent Proteolysis Targeting Chimera Enables Targeting the Scaffolding Functions of FK506-Binding Protein 51 (FKBP51).
Angew.Chem.Int.Ed.Engl., 63, 2024
3O5B
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Crystal structure of dimeric KlHxk1 in crystal form VII with glucose bound (open state)
Descriptor: Hexokinase, SULFATE ION, beta-D-glucopyranose
Authors:Kuettner, E.B, Kettner, K, Keim, A, Kriegel, T.M, Strater, N.
Deposit date:2010-07-28
Release date:2010-10-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Crystal Structure of Hexokinase KlHxk1 of Kluyveromyces lactis: A MOLECULAR BASIS FOR UNDERSTANDING THE CONTROL OF YEAST HEXOKINASE FUNCTIONS VIA COVALENT MODIFICATION AND OLIGOMERIZATION.
J.Biol.Chem., 285, 2010
2JKA
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Native structure of a family 97 alpha-glucosidase from Bacteroides thetaiotaomicron
Descriptor: 1,2-ETHANEDIOL, ALPHA-GLUCOSIDASE (ALPHA-GLUCOSIDASE SUSB), CALCIUM ION
Authors:Gloster, T.M, Turkenburg, J.P, Potts, J.R, Henrissat, B, Davies, G.J.
Deposit date:2008-08-23
Release date:2008-09-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Divergence of Catalytic Mechanism within a Glycosidase Family Provides Insight Into Evolution of Carbohydrate Metabolism by Human Gut Flora.
Chem.Biol., 15, 2008
7BDV
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BU of 7bdv by Molmil
Structure of Can2 from Sulfobacillus thermosulfidooxidans in complex with cyclic tetra-adenylate (cA4)
Descriptor: Can2, Cyclic tetraadenosine monophosphate (cA4)
Authors:McQuarrie, S, McMahon, S.A, Gloster, T.M, White, M.F, Graham, S, Zhu, W, Gruschow, S.
Deposit date:2020-12-22
Release date:2021-03-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:The CRISPR ancillary effector Can2 is a dual-specificity nuclease potentiating type III CRISPR defence.
Nucleic Acids Res., 49, 2021
4DBS
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BU of 4dbs by Molmil
Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 (AKR1C3) in complex with NADP+ and 3'-[(4-nitronaphthalen-1-yl)amino]benzoic acid
Descriptor: 3-[(4-nitronaphthalen-1-yl)amino]benzoic acid, Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Chen, M, Christianson, D.W, Winkler, J.D, Penning, T.M.
Deposit date:2012-01-16
Release date:2012-03-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.852 Å)
Cite:Crystal structures of AKR1C3 containing an N-(aryl)amino-benzoate inhibitor and a bifunctional AKR1C3 inhibitor and androgen receptor antagonist. Therapeutic leads for castrate resistant prostate cancer.
Bioorg.Med.Chem.Lett., 22, 2012
3O26
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The structure of salutaridine reductase from Papaver somniferum.
Descriptor: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Salutaridine reductase
Authors:Higashi, Y, Kutchen, T.M, Smith, T.J.
Deposit date:2010-07-22
Release date:2010-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:The atomic structure of salutaridine reductase from the opium poppy Papaver somniferum.
J.Biol.Chem., 66, 2010
4DMX
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Cathepsin K inhibitor
Descriptor: (1R,2R)-N-(1-cyanocyclopropyl)-2-{[4-(4-fluorophenyl)piperazin-1-yl]carbonyl}cyclohexanecarboxamide, Cathepsin K, GLYCEROL
Authors:Dossetter, A.G, Beeley, H, Bowyer, J, Cook, C.R, Crawford, J.J, Finlayson, J.E, Heron, N.M, Heyes, C, Highton, A.J, Hudson, J.A, Kenny, P.W, Martin, S, MacFaul, P.A, McGuire, T.M, Gutierrez, P.M, Morley, A.D, Morris, J.J, Page, K.M, Rosenbrier Ribeiro, L, Sawney, H, Steinbacher, S, Krapp, S, Jestel, A, Smith, C, Vickers, M.
Deposit date:2012-02-08
Release date:2012-07-11
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:(1R,2R)-N-(1-cyanocyclopropyl)-2-(6-methoxy-1,3,4,5-tetrahydropyrido[4,3-b]indole-2-carbonyl)cyclohexanecarboxamide (AZD4996): a potent and highly selective cathepsin K inhibitor for the treatment of osteoarthritis.
J.Med.Chem., 55, 2012
4DMY
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Cathepsin K inhibitor
Descriptor: (1R,2R)-N-(1-cyanocyclopropyl)-2-[(8-fluoro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)carbonyl]cyclohexanecarboxamide, Cathepsin K, GLYCEROL, ...
Authors:Dossetter, A.G, Beeley, H, Bowyer, J, Cook, C.R, Crawford, J.J, Finlayson, J.E, Heron, N.M, Heyes, C, Highton, A.J, Hudson, J.A, Kenny, P.W, Martin, S, MacFaul, P.A, McGuire, T.M, Gutierrez, P.M, Morley, A.D, Morris, J.J, Page, K.M, Rosenbrier Ribeiro, L, Sawney, H, Steinbacher, S, Krapp, S, Jestel, A, Smith, C, Vickers, M.
Deposit date:2012-02-08
Release date:2012-07-11
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:(1R,2R)-N-(1-cyanocyclopropyl)-2-(6-methoxy-1,3,4,5-tetrahydropyrido[4,3-b]indole-2-carbonyl)cyclohexanecarboxamide (AZD4996): a potent and highly selective cathepsin K inhibitor for the treatment of osteoarthritis.
J.Med.Chem., 55, 2012
4DBW
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Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 (AKR1C3) in complex with NADP+ and 2'-desmethyl-indomethacin
Descriptor: Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, [1-(4-chlorobenzoyl)-5-methoxy-1H-indol-3-yl]acetic acid
Authors:Chen, M, Christianson, D.W, Marnett, L.J, Penning, T.M.
Deposit date:2012-01-16
Release date:2013-03-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Development of potent and selective indomethacin analogues for the inhibition of AKR1C3 (Type 5 17 beta-hydroxysteroid dehydrogenase/prostaglandin F synthase) in castrate-resistant prostate cancer.
J.Med.Chem., 56, 2013
2KHY
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Specifier Domain of B. subtilis tyrS T box leader RNA
Descriptor: RNA (38-MER)
Authors:Wang, J, Henkin, T.M.
Deposit date:2009-04-14
Release date:2010-02-16
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR structure and dynamics of the Specifier Loop domain from the Bacillus subtilis tyrS T box leader RNA.
Nucleic Acids Res., 38, 2010
5BMP
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BU of 5bmp by Molmil
Crystal Structure of Phosphoglucomutase from Xanthomonas citri complexed with glucose-1-phosphate
Descriptor: 1-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, Phosphoglucomutase
Authors:Goto, L.S, Pereira, H.M, Novo Mansur, M.T.M.
Deposit date:2015-05-22
Release date:2016-06-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and functional characterization of the phosphoglucomutase from Xanthomonas citri subsp. citri.
Biochim.Biophys.Acta, 1864, 2016
4DN8
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Structure of porcine surfactant protein D neck and carbohydrate recognition domain complexed with mannose
Descriptor: CALCIUM ION, Pulmonary surfactant-associated protein D, beta-D-mannopyranose
Authors:van Eijk, M, Rynkiewicz, M.J, White, M.R, Hartshorn, K.L, Zou, X, Schulten, K, Luo, D, Crouch, E.C, Cafarella, T.M, Head, J.F, Haagsman, H.P, Seaton, B.A.
Deposit date:2012-02-08
Release date:2012-06-20
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A Unique Sugar-binding Site Mediates the Distinct Anti-influenza Activity of Pig Surfactant Protein D.
J.Biol.Chem., 287, 2012
5BMN
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BU of 5bmn by Molmil
Crystal Structure of APO form of Phosphoglucomutase from Xanthomonas citri
Descriptor: MAGNESIUM ION, Phosphoglucomutase
Authors:Goto, L.S, Pereira, H.M, Novo Mansur, M.T.M, Brandao-Neto, J.
Deposit date:2015-05-22
Release date:2016-06-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:Structural and functional characterization of the phosphoglucomutase from Xanthomonas citri subsp. citri.
Biochim.Biophys.Acta, 1864, 2016
5B6C
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BU of 5b6c by Molmil
Structural Details of Ufd1 binding to p97
Descriptor: Peptide from Ubiquitin fusion degradation protein 1 homolog, Transitional endoplasmic reticulum ATPase
Authors:Le, L.T.M, Yang, J.K.
Deposit date:2016-05-26
Release date:2017-01-04
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural Details of Ufd1 Binding to p97 and Their Functional Implications in ER-Associated Degradation
PLoS ONE, 11, 2016
2KNL
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Structure of the trimethylene N2-dG:N2-dG interstrand cross-link in the 5'-GpC-3' sequence context
Descriptor: DNA (5'-D(*TP*CP*CP*GP*CP*GP*GP*A)-3'), PROPANE
Authors:Huang, H, Dooley, P.A, Harris, C.M, Harris, T.M, Stone, M.P.
Deposit date:2009-08-26
Release date:2009-09-29
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Differential base stacking interactions induced by trimethylene interstrand DNA cross-links in the 5'-CpG-3' and 5'-GpC-3' sequence contexts.
Chem.Res.Toxicol., 22, 2009
5BZ5
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BU of 5bz5 by Molmil
Crystal structure of the RNA-binding domain of yeast Puf5p bound to AMN1 RNA
Descriptor: RNA (5'-R(*UP*GP*UP*AP*AP*CP*UP*UP*UP*A)-3'), Suppressor protein MPT5
Authors:Qiu, C, Hall, T.M.T.
Deposit date:2015-06-11
Release date:2015-09-23
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:RNA regulatory networks diversified through curvature of the PUF protein scaffold.
Nat Commun, 6, 2015
5BZV
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Crystal structure of the RNA-binding domain of yeast Puf5p bound to SMX2 RNA
Descriptor: RNA (5'-R(*UP*GP*UP*AP*CP*UP*AP*UP*A)-3'), Suppressor protein MPT5
Authors:Qiu, C, Hall, T.M.T.
Deposit date:2015-06-11
Release date:2015-09-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.354 Å)
Cite:RNA regulatory networks diversified through curvature of the PUF protein scaffold.
Nat Commun, 6, 2015
2KNK
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Structure of the trimethylene N2-dG:N2-dG interstrand cross-link in 5'-CpG-3' sequence context
Descriptor: DNA (5'-D(*AP*GP*GP*CP*GP*CP*CP*T)-3'), PROPANE
Authors:Huang, H, Dooley, P.A, Harris, C.M, Harris, T.M, Stone, M.P.
Deposit date:2009-08-26
Release date:2009-09-29
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Differential base stacking interactions induced by trimethylene interstrand DNA cross-links in the 5'-CpG-3' and 5'-GpC-3' sequence contexts.
Chem.Res.Toxicol., 22, 2009
2KUM
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BU of 2kum by Molmil
Solution structure of the human chemokine CCL27
Descriptor: C-C motif chemokine 27
Authors:Kirkpatrick, J.P, Jansma, A, Hsu, A, Handel, T.M, Nietlispach, D.
Deposit date:2010-02-22
Release date:2010-03-02
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:NMR analysis of the structure, dynamics, and unique oligomerization properties of the chemokine CCL27.
J.Biol.Chem., 285, 2010
7COK
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Crystal structure of ligand-free form of 5-ketofructose reductase of Gluconobacter sp. strain CHM43
Descriptor: 5-ketofructose reductase
Authors:Noda, S, Hodoya, Y, Nguyen, T.M, Kataoka, N, Adachi, O, Matsutani, M, Matsushita, K, Yakushi, T, Goto, M.
Deposit date:2020-08-04
Release date:2021-08-04
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The 5-Ketofructose Reductase of Gluconobacter sp. Strain CHM43 Is a Novel Class in the Shikimate Dehydrogenase Family.
J.Bacteriol., 203, 2021
7COL
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BU of 7col by Molmil
Crystal structure of 5-ketofructose reductase complexed with NADPH
Descriptor: 5-ketofructose reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Hodoya, Y, Noda, S, Nguyen, T.M, Kataoka, N, Adachi, O, Matsutani, M, Matsushita, K, Yakushi, T, Goto, M.
Deposit date:2020-08-04
Release date:2021-08-04
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The 5-Ketofructose Reductase of Gluconobacter sp. Strain CHM43 Is a Novel Class in the Shikimate Dehydrogenase Family.
J.Bacteriol., 203, 2021

223532

數據於2024-08-07公開中

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