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PDB: 12 件
4ZTU
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BU of 4ztu by Molmil
Structural basis for processivity and antiviral drug toxicity in human mitochondrial DNA replicase
分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*AP*AP*GP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3'), ...
著者Szymanski, M.R, Kuznestov, V.B, Shumate, C.K, Meng, Q, Lee, Y.-S, Patel, G, Patel, S.S, Yin, Y.W.
登録日2015-05-15
公開日2015-09-23
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.299 Å)
主引用文献Structural basis for processivity and antiviral drug toxicity in human mitochondrial DNA replicase
EMBO J., 34, 2015
4ZTZ
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BU of 4ztz by Molmil
Structural basis for processivity and antiviral drug toxicity in human mitochondrial DNA replicase
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*AP*AP*GP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3'), ...
著者Szymanski, M.R, Yin, Y.W.
登録日2015-05-15
公開日2015-09-23
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.442 Å)
主引用文献Structural basis for processivity and antiviral drug toxicity in human mitochondrial DNA replicase
EMBO J., 34, 2015
7R6V
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BU of 7r6v by Molmil
Human EXOG complexed with dRP-containing DNA
分子名称: DNA (5'-D(*CP*GP*CP*AP*CP*GP*TP*CP*AP*GP*AP*A)-3'), DNA (5'-D(*CP*TP*GP*AP*CP*GP*TP*GP*CP*G)-3'), MAGNESIUM ION, ...
著者Szymanski, M.R, Yin, Y.W.
登録日2021-06-23
公開日2022-08-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Human EXOG possesses strong AP hydrolysis activity
To Be Published
7R6T
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BU of 7r6t by Molmil
Human EXOG complexed with dRP-containing DNA
分子名称: DNA (5'-D(*CP*GP*CP*AP*CP*GP*TP*CP*AP*GP*A)-3'), DNA (5'-D(3DR)P*CP*TP*GP*AP*CP*GP*TP*GP*C)-3'), MAGNESIUM ION, ...
著者Szymanski, M.R, Yin, Y.W.
登録日2021-06-23
公開日2022-08-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Human EXOG possesses strong AP hydrolysis activity
To Be Published
5T4I
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BU of 5t4i by Molmil
A Novel domain in human EXOG converts apoptotic endonuclease to DNA-repair enzyme
分子名称: DNA (5'-D(*GP*CP*AP*CP*GP*TP*CP*AP*G)-3'), DNA (5'-D(P*CP*TP*GP*AP*CP*GP*TP*GP*C)-3'), MANGANESE (II) ION, ...
著者Szymanski, M.R, Yin, W.Y.
登録日2016-08-29
公開日2017-05-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.389 Å)
主引用文献A domain in human EXOG converts apoptotic endonuclease to DNA-repair exonuclease.
Nat Commun, 8, 2017
5T5C
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BU of 5t5c by Molmil
A Novel domain in human EXOG converts apoptotic endonuclease to DNA-repair enzyme
分子名称: DNA (5'-D(P*CP*TP*GP*AP*CP*GP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*CP*GP*TP*CP*AP*G)-3'), MAGNESIUM ION, ...
著者Szymanski, M.R, Yin, W.Y.
登録日2016-08-30
公開日2017-05-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.851 Å)
主引用文献A domain in human EXOG converts apoptotic endonuclease to DNA-repair exonuclease.
Nat Commun, 8, 2017
5T40
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BU of 5t40 by Molmil
A Novel domain in human EXOG converts apoptotic endonuclease to DNA-repair enzyme
分子名称: MAGNESIUM ION, Nuclease EXOG, mitochondrial, ...
著者Szymanski, M.R, Yin, W.Y.
登録日2016-08-27
公開日2017-05-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献A domain in human EXOG converts apoptotic endonuclease to DNA-repair exonuclease.
Nat Commun, 8, 2017
5T3V
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BU of 5t3v by Molmil
A Novel domain in human EXOG converts apoptotic endonuclease to DNA-repair enzyme
分子名称: MANGANESE (II) ION, Nuclease EXOG, mitochondrial, ...
著者Szymanski, M.R, Yin, W.Y.
登録日2016-08-26
公開日2017-05-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A domain in human EXOG converts apoptotic endonuclease to DNA-repair exonuclease.
Nat Commun, 8, 2017
9FXN
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BU of 9fxn by Molmil
Human mitochondrial nuclease EXOG (hEXOG)
分子名称: MAGNESIUM ION, Nuclease EXOG, mitochondrial
著者Karasinska, J.M, Szymanski, M.R.
登録日2024-07-02
公開日2024-07-31
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Human mitochondrial nuclease EXOG (hEXOG)
Nat Commun, 8, 2017
5C53
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BU of 5c53 by Molmil
Probing the Structural and Molecular Basis of Nucleotide Selectivity by Human Mitochondrial DNA Polymerase gamma
分子名称: 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE, DNA (26-MER), DNA (5'-D(*AP*AP*AP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3'), ...
著者Sohl, C.D, Szymanski, M.R, Mislak, A.C, Shumate, C.K, Amiralaei, S, Schinazi, R.F, Anderson, K.S, Yin, Y.W.
登録日2015-06-19
公開日2016-01-27
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.567 Å)
主引用文献Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase gamma.
Proc.Natl.Acad.Sci.USA, 112, 2015
5C51
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BU of 5c51 by Molmil
Probing the Structural and Molecular Basis of Nucleotide Selectivity by Human Mitochondrial DNA Polymerase gamma
分子名称: DNA, DNA (5'-D(*(AD)P*AP*AP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3'), DNA polymerase subunit gamma-1, ...
著者Sohl, C.D, Szymanski, M.R, Mislak, A.C, Shumate, C.K, Amiralaei, S, Schinazi, R.F, Anderson, K.S, Whitney, Y.Y.
登録日2015-06-19
公開日2016-05-11
最終更新日2016-05-18
実験手法X-RAY DIFFRACTION (3.426 Å)
主引用文献Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase gamma.
Proc.Natl.Acad.Sci.USA, 112, 2015
5C52
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BU of 5c52 by Molmil
Probing the Structural and Molecular Basis of Nucleotide Selectivity by Human Mitochondrial DNA Polymerase gamma
分子名称: DNA (26-MER), DNA (5'-D(*AP*AP*AP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3'), DNA polymerase subunit gamma-1, ...
著者Sohl, C.D, Szymanski, M.R, Mislak, A.C, Shumate, C.K, Amiralaei, S, Schinazi, R.F, Anderson, K.S, Yin, Y.W.
登録日2015-06-19
公開日2016-05-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.637 Å)
主引用文献Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase gamma.
Proc.Natl.Acad.Sci.USA, 112, 2015

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件を2024-07-31に公開中

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