2MDF
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1U0I
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![BU of 1u0i by Molmil](/molmil-images/mine/1u0i) | IAAL-E3/K3 heterodimer | Descriptor: | IAAL-E3, IAAL-K3 | Authors: | Lindhout, D.A, Litowski, J.R, Mercier, P, Hodges, R.S, Sykes, B.D. | Deposit date: | 2004-07-13 | Release date: | 2004-10-19 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR solution structure of a highly stable de novo heterodimeric coiled-coil Biopolymers, 75, 2004
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2MZP
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![BU of 2mzp by Molmil](/molmil-images/mine/2mzp) | Structure and dynamics of the acidosis-resistant a162H mutant of the switch region of troponin I bound to the regulatory domain of troponin C | Descriptor: | CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ... | Authors: | Pineda Sanabria, S.E, Robertson, I.M, Sykes, B.D. | Deposit date: | 2015-02-20 | Release date: | 2015-06-03 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure and Dynamics of the Acidosis-Resistant A162H Mutant of the Switch Region of Troponin I Bound to the Regulatory Domain of Troponin C. Biochemistry, 54, 2015
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1TRF
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![BU of 1trf by Molmil](/molmil-images/mine/1trf) | |
1RJT
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1SMG
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![BU of 1smg by Molmil](/molmil-images/mine/1smg) | CALCIUM-BOUND E41A MUTANT OF THE N-DOMAIN OF CHICKEN TROPONIN C, NMR, 40 STRUCTURES | Descriptor: | CALCIUM ION, TROPONIN C | Authors: | Gagne, S.M, Li, M.X, Sykes, B.D. | Deposit date: | 1997-02-04 | Release date: | 1997-08-12 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Mechanism of direct coupling between binding and induced structural change in regulatory calcium binding proteins. Biochemistry, 36, 1997
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1SPY
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![BU of 1spy by Molmil](/molmil-images/mine/1spy) | REGULATORY DOMAIN OF HUMAN CARDIAC TROPONIN C IN THE CALCIUM-FREE STATE, NMR, 40 STRUCTURES | Descriptor: | TROPONIN C | Authors: | Spyracopoulos, L, Li, M.X, Sia, S.K, Gagne, S.M, Chandra, M, Solaro, R.J, Sykes, B.D. | Deposit date: | 1997-07-14 | Release date: | 1998-09-16 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Calcium-induced structural transition in the regulatory domain of human cardiac troponin C. Biochemistry, 36, 1997
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1SDF
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![BU of 1sdf by Molmil](/molmil-images/mine/1sdf) | SOLUTION STRUCTURE OF STROMAL CELL-DERIVED FACTOR-1 (SDF-1), NMR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | STROMAL CELL-DERIVED FACTOR-1 | Authors: | Crump, M.P, Rajarathnam, K, Clark-Lewis, I, Sykes, B.D. | Deposit date: | 1997-11-15 | Release date: | 1998-01-28 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1. EMBO J., 16, 1997
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2N7L
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2KRD
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![BU of 2krd by Molmil](/molmil-images/mine/2krd) | Solution Structure of the Regulatory Domain of Human Cardiac Troponin C in Complex with the Switch Region of cardiac Troponin I and W7 | Descriptor: | CALCIUM ION, N-(6-AMINOHEXYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE, Troponin C, ... | Authors: | Oleszczuk, M, Robertson, I.M, Li, M.X, Sykes, B.D. | Deposit date: | 2009-12-16 | Release date: | 2010-02-16 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the regulatory domain of human cardiac troponin C in complex with the switch region of cardiac troponin I and W7: the basis of W7 as an inhibitor of cardiac muscle contraction. J.MOL.CELL.CARDIOL., 48, 2010
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2JT0
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![BU of 2jt0 by Molmil](/molmil-images/mine/2jt0) | Solution structure of F104W cardiac troponin C | Descriptor: | Troponin C, slow skeletal and cardiac muscles | Authors: | Wang, X, Mercier, P, Letourneau, P.-J, Sykes, B.D. | Deposit date: | 2007-07-17 | Release date: | 2008-05-27 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Effects of Phe-to-Trp mutation and fluorotryptophan incorporation on the solution structure of cardiac troponin C, and analysis of its suitability as a potential probe for in situ NMR studies. Protein Sci., 14, 2005
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2K3C
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![BU of 2k3c by Molmil](/molmil-images/mine/2k3c) | Structural and Functional Characterization of TM IX of the NHE1 Isoform of the Na+/H+ Exchanger | Descriptor: | TMIX peptide | Authors: | Reddy, T, Ding, J, Li, X, Sykes, B.D, Fliegel, L, Rainey, J.K. | Deposit date: | 2008-05-01 | Release date: | 2008-06-03 | Last modified: | 2020-02-19 | Method: | SOLUTION NMR | Cite: | Structural and Functional Characterization of Transmembrane Segment IX of the NHE1 Isoform of the Na+/H+ Exchanger. J.Biol.Chem., 283, 2008
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2KDH
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![BU of 2kdh by Molmil](/molmil-images/mine/2kdh) | The Solution Structure of Human Cardiac Troponin C in complex with the Green Tea Polyphenol; (-)-epigallocatechin-3-gallate | Descriptor: | (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate, CALCIUM ION, Troponin C, ... | Authors: | Robertson, I.M, Li, M.X, Sykes, B.D. | Deposit date: | 2009-01-09 | Release date: | 2009-06-16 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of human cardiac troponin C in complex with the green tea polyphenol, (-)-epigallocatechin 3-gallate J.Biol.Chem., 284, 2009
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2KGB
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![BU of 2kgb by Molmil](/molmil-images/mine/2kgb) | NMR solution of the regulatory domain cardiac F77W-Troponin C in complex with the cardiac Troponin I 144-163 switch peptide | Descriptor: | CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ... | Authors: | Mercier, P, Julien, O, Crane, M.L, Sykes, B.D. | Deposit date: | 2009-03-07 | Release date: | 2009-03-24 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The effect of the cosolvent trifluoroethanol on a tryptophan side chain orientation in the hydrophobic core of troponin C. Protein Sci., 18, 2009
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2KBV
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![BU of 2kbv by Molmil](/molmil-images/mine/2kbv) | Structural and functional analysis of TM XI of the NHE1 isoform of thE NA+/H+ exchanger | Descriptor: | Sodium/hydrogen exchanger 1 | Authors: | Lee, B.L, Li, X, Liu, Y, Sykes, B.D, Fliegel, L. | Deposit date: | 2008-12-09 | Release date: | 2009-01-27 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Structural and Functional Analysis of Transmembrane XI of the NHE1 Isoform of the Na+/H+ Exchanger J.Biol.Chem., 284, 2009
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2L8Q
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![BU of 2l8q by Molmil](/molmil-images/mine/2l8q) | Solution Structure of a control DNA Duplex | Descriptor: | DNA (5'-D(*CP*GP*CP*AP*TP*GP*CP*TP*AP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*GP*TP*AP*GP*CP*AP*TP*GP*CP*G)-3') | Authors: | Julien, O, Beadle, J.R, Magee, W.C, Chatterjee, S, Hostetler, K.Y, Evans, D.H, Sykes, B.D. | Deposit date: | 2011-01-22 | Release date: | 2011-02-23 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of a DNA duplex containing the potent anti-poxvirus agent cidofovir. J.Am.Chem.Soc., 133, 2011
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2L8P
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![BU of 2l8p by Molmil](/molmil-images/mine/2l8p) | Solution Structure of a DNA Duplex Containing the Potent Anti-Poxvirus Agent Cidofovir | Descriptor: | DNA (5'-D(*CP*GP*CP*AP*TP*GP*(L8P)P*TP*AP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*GP*TP*AP*GP*CP*AP*TP*GP*CP*G)-3') | Authors: | Julien, O, Beadle, J.R, Magee, W.C, Chatterjee, S, Hostetler, K.Y, Evans, D.H, Sykes, B.D. | Deposit date: | 2011-01-22 | Release date: | 2011-02-23 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of a DNA duplex containing the potent anti-poxvirus agent cidofovir. J.Am.Chem.Soc., 133, 2011
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2HTG
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![BU of 2htg by Molmil](/molmil-images/mine/2htg) | Structural and functional characterization of TM VII of the NHE1 isoform of the Na+/H+ exchanger | Descriptor: | NHE1 isoform of Na+/H+ exchanger 1 | Authors: | Rainey, J.K, Ding, J, Xu, C, Fliegel, L, Sykes, B.D. | Deposit date: | 2006-07-25 | Release date: | 2006-08-08 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Structural and functional characterization of transmembrane segment VII of the Na(+)/H(+) exchanger isoform 1 J.Biol.Chem., 281, 2006
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2JT3
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![BU of 2jt3 by Molmil](/molmil-images/mine/2jt3) | Solution Structure of F153W cardiac troponin C | Descriptor: | Troponin C | Authors: | Wang, X, Mercier, P, Letourneau, P, Sykes, B.D. | Deposit date: | 2007-07-18 | Release date: | 2007-07-31 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Effects of Phe-to-Trp mutation and fluorotryptophan incorporation on the solution structure of cardiac troponin C, and analysis of its suitability as a potential probe for in situ NMR studies. Protein Sci., 14, 2005
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2L1R
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![BU of 2l1r by Molmil](/molmil-images/mine/2l1r) | The structure of the calcium-sensitizer, dfbp-o, in complex with the N-domain of troponin C and the switch region of troponin I | Descriptor: | CALCIUM ION, Troponin C, Troponin I, ... | Authors: | Robertson, I.M, Sun, Y, Li, M.X, Sykes, B.D. | Deposit date: | 2010-08-03 | Release date: | 2010-08-18 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | A structural and functional perspective into the mechanism of Ca(2+)-sensitizers that target the cardiac troponin complex. J.MOL.CELL.CARDIOL., 49, 2010
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2L0E
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2JXL
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![BU of 2jxl by Molmil](/molmil-images/mine/2jxl) | Solution structure of cardiac N-domain troponin C mutant F77W-V82A | Descriptor: | CALCIUM ION, Troponin C, slow skeletal and cardiac muscles | Authors: | Julien, O, Sun, Y, Wang, X, Lindhout, D.A, Thiessen, A, Irving, M, Sykes, B.D. | Deposit date: | 2007-11-20 | Release date: | 2007-12-04 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Tryptophan Mutants of Cardiac Troponin C: 3D Structure, Troponin I Affinity, and in Situ Activity. Biochemistry, 47, 2008
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2JT8
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![BU of 2jt8 by Molmil](/molmil-images/mine/2jt8) | Solution structure of the F153-to-5-flurotryptophan mutant of human cardiac troponin C | Descriptor: | Troponin C, slow skeletal and cardiac muscles | Authors: | Wang, X, Mercier, P, Letourneau, P, Sykes, B.D. | Deposit date: | 2007-07-20 | Release date: | 2007-08-07 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Effects of Phe-to-Trp mutation and fluorotryptophan incorporation on the solution structure of cardiac troponin C, and analysis of its suitability as a potential probe for in situ NMR studies Protein Sci., 14, 2005
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2JTZ
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![BU of 2jtz by Molmil](/molmil-images/mine/2jtz) | Solution structure and chemical shift assignments of the F104-to-5-flurotryptophan mutant of cardiac troponin C | Descriptor: | Troponin C, slow skeletal and cardiac muscles | Authors: | Wang, X, Mercier, P, Letourneau, P, Sykes, B.D. | Deposit date: | 2007-08-10 | Release date: | 2007-08-28 | Last modified: | 2021-10-20 | Method: | SOLUTION NMR | Cite: | Effects of Phe-to-Trp mutation and fluorotryptophan incorporation on the solution structure of cardiac troponin C, and analysis of its suitability as a potential probe for in situ NMR studies Protein Sci., 14, 2005
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1ILO
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![BU of 1ilo by Molmil](/molmil-images/mine/1ilo) | NMR structure of a thioredoxin, MtH895, from the archeon Methanobacterium thermoautotrophicum strain delta H. | Descriptor: | conserved hypothetical protein MtH895 | Authors: | Bhattacharyya, S, Habibi-Nazhad, B, Slupsky, C.M, Sykes, B.D, Wishart, D.S, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2001-05-08 | Release date: | 2001-11-14 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Identification of a novel archaebacterial thioredoxin: determination of function through structure. Biochemistry, 41, 2002
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