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PDB: 349 件

4S2I
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CTX-M-15 in complex with Avibactam
分子名称: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase
著者King, D.T, Strynadka, N.C.J.
登録日2015-01-20
公開日2015-02-25
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Molecular Mechanism of Avibactam-Mediated beta-Lactamase Inhibition.
ACS Infect Dis, 1, 2015
4S2K
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OXA-48 in complex with Avibactam at pH 7.5
分子名称: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase
著者King, D.T, Strynadka, N.C.J.
登録日2015-01-20
公開日2015-02-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Molecular Mechanism of Avibactam-Mediated beta-Lactamase Inhibition.
ACS Infect Dis, 1, 2015
4S2P
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Crystal structure of unbound OXA-48
分子名称: Beta-lactamase
著者King, D.T, Strynadka, N.C.J.
登録日2015-01-21
公開日2015-02-25
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Molecular Mechanism of Avibactam-Mediated beta-Lactamase Inhibition.
ACS Infect Dis, 1, 2015
2P2V
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Crystal structure analysis of monofunctional alpha-2,3-sialyltransferase Cst-I from Campylobacter jejuni
分子名称: 1,2-ETHANEDIOL, Alpha-2,3-sialyltransferase, CHLORIDE ION, ...
著者Chiu, C.P, Lairson, L.L, Gilbert, M, Wakarchuk, W.W, Withers, S.G, Strynadka, N.C.
登録日2007-03-07
公開日2007-07-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Analysis of the alpha-2,3-Sialyltransferase Cst-I from Campylobacter jejuni in Apo and Substrate-Analogue Bound Forms.
Biochemistry, 46, 2007
2P56
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Crystal structure of alpha-2,3-sialyltransferase from Campylobacter jejuni in apo form
分子名称: 1,2-ETHANEDIOL, Alpha-2,3-sialyltransferase
著者Chiu, C.P, Lairson, L.L, Gilbert, M, Wakarchuk, W.W, Withers, S.G, Strynadka, N.C.
登録日2007-03-14
公開日2007-07-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Analysis of the alpha-2,3-Sialyltransferase Cst-I from Campylobacter jejuni in Apo and Substrate-Analogue Bound Forms.
Biochemistry, 46, 2007
6W5Q
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Structure of the globular C-terminal domain of P. aeruginosa LpoP
分子名称: Peptidoglycan synthase activator LpoP, SULFATE ION, TRIETHYLENE GLYCOL
著者Caveney, N.A, Robb, C.S, Simorre, J.P, Strynadka, N.C.J.
登録日2020-03-13
公開日2020-05-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the Peptidoglycan Synthase Activator LpoP in Pseudomonas aeruginosa.
Structure, 28, 2020
8V31
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Structure of Alistipes sp. 3-Keto-2-hydroxy-glucal-hydratase AL2
分子名称: Glycosyl hydrolase, MAGNESIUM ION
著者Lazarski, A.C, Worrall, L.J, Strynadka, N.C.J.
登録日2023-11-25
公開日2024-06-19
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献An alternative broad-specificity pathway for glycan breakdown in bacteria
To Be Published
6XFK
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Crystal structure of the type III secretion system pilotin-secretin complex InvH-InvG
分子名称: SULFATE ION, Type 3 secretion system pilotin, Type 3 secretion system secretin
著者Majewski, D.D, Okon, M, Heinkel, F, Robb, C.S, Vuckovic, M, McIntosh, L.P, Strynadka, N.C.J.
登録日2020-06-15
公開日2020-09-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Characterization of the Pilotin-Secretin Complex from the Salmonella enterica Type III Secretion System Using Hybrid Structural Methods.
Structure, 29, 2021
6XFU
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PmtCD peptide exporter basket domain
分子名称: ABC transporter ATP-binding protein, THIOCYANATE ION
著者Zeytuni, N, Strynadka, N.C.J, Alexander, J.A.N.
登録日2020-06-16
公開日2020-10-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural insight into the Staphylococcus aureus ATP-driven exporter of virulent peptide toxins
Sci Adv, 6, 2020
1B12
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CRYSTAL STRUCTURE OF TYPE 1 SIGNAL PEPTIDASE FROM ESCHERICHIA COLI IN COMPLEX WITH A BETA-LACTAM INHIBITOR
分子名称: PHOSPHATE ION, SIGNAL PEPTIDASE I, prop-2-en-1-yl (2S)-2-[(2S,3R)-3-(acetyloxy)-1-oxobutan-2-yl]-2,3-dihydro-1,3-thiazole-4-carboxylate
著者Paetzel, M, Dalbey, R, Strynadka, N.C.J.
登録日1999-11-24
公開日1999-12-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of a bacterial signal peptidase in complex with a beta-lactam inhibitor.
Nature, 396, 1998
5CUL
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crystal structure of the PscU C-terminal domain
分子名称: Translocation protein in type III secretion
著者Bergeron, J.R.C, Strynadka, N.C.J.
登録日2015-07-24
公開日2015-12-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Structure of a Type 3 Secretion System (T3SS) Ruler Protein Suggests a Molecular Mechanism for Needle Length Sensing.
J.Biol.Chem., 291, 2016
5CUK
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Crystal structure of the PscP SS domain
分子名称: GLYCEROL, Ruler protein
著者Bergeron, J.R.C, Strynadka, N.C.J.
登録日2015-07-24
公開日2015-12-02
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Structure of a Type 3 Secretion System (T3SS) Ruler Protein Suggests a Molecular Mechanism for Needle Length Sensing.
J.Biol.Chem., 291, 2016
6PEE
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InvG secretin domain beta-barrel from Salmonella SPI-1 injectisome NC-base
分子名称: LAURYL DIMETHYLAMINE-N-OXIDE, Protein InvG
著者Hu, J, Worrall, L.J, Strynadka, N.C.J.
登録日2019-06-20
公開日2019-10-23
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
8V34
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Crystal structure of S. aureus TarK N-terminal domain
分子名称: CDP-glycerol glycerophosphotransferase family protein
著者Li, F.K.K, Strynadka, N.C.J.
登録日2023-11-26
公開日2024-04-03
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Cryo-EM analysis of S. aureus TarL, a polymerase in wall teichoic acid biogenesis central to virulence and antibiotic resistance.
Sci Adv, 10, 2024
8V33
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Crystal structure of S. aureus TarL N-terminal domain
分子名称: SUCCINIC ACID, Teichoic acid ribitol-phosphate polymerase TarL
著者Li, F.K.K, Strynadka, N.C.J.
登録日2023-11-26
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Cryo-EM analysis of S. aureus TarL, a polymerase in wall teichoic acid biogenesis central to virulence and antibiotic resistance.
Sci Adv, 10, 2024
6PEM
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Focussed refinement of InvGN0N1:SpaPQR:PrgHK from Salmonella SPI-1 injectisome NC-base
分子名称: Lipoprotein PrgK, Protein InvG, Protein PrgH, ...
著者Hu, J, Worrall, L.J, Strynadka, N.C.J.
登録日2019-06-20
公開日2019-10-23
最終更新日2020-01-08
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
8VA1
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S. aureus TarL H300N in complex with CDP-ribitol (single tetramer)
分子名称: CDP-ribitol, Teichoic acid ribitol-phosphate polymerase TarL
著者Li, F.K.K, Worrall, L.J, Strynadka, N.C.J.
登録日2023-12-10
公開日2024-04-03
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM analysis of S. aureus TarL, a polymerase in wall teichoic acid biogenesis central to virulence and antibiotic resistance.
Sci Adv, 10, 2024
4X6L
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Crystal structure of S. aureus TarM in complex with UDP
分子名称: TarM, URIDINE-5'-DIPHOSPHATE
著者Worrall, L.J, Sobhanifar, S, Gruninger, R.J, Strynadka, N.C.
登録日2014-12-08
公開日2015-02-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid alpha-glycosyltransferase.
Proc.Natl.Acad.Sci.USA, 112, 2015
6Q15
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Structure of the Salmonella SPI-1 injectisome needle complex
分子名称: Lipoprotein PrgK, Protein InvG, Protein PrgH, ...
著者Hu, J, Worrall, L.J, Strynadka, N.C.J.
登録日2019-08-02
公開日2019-10-23
最終更新日2020-01-08
実験手法ELECTRON MICROSCOPY (5.15 Å)
主引用文献T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
6Q14
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Structure of the Salmonella SPI-1 injectisome NC-base
分子名称: Lipoprotein PrgK, Protein InvG, Protein PrgH, ...
著者Hu, J, Worrall, L.J, Strynadka, N.C.J.
登録日2019-08-02
公開日2019-10-23
最終更新日2020-01-08
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
4X7P
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Crystal structure of apo S. aureus TarM
分子名称: SULFATE ION, TarM
著者Worrall, L.J, Sobhanifar, S, Gruninger, R.J, Strynadka, N.C.
登録日2014-12-09
公開日2015-02-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid alpha-glycosyltransferase.
Proc.Natl.Acad.Sci.USA, 112, 2015
4X7M
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Crystal structure of S. aureus TarM G117R mutant in complex with UDP and UDP-GlcNAc
分子名称: TarM, URIDINE-5'-DIPHOSPHATE, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
著者Worrall, L.J, Sobhanifar, S, Strynadka, N.C.
登録日2014-12-09
公開日2015-03-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid alpha-glycosyltransferase.
Proc.Natl.Acad.Sci.USA, 112, 2015
4X7R
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Crystal structure of S. aureus TarM G117R mutant in complex with Fondaparinux, alpha-GlcNAc-glycerol and UDP
分子名称: (2S)-2,3-dihydroxypropyl 2-acetamido-2-deoxy-alpha-D-glucopyranoside, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, TarM, ...
著者Worrall, L.J, Sobhanifar, S, Strynadka, N.C.
登録日2014-12-09
公開日2015-02-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid alpha-glycosyltransferase.
Proc.Natl.Acad.Sci.USA, 112, 2015
6Q16
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Focussed refinement of InvGN0N1:PrgHK:SpaPQR:PrgIJ from Salmonella SPI-1 injectisome NC-base
分子名称: Lipoprotein PrgK, Protein InvG, Protein PrgH, ...
著者Hu, J, Worrall, L.J, Strynadka, N.C.J.
登録日2019-08-02
公開日2019-10-23
最終更新日2020-01-15
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
8VBW
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Structure of the monofunctional Staphylococcus aureus PBP1 in its beta-lactam (Ertapenem) inhibited form
分子名称: (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, Penicillin-binding protein 1
著者Bon, C.G, Lee, J, Caveney, N.A, Strynadka, N.C.J.
登録日2023-12-12
公開日2024-05-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and kinetic analysis of the monofunctional Staphylococcus aureus PBP1.
J.Struct.Biol., 216, 2024

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