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PDB: 190 件

7SQ5
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Designed trefoil knot protein, variant 3
分子名称: Designed trefoil knot protein, variant 3, SODIUM ION
著者Takushi, B, Doyle, L, Stoddard, B.L, Bradley, P.
登録日2021-11-04
公開日2022-11-09
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.205 Å)
主引用文献De novo design of knotted tandem repeat proteins.
Nat Commun, 14, 2023
4YIS
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BU of 4yis by Molmil
Crystal Structure of LAGLIDADG Meganuclease I-CpaMI Bound to Uncleaved DNA
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DNA (28-MER), ...
著者Hallinan, J.P, Kaiser, B.K, Stoddard, B.L.
登録日2015-03-02
公開日2016-03-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity.
Structure, 24, 2016
4YY2
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Computationally designed left-handed alpha/alpha toroid with 3 repeats in space group P212121
分子名称: SODIUM ION, dTor_3x33L
著者Hallinan, J.P, Bradley, P, Stoddard, B.L.
登録日2015-03-23
公開日2015-12-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.854 Å)
主引用文献Rational design of alpha-helical tandem repeat proteins with closed architectures.
Nature, 528, 2015
1IDC
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BU of 1idc by Molmil
ISOCITRATE DEHYDROGENASE FROM E.COLI (MUTANT K230M), STEADY-STATE INTERMEDIATE COMPLEX DETERMINED BY LAUE CRYSTALLOGRAPHY
分子名称: 2-OXALOSUCCINIC ACID, ISOCITRATE DEHYDROGENASE, MAGNESIUM ION
著者Bolduc, J.M, Dyer, D.H, Scott, W.G, Singer, P, Sweet, R.M, Koshland Junior, D.E, Stoddard, B.L.
登録日1995-01-18
公開日1996-03-08
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase.
Science, 268, 1995
1IDF
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BU of 1idf by Molmil
ISOCITRATE DEHYDROGENASE K230M MUTANT APO ENZYME
分子名称: ISOCITRATE DEHYDROGENASE
著者Bolduc, J.M, Dyer, D.H, Scott, W.G, Singer, P, Sweet, R.M, Koshland Junior, D.E, Stoddard, B.L.
登録日1995-01-18
公開日1996-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase.
Science, 268, 1995
1IDD
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BU of 1idd by Molmil
ISOCITRATE DEHYDROGENASE Y160F MUTANT APO ENZYME
分子名称: ISOCITRATE DEHYDROGENASE
著者Lee, M.E, Dyer, D.H, Klein, O.D, Bolduc, J.M, Stoddard, B.L, Koshland Junior, D.E.
登録日1995-01-18
公開日1996-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase.
Science, 268, 1995
4YIT
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BU of 4yit by Molmil
Crystal Structure of LAGLIDADG Meganuclease I-AabMI Bound to Uncleaved DNA
分子名称: CALCIUM ION, DNA (25-MER), DNA (25MER), ...
著者Hallinan, J.P, Stoddard, B.L.
登録日2015-03-02
公開日2016-03-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity.
Structure, 24, 2016
4YHX
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BU of 4yhx by Molmil
Crystal Structure of LAGLIDADG Meganuclease I-GpeMI Bound to Uncleaved DNA
分子名称: CALCIUM ION, DNA (27-MER), Ribosomal protein 3/homing endonuclease-like fusion protein
著者Hallinan, J.P, Kaiser, B.K, Stoddard, B.L.
登録日2015-02-27
公開日2016-03-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity.
Structure, 24, 2016
4Z1Z
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BU of 4z1z by Molmil
Crystal Structure of Meganuclease I-SmaMI Bound to Uncleaveable DNA with a TTCT Central Four
分子名称: CALCIUM ION, DNA (28-MER), GLYCEROL, ...
著者Hallinan, J.P, Stoddard, B.L.
登録日2015-03-27
公開日2016-03-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity.
Structure, 24, 2016
4Z20
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BU of 4z20 by Molmil
Crystal Structure of Meganuclease I-SmaMI Bound to Uncleaveable DNA with a TTGT Central Four
分子名称: CALCIUM ION, DNA (26-MER), GLYCEROL, ...
著者Hallinan, J.P, Stoddard, B.L.
登録日2015-03-27
公開日2016-03-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity.
Structure, 24, 2016
4YXX
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Computationally designed left-handed alpha/alpha toroid with 6 repeats
分子名称: dTor_6x35L
著者Doyle, L, Bolduc, J, Stoddard, B.L, Bradley, P.
登録日2015-03-23
公開日2015-12-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Rational design of alpha-helical tandem repeat proteins with closed architectures.
Nature, 528, 2015
4YY5
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BU of 4yy5 by Molmil
Computationally designed left-handed alpha/alpha toroid with 3 repeats in space group P43212
分子名称: dTor_3x33L
著者Hallinan, J.P, Bradley, P, Stoddard, B.L.
登録日2015-03-23
公開日2015-12-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Rational design of alpha-helical tandem repeat proteins with closed architectures.
Nature, 528, 2015
4YXZ
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BU of 4yxz by Molmil
Computationally designed left-handed alpha/alpha toroid with 9 repeats
分子名称: dTor_9x31L
著者Doyle, L, Stoddard, B.L, Bradley, P.
登録日2015-03-23
公開日2015-12-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.496 Å)
主引用文献Rational design of alpha-helical tandem repeat proteins with closed architectures.
Nature, 528, 2015
1K6W
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BU of 1k6w by Molmil
The Structure of Escherichia coli Cytosine Deaminase
分子名称: Cytosine Deaminase, FE (III) ION
著者Ireton, G.C, McDermott, G, Black, M.E, Stoddard, B.L.
登録日2001-10-17
公開日2002-02-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The structure of Escherichia coli cytosine deaminase.
J.Mol.Biol., 315, 2002
4YXY
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BU of 4yxy by Molmil
Computationally designed left-handed alpha/alpha toroid with 9 repeats; two linked rings of 12 repeats each structure
分子名称: dTor_9x31L
著者Doyle, L, Stoddard, B.L, Bradley, P.
登録日2015-03-23
公開日2015-12-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.203 Å)
主引用文献Rational design of alpha-helical tandem repeat proteins with closed architectures.
Nature, 528, 2015
1K70
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The Structure of Escherichia coli Cytosine Deaminase bound to 4-Hydroxy-3,4-Dihydro-1H-Pyrimidin-2-one
分子名称: 4-HYDROXY-3,4-DIHYDRO-1H-PYRIMIDIN-2-ONE, Cytosine Deaminase, FE (III) ION
著者Ireton, G.C, McDermott, G, Black, M.E, Stoddard, B.L.
登録日2001-10-17
公開日2002-02-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structure of Escherichia coli cytosine deaminase.
J.Mol.Biol., 315, 2002
1LTQ
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BU of 1ltq by Molmil
CRYSTAL STRUCTURE OF T4 POLYNUCLEOTIDE KINASE
分子名称: ADENOSINE-5'-DIPHOSPHATE, DIMETHYL SULFOXIDE, POLYNUCLEOTIDE KINASE
著者Galburt, E.A, Pelletier, J, Wilson, G, Stoddard, B.L.
登録日2002-05-20
公開日2002-10-09
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Structure of a tRNA repair enzyme and molecular biology workhorse: T4 polynucleotide kinase.
Structure, 10, 2002
5TGQ
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BU of 5tgq by Molmil
Restriction-modification system Type II R.SwaI, DNA free
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, CALCIUM ION, ...
著者Shen, B.W, stoddard, B.L.
登録日2016-09-28
公開日2016-12-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献DNA recognition by the SwaI restriction endonuclease involves unusual distortion of an 8 base pair A:T-rich target.
Nucleic Acids Res., 45, 2017
5TGX
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BU of 5tgx by Molmil
Restriction/modification system-Type II R-SwaI complexed with partially cleaved DNA
分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
著者Shen, B.W, Stoddard, B.L.
登録日2016-09-28
公開日2016-12-21
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献DNA recognition by the SwaI restriction endonuclease involves unusual distortion of an 8 base pair A:T-rich target.
Nucleic Acids Res., 45, 2017
1P6O
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BU of 1p6o by Molmil
The crystal structure of yeast cytosine deaminase bound to 4(R)-hydroxyl-3,4-dihydropyrimidine at 1.14 angstroms.
分子名称: 4-HYDROXY-3,4-DIHYDRO-1H-PYRIMIDIN-2-ONE, ACETIC ACID, CALCIUM ION, ...
著者Ireton, G.C, Black, M.E, Stoddard, B.L.
登録日2003-04-29
公開日2003-08-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献The 1.14 a crystal structure of yeast Cytosine deaminase. Evolution of nucleotide salvage enzymes and implications for genetic chemotherapy.
Structure, 11, 2003
5TH3
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BU of 5th3 by Molmil
Restriction/modification system-Type II R.SwaI cleaved DNA complex
分子名称: 1,2-ETHANEDIOL, ACETATE ION, DNA (cleaved 25-MER, ...
著者Shen, B.W, Stoddard, B.L.
登録日2016-09-29
公開日2016-12-21
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献DNA recognition by the SwaI restriction endonuclease involves unusual distortion of an 8 base pair A:T-rich target.
Nucleic Acids Res., 45, 2017
5THG
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BU of 5thg by Molmil
Engineered variant of I-OnuI meganuclease targeting the HIV CCR5 gene; harbors 43 point mutations relative to wild-type I-OnuI
分子名称: CALCIUM ION, DNA (29-MER), GLYCEROL, ...
著者Hallinan, J.P, Stoddard, B.L.
登録日2016-09-29
公開日2017-05-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.106 Å)
主引用文献The structural basis of altered gene specificity resulting from meganuclease and MegaTAL engineering
to be published
1MOW
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BU of 1mow by Molmil
E-DreI
分子名称: 5'-D(*CP*CP*AP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*AP*GP*TP*TP*CP*CP*GP*GP*CP*G)-3', 5'-D(*CP*GP*CP*CP*GP*GP*AP*AP*CP*TP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*TP*GP*G)-3', GLYCEROL, ...
著者Chevalier, B.S, Kortemme, T, Chadsey, M.S, Baker, D, Monnat Jr, R.J, Stoddard, B.L.
登録日2002-09-10
公開日2002-11-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Design, Activity and Structure of a Highly Specific Artificial Endonuclease
Mol.Cell, 10, 2002
1Q33
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Crystal structure of human ADP-ribose pyrophosphatase NUDT9
分子名称: ADP-ribose pyrophosphatase, SULFATE ION, beta-D-glucopyranose
著者Shen, B.W, Perraud, A.L, Scharenberg, A, Stoddard, B.L.
登録日2003-07-28
公開日2003-09-30
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献The Crystal Structure and Mutational Analysis of Human NUDT9
J.Mol.Biol., 332, 2003
1N3F
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Crystal structure of I-CreI bound to a palindromic DNA sequence II (palindrome of right side of wildtype DNA target sequence)
分子名称: 5'-D(*CP*GP*AP*AP*AP*CP*TP*GP*TP*CP*TP*CP*GP*A)-3', 5'-D(P*GP*AP*CP*AP*GP*TP*TP*TP*CP*G-3'), CALCIUM ION, ...
著者Chevalier, B, Turmel, M, Lemieux, C, Monnat, R.J, Stoddard, B.L.
登録日2002-10-28
公開日2003-06-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Flexible DNA Target Site Recognition by Divergent Homing Endonuclease Isoschizomers I-CreI and I-MsoI
J.Mol.Biol., 329, 2003

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