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PDB: 20 件
2IEP
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Crystal structure of immunoglobulin-like domains 1 and 2 of the receptor tyrosine kinase MuSK
分子名称: Muscle-specific kinase receptor, SULFATE ION
著者Stiegler, A.L, Burden, S.J, Hubbard, S.R.
登録日2006-09-19
公開日2006-11-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.205 Å)
主引用文献Crystal Structure of the Agrin-responsive Immunoglobulin-like Domains 1 and 2 of the Receptor Tyrosine Kinase MuSK
J.Mol.Biol., 364, 2006
6D4G
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N-GTPase domain of p190RhoGAP-A
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rho GTPase-activating protein 35
著者Stiegler, A.L, Boggon, T.J.
登録日2018-04-18
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The N-Terminal GTPase Domain of p190RhoGAP Proteins Is a PseudoGTPase.
Structure, 26, 2018
4TKN
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Structure of the SNX17 FERM domain bound to the second NPxF motif of KRIT1
分子名称: Krev interaction trapped protein 1, Sorting nexin-17
著者Stiegler, A.L, Zhang, R, Liu, W, Boggon, T.J.
登録日2014-05-27
公開日2014-07-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Determinants for Binding of Sorting Nexin 17 (SNX17) to the Cytoplasmic Adaptor Protein Krev Interaction Trapped 1 (KRIT1).
J.Biol.Chem., 289, 2014
5U4U
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pseudoGTPase domain (pG1) of p190RhoGAP-A
分子名称: MALONATE ION, MGC81300 protein, SODIUM ION
著者Stiegler, A.L, Boggon, T.J.
登録日2016-12-06
公開日2017-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献p190RhoGAP proteins contain pseudoGTPase domains.
Nat Commun, 8, 2017
5U4V
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pseudoGTPase domain (pG1) of p190RhoGAP-B
分子名称: Rho GTPase-activating protein 5
著者Stiegler, A.L, Boggon, T.J.
登録日2016-12-06
公開日2017-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献p190RhoGAP proteins contain pseudoGTPase domains.
Nat Commun, 8, 2017
3HKL
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Crystal Structure of the Frizzled-like Cysteine-rich Domain of MuSK
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Muscle, skeletal receptor tyrosine protein kinase
著者Stiegler, A.L, Hubbard, S.R.
登録日2009-05-24
公開日2009-08-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the frizzled-like cysteine-rich domain of the receptor tyrosine kinase MuSK.
J.Mol.Biol., 393, 2009
7TPB
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p120RasGAP SH3 domain in complex with DLC1 RhoGAP domain
分子名称: Ras GTPase-activating protein 1, Rho GTPase-activating protein 7
著者Stiegler, A.L, Boggon, T.J, Chau, J.E, Vish, K.J.
登録日2022-01-25
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献SH3 domain regulation of RhoGAP activity: Crosstalk between p120RasGAP and DLC1 RhoGAP.
Nat Commun, 13, 2022
8DGQ
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Crystal structure of p120RasGAP SH2-SH3-SH2 in complex with p190RhoGAP doubly phosphorylated peptide
分子名称: MALONATE ION, Ras GTPase-activating protein 1, Rho GTPase-activating protein 35
著者Stiegler, A.L, Vish, K.J, Boggon, T.J.
登録日2022-06-24
公開日2022-11-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Tandem engagement of phosphotyrosines by the dual SH2 domains of p120RasGAP.
Structure, 30, 2022
4EDN
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Crystal structure of beta-parvin CH2 domain in complex with paxillin LD1 motif
分子名称: Beta-parvin, Paxillin, SULFATE ION
著者Stiegler, A.L, Draheim, K.M, Li, X, Chayen, N.E, Calderwood, D.A, Boggon, T.J.
登録日2012-03-27
公開日2012-08-08
最終更新日2013-06-19
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for paxillin binding and focal adhesion targeting of beta-parvin.
J.Biol.Chem., 287, 2012
4EDL
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Crystal structure of beta-parvin CH2 domain
分子名称: 1,2-ETHANEDIOL, Beta-parvin
著者Stiegler, A.L, Draheim, K.M, Li, X, Chayen, N.E, Calderwood, D.A, Boggon, T.J.
登録日2012-03-27
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for paxillin binding and focal adhesion targeting of beta-parvin.
J.Biol.Chem., 287, 2012
4EDM
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Crystal structure of beta-parvin CH2 domain
分子名称: 1,2-ETHANEDIOL, Beta-parvin
著者Stiegler, A.L, Draheim, K.M, Li, X, Chayen, N.E, Calderwood, D.A, Boggon, T.J.
登録日2012-03-27
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for paxillin binding and focal adhesion targeting of beta-parvin.
J.Biol.Chem., 287, 2012
4HI9
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1.2 structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain collected at wavelength 0.91974
分子名称: IODIDE ION, Integrin-linked protein kinase, LIM and senescent cell antigen-like-containing domain protein 1, ...
著者Stiegler, A.L, Jakoncic, J, Stojanoff, V, Chiswell, B.P, Calderwood, D.A, Boggon, T.J.
登録日2012-10-11
公開日2013-12-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.203 Å)
主引用文献1.2 structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain collected at wavelength 0.91974
To be Published
4HI8
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Structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain collected at high energy, wavelength 0.32800
分子名称: Integrin-linked protein kinase, LIM and senescent cell antigen-like-containing domain protein 1, PHOSPHATE ION, ...
著者Stiegler, A.L, Jakoncic, J, Stojanoff, V, Chiswell, B.P, Calderwood, D.A, Boggon, T.J.
登録日2012-10-11
公開日2013-12-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.203 Å)
主引用文献Structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain collected at high energy, wavelength 0.32800
To be Published
6WAX
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C-terminal SH2 domain of p120RasGAP
分子名称: 1,2-ETHANEDIOL, Ras GTPase-activating protein 1, SULFATE ION
著者Jaber Chehayeb, R, Wang, J, Stiegler, A.L, Boggon, T.J.
登録日2020-03-26
公開日2020-06-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The GTPase-activating protein p120RasGAP has an evolutionarily conserved "FLVR-unique" SH2 domain.
J.Biol.Chem., 295, 2020
4WJ7
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CCM2 PTB domain in complex with KRIT1 NPxY/F3
分子名称: KRIT1 NPxY/F3, Malcavernin
著者Fisher, O.S, Liu, W, Zhang, R, Stiegler, A.L, Boggon, T.J.
登録日2014-09-29
公開日2014-12-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.753 Å)
主引用文献Structural Basis for the Disruption of the Cerebral Cavernous Malformations 2 (CCM2) Interaction with Krev Interaction Trapped 1 (KRIT1) by Disease-associated Mutations.
J.Biol.Chem., 290, 2015
6WAY
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BU of 6way by Molmil
C-terminal SH2 domain of p120RasGAP in complex with p190RhoGAP phosphotyrosine peptide
分子名称: Ras GTPase-activating protein 1, Rho GTPase-activating protein 35
著者Jaber Chehayeb, R, Wang, J, Stiegler, A.L, Boggon, T.J.
登録日2020-03-26
公開日2020-06-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The GTPase-activating protein p120RasGAP has an evolutionarily conserved "FLVR-unique" SH2 domain.
J.Biol.Chem., 295, 2020
3IXE
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BU of 3ixe by Molmil
Structural basis of competition between PINCH1 and PINCH2 for binding to the ankyrin repeat domain of integrin-linked kinase
分子名称: Integrin-linked protein kinase, LIM and senescent cell antigen-like-containing domain protein 2, ZINC ION
著者Chiswell, B.P, Stiegler, A.L, Boggon, T.J, Calderwood, D.A.
登録日2009-09-03
公開日2009-12-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of competition between PINCH1 and PINCH2 for binding to the ankyrin repeat domain of integrin-linked kinase.
J.Struct.Biol., 170, 2010
6PXC
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N-Terminal SH2 domain of the p120RasGAP bound to a p190RhoGAP phosphotyrosine peptide
分子名称: Ras GTPase-activating protein 1, phosphopeptide of p190RhoGAP
著者Jaber Chehayeb, R, Stiegler, A.L, Boggon, T.J.
登録日2019-07-25
公開日2019-12-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structures of p120RasGAP N-terminal SH2 domain in its apo form and in complex with a p190RhoGAP phosphotyrosine peptide.
Plos One, 14, 2019
6PXB
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N-Terminal SH2 domain of the p120RasGAP
分子名称: Ras GTPase-activating protein 1
著者Jaber Chehayeb, R, Stiegler, A.L, Boggon, T.J.
登録日2019-07-25
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.747 Å)
主引用文献Crystal structures of p120RasGAP N-terminal SH2 domain in its apo form and in complex with a p190RhoGAP phosphotyrosine peptide.
Plos One, 14, 2019
7UGB
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Crystal structure of rat ERK2 complexed with docking peptide from ISG20
分子名称: Interferon-stimulated gene 20 kDa protein, Mitogen-activated protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Torres Robles, J, Stiegler, A.L, Boggon, T.J, Turk, B.E.
登録日2022-03-24
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献To be determined
To Be Published

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