3MK8
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3T5V
| Sac3:Thp1:Sem1 complex | Descriptor: | 26S proteasome complex subunit SEM1, Nuclear mRNA export protein SAC3, Nuclear mRNA export protein THP1 | Authors: | Stewart, M, Ellisdon, A.M. | Deposit date: | 2011-07-28 | Release date: | 2012-02-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis for the assembly and nucleic acid binding of the TREX-2 transcription-export complex. Nat.Struct.Mol.Biol., 19, 2012
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3FWB
| Sac3:Sus1:Cdc31 complex | Descriptor: | Cell division control protein 31, Nuclear mRNA export protein SAC3, Protein SUS1 | Authors: | Stewart, M, Jani, D. | Deposit date: | 2009-01-17 | Release date: | 2009-04-14 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Sus1, Cdc31, and the Sac3 CID region form a conserved interaction platform that promotes nuclear pore association and mRNA export. Mol.Cell, 33, 2009
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3KND
| TPX2:importin-alpha complex | Descriptor: | Importin subunit alpha-2, SULFATE ION, Targeting protein for Xklp2 | Authors: | Stewart, M. | Deposit date: | 2009-11-12 | Release date: | 2010-03-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.151 Å) | Cite: | Novel binding of the mitotic regulator TPX2 (target protein for Xenopus kinesin-like protein 2) to importin-alpha. J.Biol.Chem., 285, 2010
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3RAN
| CANINE GDP-RAN Q69L MUTANT | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (GTP-BINDING NUCLEAR PROTEIN RAN) | Authors: | Stewart, M, Kent, H.M, Mccoy, A.J. | Deposit date: | 1998-10-19 | Release date: | 1998-12-02 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The structure of the Q69L mutant of GDP-Ran shows a major conformational change in the switch II loop that accounts for its failure to bind nuclear transport factor 2 (NTF2). J.Mol.Biol., 284, 1998
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4C31
| Nup1:Sac3:Sus1 complex | Descriptor: | NUCLEAR MRNA EXPORT PROTEIN SAC3, NUCLEOPORIN NUP1, PROTEIN SUS1 | Authors: | Stewart, M, Jani, D. | Deposit date: | 2013-08-21 | Release date: | 2014-04-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Basis for Binding the Trex2 Complex to Nuclear Pores, Gal1 Localisation and Mrna Export. Nucleic Acids Res., 42, 2014
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4DHX
| ENY2:GANP complex | Descriptor: | 80 kDa MCM3-associated protein, Enhancer of yellow 2 transcription factor homolog | Authors: | Stewart, M, Jani, D. | Deposit date: | 2012-01-30 | Release date: | 2012-06-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export. Nucleic Acids Res., 40, 2012
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1DEJ
| CRYSTAL STRUCTURE OF A DICTYOSTELIUM/TETRAHYMENA CHIMERA ACTIN (MUTANT 646: Q228K/T229A/A230Y/A231K/S232E/E360H) IN COMPLEX WITH HUMAN GELSOLIN SEGMENT 1 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, CHIMERIC ACTIN, ... | Authors: | Matsuura, Y, Stewart, M, Kawamoto, M, Kamiya, N, Saeki, K, Yasunaga, T, Wakabayashi, T. | Deposit date: | 1999-11-15 | Release date: | 2000-03-01 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for the higher Ca(2+)-activation of the regulated actin-activated myosin ATPase observed with Dictyostelium/Tetrahymena actin chimeras. J.Mol.Biol., 296, 2000
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1AR0
| NUCLEAR TRANSPORT FACTOR 2 (NTF2) E42K MUTANT | Descriptor: | NUCLEAR TRANSPORT FACTOR 2 | Authors: | Mccoy, A.J, Stewart, M.J. | Deposit date: | 1997-08-08 | Release date: | 1997-12-24 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Nuclear protein import is decreased by engineered mutants of nuclear transport factor 2 (NTF2) that do not bind GDP-Ran. J.Mol.Biol., 272, 1997
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1ASK
| NUCLEAR TRANSPORT FACTOR 2 (NTF2) H66A MUTANT | Descriptor: | NUCLEAR TRANSPORT FACTOR 2 | Authors: | Mccoy, A.J, Stewart, M.J. | Deposit date: | 1997-08-11 | Release date: | 1998-01-28 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Nuclear protein import is decreased by engineered mutants of nuclear transport factor 2 (NTF2) that do not bind GDP-Ran. J.Mol.Biol., 272, 1997
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1C0G
| CRYSTAL STRUCTURE OF 1:1 COMPLEX BETWEEN GELSOLIN SEGMENT 1 AND A DICTYOSTELIUM/TETRAHYMENA CHIMERA ACTIN (MUTANT 228: Q228K/T229A/A230Y/E360H) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, PROTEIN (CHIMERIC ACTIN), ... | Authors: | Matsuura, Y, Stewart, M, Kawamoto, M, Kamiya, N, Saeki, K, Yasunaga, T, Wakabayashi, T. | Deposit date: | 1999-07-16 | Release date: | 2000-03-01 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for the higher Ca(2+)-activation of the regulated actin-activated myosin ATPase observed with Dictyostelium/Tetrahymena actin chimeras. J.Mol.Biol., 296, 2000
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1C0F
| CRYSTAL STRUCTURE OF DICTYOSTELIUM CAATP-ACTIN IN COMPLEX WITH GELSOLIN SEGMENT 1 | Descriptor: | ACTIN, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ... | Authors: | Matsuura, Y, Stewart, M, Kawamoto, M, Kamiya, N, Saeki, K, Yasunaga, T, Wakabayashi, T. | Deposit date: | 1999-07-16 | Release date: | 2000-03-01 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for the higher Ca(2+)-activation of the regulated actin-activated myosin ATPase observed with Dictyostelium/Tetrahymena actin chimeras J.Mol.Biol., 296, 2000
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4WWU
| Structure of Mex67:Mtr2 | Descriptor: | ZINC ION, mRNA export factor MEX67, mRNA transport regulator MTR2 | Authors: | Aibara, S, Valkov, E, Stewart, M. | Deposit date: | 2014-11-12 | Release date: | 2015-02-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.301 Å) | Cite: | Domain organization within the nuclear export factor Mex67:Mtr2 generates an extended mRNA binding surface. Nucleic Acids Res., 43, 2015
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4WP6
| Structure of the Mex67 LRR domain from Chaetomium thermophilum | Descriptor: | mRNA export protein | Authors: | Aibara, S, Valkov, E, Lamers, M, Stewart, M. | Deposit date: | 2014-10-17 | Release date: | 2015-07-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural characterization of the principal mRNA-export factor Mex67-Mtr2 from Chaetomium thermophilum. Acta Crystallogr.,Sect.F, 71, 2015
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4WP2
| Chaetomium Mex67 UBA domain | Descriptor: | Putative mRNA export protein | Authors: | Aibara, S, Stewart, M. | Deposit date: | 2014-10-17 | Release date: | 2015-07-15 | Last modified: | 2017-09-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural characterization of the principal mRNA-export factor Mex67-Mtr2 from Chaetomium thermophilum. Acta Crystallogr.,Sect.F, 71, 2015
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4X2M
| Structure of Mtr2 | Descriptor: | Mtr2 | Authors: | Aibara, S, Valkov, E, Stewart, M. | Deposit date: | 2014-11-26 | Release date: | 2015-07-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural characterization of the principal mRNA-export factor Mex67-Mtr2 from Chaetomium thermophilum. Acta Crystallogr.,Sect.F, 71, 2015
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4XM4
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4WPM
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4WP5
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2MSP
| MAJOR SPERM PROTEIN, BETA ISOFORM, ENGINEERED C59S/T90C MUTANT, PUTATIVE SUBFILAMENT STRUCTURE, PH 8.5 | Descriptor: | MAJOR SPERM PROTEIN | Authors: | Bullock, T.L, Mccoy, A.J, Stewart, M. | Deposit date: | 1997-12-19 | Release date: | 1998-04-15 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural basis for amoeboid motility in nematode sperm. Nat.Struct.Biol., 5, 1998
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6OPC
| Cdc48 Hexamer in a complex with substrate and Shp1(Ubx Domain) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cell division control protein 48, ... | Authors: | Cooney, I, Han, H, Stewart, M, Carson, R.H, Hansen, D, Price, J.C, Hill, C.P, Shen, P.S. | Deposit date: | 2019-04-24 | Release date: | 2019-07-10 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structure of the Cdc48 segregase in the act of unfolding an authentic substrate. Science, 365, 2019
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4WYK
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4X2H
| Sac3N peptide bound to Mex67:Mtr2 | Descriptor: | Putative mRNA export protein, Putative uncharacterized protein, SER-SER-VAL-PHE-GLY-ALA-PRO-ALA | Authors: | Aibara, S, Valkov, E, Stewart, M. | Deposit date: | 2014-11-26 | Release date: | 2015-06-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Characterization of the Chaetomium thermophilum TREX-2 Complex and its Interaction with the mRNA Nuclear Export Factor Mex67:Mtr2. Structure, 23, 2015
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1UN0
| Crystal Structure of Yeast Karyopherin (Importin) alpha in complex with a Nup2p N-terminal fragment | Descriptor: | IMPORTIN ALPHA SUBUNIT, NUCLEOPORIN NUP2 | Authors: | Matsuura, Y, Lange, A, Harreman, M.T, Corbett, A.H, Stewart, M. | Deposit date: | 2003-09-03 | Release date: | 2003-10-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural Basis for Nup2P Function in Cargo Release and Karyopherin Recycling in Nuclear Import Embo J., 22, 2003
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2Z5I
| Crystal structure of the head-to-tail junction of tropomyosin | Descriptor: | General control protein GCN4 and Tropomyosin alpha-1 chain, MAGNESIUM ION, Tropomyosin alpha-1 chain and General control protein GCN4 | Authors: | Murakami, K, Nozawa, K, Tomii, K, Kudou, N, Igarashi, N, Shirakihara, Y, Wakatsuki, S, Stewart, M, Yasunaga, T, Wakabayashi, T. | Deposit date: | 2007-07-12 | Release date: | 2008-04-22 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for tropomyosin overlap in thin (actin) filaments and the generation of a molecular swivel by troponin-T Proc.Natl.Acad.Sci.USA, 105, 2008
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