4EIB
| Crystal Structure of Circular Permuted CBM21 (CP90) Gives Insight into the Altered Selectivity on Carbohydrate Binding. | 分子名称: | ACETATE ION, AMMONIUM ION, CHLORIDE ION, ... | 著者 | Stephen, P, Cheng, K.C, Lyu, P.C. | 登録日 | 2012-04-05 | 公開日 | 2012-12-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Crystal structure of circular permuted RoCBM21 (CP90): dimerisation and proximity of binding sites Plos One, 7, 2012
|
|
5HIE
| BRAF Kinase domain b3aC loop deletion mutant in complex with dabrafenib | 分子名称: | Dabrafenib, Serine/threonine-protein kinase B-raf | 著者 | Whalen, D.M, Foster, S.A, Ozen, A, Wongchenko, M, Yin, J, Schaefer, G, Mayfield, J, Chmielecki, J, Stephens, P, Albacker, L, Yan, Y, Song, K, Hatzivassiliou, G, Eigenbrot, C, Yu, C, Shaw, A.S, Manning, G, Skelton, N.J, Hymowitz, S.G, Malek, S. | 登録日 | 2016-01-11 | 公開日 | 2016-04-06 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Activation Mechanism of Oncogenic Deletion Mutations in BRAF, EGFR, and HER2. Cancer Cell, 29, 2016
|
|
5HID
| BRAF Kinase domain b3aC loop deletion mutant in complex with AZ628 | 分子名称: | 3-(2-cyanopropan-2-yl)-N-{4-methyl-3-[(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}benzamide, DI(HYDROXYETHYL)ETHER, Serine/threonine-protein kinase B-raf | 著者 | Whalen, D.M, Foster, S.A, Ozen, A, Wongchenko, M, Yin, J, Schaefer, G, Mayfield, J, Chmielecki, J, Stephens, P, Albacker, L, Yan, Y, Song, K, Hatzivassiliou, G, Eigenbrot, C, Yu, C, Shaw, A.S, Manning, G, Skelton, N.J, Hymowitz, S.G, Malek, S. | 登録日 | 2016-01-11 | 公開日 | 2016-04-06 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Activation Mechanism of Oncogenic Deletion Mutations in BRAF, EGFR, and HER2. Cancer Cell, 29, 2016
|
|
5HI2
| BRAF Kinase domain b3aC loop deletion mutant in complex with sorafenib | 分子名称: | 4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE, Serine/threonine-protein kinase B-raf | 著者 | Whalen, D.M, Foster, S.A, Ozen, A, Wongchenko, M, Yin, J, Schaefer, G, Mayfield, J, Chmielecki, J, Stephens, P, Albacker, L, Yan, Y, Song, K, Hatzivassiliou, G, Eigenbrot, C, Yu, C, Shaw, A.S, Manning, G, Skelton, N.J, Hymowitz, S.G, Malek, S. | 登録日 | 2016-01-11 | 公開日 | 2016-04-06 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.512 Å) | 主引用文献 | Activation Mechanism of Oncogenic Deletion Mutations in BRAF, EGFR, and HER2. Cancer Cell, 29, 2016
|
|
2KH2
| Solution structure of a scFv-IL-1B complex | 分子名称: | Interleukin-1 beta, scFv | 著者 | Wilkinson, I.C, Hall, C.J, Veverka, V, Muskett, F.W, Stephens, P.E, Taylor, R.J, Henry, A.J, Carr, M.D. | 登録日 | 2009-03-23 | 公開日 | 2009-09-08 | 最終更新日 | 2022-03-16 | 実験手法 | SOLUTION NMR | 主引用文献 | High resolution NMR-based model for the structure of a scFv-IL-1beta complex: potential for NMR as a key tool in therapeutic antibody design and development. J.Biol.Chem., 284, 2009
|
|
1FU2
| FIRST PROTEIN STRUCTURE DETERMINED FROM X-RAY POWDER DIFFRACTION DATA | 分子名称: | CHLORIDE ION, INSULIN, A CHAIN, ... | 著者 | Von Dreele, R.B, Stephens, P.W, Blessing, R.H, Smith, G.D. | 登録日 | 2000-09-13 | 公開日 | 2000-10-16 | 最終更新日 | 2018-10-03 | 実験手法 | POWDER DIFFRACTION | 主引用文献 | The first protein crystal structure determined from high-resolution X-ray powder diffraction data: a variant of T3R3 human insulin-zinc complex produced by grinding. Acta Crystallogr.,Sect.D, 56, 2000
|
|
1FUB
| FIRST PROTEIN STRUCTURE DETERMINED FROM X-RAY POWDER DIFFRACTION DATA | 分子名称: | CHLORIDE ION, INSULIN, A CHAIN, ... | 著者 | Von Dreele, R.B, Stephens, P.W, Blessing, R.H, Smith, G.D. | 登録日 | 2000-09-14 | 公開日 | 2000-10-16 | 最終更新日 | 2018-10-03 | 実験手法 | POWDER DIFFRACTION | 主引用文献 | The first protein crystal structure determined from high-resolution X-ray powder diffraction data: a variant of T3R3 human insulin-zinc complex produced by grinding. Acta Crystallogr.,Sect.D, 56, 2000
|
|
5B63
| Crystal structures of E.coli arginyl-tRNA synthetase (ArgRS) in complex with substrate tRNA(Arg) | 分子名称: | Arginine--tRNA ligase, tRNA-Arg | 著者 | Zhou, M, Ye, S, Stephen, P, Zhang, R, Wang, E.D, Giege, R, Lin, S.X. | 登録日 | 2016-05-24 | 公開日 | 2017-05-31 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structures of E.coli arginyl-tRNA synthetase (ArgRS) in complex with substrate tRNA(Arg) To Be Published
|
|
5YYN
| Crystal structures of E.coli arginyl-trna synthetase (argrs) in complex with substrate TRNA(Arg) | 分子名称: | Arginine--tRNA ligase, TRNA | 著者 | Zhou, M, Ye, S, Stephen, P, Zhang, R.G, Wang, E.D, Giege, R, Lin, S.X. | 登録日 | 2017-12-10 | 公開日 | 2018-12-12 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal Structures Of E.Coli Arginyl-Trna Synthetase (Argrs) In Complex With Substrates To Be Published
|
|
5YYM
| Crystal structures of E.coli arginyl-trna synthetase (argrs) in complex with substrate Arg | 分子名称: | ARGININE, Arginine--tRNA ligase | 著者 | Zhou, M, Ye, S, Stephen, P, Zhang, R.G, Wang, E.D, Giege, R, Lin, S.X. | 登録日 | 2017-12-10 | 公開日 | 2018-12-12 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structures Of E.Coli Arginyl-Trna Synthetase (Argrs) In Complex With Substrates To Be Published
|
|
6MNC
| CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 COMPLEXED WITH ESTRONE | 分子名称: | (9beta,13alpha)-3-hydroxyestra-1,3,5(10)-trien-17-one, DI(HYDROXYETHYL)ETHER, Estradiol 17-beta-dehydrogenase 1 | 著者 | Li, T, Stephen, P, Zhu, D.W, Lin, S.X. | 登録日 | 2018-10-01 | 公開日 | 2019-04-03 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structures of human 17 beta-hydroxysteroid dehydrogenase type 1 complexed with estrone and NADP+reveal the mechanism of substrate inhibition. Febs J., 286, 2019
|
|