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PDB: 54 results

4AAB
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BU of 4aab by Molmil
Crystal structure of the mutant D75N I-CreI in complex with its wild- type target (The four central bases, 2NN region, are composed by GTAC from 5' to 3')
Descriptor: 10MER DNA 5'-D(*GP*AP*CP*GP*TP*TP*TP*TP*GP*AP)-3', 14MER DNA 5'-D(*TP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*AP*CP)-3', DNA ENDONUCLEASE I-CREI, ...
Authors:Molina, R, Redondo, P, Stella, S, Marenchino, M, D'Abramo, M, Gervasio, F.L, Epinat, J.C, Valton, J, Grizot, S, Duchateau, P, Prieto, J, Montoya, G.
Deposit date:2011-12-01
Release date:2012-05-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Non-Specific Protein-DNA Interactions Control I-Crei Target Binding and Cleavage.
Nucleic Acids Res., 40, 2012
5MGA
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BU of 5mga by Molmil
Structure of the Cpf1 endonuclease R-loop complex after DNA cleavage
Descriptor: CRISPR-associated endonuclease Cpf1, DNA (26-MER), DNA (5'-D(P*CP*GP*TP*TP*AP*GP*AP*GP*AP*AP*GP*T)-3'), ...
Authors:Montoya, G, Stella, S.
Deposit date:2016-11-21
Release date:2017-06-21
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage.
Nature, 546, 2017
8AXB
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BU of 8axb by Molmil
Cryo-EM structure of Cas12k-sgRNA binary complex (type V-K CRISPR-associated transposon)
Descriptor: Cas12k, sgRNA
Authors:Tenjo-Castano, F, Sofos, N, Stella, S, Molina, R, Pape, T, Lopez-Mendez, B, Stutzke, L.S, Temperini, P, Montoya, G.
Deposit date:2022-08-31
Release date:2024-04-10
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Conformational landscape of the type V-K CRISPR-associated transposon integration assembly.
Mol.Cell, 84, 2024
8AXA
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BU of 8axa by Molmil
Cryo-EM structure of shCas12k-sgRNA-dsDNA ternary complex (type V-K CRISPR-associated transposon)
Descriptor: Cas12k, DNA non-target strand, DNA target strand, ...
Authors:Tenjo-Castano, F, Sofos, N, Stella, S, Fuglsang, A, Pape, T, Mesa, P, Stutzke, L.S, Temperini, P, Montoya, G.
Deposit date:2022-08-31
Release date:2024-04-10
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Conformational landscape of the type V-K CRISPR-associated transposon integration assembly.
Mol.Cell, 84, 2024
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