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PDB: 283 results

3CMA
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BU of 3cma by Molmil
The structure of CCA and CCA-Phe-Cap-Bio bound to the large ribosomal subunit of Haloarcula marismortui
Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
Authors:Simonovic, M, Steitz, T.A.
Deposit date:2008-03-21
Release date:2008-09-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Peptidyl-CCA deacylation on the ribosome promoted by induced fit and the O3'-hydroxyl group of A76 of the unacylated A-site tRNA.
Rna, 14, 2008
1KQS
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BU of 1kqs by Molmil
The Haloarcula marismortui 50S Complexed with a Pretranslocational Intermediate in Protein Synthesis
Descriptor: 23S RRNA, 5S RRNA, 6-AMINOHEXANOIC ACID, ...
Authors:Schmeing, T.M, Seila, A.C, Hansen, J.L, Freeborn, B, Soukup, J.K, Scaringe, S.A, Strobel, S.A, Moore, P.B, Steitz, T.A.
Deposit date:2002-01-07
Release date:2002-02-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A pre-translocational intermediate in protein synthesis observed in crystals of enzymatically active 50S subunits.
Nat.Struct.Biol., 9, 2002
1K9M
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BU of 1k9m by Molmil
Co-crystal structure of tylosin bound to the 50S ribosomal subunit of Haloarcula marismortui
Descriptor: 23S RRNA, 5S RRNA, CADMIUM ION, ...
Authors:Hansen, J.L, Ippolito, J.A, Ban, N, Nissen, P, Moore, P.B, Steitz, T.A.
Deposit date:2001-10-29
Release date:2002-07-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structures of four macrolide antibiotics bound to the large ribosomal subunit.
Mol.Cell, 10, 2002
1KD1
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BU of 1kd1 by Molmil
Co-crystal Structure of Spiramycin bound to the 50S Ribosomal Subunit of Haloarcula marismortui
Descriptor: 23S RRNA, 5S RRNA, CADMIUM ION, ...
Authors:Hansen, J.L, Ippolito, J.A, Ban, N, Nissen, P, Moore, P.B, Steitz, T.A.
Deposit date:2001-11-12
Release date:2002-07-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structures of four macrolide antibiotics bound to the large ribosomal subunit.
Mol.Cell, 10, 2002
1M1K
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BU of 1m1k by Molmil
Co-crystal structure of azithromycin bound to the 50S ribosomal subunit of Haloarcula marismortui
Descriptor: 23S RRNA, 5S RRNA, AZITHROMYCIN, ...
Authors:Hansen, J.L, Ippolito, J.A, Ban, N, Nissen, P, Moore, P.B, Steitz, T.A.
Deposit date:2002-06-19
Release date:2002-07-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The structures of four macrolide antibiotics bound to the large ribosomal subunit.
Mol.Cell, 10, 2002
1GTS
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BU of 1gts by Molmil
STRUCTURAL BASIS FOR TRANSFER RNA AMINOACEYLATION BY ESCHERICHIA COLI GLUTAMINYL-TRNA SYNTHETASE
Descriptor: ADENOSINE MONOPHOSPHATE, PROTEIN (GLUTAMINYL-TRNA SYNTHETASE (E.C.6.1.1.18)), TRNAGLN
Authors:Perona, J.J, Steitz, T.A, Rould, M.A.
Deposit date:1993-09-15
Release date:1995-02-07
Last modified:2017-02-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for transfer RNA aminoacylation by Escherichia coli glutaminyl-tRNA synthetase.
Biochemistry, 32, 1993
3CME
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BU of 3cme by Molmil
The Structure of CA and CCA-PHE-CAP-BIO Bound to the Large Ribosomal Subunit of Haloarcula Marismortui
Descriptor: 50S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
Authors:Simonovic, M, Steitz, T.A.
Deposit date:2008-03-21
Release date:2008-09-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Peptidyl-CCA deacylation on the ribosome promoted by induced fit and the O3'-hydroxyl group of A76 of the unacylated A-site tRNA.
Rna, 14, 2008
3CPW
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BU of 3cpw by Molmil
The structure of the antibiotic LINEZOLID bound to the large ribosomal subunit of HALOARCULA MARISMORTUI
Descriptor: 23S RIBOSOMAL RNA, 5'-R(*CP*CP*AP*(PHE)*(ACA))-3', 50S ribosomal protein L10E, ...
Authors:Ippolito, J.A, Kanyo, Z.K, Wang, D, Franceschi, F.J, Moore, P.B, Steitz, T.A, Duffy, E.M.
Deposit date:2008-04-01
Release date:2008-07-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit
J.Med.Chem., 51, 2008
1VQ9
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BU of 1vq9 by Molmil
The structure of CCA-PHE-CAP-BIO and the antibiotic sparsomycin bound to the large ribosomal subunit of haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*CP*CP*AP*(PHE)*(ACA))-3', 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1VQL
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The structure of the transition state analogue "DCSN" bound to the large ribosomal subunit of haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*CP*CP*(PPU)*(TSE)*(DA)*CP*C)-3', 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1QVF
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BU of 1qvf by Molmil
Structure of a deacylated tRNA minihelix bound to the E site of the large ribosomal subunit of Haloarcula marismortui
Descriptor: 23S ribosomal rna, 50S RIBOSOMAL PROTEIN L10E, 50S ribosomal protein L13P, ...
Authors:Schmeing, T.M, Moore, P.B, Steitz, T.A.
Deposit date:2003-08-27
Release date:2003-11-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of deacylated tRNA mimics bound to the E site of the large ribosomal subunit
RNA, 9, 2003
1Q82
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BU of 1q82 by Molmil
Crystal Structure of CC-Puromycin bound to the A-site of the 50S ribosomal subunit
Descriptor: 23S ribosomal rna, 50S ribosomal protein L13P, 50S ribosomal protein L14P, ...
Authors:Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A.
Deposit date:2003-08-20
Release date:2003-10-07
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:Structural Insights Into Peptide Bond Formation
Proc.Natl.Acad.Sci.USA, 99, 2002
1Q7Y
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BU of 1q7y by Molmil
Crystal Structure of CCdAP-Puromycin bound at the Peptidyl transferase center of the 50S ribosomal subunit
Descriptor: 23S ribosomal rna, 50S ribosomal protein L13P, 50S ribosomal protein L14P, ...
Authors:Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A.
Deposit date:2003-08-20
Release date:2003-10-07
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Insights Into Peptide Bond Formation
Proc.Natl.Acad.Sci.USA, 99, 2002
1QVG
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BU of 1qvg by Molmil
Structure of CCA oligonucleotide bound to the tRNA binding sites of the large ribosomal subunit of Haloarcula marismortui
Descriptor: 23S ribosomal rna, 50S RIBOSOMAL PROTEIN L10E, 50S ribosomal protein L13P, ...
Authors:Schmeing, T.M, Moore, P.B, Steitz, T.A.
Deposit date:2003-08-27
Release date:2003-11-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of deacylated tRNA mimics bound to the E site of the large ribosomal subunit
RNA, 9, 2003
1Q86
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BU of 1q86 by Molmil
Crystal structure of CCA-Phe-cap-biotin bound simultaneously at half occupancy to both the A-site and P-site of the the 50S ribosomal Subunit.
Descriptor: 23S ribosomal rna, 50S ribosomal protein L13P, 50S ribosomal protein L14P, ...
Authors:Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A.
Deposit date:2003-08-20
Release date:2003-10-07
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into peptide bond formation.
Proc.Natl.Acad.Sci.USA, 99, 2002
1Q81
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BU of 1q81 by Molmil
Crystal Structure of minihelix with 3' puromycin bound to A-site of the 50S ribosomal subunit.
Descriptor: 23S ribosomal rna, 50S ribosomal protein L13P, 50S ribosomal protein L14P, ...
Authors:Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A.
Deposit date:2003-08-20
Release date:2003-10-07
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural Insights into Peptide Bond Formation
Proc.Natl.Acad.Sci.USA, 99, 2002
1S72
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BU of 1s72 by Molmil
REFINED CRYSTAL STRUCTURE OF THE HALOARCULA MARISMORTUI LARGE RIBOSOMAL SUBUNIT AT 2.4 ANGSTROM RESOLUTION
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L10e, 50S ribosomal protein L11P, ...
Authors:Klein, D.J, Schmeing, T.M, Moore, P.B, Steitz, T.A.
Deposit date:2004-01-28
Release date:2004-06-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Roles of Ribosomal Proteins in the Structure, Assembly and Evolution of the Large Ribosomal Subunit
J.Mol.Biol., 340, 2004
397D
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BU of 397d by Molmil
A 1.3 A RESOLUTION CRYSTAL STRUCTURE OF THE HIV-1 TRANS-ACTIVATION RESPONSE REGION RNA STEM REVEALS A METAL ION-DEPENDENT BULGE CONFORMATION
Descriptor: CALCIUM ION, RNA (5'-R(*GP*CP*UP*CP*UP*CP*UP*GP*GP*CP*CP*C)-3'), RNA (5'-R(*GP*GP*CP*CP*AP*GP*AP*UP*CP*UP*GP*AP*GP*CP*G)-3')
Authors:Ippolito, J.A, Steitz, T.A.
Deposit date:1998-04-30
Release date:1998-09-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:A 1.3-A resolution crystal structure of the HIV-1 trans-activation response region RNA stem reveals a metal ion-dependent bulge conformation.
Proc.Natl.Acad.Sci.USA, 95, 1998
1VQM
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BU of 1vqm by Molmil
The structure of the transition state analogue "DAN" bound to the large ribosomal subunit of haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*CP*CP*(PPU)P*(PO2)P*(DA)P*C*C)-3'), 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1VQK
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BU of 1vqk by Molmil
The structure of CCDA-PHE-CAP-BIO bound to the a site of the ribosomal subunit of haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*CP*CP*(DA)*(PHE)*(ACA))-3', 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1VQ8
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BU of 1vq8 by Molmil
The structure of CCDA-PHE-CAP-BIO and the antibiotic sparsomycin bound to the large ribosomal subunit of haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*CP*CP*(DA)*(PHE)*(ACA))-3', 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1VQO
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BU of 1vqo by Molmil
The structure of CCPMN bound to the large ribosomal subunit haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*CP*CP*(PPU))-3', 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1VQ4
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BU of 1vq4 by Molmil
The structure of the transition state analogue "DAA" bound to the large ribosomal subunit of Haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*CP*CP*(5AA)P*(2OP)P*(PO2)P*(DA)P*C*C)-3'), 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1VQ5
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BU of 1vq5 by Molmil
The structure of the transition state analogue "RAA" bound to the large ribosomal subunit of haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-D(*(DC)P*(DC)P*(5AA)P*(2OP)P*(PO2)P*AP*C*C)-3'), 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005
1VQP
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BU of 1vqp by Molmil
The structure of the transition state analogue "RAP" bound to the large ribosomal subunit of haloarcula marismortui
Descriptor: 23S ribosomal rna, 5'-R(*(DC)P*(DC)P*(PPU)*(LOF)P*(PO2)P*AP*C*C)-3', 50S RIBOSOMAL PROTEIN L10E, ...
Authors:Schmeing, T.M, Steitz, T.A.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural Insights into the Roles of Water and the 2' Hydroxyl of the P Site tRNA in the Peptidyl Transferase Reaction.
Mol.Cell, 20, 2005

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