6DND
 
 | | Crystal structure of wild-type (WT) human Glutamate oxaloacetate transaminase 1 (GOT1) | | 分子名称: | Aspartate aminotransferase, cytoplasmic, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Assar, Z, Holt, M.C, Stein, A.J, Lairson, L, Lyssiotis, C.A. | | 登録日 | 2018-06-06 | | 公開日 | 2018-11-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Biochemical Characterization and Structure-Based Mutational Analysis Provide Insight into the Binding and Mechanism of Action of Novel Aspartate Aminotransferase Inhibitors.
Biochemistry, 57, 2018
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6DNB
 | | Crystal structure of T110A:S256A mutant human Glutamate oxaloacetate transaminase 1 (GOT1) | | 分子名称: | Aspartate aminotransferase, cytoplasmic, GLYCEROL, ... | | 著者 | Assar, Z, Holt, M.C, Stein, A.J, Lairson, L, Lyssiotis, C.A. | | 登録日 | 2018-06-06 | | 公開日 | 2018-11-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Biochemical Characterization and Structure-Based Mutational Analysis Provide Insight into the Binding and Mechanism of Action of Novel Aspartate Aminotransferase Inhibitors.
Biochemistry, 57, 2018
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2KOG
 | | lipid-bound synaptobrevin solution NMR structure | | 分子名称: | Vesicle-associated membrane protein 2 | | 著者 | Ellena, J.F, Liang, B, Wiktor, M, Stein, A, Cafiso, D.S, Jahn, R, Tamm, L.K. | | 登録日 | 2009-09-22 | | 公開日 | 2009-12-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Dynamic structure of lipid-bound synaptobrevin suggests a nucleation-propagation mechanism for trans-SNARE complex formation.
Proc.Natl.Acad.Sci.USA, 106, 2009
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5IPR
 | | Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 3 | | 分子名称: | Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a | | 著者 | Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E. | | 登録日 | 2016-03-09 | | 公開日 | 2016-04-20 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (14.1 Å) | | 主引用文献 | Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
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5IPQ
 | | Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 2 | | 分子名称: | Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a | | 著者 | Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E. | | 登録日 | 2016-03-09 | | 公開日 | 2016-04-20 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (13.5 Å) | | 主引用文献 | Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
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4WZ0
 | | Crystal structure of U-box 1 of LubX / LegU2 / Lpp2887 from Legionella pneumophila str. Paris | | 分子名称: | E3 ubiquitin-protein ligase LubX | | 著者 | Stogios, P.J, Quaile, A.T, Skarina, T, Stein, A, Di Leo, R, Yim, V, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2014-11-18 | | 公開日 | 2015-01-14 | | 最終更新日 | 2019-12-04 | | 実験手法 | X-RAY DIFFRACTION (1.954 Å) | | 主引用文献 | Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila.
Structure, 23, 2015
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5IPT
 | | Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 5 | | 分子名称: | Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a | | 著者 | Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E. | | 登録日 | 2016-03-09 | | 公開日 | 2016-04-20 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (14.1 Å) | | 主引用文献 | Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
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5IOU
 | | Cryo-EM structure of GluN1/GluN2B NMDA receptor in the glutamate/glycine-bound conformation | | 分子名称: | GLUTAMIC ACID, GLYCINE, Ionotropic glutamate receptor subunit NR2B, ... | | 著者 | Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E. | | 登録日 | 2016-03-09 | | 公開日 | 2016-04-20 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (7 Å) | | 主引用文献 | Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
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5IPU
 | | Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 6 | | 分子名称: | Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a | | 著者 | Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E. | | 登録日 | 2016-03-09 | | 公開日 | 2016-04-20 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (15.4 Å) | | 主引用文献 | Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
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5IPS
 | | Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 4 | | 分子名称: | Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a | | 著者 | Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E. | | 登録日 | 2016-03-09 | | 公開日 | 2016-04-20 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (13.5 Å) | | 主引用文献 | Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
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5IOV
 | | Cryo-EM structure of GluN1/GluN2B NMDA receptor in the glutamate/glycine/Ro25-6981-bound conformation | | 分子名称: | 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol, GLUTAMIC ACID, GLYCINE, ... | | 著者 | Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, Mchaourab, S.H, Gouaux, E. | | 登録日 | 2016-03-09 | | 公開日 | 2016-04-20 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (7.5 Å) | | 主引用文献 | Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
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5IPV
 | | Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 1 | | 分子名称: | Ionotropic glutamate receptor subunit NR2B, N-methyl-D-aspartate receptor subunit NR1-8a | | 著者 | Zhu, S, Stein, A.R, Yoshioka, C, Lee, C.H, Goehring, A, McHaourab, S.H, Gouaux, E. | | 登録日 | 2016-03-10 | | 公開日 | 2016-04-20 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (9.25 Å) | | 主引用文献 | Mechanism of NMDA Receptor Inhibition and Activation.
Cell, 165, 2016
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3GYG
 | | Crystal structure of yhjK (haloacid dehalogenase-like hydrolase protein) from Bacillus subtilis | | 分子名称: | MAGNESIUM ION, NTD biosynthesis operon putative hydrolase ntdB | | 著者 | Nocek, B, Stein, A, Wu, R, Jedrzejczak, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2009-04-03 | | 公開日 | 2009-05-12 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Crystal structure of yhjK (haloacid dehalogenase-like hydrolase protein) from Bacillus subtilis
To be Published
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5V7V
 | | Cryo-EM structure of ERAD-associated E3 ubiquitin-protein ligase component HRD3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ERAD-associated E3 ubiquitin-protein ligase component HRD3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Mi, W, Schoebel, S, Stein, A, Rapoport, T.A, Liao, M. | | 登録日 | 2017-03-20 | | 公開日 | 2017-08-16 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3.
Nature, 548, 2017
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5V6P
 | | CryoEM structure of the ERAD-associated E3 ubiquitin-protein ligase HRD1 | | 分子名称: | ERAD-associated E3 ubiquitin-protein ligase HRD1 | | 著者 | Schoebel, S, Mi, W, Stein, A, Rapoport, T.A, Liao, M. | | 登録日 | 2017-03-17 | | 公開日 | 2017-08-16 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3.
Nature, 548, 2017
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3RRL
 | | Complex structure of 3-oxoadipate coA-transferase subunit A and B from Helicobacter pylori 26695 | | 分子名称: | GLYCEROL, Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A, Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B | | 著者 | Nocek, B, Stein, A, Marshall, N, Jedrzejczak, R, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2011-04-29 | | 公開日 | 2011-06-29 | | 最終更新日 | 2012-01-11 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Complex structure of 3-oxoadipate coA-transferase subunit A and B
from Helicobacter pylori 26695
TO BE PUBLISHED
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3PFM
 | | Crystal structure of a EAL domain of GGDEF domain protein from Pseudomonas fluorescens Pf | | 分子名称: | GGDEF domain protein | | 著者 | Nocek, B, Stein, A, Marshall, N, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2010-10-28 | | 公開日 | 2010-11-10 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.908 Å) | | 主引用文献 | Crystal structure of a EAL domain of GGDEF domain protein from Pseudomonas fluorescens Pf
TO BE PUBLISHED
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3RPF
 | | Protein-protein complex of subunit 1 and 2 of Molybdopterin-converting factor from Helicobacter pylori 26695 | | 分子名称: | 1,2-ETHANEDIOL, Molybdopterin converting factor, subunit 1 (MoaD), ... | | 著者 | Nocek, B, Stein, A, Marshall, N, Jedrzejczak, R, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2011-04-26 | | 公開日 | 2011-06-29 | | 最終更新日 | 2012-01-11 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Protein-protein complex of subunit 1 and 2 of Molybdopterin-converting factor from Helicobacter pylori 26695
TO BE PUBLISHED
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3PAM
 | | Crystal structure of a domain of transmembrane protein of ABC-type oligopeptide transport system from Bartonella henselae str. Houston-1 | | 分子名称: | ETHANOL, Transmembrane protein | | 著者 | Nocek, B, Stein, A, Mack, J, Buck, K, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2010-10-19 | | 公開日 | 2010-11-17 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Crystal structure of a domain of transmembrane protein of ABC-type oligopeptide transport system from Bartonella henselae str. Houston-1"
TO BE PUBLISHED
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3PES
 | | Crystal structure of uncharacterized protein from Pseudomonas phage YuA | | 分子名称: | Uncharacterized protein gp49 | | 著者 | Nocek, B, Stein, A, Evdokimove, A, Egorova, O, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2010-10-27 | | 公開日 | 2010-12-08 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Crystal structure of uncharacterized protein from Pseudomonas phage YuA
TO BE PUBLISHED
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3PZJ
 | | Crystal structure of a probable acetyltransferases (GNAT family) from Chromobacterium violaceum ATCC 12472 | | 分子名称: | 1,2-ETHANEDIOL, Probable acetyltransferases, SODIUM ION | | 著者 | Nocek, B, Stein, A, Bigelow, L, Feldmann, B, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2010-12-14 | | 公開日 | 2011-01-19 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal structure of a probable acetyltransferases (GNAT family) from Chromobacterium violaceum ATCC 12472
TO BE PUBLISHED
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3OT6
 | | Crystal Structure of an enoyl-CoA hydratase/isomerase family protein from Psudomonas syringae | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Enoyl-CoA hydratase/isomerase family protein | | 著者 | Joachimiak, A, Duke, N.E.C, Stein, A, Chhor, G, Freeman, L, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2010-09-10 | | 公開日 | 2010-10-06 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structure of an enoyl-CoA hydratase/isomerase family protein from Psudomonas syringae
To be Published
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3QOC
 | | Crystal structure of N-terminal domain (Creatinase/Prolidase like domain) of putative metallopeptidase from Corynebacterium diphtheriae | | 分子名称: | CHLORIDE ION, Putative metallopeptidase, SULFATE ION | | 著者 | Nocek, B, Stein, A, Marshall, N, Putagunta, R, Feldmann, B, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2011-02-09 | | 公開日 | 2011-03-23 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Crystal structure of N-terminal domain (Creatinase/Prolidase like domain) of putative metallopeptidase from Corynebacterium diphtheriae
TO BE PUBLISHED
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3P9Z
 | | Crystal structure of uroporphyrinogen-III synthetase from Helicobacter pylori 26695 | | 分子名称: | MALONATE ION, Uroporphyrinogen III cosynthase (HemD) | | 著者 | Nocek, B, Stein, A, Chhor, G, Fenske, R.J, Buck, K, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2010-10-18 | | 公開日 | 2010-11-03 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of uroporphyrinogen-III synthetase from Helicobacter pylori 26695
To be Published
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3LM9
 | | Crystal structure of fructokinase with ADP and Fructose bound in the active site | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, SULFATE ION, ZINC ION, ... | | 著者 | Nocek, B, Stein, A, Cuff, M, Volkart, L, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2010-01-29 | | 公開日 | 2010-03-09 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structural studies of ROK fructokinase YdhR from Bacillus subtilis: insights into substrate binding and fructose specificity.
J.Mol.Biol., 406, 2011
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