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PDB: 71 件
2GWL
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Crystal structure of the Salmonella SpvB ATR Domain in complex with NADH
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 65 kDa virulence protein
著者Stebbins, C.E, Margarit, S.M.
登録日2006-05-04
公開日2006-08-29
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A steric antagonism of actin polymerization by a salmonella virulence protein.
Structure, 14, 2006
2GWM
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Crystal structure of the Salmonella SpvB ATR Domain
分子名称: 65 kDa virulence protein, SULFATE ION
著者Stebbins, C.E, Margarit, S.M.
登録日2006-05-04
公開日2006-08-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A steric antagonism of actin polymerization by a salmonella virulence protein.
Structure, 14, 2006
3BEO
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A Structural Basis for the allosteric regulation of non-hydrolyzing UDP-GlcNAc 2-epimerases
分子名称: UDP-N-acetylglucosamine 2-epimerase, URIDINE-5'-DIPHOSPHATE, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
著者Velloso, L.M, Bhaskaran, S.S, Schuch, R, Fischetti, V.A, Stebbins, C.E.
登録日2007-11-19
公開日2008-02-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A structural basis for the allosteric regulation of non-hydrolysing UDP-GlcNAc 2-epimerases.
Embo Rep., 9, 2008
4YX5
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SpaO(SPOA1,2)
分子名称: CHLORIDE ION, Surface presentation of antigens protein SpaO
著者Notti, R.Q, Stebbins, C.E.
登録日2015-03-22
公開日2015-06-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.9001 Å)
主引用文献A common assembly module in injectisome and flagellar type III secretion sorting platforms.
Nat Commun, 6, 2015
4MI7
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Crystal Structure of Salmonella Effector Protein GtgE
分子名称: Bacteriophage encoded virulence factor, SULFATE ION
著者Kohler, A.C, Stebbins, C.E.
登録日2013-08-30
公開日2014-02-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural and enzymatic characterization of a host-specificity determinant from Salmonella.
Acta Crystallogr.,Sect.D, 70, 2014
2P2L
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Rac1-GDP-Zinc Complex
分子名称: GUANOSINE-5'-DIPHOSPHATE, Ras-related C3 botulinum toxin substrate 1, ZINC ION
著者Prehna, G, Stebbins, C.E.
登録日2007-03-07
公開日2007-05-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A Rac1-GDP trimer complex binds zinc with tetrahedral and octahedral coordination, displacing magnesium.
Acta Crystallogr.,Sect.D, 63, 2007
8B3W
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Structure of metacyclic VSG (mVSG) 1954 from Trypanosoma brucei
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BROMIDE ION, Variant surface glycoprotein 1954
著者Chandra, M, Stebbins, C.E.
登録日2022-09-17
公開日2023-01-25
最終更新日2023-04-19
実験手法X-RAY DIFFRACTION (1.681 Å)
主引用文献Structural similarities between the metacyclic and bloodstream form variant surface glycoproteins of the African trypanosome.
Plos Negl Trop Dis, 17, 2023
8B3B
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Structure of metacyclic VSG (mVSG) 531 from Trypanosoma brucei
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Variant surface glycoprotein 531, alpha-D-mannopyranose, ...
著者Chandra, M, Stebbins, C.E.
登録日2022-09-16
公開日2023-01-25
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.949 Å)
主引用文献Structural similarities between the metacyclic and bloodstream form variant surface glycoproteins of the African trypanosome.
Plos Negl Trop Dis, 17, 2023
8B3E
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Variant Surface Glycoprotein VSG397
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Variant surface glycoprotein 397
著者Zeelen, J.P, Stebbins, C.E, Dakovic, S, Foti, K.
登録日2022-09-16
公開日2023-01-25
最終更新日2023-04-19
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Structural similarities between the metacyclic and bloodstream form variant surface glycoproteins of the African trypanosome.
Plos Negl Trop Dis, 17, 2023
3G06
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The Salmonella Virulence Effector SspH2 Functions As A Novel E3 Ligase
分子名称: SspH2 (Leucine-rich repeat protein)
著者Quezada, C.M, Stebbins, C.E.
登録日2009-01-27
公開日2009-04-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A family of Salmonella virulence factors functions as a distinct class of autoregulated E3 ubiquitin ligases.
Proc.Natl.Acad.Sci.USA, 106, 2009
7QT2
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Antibody FenAb208 - fentanyl complex
分子名称: Antibody heavy chain, Antibody light chain, N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide
著者Zeelen, J.P, Straaten van, M, Stebbins, C.E.
登録日2022-01-14
公開日2023-05-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献A trypanosome-derived immunotherapeutics platform elicits potent high-affinity antibodies, negating the effects of the synthetic opioid fentanyl.
Cell Rep, 42, 2023
7QT0
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Antibody FenAb136 - fentanyl complex
分子名称: 2-[2-[2-[2-[[5-oxidanylidene-5-[2-[4-[phenyl(propanoyl)amino]piperidin-1-yl]ethylamino]pentanoyl]amino]ethanoylamino]ethanoylamino]ethanoylamino]ethanoic acid, Antibody heavy chain, Antibody light chain
著者Zeelen, J.P, Straaten van, M, Stebbins, C.E.
登録日2022-01-14
公開日2023-05-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献A trypanosome-derived immunotherapeutics platform elicits potent high-affinity antibodies, negating the effects of the synthetic opioid fentanyl.
Cell Rep, 42, 2023
7QT4
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Antibody FenAb709 - fentanyl complex
分子名称: 2-[2-[2-[2-[[5-oxidanylidene-5-[2-[4-[phenyl(propanoyl)amino]piperidin-1-yl]ethylamino]pentanoyl]amino]ethanoylamino]ethanoylamino]ethanoylamino]ethanoic acid, Antibody heavy chain, Antibody light chain
著者Zeelen, J.P, Straaten van, M, Stebbins, C.E.
登録日2022-01-14
公開日2023-05-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献A trypanosome-derived immunotherapeutics platform elicits potent high-affinity antibodies, negating the effects of the synthetic opioid fentanyl.
Cell Rep, 42, 2023
7QT3
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Antibody FenAb609 - fentanyl complex
分子名称: Antibody heavy chain, Antibody light chain, N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide
著者Zeelen, J.P, Straaten van, M, Stebbins, C.E.
登録日2022-01-14
公開日2023-05-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A trypanosome-derived immunotherapeutics platform elicits potent high-affinity antibodies, negating the effects of the synthetic opioid fentanyl.
Cell Rep, 42, 2023
1SR4
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Crystal Structure of the Haemophilus ducreyi cytolethal distending toxin
分子名称: BROMIDE ION, Cytolethal distending toxin subunit A, cytolethal distending toxin protein B, ...
著者Nesic, D, Hsu, Y, Stebbins, C.E.
登録日2004-03-22
公開日2004-06-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Assembly and Function of a Bacterial Genotoxin
Nature, 429, 2004
1GRJ
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GREA TRANSCRIPT CLEAVAGE FACTOR FROM ESCHERICHIA COLI
分子名称: GREA PROTEIN
著者Darst, S.A, Stebbins, C.E.
登録日1995-05-02
公開日1995-07-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the GreA transcript cleavage factor from Escherichia coli.
Nature, 373, 1995
8OK4
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Variant Surface Glycoprotein VSG11wt-Oil
分子名称: Variant surface glycoprotein, alpha-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Zeelen, J.P, Stebbins, C.E, Aresta-Branco, F, Foti, K.
登録日2023-03-27
公開日2023-09-13
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献A structural classification of the variant surface glycoproteins of the African trypanosomey.
Plos Negl Trop Dis, 17, 2023
8ONH
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Variant Surface Glycoprotein VSG11wt-Oil
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Variant surface glycoprotein, alpha-D-glucopyranose, ...
著者Zeelen, J.P, Stebbins, C.E, Foti, K, Gkeka, A, Vlachou, E.P.
登録日2023-04-03
公開日2023-09-13
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献A structural classification of the variant surface glycoproteins of the African trypanosomey.
Plos Negl Trop Dis, 17, 2023
8OK8
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Variant Surface Glycoprotein VSG615
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Variant surface glycoprotein 615, ...
著者Zeelen, J.P, Stebbins, C.E, Chandra, M.
登録日2023-03-27
公開日2023-09-13
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献A structural classification of the variant surface glycoproteins of the African trypanosomey.
Plos Negl Trop Dis, 17, 2023
8OK5
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Variant Surface Glycoprotein VSG11 monomer with iodine
分子名称: IODIDE ION, Variant surface glycoprotein, alpha-D-glucopyranose, ...
著者Zeelen, J.P, Stebbins, C.E, Aresta-Branco, F.
登録日2023-03-27
公開日2023-09-13
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献A structural classification of the variant surface glycoproteins of the African trypanosomey.
Plos Negl Trop Dis, 17, 2023
8OK6
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Variant Surface Glycoprotein VSG11 two monomers
分子名称: SULFATE ION, Variant surface glycoprotein, alpha-D-glucopyranose, ...
著者Gkeka, A, Vlachou, E.P, Zeelen, J.P, Stebbins, C.E.
登録日2023-03-27
公開日2023-09-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A structural classification of the variant surface glycoproteins of the African trypanosomey.
Plos Negl Trop Dis, 17, 2023
8OK7
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Variant Surface Glycoprotein VSG558 NTD
分子名称: Variant surface glycoprotein 558, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zeelen, J.P, Stebbins, C.E, van Straaten, M, Zhong, J.
登録日2023-03-27
公開日2023-09-13
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献A structural classification of the variant surface glycoproteins of the African trypanosomey.
Plos Negl Trop Dis, 17, 2023
7P56
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Variant Surface Glycoprotein 2 (VSG2, MiTat1.2, VSG221) Bound to Calcium
分子名称: CALCIUM ION, Variant surface glycoprotein MITAT 1.2, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Gkeka, A, Aresta-Branco, F, Stebbins, C.E, Papavasiliou, F.N.
登録日2021-07-14
公開日2022-07-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.735 Å)
主引用文献Immunodominant surface epitopes power immune evasion in the African trypanosome.
Cell Rep, 42, 2023
7P5D
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Variant Surface Glycoprotein 3 (VSG3, MiTat1.3, VSG224) mutant (serine 317 and 319 to alanine)
分子名称: Variant surface glycoprotein, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Gkeka, A, Aresta-Branco, F, Stebbins, C.E, Papavasiliou, F.N.
登録日2021-07-14
公開日2022-07-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Immunodominant surface epitopes power immune evasion in the African trypanosome.
Cell Rep, 42, 2023
7P57
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VSG2 mutant structure lacking the calcium binding pocket
分子名称: Variant surface glycoprotein MITAT 1.2, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Gkeka, A, Aresta-Branco, F, Stebbins, C.E, Papavasiliou, F.N.
登録日2021-07-14
公開日2022-07-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.961 Å)
主引用文献Immunodominant surface epitopes power immune evasion in the African trypanosome.
Cell Rep, 42, 2023

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