6M87
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![BU of 6m87 by Molmil](/molmil-images/mine/6m87) | Fab 10A6 in complex with MPTS | Descriptor: | 8-methoxypyrene-1,3,6-trisulfonic acid, Fab 10A6 heavy chain, Fab 10A6 light chain, ... | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2018-08-21 | Release date: | 2019-07-03 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.609 Å) | Cite: | Structure and Dynamics of Stacking Interactions in an Antibody Binding Site. Biochemistry, 58, 2019
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4RBP
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![BU of 4rbp by Molmil](/molmil-images/mine/4rbp) | Crystal structure of HIV neutralizing antibody 2G12 in complex with a bacterial oligosaccharide analog of mammalian oligomanose | Descriptor: | Fab 2G12 heavy chain, Fab 2G12 light chain, GLYCEROL, ... | Authors: | Stanfield, R.L, Wilson, I.A, De Castro, C, Marzaioli, A.M, Pantophlet, R. | Deposit date: | 2014-09-12 | Release date: | 2014-11-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of the HIV neutralizing antibody 2G12 in complex with a bacterial oligosaccharide analog of mammalian oligomannose. Glycobiology, 25, 2015
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6OPA
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![BU of 6opa by Molmil](/molmil-images/mine/6opa) | |
8GJV
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![BU of 8gjv by Molmil](/molmil-images/mine/8gjv) | |
3OZ9
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![BU of 3oz9 by Molmil](/molmil-images/mine/3oz9) | |
3Q1S
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![BU of 3q1s by Molmil](/molmil-images/mine/3q1s) | HIV-1 neutralizing antibody Z13e1 in complex with epitope display protein | Descriptor: | GLYCEROL, ISOPROPYL ALCOHOL, Interleukin-22, ... | Authors: | Stanfield, R.L, Julien, J.-P, Pejchal, R, Gach, J.S, Zwick, M.B, Wilson, I.A. | Deposit date: | 2010-12-17 | Release date: | 2011-11-02 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structure-Based Design of a Protein Immunogen that Displays an HIV-1 gp41 Neutralizing Epitope. J.Mol.Biol., 414, 2011
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2IGF
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![BU of 2igf by Molmil](/molmil-images/mine/2igf) | |
5J75
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![BU of 5j75 by Molmil](/molmil-images/mine/5j75) | Fluorogen Activating Protein AM2.2 in complex with ML342 | Descriptor: | N,4-dimethyl-N-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethyl}benzene-1-sulfonamide, PHOSPHATE ION, scFv AM2.2 | Authors: | Stanfield, R.L, Wilson, I.A, Wu, Y. | Deposit date: | 2016-04-05 | Release date: | 2016-05-04 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery of Small-Molecule Nonfluorescent Inhibitors of Fluorogen-Fluorogen Activating Protein Binding Pair. J Biomol Screen, 21, 2016
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5J74
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![BU of 5j74 by Molmil](/molmil-images/mine/5j74) | Fluorogen activating protein AM2.2 in complex with TO1-2p | Descriptor: | 1-(17-amino-5,8-dioxo-12,15-dioxa-4,9-diazaheptadecan-1-yl)-4-{[3-(3-sulfopropyl)-1,3-benzothiazol-3-ium-2-yl]methyl}quinolin-1-ium, PHOSPHATE ION, scFv AM2.2 | Authors: | Stanfield, R.L, Wilson, I.A, Wu, Y. | Deposit date: | 2016-04-05 | Release date: | 2016-05-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Discovery of Small-Molecule Nonfluorescent Inhibitors of Fluorogen-Fluorogen Activating Protein Binding Pair. J Biomol Screen, 21, 2016
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1F58
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![BU of 1f58 by Molmil](/molmil-images/mine/1f58) | IGG1 FAB FRAGMENT (58.2) COMPLEX WITH 24-RESIDUE PEPTIDE (RESIDUES 308-333 OF HIV-1 GP120 (MN ISOLATE) WITH ALA TO AIB SUBSTITUTION AT POSITION 323 | Descriptor: | Envelope glycoprotein gp120, PROTEIN (IGG1 ANTIBODY 58.2 (HEAVY CHAIN)), PROTEIN (IGG1 ANTIBODY 58.2 (LIGHT CHAIN)) | Authors: | Stanfield, R.L, Cabezas, E, Satterthwait, A.C, Stura, E.A, Profy, A.T, Wilson, I.A. | Deposit date: | 1998-10-21 | Release date: | 1999-02-02 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs. Structure Fold.Des., 7, 1999
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3F58
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![BU of 3f58 by Molmil](/molmil-images/mine/3f58) | IGG1 FAB FRAGMENT (58.2) COMPLEX WITH 12-RESIDUE CYCLIC PEPTIDE (INCLUDING RESIDUES 315-324 OF HIV-1 GP120 (MN ISOLATE); H315S MUTATION | Descriptor: | PROTEIN (CYCLIC PEPTIDE (GP120)), PROTEIN (IMMUNOGLOBULIN GAMMA I (58.2)) | Authors: | Stanfield, R.L, Cabezas, E, Satterthwait, A.C, Stura, E.A, Profy, A.T, Wilson, I.A. | Deposit date: | 1998-10-23 | Release date: | 1999-02-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs. Structure Fold.Des., 7, 1999
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5ILT
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![BU of 5ilt by Molmil](/molmil-images/mine/5ilt) | Crystal structure of bovine Fab A01 | Descriptor: | bovine Fab A01 heavy chain, bovine Fab A01 light chain | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2016-03-04 | Release date: | 2016-08-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies. Sci Immunol, 1, 2016
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5IJV
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![BU of 5ijv by Molmil](/molmil-images/mine/5ijv) | Crystal structure of bovine Fab E03 | Descriptor: | bovine Fab E03 heavy chain, bovine Fab E03 light chain | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2016-03-02 | Release date: | 2016-10-05 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies. Sci Immunol, 1, 2016
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5T3S
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![BU of 5t3s by Molmil](/molmil-images/mine/5t3s) | HIV gp140 trimer MD39-10MUTA in complex with Fabs PGT124 and 35022 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | Authors: | Stanfield, R.L, Wilson, I.A. | Deposit date: | 2016-08-26 | Release date: | 2016-09-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies. Immunity, 45, 2016
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2I27
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![BU of 2i27 by Molmil](/molmil-images/mine/2i27) | |
2I25
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![BU of 2i25 by Molmil](/molmil-images/mine/2i25) | |
2I24
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![BU of 2i24 by Molmil](/molmil-images/mine/2i24) | |
2I26
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![BU of 2i26 by Molmil](/molmil-images/mine/2i26) | |
1SQ2
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![BU of 1sq2 by Molmil](/molmil-images/mine/1sq2) | Crystal Structure Analysis of the Nurse Shark New Antigen Receptor (NAR) Variable Domain in Complex With Lysozyme | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C, ... | Authors: | Stanfield, R.L, Dooley, H, Flajnik, M.F, Wilson, I.A. | Deposit date: | 2004-03-17 | Release date: | 2004-08-24 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Crystal structure of a shark single-domain antibody V region in complex with lysozyme. Science, 305, 2004
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1Q1J
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![BU of 1q1j by Molmil](/molmil-images/mine/1q1j) | Crystal Structure Analysis of anti-HIV-1 Fab 447-52D in complex with V3 peptide | Descriptor: | Fab 447-52D, heavy chain, light chain, ... | Authors: | Stanfield, R.L, Gorny, M.K, Williams, C, Zolla-Pazner, S, Wilson, I.A. | Deposit date: | 2003-07-21 | Release date: | 2004-02-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural rationale for the broad neutralization of HIV-1 by human monoclonal antibody 447-52D. Structure, 12, 2004
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1T6V
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![BU of 1t6v by Molmil](/molmil-images/mine/1t6v) | Crystal structure analysis of the nurse shark new antigen receptor (NAR) variable domain in complex with lysozyme | Descriptor: | CHLORIDE ION, Lysozyme C, novel antigen receptor | Authors: | Stanfield, R.L, Dooley, H, Flajnik, M.F, Wilson, I.A. | Deposit date: | 2004-05-07 | Release date: | 2004-08-24 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of a shark single-domain antibody V region in complex with lysozyme. Science, 305, 2004
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2OJZ
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![BU of 2ojz by Molmil](/molmil-images/mine/2ojz) | Anti-DNA antibody ED10 | Descriptor: | Fab ED10 heavy chain, Fab ED10 light chain | Authors: | Stanfield, R.L, Sanguineti, S, Wilson, I.A, de Prat-Gay, G. | Deposit date: | 2007-01-15 | Release date: | 2007-06-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | Specific recognition of a DNA immunogen by its elicited antibody J.Mol.Biol., 370, 2007
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2OK0
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![BU of 2ok0 by Molmil](/molmil-images/mine/2ok0) | Fab ED10-DNA complex | Descriptor: | 5'-D(*TP*C)-3', Fab ED10 heavy chain, Fab ED10 light chain | Authors: | Stanfield, R.L, Sanguineti, S, Wilson, I.A, de Prat-Gay, G. | Deposit date: | 2007-01-15 | Release date: | 2007-06-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Specific recognition of a DNA immunogen by its elicited antibody J.Mol.Biol., 370, 2007
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2B1H
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![BU of 2b1h by Molmil](/molmil-images/mine/2b1h) | Crystal structure analysis of anti-HIV-1 V3 Fab 2219 in complex with UG29 peptide | Descriptor: | Fab 2219, heavy chain, light chain, ... | Authors: | Stanfield, R.L, Gorny, M.K, Zolla-Pazner, S, Wilson, I.A. | Deposit date: | 2005-09-15 | Release date: | 2006-07-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity. J.Virol., 80, 2006
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2B0S
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![BU of 2b0s by Molmil](/molmil-images/mine/2b0s) | Crystal structure analysis of anti-HIV-1 V3 Fab 2219 in complex with MN peptide | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, Fab 2219, ... | Authors: | Stanfield, R.L, Gorny, M.K, Zolla-Pazner, S, Wilson, I.A. | Deposit date: | 2005-09-14 | Release date: | 2006-07-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity. J.Virol., 80, 2006
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