3OZ9
 
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2I24
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2B1H
 | | Crystal structure analysis of anti-HIV-1 V3 Fab 2219 in complex with UG29 peptide | | Descriptor: | Fab 2219, heavy chain, light chain, ... | | Authors: | Stanfield, R.L, Gorny, M.K, Zolla-Pazner, S, Wilson, I.A. | | Deposit date: | 2005-09-15 | | Release date: | 2006-07-04 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity.
J.Virol., 80, 2006
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2I26
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2I27
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2B1A
 | | Crystal structure analysis of anti-HIV-1 V3 Fab 2219 in complex with UG1033 peptide | | Descriptor: | Fab 2219, heavy chain, light chain, ... | | Authors: | Stanfield, R.L, Gorny, M.K, Zolla-Pazner, S, Wilson, I.A. | | Deposit date: | 2005-09-15 | | Release date: | 2006-07-04 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.348 Å) | | Cite: | Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity.
J.Virol., 80, 2006
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6CXL
 | | anti-HIV-1 Fab 2G12 in complex with glycopeptide 10F5 | | Descriptor: | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose, anti-HIV-1 Fab 2G12 heavy chain, anti-HIV-1 Fab 2G12 light chain | | Authors: | Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2018-04-03 | | Release date: | 2019-02-20 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3.586 Å) | | Cite: | Oligomannose Glycopeptide Conjugates Elicit Antibodies Targeting the Glycan Core Rather than Its Extremities.
ACS Cent Sci, 5, 2019
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6CXG
 | | anti-HIV-1 Fab 2G12 in complex with glycopeptide 10V1S | | Descriptor: | 10V1S glycopeptide, GLYCEROL, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose, ... | | Authors: | Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2018-04-03 | | Release date: | 2019-02-20 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.298 Å) | | Cite: | Oligomannose Glycopeptide Conjugates Elicit Antibodies Targeting the Glycan Core Rather than Its Extremities.
ACS Cent Sci, 5, 2019
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2I25
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2B0S
 | | Crystal structure analysis of anti-HIV-1 V3 Fab 2219 in complex with MN peptide | | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, Fab 2219, ... | | Authors: | Stanfield, R.L, Gorny, M.K, Zolla-Pazner, S, Wilson, I.A. | | Deposit date: | 2005-09-14 | | Release date: | 2006-07-04 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity.
J.Virol., 80, 2006
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3Q1S
 | | HIV-1 neutralizing antibody Z13e1 in complex with epitope display protein | | Descriptor: | GLYCEROL, ISOPROPYL ALCOHOL, Interleukin-22, ... | | Authors: | Stanfield, R.L, Julien, J.-P, Pejchal, R, Gach, J.S, Zwick, M.B, Wilson, I.A. | | Deposit date: | 2010-12-17 | | Release date: | 2011-11-02 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structure-Based Design of a Protein Immunogen that Displays an HIV-1 gp41 Neutralizing Epitope.
J.Mol.Biol., 414, 2011
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2F58
 | | IGG1 FAB FRAGMENT (58.2) COMPLEX WITH 12-RESIDUE CYCLIC PEPTIDE (INCLUDING RESIDUES 315-324 OF HIV-1 GP120) (MN ISOLATE) | | Descriptor: | 1-IMINO-5-PENTANONE, PROTEIN (HIV-1 GP120), PROTEIN (IGG1 FAB 58.2 ANTIBODY (HEAVY CHAIN)), ... | | Authors: | Stanfield, R.L, Cabezas, E, Satterthwait, A.C, Stura, E.A, Profy, A.T, Wilson, I.A. | | Deposit date: | 1998-10-23 | | Release date: | 1999-02-09 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs.
Structure Fold.Des., 7, 1999
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5ILT
 | | Crystal structure of bovine Fab A01 | | Descriptor: | bovine Fab A01 heavy chain, bovine Fab A01 light chain | | Authors: | Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2016-03-04 | | Release date: | 2016-08-24 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies.
Sci Immunol, 1, 2016
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5IJV
 | | Crystal structure of bovine Fab E03 | | Descriptor: | bovine Fab E03 heavy chain, bovine Fab E03 light chain | | Authors: | Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2016-03-02 | | Release date: | 2016-10-05 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies.
Sci Immunol, 1, 2016
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3T0W
 | | Fluorogen activating protein M8VL in complex with dimethylindole red | | Descriptor: | 1-(3-sulfopropyl)-4-[(1E,3E)-3-(1,3,3-trimethyl-1,3-dihydro-2H-indol-2-ylidene)prop-1-en-1-yl]quinolinium, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, CHLORIDE ION, ... | | Authors: | Stanfield, R, Senutovitch, N, Bhattacharyya, S, Rule, G, Wilson, I.A, Armitage, B, Waggoner, A.S, Berget, P. | | Deposit date: | 2011-07-20 | | Release date: | 2012-03-21 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (1.501 Å) | | Cite: | A variable light domain fluorogen activating protein homodimerizes to activate dimethylindole red.
Biochemistry, 51, 2012
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3T0X
 | | Fluorogen Activating Protein M8VLA4(S55P) in complex with dimethylindole red | | Descriptor: | 1,2-ETHANEDIOL, 1-(3-sulfopropyl)-4-[(1E,3E)-3-(1,3,3-trimethyl-1,3-dihydro-2H-indol-2-ylidene)prop-1-en-1-yl]quinolinium, Immunoglobulin variable lambda domain M8VLA4(S55P), ... | | Authors: | Stanfield, R, Senutovitch, N, Bhattacharyya, S, Rule, G, Wilson, I.A, Armitage, B, Waggoner, A.S, Berget, P. | | Deposit date: | 2011-07-20 | | Release date: | 2012-03-21 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (1.96 Å) | | Cite: | A variable light domain fluorogen activating protein homodimerizes to activate dimethylindole red.
Biochemistry, 51, 2012
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3T0V
 | | Unliganded fluorogen activating protein M8VL | | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, ... | | Authors: | Stanfield, R, Senutovitch, N, Bhattacharyya, S, Rule, G, Wilson, I.A, Armitage, B, Waggoner, A.S, Berget, P. | | Deposit date: | 2011-07-20 | | Release date: | 2012-03-21 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (1.451 Å) | | Cite: | A variable light domain fluorogen activating protein homodimerizes to activate dimethylindole red.
Biochemistry, 51, 2012
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6M87
 | | Fab 10A6 in complex with MPTS | | Descriptor: | 8-methoxypyrene-1,3,6-trisulfonic acid, Fab 10A6 heavy chain, Fab 10A6 light chain, ... | | Authors: | Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2018-08-21 | | Release date: | 2019-07-03 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.609 Å) | | Cite: | Structure and Dynamics of Stacking Interactions in an Antibody Binding Site.
Biochemistry, 58, 2019
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5T3S
 | | HIV gp140 trimer MD39-10MUTA in complex with Fabs PGT124 and 35022 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... | | Authors: | Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2016-08-26 | | Release date: | 2016-09-28 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (4.5 Å) | | Cite: | HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies.
Immunity, 45, 2016
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5U65
 | | Camel Nanobody VHH-5 | | Descriptor: | SULFATE ION, VHH-5 | | Authors: | Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2016-12-07 | | Release date: | 2017-09-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Selection of nanobodies with broad neutralizing potential against primary HIV-1 strains using soluble subtype C gp140 envelope trimers.
Sci Rep, 7, 2017
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4NJ9
 | | Crystal structure of Fab 8B10 in complex with MPTS | | Descriptor: | 8-methoxypyrene-1,3,6-trisulfonic acid, 8B10 heavy chain, 8B10 light chain, ... | | Authors: | Stanfield, R.L, Romesberg, F.E, Zimmermann, J, Wilson, I.A. | | Deposit date: | 2013-11-08 | | Release date: | 2014-11-12 | | Last modified: | 2017-06-14 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Adaptive Mutations Alter Antibody Structure and Dynamics during Affinity Maturation.
Biochemistry, 54, 2015
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4NJA
 | | Crystal structure of Fab 6C8 in complex with MPTS | | Descriptor: | 6C8 heavy chain, 6C8 light chain, 8-methoxypyrene-1,3,6-trisulfonic acid, ... | | Authors: | Stanfield, R.L, Romesberg, F.E, Zimmermann, J, Wilson, I.A. | | Deposit date: | 2013-11-08 | | Release date: | 2014-11-12 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.204 Å) | | Cite: | Adaptive Mutations Alter Antibody Structure and Dynamics during Affinity Maturation.
Biochemistry, 54, 2015
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5U64
 | | Camel nanobody VHH-28 | | Descriptor: | VHH-28 | | Authors: | Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2016-12-07 | | Release date: | 2017-09-20 | | Method: | X-RAY DIFFRACTION (1.153 Å) | | Cite: | Selection of nanobodies with broad neutralizing potential against primary HIV-1 strains using soluble subtype C gp140 envelope trimers.
Sci Rep, 7, 2017
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4M61
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4K3H
 | | Immunoglobulin lambda variable domain L5(L89S) fluorogen activationg protein in complex with malachite green | | Descriptor: | 4-{bis[4-(dimethylamino)phenyl]methyl}phenol, GLYCEROL, Immunoglobulin lambda variable domain L5(L89S), ... | | Authors: | Stanfield, R.L, Szent-Gyorgyi, C, Wilson, I.A. | | Deposit date: | 2013-04-10 | | Release date: | 2013-10-09 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Malachite Green Mediates Homodimerization of Antibody VL Domains to Form a Fluorescent Ternary Complex with Singular Symmetric Interfaces.
J.Mol.Biol., 425, 2013
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