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PDB: 98 件
5VIJ
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Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-bromophenyl-ACEPC
分子名称: 5-[(2R)-2-amino-2-carboxyethyl]-1-(4-bromophenyl)-1H-pyrazole-3-carboxylic acid, GLYCINE, Glutamate receptor ionotropic, ...
著者Mou, T.-C, Conti, P, Pinto, A, Tamborini, L, Sprang, S.R, Hansen, K.B.
登録日2017-04-16
公開日2017-04-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.105 Å)
主引用文献Structural basis of subunit selectivity for competitive NMDA receptor antagonists with preference for GluN2A over GluN2B subunits.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5TY3
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BU of 5ty3 by Molmil
Crystal structure of K72A variant of Human Cytochrome c
分子名称: Cytochrome c, HEME C, SULFATE ION
著者Mou, T.C, Nold, S.M, Lei, H, Sprang, S.R, Bowler, B.E.
登録日2016-11-18
公開日2017-09-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Effect of a K72A Mutation on the Structure, Stability, Dynamics, and Peroxidase Activity of Human Cytochrome c.
Biochemistry, 56, 2017
1GG2
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G PROTEIN HETEROTRIMER MUTANT GI_ALPHA_1(G203A) BETA_1 GAMMA_2 WITH GDP BOUND
分子名称: G PROTEIN GI ALPHA 1, G PROTEIN GI BETA 1, G PROTEIN GI GAMMA 2, ...
著者Wall, M.A, Sprang, S.R.
登録日1996-11-13
公開日1997-02-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2.
Cell(Cambridge,Mass.), 83, 1995
1EXT
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BU of 1ext by Molmil
EXTRACELLULAR DOMAIN OF THE 55KDA TUMOR NECROSIS FACTOR RECEPTOR. CRYSTALLIZED AT PH3.7 IN P 21 21 21.
分子名称: MAGNESIUM ION, SULFATE ION, TUMOR NECROSIS FACTOR RECEPTOR
著者Naismith, J.H, Sprang, S.R.
登録日1996-07-03
公開日1997-01-11
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structures of the extracellular domain of the type I tumor necrosis factor receptor.
Structure, 4, 1996
1IK7
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BU of 1ik7 by Molmil
Crystal Structure of the Uncomplexed Pelle Death Domain
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PROBABLE SERINE/THREONINE-PROTEIN KINASE Pelle
著者Xiao, T, Gardner, K.H, Sprang, S.R.
登録日2001-05-02
公開日2002-07-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Cosolvent-induced transformation of a death domain tertiary structure
Proc.Natl.Acad.Sci.USA, 99, 2002
1CJV
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COMPLEX OF GS-ALPHA WITH THE CATALYTIC DOMAINS OF MAMMALIAN ADENYLYL CYCLASE: COMPLEX WITH BETA-L-2',3'-DIDEOXYATP, MG, AND ZN
分子名称: 2',3'-DIDEOXYADENOSINE-5'-TRIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ...
著者Tesmer, J.J.G, Sprang, S.R.
登録日1999-04-19
公開日1999-08-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Two-metal-Ion catalysis in adenylyl cyclase.
Science, 285, 1999
1CS4
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COMPLEX OF GS-ALPHA WITH THE CATALYTIC DOMAINS OF MAMMALIAN ADENYLYL CYCLASE: COMPLEX WITH 2'-DEOXY-ADENOSINE 3'-MONOPHOSPHATE, PYROPHOSPHATE AND MG
分子名称: 2'-DEOXY-ADENOSINE 3'-MONOPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ...
著者Tesmer, J.J.G, Dessauer, C.A, Sunahara, R.K, Johnson, R.A, Gilman, A.G, Sprang, S.R.
登録日1999-08-16
公開日2001-01-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular basis for P-site inhibition of adenylyl cyclase.
Biochemistry, 39, 2000
1CJK
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COMPLEX OF GS-ALPHA WITH THE CATALYTIC DOMAINS OF MAMMALIAN ADENYLYL CYCLASE: COMPLEX WITH ADENOSINE 5'-(ALPHA THIO)-TRIPHOSPHATE (RP), MG, AND MN
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ADENOSINE-5'-RP-ALPHA-THIO-TRIPHOSPHATE, ...
著者Tesmer, J.J.G, Sprang, S.R.
登録日1999-04-16
公開日1999-08-31
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Two-metal-Ion catalysis in adenylyl cyclase.
Science, 285, 1999
1CJT
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COMPLEX OF GS-ALPHA WITH THE CATALYTIC DOMAINS OF MAMMALIAN ADENYLYL CYCLASE: COMPLEX WITH BETA-L-2',3'-DIDEOXYATP, MN, AND MG
分子名称: 2',3'-DIDEOXYADENOSINE-5'-TRIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ...
著者Tesmer, J.J.G, Sprang, S.R.
登録日1999-04-16
公開日1999-08-31
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Two-metal-Ion catalysis in adenylyl cyclase.
Science, 285, 1999
1CJU
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COMPLEX OF GS-ALPHA WITH THE CATALYTIC DOMAINS OF MAMMALIAN ADENYLYL CYCLASE: COMPLEX WITH BETA-L-2',3'-DIDEOXYATP AND MG
分子名称: 2',3'-DIDEOXYADENOSINE-5'-TRIPHOSPHATE, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ADENYLATE CYCLASE, ...
著者Tesmer, J.J.G, Sprang, S.R.
登録日1999-04-16
公開日1999-08-31
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Two-metal-Ion catalysis in adenylyl cyclase.
Science, 285, 1999
1CIP
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BU of 1cip by Molmil
GI-ALPHA-1 SUBUNIT OF GUANINE NUCLEOTIDE-BINDING PROTEIN COMPLEXED WITH A GTP ANALOGUE
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, PROTEIN (GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-1 SUBUNIT)
著者Coleman, D, Sprang, S.
登録日1999-04-05
公開日1999-04-09
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of Gialpha1.GppNHp, autoinhibition in a galpha protein-substrate complex.
J.Biol.Chem., 274, 1999
1AS0
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BU of 1as0 by Molmil
GTP-GAMMA-S BOUND G42V GIA1
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GIA1, MAGNESIUM ION, ...
著者Raw, A.S, Coleman, D.E, Gilman, A.G, Sprang, S.R.
登録日1997-08-11
公開日1997-11-12
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and biochemical characterization of the GTPgammaS-, GDP.Pi-, and GDP-bound forms of a GTPase-deficient Gly42 --> Val mutant of Gialpha1.
Biochemistry, 36, 1997
1AS3
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BU of 1as3 by Molmil
GDP BOUND G42V GIA1
分子名称: GIA1, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION
著者Raw, A.S, Coleman, D.E, Gilman, A.G, Sprang, S.R.
登録日1997-08-11
公開日1997-11-12
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and biochemical characterization of the GTPgammaS-, GDP.Pi-, and GDP-bound forms of a GTPase-deficient Gly42 --> Val mutant of Gialpha1.
Biochemistry, 36, 1997
1AS2
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GDP+PI BOUND G42V GIA1
分子名称: GIA1, GUANOSINE-5'-DIPHOSPHATE, PHOSPHATE ION
著者Raw, A.S, Coleman, D.E, Gilman, A.G, Sprang, S.R.
登録日1997-08-11
公開日1997-11-12
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and biochemical characterization of the GTPgammaS-, GDP.Pi-, and GDP-bound forms of a GTPase-deficient Gly42 --> Val mutant of Gialpha1.
Biochemistry, 36, 1997
1D2Z
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BU of 1d2z by Molmil
THREE-DIMENSIONAL STRUCTURE OF A COMPLEX BETWEEN THE DEATH DOMAINS OF PELLE AND TUBE
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DEATH DOMAIN OF PELLE, DEATH DOMAIN OF TUBE
著者Xiao, T, Towb, P, Wasserman, S.A, Sprang, S.R.
登録日1999-09-28
公開日1999-11-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Three-dimensional structure of a complex between the death domains of Pelle and Tube.
Cell(Cambridge,Mass.), 99, 1999
1AZT
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BU of 1azt by Molmil
GS-ALPHA COMPLEXED WITH GTP-GAMMA-S
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GS-ALPHA, MAGNESIUM ION, ...
著者Tesmer, J.J.G, Sprang, S.R.
登録日1997-11-20
公開日1998-02-25
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the adenylyl cyclase activator Gsalpha
Science, 278, 1997
1CUL
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BU of 1cul by Molmil
COMPLEX OF GS-ALPHA WITH THE CATALYTIC DOMAINS OF MAMMALIAN ADENYLYL CYCLASE: COMPLEX WITH 2',5'-DIDEOXY-ADENOSINE 3'-TRIPHOSPHATE AND MG
分子名称: 2',5'-DIDEOXY-ADENOSINE 3'-MONOPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, ...
著者Tesmer, J.J.G, Dessauer, C.A, Sunahara, R.K, Johnson, R.A, Gilman, A.G, Sprang, S.R.
登録日1999-08-20
公開日2001-01-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis for P-site inhibition of adenylyl cyclase.
Biochemistry, 39, 2000
1AZS
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BU of 1azs by Molmil
COMPLEX OF GS-ALPHA WITH THE CATALYTIC DOMAINS OF MAMMALIAN ADENYLYL CYCLASE
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GS-ALPHA, IIC2, ...
著者Tesmer, J.J.G, Sprang, S.R.
登録日1997-11-20
公開日1998-02-25
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS.
Science, 278, 1997
1AGR
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COMPLEX OF ALF4-ACTIVATED GI-ALPHA-1 WITH RGS4
分子名称: CITRIC ACID, GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), GUANOSINE-5'-DIPHOSPHATE, ...
著者Tesmer, J.J.G, Sprang, S.R.
登録日1997-03-25
公開日1997-06-16
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysis.
Cell(Cambridge,Mass.), 89, 1997
1BH2
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A326S MUTANT OF AN INHIBITORY ALPHA SUBUNIT
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GUANINE NUCLEOTIDE-BINDING PROTEIN, MAGNESIUM ION
著者Mixon, M.B, Posner, B.A, Wall, M.A, Gilman, A.G, Sprang, S.R.
登録日1998-06-12
公開日1998-11-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The A326S mutant of Gialpha1 as an approximation of the receptor-bound state.
J.Biol.Chem., 273, 1998
1ANN
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ANNEXIN IV
分子名称: ANNEXIN IV, CALCIUM ION
著者Sutton, R.B, Sprang, S.R.
登録日1995-09-21
公開日1996-01-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Three Dimensional Structure of Annexin IV
Annexins: Molecular Structure to Cellular Function, 1996
1A25
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C2 DOMAIN FROM PROTEIN KINASE C (BETA)
分子名称: CALCIUM ION, O-PHOSPHOETHANOLAMINE, PROTEIN KINASE C (BETA)
著者Sutton, R.B, Sprang, S.R.
登録日1998-01-16
公開日1998-05-06
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of the protein kinase Cbeta phospholipid-binding C2 domain complexed with Ca2+.
Structure, 6, 1998
1EDY
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CRYSTAL STRUCTURE OF RAT ALPHA 1-MACROGLOBULIN RECEPTOR BINDING DOMAIN
分子名称: ALPHA 1-MACROGLOBULIN
著者Xiao, T, DeCamp, D.L, Sprang, S.R.
登録日2000-01-28
公開日2000-12-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of a rat alpha 1-macroglobulin receptor-binding domain dimer.
Protein Sci., 9, 2000
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