4HHE
 
 | | Quinolinate synthase from Pyrococcus furiosus | | Descriptor: | CHLORIDE ION, Quinolinate synthase A | | Authors: | Soriano, E.V, Zhang, Y, Settembre, E.C, Colabroy, K, Sanders, J.M, Dorrestein, P.C, Begley, T.P, Ealick, S.E. | | Deposit date: | 2012-10-09 | | Release date: | 2013-08-28 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.797 Å) | | Cite: | Active-site models for complexes of quinolinate synthase with substrates and intermediates.
Acta Crystallogr.,Sect.D, 69, 2013
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5LIH
 | | Structure of a peptide-substrate bound to PKCiota core kinase domain | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MANGANESE (II) ION, ... | | Authors: | Soriano, E.V, Purkiss, A.G, McDonald, N.Q. | | Deposit date: | 2016-07-14 | | Release date: | 2016-09-14 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | aPKC Inhibition by Par3 CR3 Flanking Regions Controls Substrate Access and Underpins Apical-Junctional Polarization.
Dev.Cell, 38, 2016
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5LI1
 | | Structure of a Par3-inhibitory peptide bound to PKCiota core kinase domain | | Descriptor: | GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Soriano, E.V, Purkiss, A.G, McDonald, N.Q. | | Deposit date: | 2016-07-13 | | Release date: | 2016-09-14 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | aPKC Inhibition by Par3 CR3 Flanking Regions Controls Substrate Access and Underpins Apical-Junctional Polarization.
Dev.Cell, 38, 2016
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8R3X
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2QQD
 | | N47A mutant of Pyruvoyl-dependent Arginine Decarboxylase from Methanococcus jannashii | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, AGMATINE, PYRUVIC ACID, ... | | Authors: | Ealick, S.E, Soriano, E.S. | | Deposit date: | 2007-07-26 | | Release date: | 2008-03-18 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structures of the N47A and E109Q mutant proteins of pyruvoyl-dependent arginine decarboxylase from Methanococcus jannaschii.
Acta Crystallogr.,Sect.D, 64, 2008
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2QRO
 | | Human Deoxycytidine kinase dAMP, UDP, Mg ion product complex | | Descriptor: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, Deoxycytidine kinase, MAGNESIUM ION, ... | | Authors: | Ealick, S.E, Soriano, E.V. | | Deposit date: | 2007-07-28 | | Release date: | 2007-12-11 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.45 Å) | | Cite: | Structures of human deoxycytidine kinase product complexes.
Acta Crystallogr.,Sect.D, 63, 2007
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3ZH8
 | | A novel small molecule aPKC inhibitor | | Descriptor: | (2S)-3-phenyl-N~1~-[2-(pyridin-4-yl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl]propane-1,2-diamine, 1,2-ETHANEDIOL, CHLORIDE ION, ... | | Authors: | Kjaer, S, Purkiss, A.G, Kostelecky, B, Knowles, P.P, Soriano, E, Murray-Rust, J, McDonald, N.Q. | | Deposit date: | 2012-12-20 | | Release date: | 2013-02-27 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.739 Å) | | Cite: | Adenosine-Binding Motif Mimicry and Cellular Effects of a Thieno[2,3-D]Pyrimidine-Based Chemical Inhibitor of Atypical Protein Kinase C Isozymes.
Biochem.J., 451, 2013
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2QQC
 | | E109Q mutant of Pyruvoyl-dependent Arginine Decarboxylase from Methanococcus jannashii | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, AGMATINE, Pyruvoyl-dependent arginine decarboxylase subunit alpha, ... | | Authors: | Ealick, S.E, Soriano, E.S. | | Deposit date: | 2007-07-26 | | Release date: | 2008-03-18 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structures of the N47A and E109Q mutant proteins of pyruvoyl-dependent arginine decarboxylase from Methanococcus jannaschii.
Acta Crystallogr.,Sect.D, 64, 2008
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2QRN
 | | Human Deoxycytidine kinase dCMP, UDP, Mg ion product complex | | Descriptor: | 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, Deoxycytidine kinase, MAGNESIUM ION, ... | | Authors: | Ealick, S.E, Soriano, E.V. | | Deposit date: | 2007-07-28 | | Release date: | 2007-12-11 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structures of human deoxycytidine kinase product complexes.
Acta Crystallogr.,Sect.D, 63, 2007
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2QRY
 | | Periplasmic thiamin binding protein | | Descriptor: | THIAMIN PHOSPHATE, Thiamine-binding periplasmic protein | | Authors: | Ealick, S.E, Soriano, E.V. | | Deposit date: | 2007-07-30 | | Release date: | 2008-02-05 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structural Similarities between Thiamin-Binding Protein and Thiaminase-I Suggest a Common Ancestor
Biochemistry, 47, 2008
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