1HX1
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![BU of 1hx1 by Molmil](/molmil-images/mine/1hx1) | CRYSTAL STRUCTURE OF A BAG DOMAIN IN COMPLEX WITH THE HSC70 ATPASE DOMAIN | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAG family molecular chaperone regulator 1, Heat shock 70 kDa protein 8 | Authors: | Sondermann, H, Scheufler, C, Moarefi, I. | Deposit date: | 2001-01-11 | Release date: | 2001-03-07 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of a Bag/Hsc70 complex: convergent functional evolution of Hsp70 nucleotide exchange factors. Science, 291, 2001
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1XD2
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![BU of 1xd2 by Molmil](/molmil-images/mine/1xd2) | Crystal Structure of a ternary Ras:SOS:Ras*GDP complex | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Sondermann, H, Soisson, S.M, Boykevisch, S, Yang, S.S, Bar-Sagi, D, Kuriyan, J. | Deposit date: | 2004-09-03 | Release date: | 2004-11-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural analysis of autoinhibition in the ras activator son of sevenless. Cell(Cambridge,Mass.), 119, 2004
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1Q9C
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1XDV
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![BU of 1xdv by Molmil](/molmil-images/mine/1xdv) | Experimentally Phased Structure of Human the Son of Sevenless protein at 4.1 Ang. | Descriptor: | Son of sevenless protein homolog 1 | Authors: | Sondermann, H, Soisson, S.M, Boykevisch, S, Yang, S.S, Bar-Sagi, D, Kuriyan, J. | Deposit date: | 2004-09-08 | Release date: | 2004-11-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (4.1 Å) | Cite: | Structural analysis of autoinhibition in the ras activator son of sevenless. Cell(Cambridge,Mass.), 119, 2004
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1XD4
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![BU of 1xd4 by Molmil](/molmil-images/mine/1xd4) | Crystal structure of the DH-PH-cat module of Son of Sevenless (SOS) | Descriptor: | Son of sevenless protein homolog 1 | Authors: | Sondermann, H, Soisson, S.M, Boykevisch, S, Yang, S.S, Bar-Sagi, D, Kuriyan, J. | Deposit date: | 2004-09-03 | Release date: | 2004-11-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.64 Å) | Cite: | Structural analysis of autoinhibition in the ras activator son of sevenless. Cell(Cambridge,Mass.), 119, 2004
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3PJX
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![BU of 3pjx by Molmil](/molmil-images/mine/3pjx) | |
4KKQ
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![BU of 4kkq by Molmil](/molmil-images/mine/4kkq) | |
4KKR
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![BU of 4kkr by Molmil](/molmil-images/mine/4kkr) | |
4KKP
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![BU of 4kkp by Molmil](/molmil-images/mine/4kkp) | |
3PJV
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3PJT
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![BU of 3pjt by Molmil](/molmil-images/mine/3pjt) | Structure of Pseudomonas fluorescence LapD EAL domain complexed with c-di-GMP, C2221 | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Cyclic dimeric GMP binding protein | Authors: | Sondermann, H, Navarro, M.V.A.S, Krasteva, P. | Deposit date: | 2010-11-10 | Release date: | 2011-02-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5154 Å) | Cite: | Structural Basis for c-di-GMP-Mediated Inside-Out Signaling Controlling Periplasmic Proteolysis. Plos Biol., 9, 2011
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3PJU
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![BU of 3pju by Molmil](/molmil-images/mine/3pju) | Structure of Pseudomonas fluorescence LapD EAL domain complexed with c-di-GMP, P6522 | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Cyclic dimeric GMP binding protein | Authors: | Sondermann, H, Navarro, M.V.A.S, Krasteva, P. | Deposit date: | 2010-11-10 | Release date: | 2011-02-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4991 Å) | Cite: | Structural Basis for c-di-GMP-Mediated Inside-Out Signaling Controlling Periplasmic Proteolysis. Plos Biol., 9, 2011
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3PJW
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![BU of 3pjw by Molmil](/molmil-images/mine/3pjw) | |
7OL3
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![BU of 7ol3 by Molmil](/molmil-images/mine/7ol3) | Human ATL1 N417ins (catalytic core) | Descriptor: | Atlastin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Kelly, C.M, Sondermann, H. | Deposit date: | 2021-05-19 | Release date: | 2021-07-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A novel insertion mutation in atlastin 1 is associated with spastic quadriplegia, increased membrane tethering, and aberrant conformational switching. J.Biol.Chem., 298, 2021
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4U65
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![BU of 4u65 by Molmil](/molmil-images/mine/4u65) | Structure of the periplasmic output domain of the Legionella pneumophila LapD ortholog CdgS9 in complex with Pseudomonas fluorescens LapG | Descriptor: | CALCIUM ION, Putative cystine protease, Two component histidine kinase, ... | Authors: | Chatterjee, D, Cooley, R.B, Boyd, C.D, Mehl, R.A, O'Toole, G.A, Sondermann, H.S. | Deposit date: | 2014-07-27 | Release date: | 2014-08-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Mechanistic insight into the conserved allosteric regulation of periplasmic proteolysis by the signaling molecule cyclic-di-GMP. Elife, 3, 2014
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6PWK
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![BU of 6pwk by Molmil](/molmil-images/mine/6pwk) | Vibrio cholerae LapD S helix-GGDEF-EAL (bound to c-di-GMP) | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), GGDEF and EAL domain-containing protein, MAGNESIUM ION | Authors: | Giglio, K.M, Cooley, R.B, Sondermann, H. | Deposit date: | 2019-07-23 | Release date: | 2019-10-09 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | A Conserved Regulatory Circuit Controls Large Adhesins in Vibrio cholerae. Mbio, 10, 2019
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6PWJ
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3BRE
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![BU of 3bre by Molmil](/molmil-images/mine/3bre) | Crystal Structure of P.aeruginosa PA3702 | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, Probable two-component response regulator | Authors: | De, N, Pirruccello, M, Krasteva, P.V, Bae, N, Raghavan, R.V, Sondermann, H. | Deposit date: | 2007-12-21 | Release date: | 2008-04-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Phosphorylation-independent regulation of the diguanylate cyclase WspR. Plos Biol., 6, 2008
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6XJO
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4U64
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![BU of 4u64 by Molmil](/molmil-images/mine/4u64) | Structure of the periplasmic output domain of the Legionella pneumophila LapD ortholog CdgS9 in the apo state | Descriptor: | Two component histidine kinase, GGDEF domain protein/EAL domain protein | Authors: | Chatterjee, D, Cooley, R.B, Boyd, C.D, Mehl, R.A, O'Toole, G.A, Sondermann, H.S. | Deposit date: | 2014-07-27 | Release date: | 2014-08-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.141 Å) | Cite: | Mechanistic insight into the conserved allosteric regulation of periplasmic proteolysis by the signaling molecule cyclic-di-GMP. Elife, 3, 2014
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5VGR
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![BU of 5vgr by Molmil](/molmil-images/mine/5vgr) | Human Atlastin-3, GDP-bound | Descriptor: | Atlastin-3, GUANOSINE-5'-DIPHOSPHATE | Authors: | O'Donnell, J.P, Sondermann, H. | Deposit date: | 2017-04-11 | Release date: | 2017-05-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.096 Å) | Cite: | Timing and Reset Mechanism of GTP Hydrolysis-Driven Conformational Changes of Atlastin. Structure, 25, 2017
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6XJN
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![BU of 6xjn by Molmil](/molmil-images/mine/6xjn) | |
2II0
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![BU of 2ii0 by Molmil](/molmil-images/mine/2ii0) | Crystal Structure of catalytic domain of Son of sevenless (Rem-Cdc25) in the absence of Ras | Descriptor: | Son of sevenless homolog 1 | Authors: | Freedman, T.S, Sondermann, H, Friedland, G.D, Kortemme, T, Bar-Sagi, D, Marqusee, S, Kuriyan, J. | Deposit date: | 2006-09-27 | Release date: | 2006-10-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | A Ras-induced conformational switch in the Ras activator Son of sevenless. Proc.Natl.Acad.Sci.Usa, 103, 2006
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4FGP
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![BU of 4fgp by Molmil](/molmil-images/mine/4fgp) | Legionella pneumophila LapG (EGTA-treated) | Descriptor: | Periplasmic protein | Authors: | Chatterjee, D, Boyd, C.D, O'Toole, G.A, Sondermann, H. | Deposit date: | 2012-06-04 | Release date: | 2012-06-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Structural characterization of a conserved, calcium-dependent periplasmic protease from Legionella pneumophila. J.Bacteriol., 194, 2012
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4FGQ
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![BU of 4fgq by Molmil](/molmil-images/mine/4fgq) | Legionella pneumophila LapG | Descriptor: | Periplasmic protein | Authors: | Chatterjee, D, Boyd, C.D, O'Toole, G.A, Sondermann, H. | Deposit date: | 2012-06-04 | Release date: | 2012-06-20 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.645 Å) | Cite: | Structural characterization of a conserved, calcium-dependent periplasmic protease from Legionella pneumophila. J.Bacteriol., 194, 2012
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