8CIE
 
 | | Crystal structure of the human CDKL5 kinase domain with compound YL-354 | | 分子名称: | 4-[[3,5-bis(fluoranyl)phenyl]carbonylamino]-~{N}-piperidin-4-yl-1~{H}-pyrazole-3-carboxamide, Cyclin-dependent kinase-like 5, SULFATE ION | | 著者 | Richardson, W, Chen, X, Newman, J.A, Bakshi, S, Lakshminarayana, B, Brooke, L, Bullock, A.N. | | 登録日 | 2023-02-09 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective.
Acs Chem Neurosci, 14, 2023
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4Z0C
 | | Crystal structure of TLR13-ssRNA13 complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DNA (5'-R(P*AP*CP*GP*GP*AP*AP*AP*GP*AP*CP*CP*CP*C)-3'), ... | | 著者 | Song, W, Han, Z, Chai, J. | | 登録日 | 2015-03-26 | | 公開日 | 2015-10-07 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for specific recognition of single-stranded RNA by Toll-like receptor 13
Nat.Struct.Mol.Biol., 22, 2015
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8A8E
 | | PPSA C terminal octahedral structure | | 分子名称: | Phosphoenolpyruvate synthase | | 著者 | Song, W. | | 登録日 | 2022-06-22 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Survival strategies in the heat Lysine acetylation stabilizes the quaternary structure of a Mega-Dalton hyperthermophilic PEP-synthase
To Be Published
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7XOZ
 | | Crystal structure of RPPT-TIR | | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase | | 著者 | Song, W, Jia, A, Huang, S, Chai, J. | | 登録日 | 2022-05-02 | | 公開日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | | 主引用文献 | TIR-catalyzed ADP-ribosylation reactions produce signaling molecules for plant immunity.
Science, 377, 2022
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5HYX
 | | Plant peptide hormone receptor RGFR1 in complex with RGF1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PTR-SER-ASN-PRO-GLY-HIS-HIS-PRO-HYP-ARG-HIS-ASN, ... | | 著者 | Song, W, Han, Z, Chai, J. | | 登録日 | 2016-02-02 | | 公開日 | 2017-01-11 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.596 Å) | | 主引用文献 | Signature motif-guided identification of receptors for peptide hormones essential for root meristem growth
Cell Res., 26, 2016
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5HZ3
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5HZ0
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5HZ1
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6MPV
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8HR6
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8HPE
 | | Crystal structure of Leucine dehydrogenase | | 分子名称: | GLYCEROL, Leucine dehydrogenase, SULFATE ION | | 著者 | Li, X, Song, W. | | 登録日 | 2022-12-12 | | 公開日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | | 主引用文献 | A Tri-Enzyme Cascade for Efficient Production of L-2-Aminobutyrate from L-Threonine.
Chembiochem, 24, 2023
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7O2T
 | | PqsR (MvfR) in complex with antagonist 61 | | 分子名称: | 2-[4-[(2S)-3-(6-chloro-4-oxoquinazolin-3-yl)-2-hydroxypropoxy]phenyl]acetonitrile, LysR family transcriptional regulator | | 著者 | Emsley, J, Richardson, W. | | 登録日 | 2021-03-31 | | 公開日 | 2022-04-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | PqsR (MvfR) in complex with antagonist 61
To Be Published
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7O2U
 | | PqsR (MvfR) in complex with antagonist 40 | | 分子名称: | 2-[4-[(2S)-3-(6-chloranyl-4-oxidanylidene-quinazolin-3-yl)-2-oxidanyl-propoxy]phenoxy]ethanenitrile, LysR family transcriptional regulator | | 著者 | Emsley, J, Richardson, W. | | 登録日 | 2021-03-31 | | 公開日 | 2022-04-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | PqsR (MvfR) in complex with antagonist 40
To Be Published
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8HP4
 | | CtPDC complex | | 分子名称: | MAGNESIUM ION, Pyruvate decarboxylase, THIAMINE DIPHOSPHATE | | 著者 | Xu, H.H, Song, W. | | 登録日 | 2022-12-11 | | 公開日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | | 主引用文献 | Protein engineering of pyruvate decarboxylase to remove the rate-limiting bottleneck in the cascade pathway of tyrosol synthesis
To Be Published
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8HP2
 | | CtPDC | | 分子名称: | Pyruvate decarboxylase | | 著者 | Xu, H.H, Song, W. | | 登録日 | 2022-12-11 | | 公開日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Protein engineering of pyruvate decarboxylase to remove the rate-limiting bottleneck in the cascade pathway of tyrosol synthesis
To Be Published
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3N9I
 | | Crystal structure of tryptophanyl-tRNA synthetase from Yersinia pestis CO92 | | 分子名称: | CALCIUM ION, GLYCEROL, Tryptophanyl-tRNA synthetase | | 著者 | Nocek, B, Maltseva, N, Papazisi, L, Anderson, W, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2010-05-30 | | 公開日 | 2010-07-21 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of tryptophanyl-tRNA synthetase from Yersinia pestis CO92
TO BE PUBLISHED
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3N2A
 | | Crystal structure of bifunctional folylpolyglutamate synthase/dihydrofolate synthase from Yersinia pestis CO92 | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Bifunctional folylpolyglutamate synthase/dihydrofolate synthase, ... | | 著者 | Nocek, B, Maltseva, N, Papazisi, L, Anderson, W, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2010-05-17 | | 公開日 | 2010-06-30 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of bifunctional folylpolyglutamate synthase/dihydrofolate synthase from Yersinia pestis CO92
TO BE PUBLISHED
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4D09
 | | PDE2a catalytic domain in complex with a brain penetrant inhibitor | | 分子名称: | CGMP-DEPENDENT 3', 5'-CYCLIC PHOSPHODIESTERASE, MAGNESIUM ION, ... | | 著者 | Buijnsters, P, Andres, J.I, DeAngelis, M, Langlois, X, Rombouts, F, Sanderson, W, Tresadern, G, Trabanco, A, VanHoof, G, VanRoosbroeck, Y. | | 登録日 | 2014-04-24 | | 公開日 | 2014-08-06 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure-Based Design of a Potent, Selective, and Brain Penetrating Pde2 Inhibitor with Demonstrated Target Engagement.
Acs Med.Chem.Lett., 5, 2014
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9FGO
 | | Crystal structure of Enterovirus 71 2A protease mutant C110A containing VP1-2A junction in the active site | | 分子名称: | CHLORIDE ION, Polyprotein, ZINC ION | | 著者 | Ni, X, Koekemoer, L, Williams, E.P, Wang, S, Wright, N.D, Godoy, A.S, Aschenbrenner, J.C, Balcomb, B.H, Lithgo, R.M, Marples, P.G, Fairhead, M, Thompson, W, Kirkegaard, K, Fearon, D, Walsh, M.A, von Delft, F. | | 登録日 | 2024-05-24 | | 公開日 | 2024-09-04 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Crystal structure of Enterovirus 71 2A protease mutant C110A containing VP1-2A junction in the active site
To Be Published
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1K8I
 | | CRYSTAL STRUCTURE OF MOUSE H2-DM | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II H2-M alpha chain, MHC class II H2-M beta 2 chain | | 著者 | Fremont, D.H, Crawford, F, Marrack, P, Hendrickson, W, Kappler, J. | | 登録日 | 2001-10-24 | | 公開日 | 2001-12-05 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Crystal structure of mouse H2-M.
Immunity, 9, 1998
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2M6M
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2LJ2
 | | Integral membrane core domain of the mercury transporter MerF in lipid bilayer membranes | | 分子名称: | MerF | | 著者 | Das, B.B, Nothnagel, H.J, Lu, G.J, Son, W, Park, S, Tian, Y.B, Marassi, F.M, Opella, S.J. | | 登録日 | 2011-09-03 | | 公開日 | 2012-01-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | Structure determination of a membrane protein in proteoliposomes.
J.Am.Chem.Soc., 134, 2012
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2KLV
 | | Membrane-bound structure of the Pf1 major coat protein in DHPC micelle | | 分子名称: | Capsid protein G8P | | 著者 | Park, S, Son, W, Mukhopadhyay, R, Valafar, H, Opella, S.J. | | 登録日 | 2009-07-08 | | 公開日 | 2009-10-06 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Phage-induced alignment of membrane proteins enables the measurement and structural analysis of residual dipolar couplings with dipolar waves and lambda-maps.
J.Am.Chem.Soc., 131, 2009
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2K6P
 | | Solution Structure of hypothetical protein, HP1423 | | 分子名称: | Uncharacterized protein HP_1423 | | 著者 | Kim, J, Park, S, Lee, K, Son, W, Sohn, N, Lee, B. | | 登録日 | 2008-07-15 | | 公開日 | 2009-06-16 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of hypothetical protein HP1423 (Y1423_HELPY) reveals the presence of alphaL motif related to RNA binding
Proteins, 75, 2009
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3KD3
 | | Crystal structure of a phosphoserine phosphohydrolase-like protein from Francisella tularensis subsp. tularensis SCHU S4 | | 分子名称: | GLYCEROL, MAGNESIUM ION, Phosphoserine phosphohydrolase-like protein | | 著者 | Nocek, B, Zhou, M, Peterson, S, Anderson, W, Joachimiak, A, CSGID, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2009-10-22 | | 公開日 | 2009-12-15 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of a phosphoserine phosphohydrolase-like protein from Francisella tularensis subsp. tularensis SCHUS4
TO BE PUBLISHED
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