4ZV9
 
 | | 2.00 Angstrom resolution crystal structure of an uncharacterized protein from Escherichia coli O157:H7 str. Sakai | | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, PHOSPHATE ION, ... | | Authors: | Halavaty, A.S, Wawrzak, Z, Filippova, E.V, Kiryukhina, O, Endres, M, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2015-05-18 | | Release date: | 2015-06-17 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | 2.00 Angstrom resolution crystal structure of an uncharacterized protein from Escherichia coli O157:H7 str. Sakai
To Be Published
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5T1V
 | | Crystal structure of Zika virus NS2B-NS3 protease in apo-form. | | Descriptor: | NS2B-NS3 protease,NS2B-NS3 protease | | Authors: | Nocadello, S, Light, S.H, Minasov, G, Shuvalova, L, Cardona-Correa, A.A, Ojeda, I, Vargas, J, Johnson, M.E, Lee, H, Anderson, W.F, Center for Structural Genomics of Infectious Diseases, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2016-08-22 | | Release date: | 2016-09-07 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Crystal structure of Zika virus NS2B-NS3 protease in apo-form.
To Be Published
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4JRR
 | | Crystal structure of disulfide bond oxidoreductase DsbA1 from Legionella pneumophila | | Descriptor: | GLYCEROL, SULFATE ION, Thiol:disulfide interchange protein DsbA | | Authors: | Shumilin, I.A, Jameson-Lee, M, Cymborowski, M, Domagalski, M.J, Chertihin, O, Kpadeh, Z.Z, Yeh, A.J, Hoffman, P.S, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2013-03-21 | | Release date: | 2013-04-24 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Crystal structure of disulfide bond oxidoreductase DsbA1 from Legionella pneumophila
To be Published
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3TL2
 | | Crystal structure of Bacillus anthracis str. Ames malate dehydrogenase in closed conformation. | | Descriptor: | 1,2-ETHANEDIOL, Malate dehydrogenase, THIOCYANATE ION | | Authors: | Blus, B.J, Chruszcz, M, Tkaczuk, K.L, Osinski, T, Cymborowski, M, Kudritska, M, Grimshaw, S, Savchenko, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2011-08-29 | | Release date: | 2011-09-21 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of Bacillus anthracis str. Ames malate dehydrogenase in closed conformation.
TO BE PUBLISHED
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4WB6
 | | Crystal structure of a L205R mutant of human cAMP-dependent protein kinase A (catalytic alpha subunit) | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PKI (5-24), ... | | Authors: | Cheung, J, Ginter, C, Cassidy, M, Franklin, M.C, Rudolph, M.J, Hendrickson, W.A. | | Deposit date: | 2014-09-02 | | Release date: | 2015-01-21 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural insights into mis-regulation of protein kinase A in human tumors.
Proc.Natl.Acad.Sci.USA, 112, 2015
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4WB5
 | | Crystal structure of human cAMP-dependent protein kinase A (catalytic alpha subunit) | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PKI (5-24), ... | | Authors: | Cheung, J, Ginter, C, Cassidy, M, Franklin, M.C, Rudolph, M.J, Hendrickson, W.A. | | Deposit date: | 2014-09-02 | | Release date: | 2015-01-21 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.641 Å) | | Cite: | Structural insights into mis-regulation of protein kinase A in human tumors.
Proc.Natl.Acad.Sci.USA, 112, 2015
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3UDU
 | | Crystal structure of putative 3-isopropylmalate dehydrogenase from Campylobacter jejuni | | Descriptor: | 1,2-ETHANEDIOL, 3-isopropylmalate dehydrogenase, CHLORIDE ION | | Authors: | Tkaczuk, K.L, Chruszcz, M, Grimshaw, S, Onopriyenko, O, Savchenko, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2011-10-28 | | Release date: | 2011-11-09 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Crystal structure of putative 3-isopropylmalate dehydrogenase from Campylobacter jejuni
To be Published
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7WRG
 | | Crystal structure of full-length kinesin-3 KLP-6 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein, MAGNESIUM ION | | Authors: | Wang, W.J, Ren, J.Q, Song, W.Y, Feng, W. | | Deposit date: | 2022-01-26 | | Release date: | 2022-08-10 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.16 Å) | | Cite: | The architecture of kinesin-3 KLP-6 reveals a multilevel-lockdown mechanism for autoinhibition.
Nat Commun, 13, 2022
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3TOZ
 | | 2.2 Angstrom Crystal Structure of Shikimate 5-dehydrogenase from Listeria monocytogenes in Complex with NAD. | | Descriptor: | CHLORIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ... | | Authors: | Minasov, G, Light, S.H, Halavaty, A, Shuvalova, L, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2011-09-06 | | Release date: | 2011-09-21 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | 2.2 Angstrom Crystal Structure of Shikimate 5-dehydrogenase from Listeria monocytogenes in Complex with NAD.
TO BE PUBLISHED
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3TYS
 | | Crystal structure of transcriptional regulator VanUg, Form II | | Descriptor: | Predicted transcriptional regulator | | Authors: | Stogios, P.J, Evdokimova, E, Wawrzak, Z, Depardieu, F, Courvalin, P, Shabalin, I, Chruszcz, M, Minor, W, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2011-09-26 | | Release date: | 2011-10-12 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.121 Å) | | Cite: | Crystal structure of transcriptional regulator VanUg, Form II
TO BE PUBLISHED
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4EWQ
 | | Human p38 alpha MAPK in complex with a pyridazine based inhibitor | | Descriptor: | 3-phenyl-4-(pyridin-4-yl)-6-[4-(pyrimidin-2-yl)piperazin-1-yl]pyridazine, 4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE, ACETATE ION, ... | | Authors: | Grum-Tokars, V, Minasov, G, Roy, S, Schavocky, J, Winsor, J, Watterson, D.M, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2012-04-27 | | Release date: | 2012-06-27 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | A Selective and Brain Penetrant p38 alpha MAPK Inhibitor Candidate for Neurologic and Neuropsychiatric Disorders That Attenuates Neuroinflammation and Cognitive Dysfunction.
J.Med.Chem., 62, 2019
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3TYR
 | | Crystal structure of transcriptional regulator VanUg, Form I | | Descriptor: | Transcriptional regulator | | Authors: | Stogios, P.J, Evdokimova, E, Wawrzak, Z, Dong, A, Depardieu, F, Courvalin, P, Shabalin, I, Chruszcz, M, Minor, W, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2011-09-26 | | Release date: | 2011-10-12 | | Last modified: | 2022-04-13 | | Method: | X-RAY DIFFRACTION (1.699 Å) | | Cite: | Crystal structure of transcriptional regulator VanUg, Form I
TO BE PUBLISHED
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4YF1
 | | 1.85 angstrom crystal structure of lmo0812 from Listeria monocytogenes EGD-e | | Descriptor: | CITRATE ANION, Lmo0812 protein, SODIUM ION | | Authors: | Krishna, S.N, Light, S.H, Filippova, E.V, Minasov, G, Kiryukhina, O, Jedrzejczak, R, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2015-02-24 | | Release date: | 2015-03-04 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | 1.85 angstrom crystal structure of lmo0812 from Listeria monocytogenes EGD-e
To Be Published
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7BAT
 | | A hexameric barrel state of a de novo coiled-coil assembly: CC-Type2-(GgIaId)4 | | Descriptor: | CC-Type2-(GgIaId)4, N-PROPANOL | | Authors: | Martin, F.J.O, Dawson, W.M, Shelley, K, Brady, R.L, Woolfson, D.N. | | Deposit date: | 2020-12-16 | | Release date: | 2021-04-28 | | Last modified: | 2021-11-17 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Coiled coils 9-to-5: rational de novo design of alpha-helical barrels with tunable oligomeric states.
Chem Sci, 12, 2021
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7BAS
 | | A de novo pentameric coiled-coil assembly: CC-Type2-(TgLaId)4-W19BrPhe. | | Descriptor: | CC-Type2-(TgLaId)4-W19BrPhe. | | Authors: | Martin, F.J.O, Dawson, W.M, Shelley, K, Brady, R.L, Woolfson, D.N. | | Deposit date: | 2020-12-16 | | Release date: | 2021-04-28 | | Last modified: | 2021-11-17 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Coiled coils 9-to-5: rational de novo design of alpha-helical barrels with tunable oligomeric states.
Chem Sci, 12, 2021
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7BAV
 | | A de novo pentameric coiled-coil assembly: CC-Type2-(TgLaId)4-W19BrPhe. | | Descriptor: | CC-Type2-(TgLaId)4-W19BrPhe | | Authors: | Martin, F.J.O, Dawson, W.M, Shelley, K, Brady, R.L, Woolfson, D.N. | | Deposit date: | 2020-12-16 | | Release date: | 2021-04-28 | | Last modified: | 2021-11-17 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Coiled coils 9-to-5: rational de novo design of alpha-helical barrels with tunable oligomeric states.
Chem Sci, 12, 2021
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7BAW
 | | A heptameric barrel state of a de novo coiled-coil assembly: CC-Type2-(GgIaId)4 | | Descriptor: | CC-Type2-(GgIaId)4, GLYCEROL, N-PROPANOL | | Authors: | Martin, F.J.O, Dawson, W.M, Brady, R.L, Woolfson, D.N. | | Deposit date: | 2020-12-16 | | Release date: | 2021-04-28 | | Last modified: | 2021-11-17 | | Method: | X-RAY DIFFRACTION (1.71 Å) | | Cite: | Coiled coils 9-to-5: rational de novo design of alpha-helical barrels with tunable oligomeric states.
Chem Sci, 12, 2021
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3UDO
 | | Crystal structure of putative isopropylamlate dehydrogenase from Campylobacter jejuni | | Descriptor: | 1,2-ETHANEDIOL, 3-isopropylmalate dehydrogenase, SULFATE ION | | Authors: | Tkaczuk, K.L, Chruszcz, M, Blus, B.J, Onopriyenko, O, Grimshaw, S, Savchenko, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2011-10-28 | | Release date: | 2011-11-09 | | Last modified: | 2022-04-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of putative isopropylamlate dehydrogenase from Campylobacter jejuni
To be Published
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4ZND
 | | 2.55 Angstrom resolution structure of 3-phosphoshikimate 1-carboxyvinyltransferase (AroA) from Coxiella burnetii in complex with shikimate-3-phosphate, phosphate, and potassium | | Descriptor: | 3-phosphoshikimate 1-carboxyvinyltransferase, BETA-MERCAPTOETHANOL, PHOSPHATE ION, ... | | Authors: | Light, S.H, Minasov, G, Krishna, S.N, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2015-05-04 | | Release date: | 2015-05-13 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | 2.55 Angstrom resolution structure of 3-phosphoshikimate 1-carboxyvinyltransferase (AroA) from Coxiella burnetii in complex with shikimate-3-phosphate, phosphate, and potassium
To Be Published
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5HM3
 | | 2.25 Angstrom Resolution Crystal Structure of Long-chain-fatty-acid-AMP Ligase FadD32 from Mycobacterium tuberculosis in complex with Inhibitor 5'-O-[(11-phenoxyundecanoyl)sulfamoyl]adenosine | | Descriptor: | 5'-O-[(11-phenoxyundecanoyl)sulfamoyl]adenosine, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Minasov, G, Warwrzak, Z, Kuhn, M.L, Shuvalova, L, Flores, K.J, Wilson, D.J, Grimes, K.D, Aldrich, C.C, Anderson, W.A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2016-01-15 | | Release date: | 2016-08-03 | | Last modified: | 2016-09-07 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structure of the Essential Mtb FadD32 Enzyme: A Promising Drug Target for Treating Tuberculosis.
Acs Infect Dis., 2, 2016
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3UXJ
 | | Crystal Structure of 7-cyano-7-deazaguanine reductase, QueF from Vibrio cholerae complexed with NADP and PreQ0 | | Descriptor: | 1,2-ETHANEDIOL, 7-DEAZA-7-AMINOMETHYL-GUANINE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Kim, Y, Zhang, R, Gu, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2011-12-05 | | Release date: | 2012-01-04 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (1.401 Å) | | Cite: | Crystal Structure of 7-cyano-7-deazaguanine reductase, QueF from
Vibrio cholerae complexed with NADP and PreQ0
To be Published, 2012
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3UWD
 | | Crystal Structure of Phosphoglycerate Kinase from Bacillus Anthracis | | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Zheng, H, Chruszcz, M, Porebski, P, Kudritska, M, Grimshaw, S, Savchenko, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2011-12-01 | | Release date: | 2012-01-11 | | Last modified: | 2022-04-13 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Crystal structures of putative phosphoglycerate kinases from B. anthracis and C. jejuni.
J.Struct.Funct.Genom., 13, 2012
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3GVD
 | | Crystal Structure of Serine Acetyltransferase CysE from Yersinia pestis | | Descriptor: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, ACETIC ACID, CYSTEINE, ... | | Authors: | Kim, Y, Zhou, M, Peterson, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2009-03-30 | | Release date: | 2009-05-12 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal Structure of Serine Acetyltransferase CysE from Yersinia pestis
To be Published
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3UUW
 | | 1.63 Angstrom Resolution Crystal Structure of Dehydrogenase (MviM) from Clostridium difficile. | | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | Authors: | Minasov, G, Wawrzak, Z, Kudritska, M, Grimshaw, S, Papazisi, L, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2011-11-28 | | Release date: | 2011-12-21 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | 1.63 Angstrom Resolution Crystal Structure of Dehydrogenase (MviM) from Clostridium difficile.
TO BE PUBLISHED
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6KNT
 | | Crystal structure of the metallo-beta-lactamase fold protein YhfI from Bacillus subtilis (space group P4332) | | Descriptor: | Putative metal-dependent hydrolase, ZINC ION | | Authors: | Na, H.W, Namgung, B, Song, W.S, Yoon, S.I. | | Deposit date: | 2019-08-07 | | Release date: | 2019-09-18 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural and biochemical analyses of the metallo-beta-lactamase fold protein YhfI from Bacillus subtilis.
Biochem.Biophys.Res.Commun., 519, 2019
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