2C25
 
 | | 1.8A Crystal Structure of Psathyrella velutina lectin in complex with N-acetylneuraminic acid | | Descriptor: | CALCIUM ION, N-acetyl-alpha-neuraminic acid, PSATHYRELLA VELUTINA LECTIN PVL, ... | | Authors: | Cioci, G, Mitchell, E.P, Chazalet, V, Gautier, C, Oscarson, S, Debray, H, Perez, S, Imberty, A. | | Deposit date: | 2005-09-26 | | Release date: | 2006-01-23 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Beta-Propeller Crystal Structure of Psathyrella Velutina Lectin: An Integrin-Like Fungal Protein Interacting with Monosaccharides and Calcium.
J.Mol.Biol., 357, 2006
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1IGT
 | | STRUCTURE OF IMMUNOGLOBULIN | | Descriptor: | IGG2A INTACT ANTIBODY - MAB231, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Harris, L.J, Larson, S.B, Hasel, K.W, McPherson, A. | | Deposit date: | 1996-10-25 | | Release date: | 1997-07-07 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Refined structure of an intact IgG2a monoclonal antibody.
Biochemistry, 36, 1997
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1XCT
 | | Complex HCV core-Fab 19D9D6-Protein L mutant (D55A, L57H, Y64W) in space group P21212 | | Descriptor: | Capsid protein C, Monoclonal antibody 19D9D6 Heavy chain, Monoclonal antibody 19D9D6 Light chain, ... | | Authors: | Menez, R, Housden, N.G, Harrison, S, Jolivet-Reynaud, C, Gore, M.G, Stura, E.A. | | Deposit date: | 2004-09-03 | | Release date: | 2005-05-31 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | Different crystal packing in Fab-protein L semi-disordered peptide complex.
Acta Crystallogr.,Sect.D, 61, 2005
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1XF5
 | | Complex HCV core-Fab 19D9D6-Protein L mutant (H74C, Y64W)in space group P21212 | | Descriptor: | Capsid protein C, Monoclonal antibody 19D9D6 Heavy chain, Monoclonal antibody 19D9D6 Light chain, ... | | Authors: | Menez, R, Housden, N.G, Harrison, S, Jolivet-Reynaud, C, Gore, M.G, Stura, E.A. | | Deposit date: | 2004-09-14 | | Release date: | 2005-05-31 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Different crystal packing in Fab-protein L semi-disordered peptide complex.
Acta Crystallogr.,Sect.D, 61, 2005
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4F5X
 | | Location of the dsRNA-dependent polymerase, VP1, in rotavirus particles | | Descriptor: | Intermediate capsid protein VP6, RNA-directed RNA polymerase, VP2 protein, ... | | Authors: | Estrozi, L.F, Settembre, E.C, Goret, G, McClain, B, Zhang, X, Chen, J.Z, Grigorieff, N, Harrison, S.C. | | Deposit date: | 2012-05-13 | | Release date: | 2012-10-24 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (5 Å) | | Cite: | Location of the dsRNA-Dependent Polymerase, VP1, in Rotavirus Particles.
J.Mol.Biol., 425, 2013
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2HGX
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2HHF
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2FTX
 | | Crystal structure of the yeast kinetochore Spc24/Spc25 globular domain | | Descriptor: | Hypothetical 24.6 kDa protein in ILV2-ADE17 intergenic region, Hypothetical 25.2 kDa protein in AFG3-SEB2 intergenic region, PHOSPHATE ION, ... | | Authors: | Wei, R.R, Harrison, S.C. | | Deposit date: | 2006-01-25 | | Release date: | 2006-06-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Atomic Structure of the kinetochore Spc24p/Spc25p globular domain reveals a novel fold
To be Published
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1SLQ
 | | Crystal structure of the trimeric state of the rhesus rotavirus VP4 membrane interaction domain, VP5CT | | Descriptor: | VP4 | | Authors: | Dormitzer, P.R, Nason, E.B, Prasad, B.V.V, Harrison, S.C. | | Deposit date: | 2004-03-06 | | Release date: | 2004-08-31 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural rearrangements in the membrane penetration protein of a non-enveloped virus.
Nature, 430, 2004
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2HG8
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3IDI
 | | Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 Fab' fragment in complex with gp41 Peptide ALDKWNQ | | Descriptor: | 2F5 Fab heavy chain, 2F5 Fab light chain, GLYCEROL, ... | | Authors: | Julien, J.-P, Bryson, S, Pai, E.F. | | Deposit date: | 2009-07-21 | | Release date: | 2010-03-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystallographic definition of the epitope promiscuity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5: vaccine design implications.
J.Virol., 83, 2009
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2AJF
 | | Structure of SARS coronavirus spike receptor-binding domain complexed with its receptor | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme-Related Carboxypeptidase (Ace2), CHLORIDE ION, ... | | Authors: | Li, F, Li, W, Farzan, M, Harrison, S.C. | | Deposit date: | 2005-08-01 | | Release date: | 2005-09-20 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structure of SARS coronavirus spike receptor-binding domain complexed with receptor.
Science, 309, 2005
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2AZM
 | | Crystal structure of the MDC1 brct repeat in complex with the histone tail of gamma-H2AX | | Descriptor: | GAMMA-H2AX HISTONE, Mediator of DNA damage checkpoint protein 1 | | Authors: | Clapperton, J.A, Stucki, M, Mohammad, D, Yaffe, M.B, Jackson, S.P, Smerdon, S.J. | | Deposit date: | 2005-09-12 | | Release date: | 2006-01-31 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | MDC1 Directly Binds Phosphorylated Histone H2AX to Regulate Cellular Responses to DNA Double-Strand Breaks
Cell(Cambridge,Mass.), 123, 2005
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2BEL
 | | Structure of human 11-beta-hydroxysteroid dehydrogenase in complex with NADP and carbenoxolone | | Descriptor: | CARBENOXOLONE, CHLORIDE ION, CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 1, ... | | Authors: | Kavanagh, K, Wu, X, Svensson, S, Elleby, B, von Delft, F, Debreczeni, J.E, Sharma, S, Bray, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Abrahmsen, L, Oppermann, U. | | Deposit date: | 2004-11-25 | | Release date: | 2004-12-06 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.11 Å) | | Cite: | The High Resolution Structures of Human, Murine and Guinea Pig 11-Beta-Hydroxysteroid Dehydrogenase Type 1 Reveal Critical Differences in Active Site Architecture
To be Published
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2B6P
 | | X-ray structure of lens Aquaporin-0 (AQP0) (lens MIP) in an open pore state | | Descriptor: | Lens fiber major intrinsic protein | | Authors: | Gonen, T, Cheng, Y, Sliz, P, Hiroaki, Y, Fujiyoshi, Y, Harrison, S.C, Walz, T. | | Deposit date: | 2005-10-03 | | Release date: | 2005-12-06 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Lipid-protein interactions in double-layered two-dimensional AQP0 crystals.
Nature, 438, 2005
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2HGW
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3IDJ
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1XIW
 | | Crystal structure of human CD3-e/d dimer in complex with a UCHT1 single-chain antibody fragment | | Descriptor: | T-cell surface glycoprotein CD3 delta chain, T-cell surface glycoprotein CD3 epsilon chain, immunoglobulin heavy chain variable region, ... | | Authors: | Arnett, K.L, Harrison, S.C, Wiley, D.C. | | Deposit date: | 2004-09-22 | | Release date: | 2004-11-16 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of a human CD3-epsilon/delta dimer in complex with a UCHT1 single-chain antibody fragment.
Proc.Natl.Acad.Sci.USA, 101, 2004
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1JS9
 | | Brome Mosaic Virus | | Descriptor: | Coat protein, HEXAETHYLENE GLYCOL, MAGNESIUM ION | | Authors: | Lucas, R.W, Larson, S.B, McPherson, A. | | Deposit date: | 2001-08-16 | | Release date: | 2002-04-03 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | The crystallographic structure of brome mosaic virus.
J.Mol.Biol., 317, 2002
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1XX8
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3IDM
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1TFP
 | | TRANSTHYRETIN (FORMERLY KNOWN AS PREALBUMIN) | | Descriptor: | SULFATE ION, TRANSTHYRETIN | | Authors: | Sunde, M, Richardson, S.J, Chang, L, Pettersson, T.M, Schreiber, G, Blake, C.C.F. | | Deposit date: | 1996-01-05 | | Release date: | 1996-06-10 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | The crystal structure of transthyretin from chicken.
Eur.J.Biochem., 236, 1996
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3IDN
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4HKB
 | | CH67 Fab (unbound) from the CH65-67 Lineage | | Descriptor: | CH67 heavy chain, CH67 light chain | | Authors: | Schmidt, A.G, Harrison, S.C. | | Deposit date: | 2012-10-15 | | Release date: | 2012-11-21 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
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2I3T
 | | Bub3 complex with Mad3 (BubR1) GLEBS motif | | Descriptor: | Cell cycle arrest protein, Spindle assembly checkpoint component | | Authors: | Larsen, N.A, Harrison, S.C. | | Deposit date: | 2006-08-20 | | Release date: | 2007-01-09 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural analysis of Bub3 interactions in the mitotic spindle checkpoint.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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