1IGT

STRUCTURE OF IMMUNOGLOBULIN

Summary for 1IGT

DescriptorIGG2A INTACT ANTIBODY - MAB231, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywordsintact immunoglobulin v region c region, immunoglobulin
Biological sourceMus musculus (house mouse)
Total number of polymer chains4
Total molecular weight148682.04
Authors
Harris, L.J.,Larson, S.B.,Hasel, K.W.,McPherson, A. (deposition date: 1996-10-25, release date: 1997-07-07, Last modification date: 2020-07-29)
Primary citation
Harris, L.J.,Larson, S.B.,Hasel, K.W.,McPherson, A.
Refined structure of an intact IgG2a monoclonal antibody.
Biochemistry, 36:1581-1597, 1997
PubMed: 9048542 (PDB entries with the same primary citation)
DOI: 10.1021/bi962514+
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers21 3.7% 9.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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PDB entries from 2020-08-05