3MYU
 
 | | Mycoplasma genitalium MG289 | | Descriptor: | 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, ACETATE ION, High affinity transport system protein p37 | | Authors: | Sippel, K.H, Boehlein, S.K, Govindasamy, L, Namiki, K, Satai, Y, Quirit, J.G, Agbandje-McKenna, M, Goodison, S, Rosser, C.J, Sankaran, B, McKenna, R. | | Deposit date: | 2010-05-11 | | Release date: | 2010-10-20 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Insights into Mycoplasma genitalium metabolism revealed by the structure of MG289, an extracytoplasmic thiamine binding lipoprotein.
Proteins, 79, 2011
|
|
3N7N
 | | Structure of Csm1/Lrs4 complex | | Descriptor: | Monopolin complex subunit CSM1, Monopolin complex subunit LRS4 | | Authors: | Corbett, K.D, Harrison, S.C. | | Deposit date: | 2010-05-27 | | Release date: | 2010-09-01 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3.9 Å) | | Cite: | The Monopolin Complex Crosslinks Kinetochore Components to Regulate Chromosome-Microtubule Attachments.
Cell(Cambridge,Mass.), 142, 2010
|
|
3N4R
 | | Structure of Csm1 C-terminal domain, R3 form | | Descriptor: | MALONATE ION, Monopolin complex subunit CSM1, PENTAETHYLENE GLYCOL | | Authors: | Corbett, K.D, Harrison, S.C. | | Deposit date: | 2010-05-22 | | Release date: | 2010-09-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.602 Å) | | Cite: | The Monopolin Complex Crosslinks Kinetochore Components to Regulate Chromosome-Microtubule Attachments.
Cell(Cambridge,Mass.), 142, 2010
|
|
3N4X
 | | Structure of Csm1 full-length | | Descriptor: | Monopolin complex subunit CSM1 | | Authors: | Corbett, K.D, Harrison, S.C. | | Deposit date: | 2010-05-23 | | Release date: | 2010-09-01 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.408 Å) | | Cite: | The Monopolin Complex Crosslinks Kinetochore Components to Regulate Chromosome-Microtubule Attachments.
Cell(Cambridge,Mass.), 142, 2010
|
|
7SWO
 | | C98C7 Fab in complex with SARS-CoV-2 Spike 6P (RBD local reconstruction) | | Descriptor: | C98C7 Fab heavy chain, C98C7 Fab light chain, Spike protein S1 | | Authors: | Windsor, I.W, Tong, P, Wesemann, D.R, Harrison, S.C. | | Deposit date: | 2021-11-20 | | Release date: | 2022-04-27 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Antibodies induced by an ancestral SARS-CoV-2 strain that cross-neutralize variants from Alpha to Omicron BA.1.
Sci Immunol, 7, 2022
|
|
7SWP
 | | G32Q4 Fab in complex with SARS-CoV-2 Spike 6P (RBD local reconstruction) | | Descriptor: | G32Q4 Fab heavy chain, G32Q4 Fab light chain, Spike protein S1 | | Authors: | Windsor, I.W, Tong, P, Wesemann, D.R, Harrison, S.C. | | Deposit date: | 2021-11-20 | | Release date: | 2022-04-27 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Antibodies induced by an ancestral SARS-CoV-2 strain that cross-neutralize variants from Alpha to Omicron BA.1.
Sci Immunol, 7, 2022
|
|
7SWN
 | | G32A4 Fab in complex with SARS-CoV-2 Spike 6P (RBD local reconstruction) | | Descriptor: | G32A4 Fab heavy chain, G32A4 Fab light chain, Spike protein S1 | | Authors: | Windsor, I.W, Tong, P, Wesemann, D.R, Harrison, S.C. | | Deposit date: | 2021-11-20 | | Release date: | 2022-04-27 | | Last modified: | 2022-11-09 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Antibodies induced by an ancestral SARS-CoV-2 strain that cross-neutralize variants from Alpha to Omicron BA.1.
Sci Immunol, 7, 2022
|
|
7SXQ
 | | Plasmodium falciparum apicoplast DNA polymerase (exo-minus) without affinity tag | | Descriptor: | 1,2-ETHANEDIOL, Apicoplast DNA polymerase, CHLORIDE ION, ... | | Authors: | Nieto, N, Chheda, P, Kerns, R, Nelson, S, Honzatko, R. | | Deposit date: | 2021-11-24 | | Release date: | 2022-10-19 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Promising antimalarials targeting apicoplast DNA polymerase from Plasmodium falciparum.
Eur.J.Med.Chem., 243, 2022
|
|
7SXL
 | | Plasmodium falciparum apicoplast DNA polymerase (exo-minus) without affinity tag | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Nieto, N, Chheda, P, Kerns, R, Nelson, S, Honzatko, R. | | Deposit date: | 2021-11-23 | | Release date: | 2022-10-26 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Promising antimalarials targeting apicoplast DNA polymerase from Plasmodium falciparum.
Eur.J.Med.Chem., 243, 2022
|
|
6OUA
 | | Cryo-EM structure of the yeast Ctf3 complex | | Descriptor: | Inner kinetochore subunit CTF3, Inner kinetochore subunit MCM16, Inner kinetochore subunit MCM22 | | Authors: | Hinshaw, S.M, Harrison, S.C. | | Deposit date: | 2019-05-04 | | Release date: | 2019-05-15 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.18 Å) | | Cite: | The structure of the yeast Ctf3 complex.
Elife, 8, 2019
|
|
4XUC
 | | Synthesis and evaluation of heterocyclic catechol mimics as inhibitors of catechol-O-methyltransferase (COMT): Structure with Cmpd18 (1-(biphenyl-3-yl)-3-hydroxypyridin-4(1H)-one) | | Descriptor: | 1-(biphenyl-3-yl)-3-hydroxypyridin-4(1H)-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Catechol O-methyltransferase, ... | | Authors: | Allison, T, Wolkenberg, S, Sanders, J.M, Soisson, S.M. | | Deposit date: | 2015-01-25 | | Release date: | 2015-04-15 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Synthesis and Evaluation of Heterocyclic Catechol Mimics as Inhibitors of Catechol-O-methyltransferase (COMT).
Acs Med.Chem.Lett., 6, 2015
|
|
4XUD
 | | Synthesis and evaluation of heterocyclic catechol mimics as inhibitors of catechol-O-methyltransferase (COMT): Structure with Cmpd32 ([1-(biphenyl-3-yl)-5-hydroxy-4-oxo-1,4-dihydropyridin-3-yl]boronic acid) | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Catechol O-methyltransferase, MAGNESIUM ION, ... | | Authors: | Allison, T, Wolkenberg, S, Sanders, J.M, Soisson, S.M. | | Deposit date: | 2015-01-25 | | Release date: | 2015-04-15 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Synthesis and Evaluation of Heterocyclic Catechol Mimics as Inhibitors of Catechol-O-methyltransferase (COMT).
Acs Med.Chem.Lett., 6, 2015
|
|
4XUE
 | | Synthesis and evaluation of heterocyclic catechol mimics as inhibitors of catechol-O-methyltransferase (COMT): Structure with Cmpd27b | | Descriptor: | 2-(biphenyl-3-yl)-5-hydroxy-3-methylpyrimidin-4(3H)-one, Catechol O-methyltransferase, MAGNESIUM ION, ... | | Authors: | Allison, T, Wolkenberg, S, Sanders, J.M, Soisson, S.M. | | Deposit date: | 2015-01-25 | | Release date: | 2015-04-15 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Synthesis and Evaluation of Heterocyclic Catechol Mimics as Inhibitors of Catechol-O-methyltransferase (COMT).
Acs Med.Chem.Lett., 6, 2015
|
|
7TEO
 | | Cryo-EM structure of the 20S Alpha 3 Deletion proteasome core particle in complex with FUB1 | | Descriptor: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, ... | | Authors: | Walsh Jr, R.M, Rawson, S, Schnell, H.M, Hanna, J. | | Deposit date: | 2022-01-05 | | Release date: | 2022-08-10 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (2.97 Å) | | Cite: | Yeast PI31 inhibits the proteasome by a direct multisite mechanism.
Nat.Struct.Mol.Biol., 29, 2022
|
|
7TEJ
 | | Cryo-EM structure of the 20S Alpha 3 Deletion proteasome core particle | | Descriptor: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-4, ... | | Authors: | Walsh Jr, R.M, Rawson, S, Schnell, H.M, Hanna, J. | | Deposit date: | 2022-01-05 | | Release date: | 2022-08-10 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (2.74 Å) | | Cite: | Yeast PI31 inhibits the proteasome by a direct multisite mechanism.
Nat.Struct.Mol.Biol., 29, 2022
|
|
6PPE
 | | ClpP and ClpX IGF loop in ClpX-ClpP complex with D7 symmetry | | Descriptor: | ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit | | Authors: | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | | Deposit date: | 2019-07-06 | | Release date: | 2020-03-11 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.19 Å) | | Cite: | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate.
Elife, 9, 2020
|
|
4Z6B
 | | YopH W354H Yersinia enterocolitica PTPase in the apo form | | Descriptor: | ACETATE ION, GLYCEROL, Tyrosine-protein phosphatase YopH | | Authors: | Moise, G.E, Johnson, S.J, Hengge, A.C. | | Deposit date: | 2015-04-04 | | Release date: | 2015-10-28 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Conservative Tryptophan Mutants of the Protein Tyrosine Phosphatase YopH Exhibit Impaired WPD-Loop Function and Crystallize with Divanadate Esters in Their Active Sites.
Biochemistry, 54, 2015
|
|
7AMY
 | |
6YSF
 | |
8ASG
 | | Structure of the SFTSV L protein bound in a resting state [RESTING] | | Descriptor: | MAGNESIUM ION, RNA (5'-R(*AP*CP*AP*CP*AP*GP*AP*GP*AP*CP*GP*CP*CP*CP*AP*GP*AP*UP*GP*A*)-3'), RNA (5'-R(*GP*AP*UP*CP*UP*GP*GP*GP*CP*GP*GP*UP*CP*UP*UP*UP*GP*UP*GP*U*)-3'), ... | | Authors: | Williams, H.M, Thorkelsson, S.R, Vogel, D, Milewski, M, Busch, C, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M. | | Deposit date: | 2022-08-19 | | Release date: | 2023-01-18 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein.
Nucleic Acids Res., 51, 2023
|
|
7ALK
 | | Structure of Drosophila C2-DSL-EGF1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Neurogenic locus protein delta, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Suckling, R, Johnson, S, Lea, S.M. | | Deposit date: | 2020-10-06 | | Release date: | 2021-08-04 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The conserved C2 phospholipid-binding domain in Delta contributes to robust Notch signalling.
Embo Rep., 22, 2021
|
|
7ALJ
 | | Structure of Drosophila Notch EGF domains 11-13 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neurogenic locus Notch protein, ... | | Authors: | Suckling, R, Johnson, S, Lea, S.M. | | Deposit date: | 2020-10-06 | | Release date: | 2021-08-04 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.52 Å) | | Cite: | The conserved C2 phospholipid-binding domain in Delta contributes to robust Notch signalling.
Embo Rep., 22, 2021
|
|
8AS6
 | | Structure of the SFTSV L protein bound to 5' cRNA hook [5' HOOK] | | Descriptor: | RNA (5'-R(*AP*CP*AP*CP*AP*GP*AP*GP*AP*CP*GP*CP*CP*C)-3'), RNA-dependent RNA-polymerase L protein | | Authors: | Williams, H.M, Thorkelsson, S.R, Vogel, D, Milewski, M, Busch, C, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M. | | Deposit date: | 2022-08-18 | | Release date: | 2023-01-18 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein.
Nucleic Acids Res., 51, 2023
|
|
7ALT
 | | Structure of Drosophila Serrate C2-DSL-EGF1-EGF2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Suckling, R, Johnson, S, Lea, S.M. | | Deposit date: | 2020-10-07 | | Release date: | 2021-08-04 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | The conserved C2 phospholipid-binding domain in Delta contributes to robust Notch signalling.
Embo Rep., 22, 2021
|
|
6Q0J
 | | Structure of a MAPK pathway complex | | Descriptor: | 14-3-3 protein zeta, 5-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide, Dual specificity mitogen-activated protein kinase kinase 1, ... | | Authors: | Park, E, Rawson, S, Jeon, H, Eck, M.J. | | Deposit date: | 2019-08-01 | | Release date: | 2019-10-09 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (4.9 Å) | | Cite: | Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes.
Nature, 575, 2019
|
|
