3MYU
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![BU of 3myu by Molmil](/molmil-images/mine/3myu) | Mycoplasma genitalium MG289 | Descriptor: | 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, ACETATE ION, High affinity transport system protein p37 | Authors: | Sippel, K.H, Boehlein, S.K, Govindasamy, L, Namiki, K, Satai, Y, Quirit, J.G, Agbandje-McKenna, M, Goodison, S, Rosser, C.J, Sankaran, B, McKenna, R. | Deposit date: | 2010-05-11 | Release date: | 2010-10-20 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Insights into Mycoplasma genitalium metabolism revealed by the structure of MG289, an extracytoplasmic thiamine binding lipoprotein. Proteins, 79, 2011
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3MNV
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![BU of 3mnv by Molmil](/molmil-images/mine/3mnv) | Crystal structure of the non-neutralizing HIV antibody 13H11 Fab fragment | Descriptor: | 1,2-ETHANEDIOL, ANTI-HIV-1 ANTIBODY 13H11 HEAVY CHAIN, ANTI-HIV-1 ANTIBODY 13H11 LIGHT CHAIN, ... | Authors: | Nicely, N.I, Dennison, S.M, Kelsoe, G, Liao, H.-X, Alam, S.M, Haynes, B.F. | Deposit date: | 2010-04-22 | Release date: | 2010-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of a non-neutralizing antibody to the HIV-1 gp41 membrane-proximal external region. Nat.Struct.Mol.Biol., 17, 2010
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1T1B
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![BU of 1t1b by Molmil](/molmil-images/mine/1t1b) | Late intermediate IL2 from time-resolved crystallography of the E46Q mutant of PYP | Descriptor: | 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein | Authors: | Rajagopal, S, Anderson, S, Srajer, V, Schmidt, M, Pahl, R, Moffat, K. | Deposit date: | 2004-04-15 | Release date: | 2005-01-18 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A Structural Pathway for Signaling in the E46Q Mutant of Photoactive Yellow Protein Structure, 13, 2005
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4Q0C
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![BU of 4q0c by Molmil](/molmil-images/mine/4q0c) | 3.1 A resolution crystal structure of the B. pertussis BvgS periplasmic domain | Descriptor: | Virulence sensor protein BvgS | Authors: | Dupre, E, Herrou, J, Lensink, M.F, Wintjens, R, Lebedev, A, Crosson, S, Villeret, V, Locht, C, Antoine, R, Jacob-Dubuisson, F. | Deposit date: | 2014-04-01 | Release date: | 2015-02-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Virulence Regulation with Venus Flytrap Domains: Structure and Function of the Periplasmic Moiety of the Sensor-Kinase BvgS. Plos Pathog., 11, 2015
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1T1C
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![BU of 1t1c by Molmil](/molmil-images/mine/1t1c) | Late intermediate IL3 from time-resolved crystallography of the E46Q mutant of PYP | Descriptor: | 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein | Authors: | Rajagopal, S, Anderson, S, Srajer, V, Schmidt, M, Pahl, R, Moffat, K. | Deposit date: | 2004-04-15 | Release date: | 2005-01-18 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A Structural Pathway for Signaling in the E46Q Mutant of Photoactive Yellow Protein Structure, 13, 2005
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2XXI
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![BU of 2xxi by Molmil](/molmil-images/mine/2xxi) | Crystal structure of 1-((4-(3-(trifluoromethyl)-6,7-dihydropyrano(4,3- c(pyrazol-1(4H)-yl)phenyl)methyl)-2-pyrrolidinone in complex with the ligand binding domain of the Rat GluA2 receptor and glutamate at 1.6A resolution. | Descriptor: | 1-({4-[3-(TRIFLUOROMETHYL)-6,7-DIHYDROPYRANO[4,3-C]PYRAZOL-1(4H)-YL]PHENYL}METHYL)-2-PYRROLIDINONE, GLUTAMATE RECEPTOR 2, GLUTAMIC ACID, ... | Authors: | Ward, S.E, Harries, M, Aldegheri, L, Austin, N.E, Ballantine, S, Ballini, E, Bradley, D.M, Bax, B.D, Clarke, B.P, Harris, A.J, Harrison, S.A, Melarange, R.A, Mookherjee, C, Mosley, J, DalNegro, G, Oliosi, B, Smith, K.J, Thewlis, K.M, Woollard, P.M, Yusaf, S.P. | Deposit date: | 2010-11-10 | Release date: | 2011-04-06 | Last modified: | 2011-09-28 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Integration of Lead Optimization with Crystallography for a Membrane-Bound Ion Channel Target: Discovery of a New Class of Ampa Receptor Positive Allosteric Modulators. J.Med.Chem., 54, 2011
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4GXI
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![BU of 4gxi by Molmil](/molmil-images/mine/4gxi) | R283K DNA polymerase beta binary complex with a templating 8OG | Descriptor: | DNA (5'-D(*CP*CP*GP*AP*CP*(8OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... | Authors: | Freudenthal, B.D, Beard, W.A, Wilson, S.H. | Deposit date: | 2012-09-04 | Release date: | 2013-01-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.949 Å) | Cite: | DNA polymerase minor groove interactions modulate mutagenic bypass of a templating 8-oxoguanine lesion. Nucleic Acids Res., 41, 2013
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3N4X
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![BU of 3n4x by Molmil](/molmil-images/mine/3n4x) | Structure of Csm1 full-length | Descriptor: | Monopolin complex subunit CSM1 | Authors: | Corbett, K.D, Harrison, S.C. | Deposit date: | 2010-05-23 | Release date: | 2010-09-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.408 Å) | Cite: | The Monopolin Complex Crosslinks Kinetochore Components to Regulate Chromosome-Microtubule Attachments. Cell(Cambridge,Mass.), 142, 2010
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3N4S
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![BU of 3n4s by Molmil](/molmil-images/mine/3n4s) | Structure of Csm1 C-terminal domain, P21212 form | Descriptor: | Monopolin complex subunit CSM1, PENTAETHYLENE GLYCOL | Authors: | Corbett, K.D, Harrison, S.C. | Deposit date: | 2010-05-22 | Release date: | 2010-09-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | The Monopolin Complex Crosslinks Kinetochore Components to Regulate Chromosome-Microtubule Attachments. Cell(Cambridge,Mass.), 142, 2010
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6DE8
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![BU of 6de8 by Molmil](/molmil-images/mine/6de8) | Crystal Structure of Bifunctional Enzyme FolD-Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase from Campylobacter jejuni | Descriptor: | Bifunctional protein FolD, CHLORIDE ION, GLYCEROL, ... | Authors: | Kim, Y, Makowska-Grzyska, M, Zhang, R, Peterson, S.N, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2018-05-11 | Release date: | 2018-05-30 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (2.104 Å) | Cite: | Crystal Structure of Bifunctional Enzyme FolD-Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase from Campylobacter jejuni To Be Published
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3TFS
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![BU of 3tfs by Molmil](/molmil-images/mine/3tfs) | Ternary complex structure of DNA polymerase beta with a gapped DNA substrate and a, b dAMP(CFH)PP in the active site: Stereoselective binding of (S) isomer | Descriptor: | 2'-deoxy-5'-O-[(S)-{(S)-fluoro[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}(hydroxy)phosphoryl]adenosine, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*TP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... | Authors: | Chamberlain, B.T, Batra, V.K, Beard, W.A, Kadina, A.P, Shock, D.D, Kashemirov, B.A, McKenna, C.E, Goodman, M.F, Wilson, S.H. | Deposit date: | 2011-08-16 | Release date: | 2012-03-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Stereospecific Formation of a Ternary Complex of (S)-alpha, beta-Fluoromethylene-dATP with DNA Pol beta. Chembiochem, 13, 2012
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3N7N
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![BU of 3n7n by Molmil](/molmil-images/mine/3n7n) | Structure of Csm1/Lrs4 complex | Descriptor: | Monopolin complex subunit CSM1, Monopolin complex subunit LRS4 | Authors: | Corbett, K.D, Harrison, S.C. | Deposit date: | 2010-05-27 | Release date: | 2010-09-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | The Monopolin Complex Crosslinks Kinetochore Components to Regulate Chromosome-Microtubule Attachments. Cell(Cambridge,Mass.), 142, 2010
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3N4R
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![BU of 3n4r by Molmil](/molmil-images/mine/3n4r) | Structure of Csm1 C-terminal domain, R3 form | Descriptor: | MALONATE ION, Monopolin complex subunit CSM1, PENTAETHYLENE GLYCOL | Authors: | Corbett, K.D, Harrison, S.C. | Deposit date: | 2010-05-22 | Release date: | 2010-09-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.602 Å) | Cite: | The Monopolin Complex Crosslinks Kinetochore Components to Regulate Chromosome-Microtubule Attachments. Cell(Cambridge,Mass.), 142, 2010
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1T18
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![BU of 1t18 by Molmil](/molmil-images/mine/1t18) | Early intermediate IE1 from time-resolved crystallography of the E46Q mutant of PYP | Descriptor: | 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein | Authors: | Rajagopal, S, Anderson, S, Srajer, V, Schmidt, M, Pahl, R, Moffat, K. | Deposit date: | 2004-04-15 | Release date: | 2005-01-18 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A Structural Pathway for Signaling in the E46Q Mutant of Photoactive Yellow Protein Structure, 13, 2005
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3C45
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![BU of 3c45 by Molmil](/molmil-images/mine/3c45) | Human dipeptidyl peptidase IV/CD26 in complex with a fluoroolefin inhibitor | Descriptor: | (2S,3S)-3-{3-[2-chloro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-cyclopentylidene-4-cyclopropyl-1-fluorobutan-2-amine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Scapin, G, Edmondson, S.D, Weber, A.E. | Deposit date: | 2008-01-29 | Release date: | 2008-04-22 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Fluoroolefins as amide bond mimics in dipeptidyl peptidase IV inhibitors Bioorg.Med.Chem.Lett., 18, 2008
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3ECT
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![BU of 3ect by Molmil](/molmil-images/mine/3ect) | Crystal Structure of the Hexapeptide-Repeat Containing-Acetyltransferase VCA0836 from Vibrio cholerae | Descriptor: | CALCIUM ION, Hexapeptide-repeat containing-acetyltransferase | Authors: | Kim, Y, Maltseva, N, Kwon, K, Papazisi, L, Hasseman, J, Peterson, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2008-09-02 | Release date: | 2008-09-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Crystal Structure of the Hexapeptide-Repeat Containing-Acetyltransferase VCA0836 from Vibrio cholerae To be Published
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2R32
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![BU of 2r32 by Molmil](/molmil-images/mine/2r32) | Crystal Structure of human GITRL variant | Descriptor: | GCN4-pII/Tumor necrosis factor ligand superfamily member 18 fusion protein, SULFATE ION | Authors: | Chattopadhyay, K, Ramagopal, U.A, Nathenson, S.G, Almo, S.C. | Deposit date: | 2007-08-28 | Release date: | 2007-11-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function. Proc.Natl.Acad.Sci.USA, 104, 2007
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4DXD
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![BU of 4dxd by Molmil](/molmil-images/mine/4dxd) | Staphylococcal Aureus FtsZ in complex with 723 | Descriptor: | 3-[(6-chloro[1,3]thiazolo[5,4-b]pyridin-2-yl)methoxy]-2,6-difluorobenzamide, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE | Authors: | Lu, J, Soisson, S.M. | Deposit date: | 2012-02-27 | Release date: | 2012-05-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Restoring methicillin-resistant Staphylococcus aureus susceptibility to beta-lactam antibiotics. Sci Transl Med, 4, 2012
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4GFJ
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![BU of 4gfj by Molmil](/molmil-images/mine/4gfj) | Crystal structure of Topo-78, an N-terminal 78kDa fragment of topoisomerase V | Descriptor: | GLYCEROL, Topoisomerase V, ZINC ION | Authors: | Rajan, R, Prasad, R, Taneja, B, Wilson, S.H, Mondragon, A. | Deposit date: | 2012-08-03 | Release date: | 2012-12-05 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | Identification of one of the apurinic/apyrimidinic lyase active sites of topoisomerase V by structural and functional studies. Nucleic Acids Res., 41, 2013
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1T19
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![BU of 1t19 by Molmil](/molmil-images/mine/1t19) | Early intermediate IE2 from time-resolved crystallography of the E46Q mutant of PYP | Descriptor: | 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein | Authors: | Rajagopal, S, Anderson, S, Srajer, V, Schmidt, M, Pahl, R, Moffat, K. | Deposit date: | 2004-04-15 | Release date: | 2005-01-18 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A Structural Pathway for Signaling in the E46Q Mutant of Photoactive Yellow Protein Structure, 13, 2005
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1T1A
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![BU of 1t1a by Molmil](/molmil-images/mine/1t1a) | Late intermediate IL1 from time-resolved crystallography of the E46Q mutant of PYP | Descriptor: | 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein | Authors: | Rajagopal, S, Anderson, S, Srajer, V, Schmidt, M, Pahl, R, Moffat, K. | Deposit date: | 2004-04-15 | Release date: | 2005-01-18 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A Structural Pathway for Signaling in the E46Q Mutant of Photoactive Yellow Protein Structure, 13, 2005
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2CA5
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![BU of 2ca5 by Molmil](/molmil-images/mine/2ca5) | MxiH needle protein of Shigella Flexneri (monomeric form, residues 1- 78) | Descriptor: | GLYCEROL, ISOPROPYL ALCOHOL, MXIH, ... | Authors: | Deane, J.E, Roversi, P, Cordes, F.S, Johnson, S, Kenjale, R, Picking, W.L, Picking, W.D, Blocker, A.J, Lea, S.M. | Deposit date: | 2005-12-16 | Release date: | 2006-08-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Molecular Model of a Type III Secretion System Needle: Implications for Host-Cell Sensing Proc.Natl.Acad.Sci.USA, 103, 2006
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3K1O
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![BU of 3k1o by Molmil](/molmil-images/mine/3k1o) | Crystal structure of sterol 14-alpha demethylase (CYP51) from Trypanosoma cruzi in complex with a potential antichagasic drug, posaconazole | Descriptor: | 2,5-anhydro-1,3,4-trideoxy-2-(2,4-difluorophenyl)-6-O-{4-[4-(4-{1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl}phenyl)piperazin-1-yl]phenyl}-1-(1H-1,2,4-triazol-1-yl)-D-erythro-hexitol, PROTOPORPHYRIN IX CONTAINING FE, Sterol 14 alpha-demethylase | Authors: | Lepesheva, G.I, Hargrove, T.Y, Anderson, S, Wawrzak, Z, Waterman, M.R. | Deposit date: | 2009-09-28 | Release date: | 2009-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Structural Insights into Inhibition of Sterol 14{alpha}-Demethylase in the Human Pathogen Trypanosoma cruzi. J.Biol.Chem., 285, 2010
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8CQO
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![BU of 8cqo by Molmil](/molmil-images/mine/8cqo) | Crystal structure of Borrelia burgdorferi paralogous family 12 outer surface protein BBK01 (Se-Met data) | Descriptor: | Lipoprotein, putative | Authors: | Brangulis, K, Drunka, L, Matisone, S, Akopjana, I, Tars, K. | Deposit date: | 2023-03-06 | Release date: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Crystal structure of Borrelia burgdorferi outer surface protein BBK01 To Be Published
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5TZR
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![BU of 5tzr by Molmil](/molmil-images/mine/5tzr) | GPR40 in complex with partial agonist MK-8666 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (5aR,6S,6aS)-3-({2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl}methoxy)-5,5a,6,6a-tetrahydrocyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylic acid, Free fatty acid receptor 1,Endolysin,Free fatty acid receptor 1, ... | Authors: | Lu, J, Byrne, N, Patel, S, Sharma, S, Soisson, S.M. | Deposit date: | 2016-11-22 | Release date: | 2017-06-07 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40. Nat. Struct. Mol. Biol., 24, 2017
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