5Z6U
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5E64
| Hemagglutinin-esterase-fusion protein structure of influenza D virus | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CACODYLATE ION, ... | Authors: | Song, H, Qi, J, Shi, Y, Gao, G.F. | Deposit date: | 2015-10-09 | Release date: | 2016-03-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | An Open Receptor-Binding Cavity of Hemagglutinin-Esterase-Fusion Glycoprotein from Newly-Identified Influenza D Virus: Basis for Its Broad Cell Tropism PLoS Pathog., 12, 2016
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1M4Y
| Crystal structure of HslV from Thermotoga maritima | Descriptor: | ATP-dependent protease hslV, SODIUM ION | Authors: | Song, H.K, Ramachandran, R, Bochtler, M.B, Hartmann, C, Azim, M.K, Huber, R. | Deposit date: | 2002-07-05 | Release date: | 2003-05-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Isolation and characterization of the prokaryotic proteasome homolog HslVU (ClpQY) from Thermotoga maritima and the crystal structure of HslV. BIOPHYS.CHEM., 100, 2003
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3BSF
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5HXX
| Crystal structure of AspAT from Corynebacterium glutamicum | Descriptor: | 2-OXOGLUTARIC ACID, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ASPARTATE AMINOTRANSFERASE, ... | Authors: | Son, H.-F, Kim, K.-J. | Deposit date: | 2016-01-31 | Release date: | 2016-02-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural insights into a novel class of aspartate aminotransferase from Corynebacterium glutamicum To be published
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9C1R
| Crystal structure of mutant cMET D1228N kinase domain in complex with inhibitor compound 13 | Descriptor: | GLYCEROL, Hepatocyte growth factor receptor, N-(2,5-difluoro-4-{[(1s,3S)-3-(1-methyl-1H-pyrazol-3-yl)cyclobutyl][(8R)-pyrazolo[1,5-a]pyrazin-4-yl]amino}phenyl)-2-(5-fluoropyridin-2-yl)-3-oxo-2,3-dihydropyridazine-4-carboxamide | Authors: | Simpson, H, Wu, W.-I, Mou, T.-C. | Deposit date: | 2024-05-29 | Release date: | 2024-08-21 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Discovery of Pyrazolopyrazines as Selective, Potent, and Mutant-Active MET Inhibitors with Intracranial Efficacy. J.Med.Chem., 67, 2024
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4URP
| The Crystal structure of Nitroreductase from Saccharomyces cerevisiae | Descriptor: | FATTY ACID REPRESSION MUTANT PROTEIN 2 | Authors: | Song, H.-N, Woo, E.-J, Bang, S.-Y, Jung, D.-G, Park, S.-G. | Deposit date: | 2014-07-01 | Release date: | 2015-04-29 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.991 Å) | Cite: | Crystal Structure of the Fungal Nitroreductase Frm2 from Saccharomyces Cerevisiae. Protein Sci., 24, 2015
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6JO8
| The complex structure of CHIKV envelope glycoprotein bound to human MXRA8 | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHIKV E1, ... | Authors: | Song, H, Zhao, Z, Qi, J, Gao, F, Gao, F.G. | Deposit date: | 2019-03-20 | Release date: | 2019-05-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.495 Å) | Cite: | Molecular Basis of Arthritogenic Alphavirus Receptor MXRA8 Binding to Chikungunya Virus Envelope Protein. Cell, 177, 2019
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6JO7
| Crystal structure of mouse MXRA8 | Descriptor: | Matrix remodeling-associated protein 8 | Authors: | Song, H, Zhao, Z, Qi, J, Gao, F, Gao, G.F. | Deposit date: | 2019-03-20 | Release date: | 2019-05-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular Basis of Arthritogenic Alphavirus Receptor MXRA8 Binding to Chikungunya Virus Envelope Protein. Cell, 177, 2019
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6K7O
| Complex structure of LILRB4 and h128-3 antibody | Descriptor: | Leukocyte immunoglobulin-like receptor subfamily B member 4, h128-3 Fab heavy chain, h128-3 Fab light chain | Authors: | Song, H, Chai, Y, Xu, X, Gao, F.G. | Deposit date: | 2019-06-08 | Release date: | 2019-07-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.004 Å) | Cite: | Disrupting LILRB4/APOE Interaction by an Efficacious Humanized Antibody Reverses T-cell Suppression and Blocks AML Development. Cancer Immunol Res, 7, 2019
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5N4I
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7BSD
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5N0X
| Crystal structure of OphA-DeltaC6 in complex with SAM | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, Peptide N-Methyltransferase, ... | Authors: | Song, H, Naismith, J.H. | Deposit date: | 2017-02-03 | Release date: | 2018-02-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | A molecular mechanism for the enzymatic methylation of nitrogen atoms within peptide bonds. Sci Adv, 4, 2018
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5N0S
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5N0R
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6QZY
| full length OphA V406P in complex with SAH | Descriptor: | ASN-GLY-PHE-PRO-TRP-MVA-ILE-MVA-VAL-GLY-PRO-ILE-GLY, MAGNESIUM ION, Peptide N-methyltransferase, ... | Authors: | Song, H, Naismith, J.H. | Deposit date: | 2019-03-12 | Release date: | 2020-04-01 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Substrate Plasticity of a Fungal Peptide alpha-N-Methyltransferase. Acs Chem.Biol., 15, 2020
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6QZZ
| full length OphA V404E in complex with SAH | Descriptor: | Peptide N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Song, H, Naismith, J.H. | Deposit date: | 2019-03-12 | Release date: | 2020-04-01 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Substrate Plasticity of a Fungal Peptide alpha-N-Methyltransferase. Acs Chem.Biol., 15, 2020
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6R00
| OphA DeltaC6 V404F complex with SAH | Descriptor: | PHE-PRO-TRP-MVA-ILE-MVA-PHE-GLY-VAL-ILE-GLY-VAL-ILE-GLY, Peptide N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Song, H, Naismith, J.H. | Deposit date: | 2019-03-12 | Release date: | 2020-04-01 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Substrate Plasticity of a Fungal Peptide alpha-N-Methyltransferase. Acs Chem.Biol., 15, 2020
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7ZAZ
| macrocyclase OphP with ZPP | Descriptor: | 1,2-ETHANEDIOL, BICARBONATE ION, DIMETHYL SULFOXIDE, ... | Authors: | Song, H, Naismith, J.H. | Deposit date: | 2022-03-23 | Release date: | 2022-07-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular basis for the enzymatic macrocyclization of multiply backbone N-methylated peptides Biorxiv, 2022
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7ZB2
| apo macrocyclase OphP | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | Authors: | Song, H, Naismith, J.H. | Deposit date: | 2022-03-23 | Release date: | 2022-07-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Molecular basis for the enzymatic macrocyclization of multiply backbone N-methylated peptides Biorxiv, 2022
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5N0V
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5N0W
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5N0N
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5N0U
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5N0T
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