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PDB: 165 件
7LZ2
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BU of 7lz2 by Molmil
Structure of glutamate receptor-like channel GLR3.4 ligand-binding domain in complex with methionine
分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, GLYCEROL, ...
著者Gangwar, S.P, Green, M.N, Sobolevsky, A.I.
登録日2021-03-08
公開日2021-07-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4.
Mol.Cell, 81, 2021
7LZI
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Structure of the glutamate receptor-like channel AtGLR3.4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, Glutamate receptor 3.4
著者Gangwar, S.P, Green, M.N, Sobolevsky, A.I.
登録日2021-03-09
公開日2021-07-28
最終更新日2021-08-18
実験手法ELECTRON MICROSCOPY (4.39 Å)
主引用文献Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4.
Mol.Cell, 81, 2021
7LZH
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Structure of the glutamate receptor-like channel AtGLR3.4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
著者Gangwar, S.P, Green, M.N, Sobolevsky, A.I.
登録日2021-03-09
公開日2021-07-28
最終更新日2021-08-18
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4.
Mol.Cell, 81, 2021
7LZ1
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BU of 7lz1 by Molmil
Structure of glutamate receptor-like channel GLR3.4 ligand-binding domain in complex with serine
分子名称: GLYCEROL, Glutamate receptor 3.4, SERINE, ...
著者Gangwar, S.P, Green, M.N, Sobolevsky, A.I.
登録日2021-03-08
公開日2021-07-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4.
Mol.Cell, 81, 2021
7LZ0
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BU of 7lz0 by Molmil
Structure of glutamate receptor-like channel GLR3.4 ligand-binding domain in complex with glutamate
分子名称: CHLORIDE ION, GLUTAMIC ACID, GLYCEROL, ...
著者Gangwar, S.P, Green, M.N, Sobolevsky, A.I.
登録日2021-03-08
公開日2021-07-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4.
Mol.Cell, 81, 2021
7MIO
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BU of 7mio by Molmil
Mouse TRPV3 in cNW11 nanodiscs, open state at 42 degrees Celsius
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3
著者Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I.
登録日2021-04-17
公開日2021-07-21
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel.
Nat.Struct.Mol.Biol., 28, 2021
7MIJ
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BU of 7mij by Molmil
Mouse TRPV3 in MSP2N2 nanodiscs, closed state at 4 degrees Celsius
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3
著者Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I.
登録日2021-04-17
公開日2021-07-21
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (1.98 Å)
主引用文献Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel.
Nat.Struct.Mol.Biol., 28, 2021
7MIK
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BU of 7mik by Molmil
Mouse TRPV3 in MSP2N2 nanodiscs, closed state at 42 degrees Celsius
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3
著者Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I.
登録日2021-04-17
公開日2021-07-21
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel.
Nat.Struct.Mol.Biol., 28, 2021
7MIL
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Mouse TRPV3 in MSP2N2 nanodiscs, sensitized state at 42 degrees Celsius
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3
著者Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I.
登録日2021-04-17
公開日2021-07-21
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (3.86 Å)
主引用文献Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel.
Nat.Struct.Mol.Biol., 28, 2021
7MIN
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BU of 7min by Molmil
Mouse TRPV3 in cNW11 nanodiscs, closed state at 42 degrees Celsius
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3
著者Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I.
登録日2021-04-17
公開日2021-07-21
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel.
Nat.Struct.Mol.Biol., 28, 2021
7MIM
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BU of 7mim by Molmil
Mouse TRPV3 in cNW11 nanodiscs, closed state at 4 degrees Celsius
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3
著者Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I.
登録日2021-04-17
公開日2021-07-21
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel.
Nat.Struct.Mol.Biol., 28, 2021
7K4B
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BU of 7k4b by Molmil
Cryo-EM structure of human TRPV6 in complex with (4- phenylcyclohexyl)piperazine inhibitor cis-22a
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[cis-4-(3-methylphenyl)cyclohexyl]-4-(pyridin-3-yl)piperazine, CALCIUM ION, ...
著者Neuberger, A, Nadezhdin, K.D, Singh, A.K, Sobolevsky, A.I.
登録日2020-09-15
公開日2020-12-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Inactivation-mimicking block of the epithelial calcium channel TRPV6.
Sci Adv, 6, 2020
7K4C
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Cryo-EM structure of human TRPV6 in complex with (4- phenylcyclohexyl)piperazine inhibitor Br-cis-22a
分子名称: 1-(5-bromopyridin-3-yl)-4-[cis-4-(3-methylphenyl)cyclohexyl]piperazine, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6
著者Neuberger, A, Nadezhdin, K.D, Singh, A.K, Sobolevsky, A.I.
登録日2020-09-15
公開日2020-12-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.78 Å)
主引用文献Inactivation-mimicking block of the epithelial calcium channel TRPV6.
Sci Adv, 6, 2020
7K4A
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BU of 7k4a by Molmil
Cryo-EM structure of human TRPV6 in the open state
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ...
著者Neuberger, A, Nadezhdin, K.D, Singh, A.K, Sobolevsky, A.I.
登録日2020-09-15
公開日2020-12-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Inactivation-mimicking block of the epithelial calcium channel TRPV6.
Sci Adv, 6, 2020
7TNK
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BU of 7tnk by Molmil
Complex GNNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNO
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BU of 7tno by Molmil
Complex GGGN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (4.02 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNM
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BU of 7tnm by Molmil
Complex GNGN2 of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (4.74 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNL
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BU of 7tnl by Molmil
Complex GNGN1 of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNN
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BU of 7tnn by Molmil
Complex GGNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNJ
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BU of 7tnj by Molmil
Complex NNNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (4.02 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNP
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BU of 7tnp by Molmil
Complex GGGG of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (3.96 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7LQY
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Structure of squirrel TRPV1 in apo state
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoinositol, CHLORIDE ION, ...
著者Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I.
登録日2021-02-15
公開日2021-04-21
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.19 Å)
主引用文献Extracellular cap domain is an essential component of the TRPV1 gating mechanism.
Nat Commun, 12, 2021
7LQZ
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Structure of squirrel TRPV1 in complex with RTX
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Osm-9-like TRP channel 1, SODIUM ION, ...
著者Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I.
登録日2021-02-15
公開日2021-04-21
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Extracellular cap domain is an essential component of the TRPV1 gating mechanism.
Nat Commun, 12, 2021
6D7Q
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Crystal Structure of Rat TRPV6*-Y466A in complex with 2-Aminoethoxydiphenyl borate (2-APB)
分子名称: 2-aminoethyl diphenylborinate, 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, ...
著者Singh, A.K, Saotome, K, McGoldrick, L.L, Sobolevsky, A.I.
登録日2018-04-25
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.497 Å)
主引用文献Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB.
Nat Commun, 9, 2018
6D7X
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BU of 6d7x by Molmil
Crystal Structure of Rat TRPV6*-Y466A- in complex with brominated 2-Aminoethoxydiphenyl borate (2-APB-Br)
分子名称: 2-aminoethyl (4-bromophenyl)phenylborinate, 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, ...
著者Singh, A.K, Saotome, K, McGoldrick, L.L, Sobolevsky, A.I.
登録日2018-04-25
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB.
Nat Commun, 9, 2018

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