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PDB: 165 件

3KG2
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AMPA subtype ionotropic glutamate receptor in complex with competitive antagonist ZK 200775
分子名称: Glutamate receptor 2, beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Sobolevsky, A.I, Rosconi, M.P, Gouaux, E.
登録日2009-10-28
公開日2009-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor.
Nature, 462, 2009
3KGC
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Isolated ligand binding domain dimer of GluA2 ionotropic glutamate receptor in complex with glutamate, LY 404187 and ZK 200775
分子名称: GLUTAMIC ACID, Glutamate receptor 2, N-[(2S)-2-(4'-cyanobiphenyl-4-yl)propyl]propane-2-sulfonamide, ...
著者Sobolevsky, A.I, Rosconi, M.P, Gouaux, E.
登録日2009-10-28
公開日2009-12-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor
Nature, 462, 2009
1ZNU
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Structure of cyclotide Kalata B1 in DPC micelles solution
分子名称: Kalata B1
著者Shenkarev, Z.O, Nadezhdin, K.D, Sobol, V.A, Sobol, A.G, Skjeldal, L, Arseniev, A.S.
登録日2005-05-12
公開日2006-04-25
最終更新日2020-02-05
実験手法SOLUTION NMR
主引用文献Conformation and mode of membrane interaction in cyclotides. Spatial structure of kalata B1 bound to a dodecylphosphocholine micelle.
Febs J., 273, 2006
1ECI
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ECTATOMIN (WATER SOLUTION, NMR 20 STRUCTURES)
分子名称: ECTATOMIN
著者Nolde, D.E, Sobol, A.G, Pluzhnikov, K.A, Arseniev, A.S, Grishin, E.V.
登録日1995-08-16
公開日1995-12-07
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Three-dimensional structure of ectatomin from Ectatomma tuberculatum ant venom.
J.Biomol.NMR, 5, 1995
5OQK
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Solution NMR structure of truncated, human Hv1/VSOP (Voltage-gated proton channel)
分子名称: Voltage-gated hydrogen channel 1
著者Bayrhuber, M, Maslennikov, I, Kwiatowski, W, Sobol, A, Wierschem, C, Eichmann, C, Riek, R.
登録日2017-08-12
公開日2019-04-03
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Nuclear Magnetic Resonance Solution Structure and Functional Behavior of the Human Proton Channel.
Biochemistry, 58, 2019
1RQS
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NMR structure of C-terminal domain of ribosomal protein L7 from E.coli
分子名称: 50S ribosomal protein L7/L12
著者Bocharov, E.V, Sobol, A.G, Pavlov, K.V, Korzhnev, D.M, Jaravine, V.A, Gudkov, A.T, Arseniev, A.S.
登録日2003-12-07
公開日2004-03-02
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献From structure and dynamics of protein L7/L12 to molecular switching in ribosome.
J.Biol.Chem., 279, 2004
1RQU
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NMR structure of L7 dimer from E.coli
分子名称: 50S ribosomal protein L7/L12
著者Bocharov, E.V, Sobol, A.G, Pavlov, K.V, Korzhnev, D.M, Jaravine, V.A, Gudkov, A.T, Arseniev, A.S.
登録日2003-12-07
公開日2004-03-02
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献From structure and dynamics of protein L7/L12 to molecular switching in ribosome.
J.Biol.Chem., 279, 2004
1RQT
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NMR structure of dimeric N-terminal domain of ribosomal protein L7 from E.coli
分子名称: 50S ribosomal protein L7/L12
著者Bocharov, E.V, Sobol, A.G, Pavlov, K.V, Korzhnev, D.M, Jaravine, V.A, Gudkov, A.T, Arseniev, A.S.
登録日2003-12-07
公開日2004-03-02
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献From structure and dynamics of protein L7/L12 to molecular switching in ribosome.
J.Biol.Chem., 279, 2004
1RQV
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Spatial model of L7 dimer from E.coli with one hinge region in helical state
分子名称: 50S ribosomal protein L7/L12
著者Bocharov, E.V, Sobol, A.G, Pavlov, K.V, Korzhnev, D.M, Jaravine, V.A, Gudkov, A.T, Arseniev, A.S.
登録日2003-12-07
公開日2004-03-02
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献From structure and dynamics of protein L7/L12 to molecular switching in ribosome
J.Biol.Chem., 279, 2004
5WEL
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GluA2 bound to antagonist ZK and GSG1L in digitonin, state 2
分子名称: Chimera of Glutamate receptor 2, Germ cell-specific gene 1-like protein, Digitonin, ...
著者Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I.
登録日2017-07-10
公開日2017-08-02
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Channel opening and gating mechanism in AMPA-subtype glutamate receptors.
Nature, 549, 2017
5WEO
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Activated GluA2 complex bound to glutamate, cyclothiazide, and STZ in digitonin
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit chimera
著者Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I.
登録日2017-07-10
公開日2017-08-02
最終更新日2019-11-20
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Channel opening and gating mechanism in AMPA-subtype glutamate receptors.
Nature, 549, 2017
5WO7
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Crystal Structure of Transient Receptor Potential (TRP) channel TRPV6*
分子名称: 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6
著者Singh, A.K, Saotome, K, Sobolevsky, A.I.
登録日2017-08-01
公開日2017-09-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.246 Å)
主引用文献Swapping of transmembrane domains in the epithelial calcium channel TRPV6.
Sci Rep, 7, 2017
6O9G
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Open state GluA2 in complex with STZ and blocked by AgTx-636, after micelle signal subtraction
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit, ...
著者Twomey, E.C, Yelshanskaya, M.V, Vassilevski, A.A, Sobolevsky, A.I.
登録日2019-03-13
公開日2019-03-20
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Mechanisms of Channel Block in Calcium-Permeable AMPA Receptors.
Neuron, 99, 2018
7MIO
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Mouse TRPV3 in cNW11 nanodiscs, open state at 42 degrees Celsius
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3
著者Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I.
登録日2021-04-17
公開日2021-07-21
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel.
Nat.Struct.Mol.Biol., 28, 2021
7MIJ
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Mouse TRPV3 in MSP2N2 nanodiscs, closed state at 4 degrees Celsius
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3
著者Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I.
登録日2021-04-17
公開日2021-07-21
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (1.98 Å)
主引用文献Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel.
Nat.Struct.Mol.Biol., 28, 2021
7MIK
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Mouse TRPV3 in MSP2N2 nanodiscs, closed state at 42 degrees Celsius
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3
著者Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I.
登録日2021-04-17
公開日2021-07-21
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel.
Nat.Struct.Mol.Biol., 28, 2021
7MIL
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Mouse TRPV3 in MSP2N2 nanodiscs, sensitized state at 42 degrees Celsius
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3
著者Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I.
登録日2021-04-17
公開日2021-07-21
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (3.86 Å)
主引用文献Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel.
Nat.Struct.Mol.Biol., 28, 2021
7MIN
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Mouse TRPV3 in cNW11 nanodiscs, closed state at 42 degrees Celsius
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3
著者Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I.
登録日2021-04-17
公開日2021-07-21
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel.
Nat.Struct.Mol.Biol., 28, 2021
7MIM
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Mouse TRPV3 in cNW11 nanodiscs, closed state at 4 degrees Celsius
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 3
著者Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I.
登録日2021-04-17
公開日2021-07-21
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Structural mechanism of heat-induced opening of a temperature-sensitive TRP channel.
Nat.Struct.Mol.Biol., 28, 2021
9B37
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Open state of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to one concanavalin A dimer. Composite map.
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Nadezhdin, K.D, Gangwar, S.P, Sobolevsky, A.I.
登録日2024-03-18
公開日2024-05-22
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (6.66 Å)
主引用文献Kainate receptor channel opening and gating mechanism.
Nature, 630, 2024
9B36
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Open state of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to two concanavalin A dimers. Composite map.
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Nadezhdin, K.D, Gangwar, S.P, Sobolevsky, A.I.
登録日2024-03-18
公開日2024-05-22
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (4.29 Å)
主引用文献Kainate receptor channel opening and gating mechanism.
Nature, 630, 2024
9B34
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Structure of concanavalin A (ConA) dimer from the open-state structure of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to two ConA dimers. Type I interface between GluK2 ligand-binding domain and ConA
分子名称: CALCIUM ION, Concanavalin A, ZINC ION
著者Nadezhdin, K.D, Gangwar, S.P, Sobolevsky, A.I.
登録日2024-03-18
公開日2024-05-22
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Kainate receptor channel opening and gating mechanism.
Nature, 630, 2024
9B39
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Kainate receptor GluK2 in complex with agonist glutamate with asymmetric ligand-binding domain layer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
著者Nadezhdin, K.D, Gangwar, S.P, Sobolevsky, A.I.
登録日2024-03-18
公開日2024-05-22
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.84 Å)
主引用文献Kainate receptor channel opening and gating mechanism.
Nature, 630, 2024
9B33
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Structure of concanavalin A (ConA) dimer from the open-state structure of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to one ConA dimer. Type II interface between GluK2 ligand-binding domain and ConA
分子名称: CALCIUM ION, Concanavalin V, ZINC ION
著者Nadezhdin, K.D, Gangwar, S.P, Sobolevsky, A.I.
登録日2024-03-18
公開日2024-05-22
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (4.07 Å)
主引用文献Kainate receptor channel opening and gating mechanism.
Nature, 630, 2024
9B38
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Kainate receptor GluK2 in complex with agonist glutamate with pseudo 4-fold symmetrical ligand-binding domain layer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
著者Nadezhdin, K.D, Gangwar, S.P, Sobolevsky, A.I.
登録日2024-03-18
公開日2024-05-22
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Kainate receptor channel opening and gating mechanism.
Nature, 630, 2024

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件を2024-07-03に公開中

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